Motif ID: Hsf4
Z-value: 0.782

Transcription factors associated with Hsf4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hsf4 | ENSMUSG00000033249.4 | Hsf4 |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 145 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 6.3 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
1.0 | 6.1 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.6 | 4.2 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
1.4 | 4.1 | GO:0035799 | ureter maturation(GO:0035799) |
0.1 | 3.9 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
1.2 | 3.7 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
0.6 | 3.2 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.1 | 2.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 2.6 | GO:0015992 | proton transport(GO:0015992) |
0.6 | 2.5 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
0.6 | 2.5 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
0.2 | 2.5 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
0.4 | 2.2 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.1 | 2.1 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.6 | 1.9 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
0.3 | 1.9 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.1 | 1.9 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.4 | 1.8 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.4 | 1.8 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
0.1 | 1.8 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 66 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 6.3 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.1 | 5.9 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.0 | 4.2 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.2 | 3.8 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 3.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 3.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 3.3 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 3.2 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 3.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.2 | 2.8 | GO:0046930 | pore complex(GO:0046930) |
0.5 | 2.7 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.0 | 2.6 | GO:0030018 | Z disc(GO:0030018) |
0.2 | 2.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 2.2 | GO:0005874 | microtubule(GO:0005874) |
0.0 | 2.0 | GO:0005604 | basement membrane(GO:0005604) |
0.1 | 1.8 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 1.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 1.8 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.2 | 1.7 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.4 | 1.6 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 93 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 6.1 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.1 | 5.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.8 | 4.9 | GO:0002135 | CTP binding(GO:0002135) |
0.1 | 4.0 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.8 | 3.8 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.0 | 3.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.5 | 3.7 | GO:0043199 | sulfate binding(GO:0043199) |
0.1 | 3.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 3.3 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.0 | 2.9 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.1 | 2.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 2.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.2 | 2.2 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.2 | 2.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.5 | 1.9 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.2 | 1.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.3 | 1.8 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.1 | 1.8 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
0.2 | 1.7 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
0.2 | 1.6 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 24 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 6.3 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.1 | 5.7 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
0.1 | 5.4 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.0 | 3.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 3.3 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.0 | 2.2 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 1.9 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 1.9 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
0.0 | 1.7 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 1.6 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.3 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 1.2 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 1.2 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
0.1 | 0.9 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.1 | 0.8 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 0.8 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.0 | 0.8 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.6 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.0 | 0.6 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.0 | 0.5 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 41 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 9.8 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.3 | 6.3 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.7 | 4.2 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.2 | 3.7 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.1 | 3.5 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.1 | 3.5 | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | Genes involved in ABC-family proteins mediated transport |
0.1 | 2.0 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.1 | 1.8 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 1.7 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.1 | 1.6 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.1 | 1.4 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.1 | 1.4 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.1 | 1.1 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 1.1 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 1.0 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.0 | 1.0 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 1.0 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.3 | 0.9 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
0.0 | 0.8 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.8 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |