Motif ID: Hsfy2
Z-value: 1.294
Transcription factors associated with Hsfy2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hsfy2 | ENSMUSG00000045336.4 | Hsfy2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 10.4 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 1.9 | 5.6 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) |
| 1.7 | 5.2 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 1.6 | 4.9 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
| 1.5 | 4.4 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 1.5 | 10.2 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 1.4 | 9.7 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 1.3 | 5.3 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 1.3 | 3.8 | GO:0070366 | regulation of hepatocyte differentiation(GO:0070366) |
| 1.3 | 41.8 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 1.3 | 5.0 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 1.2 | 1.2 | GO:1904884 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 1.0 | 10.5 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.9 | 2.8 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) |
| 0.8 | 5.9 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.8 | 9.8 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.8 | 2.4 | GO:0002586 | positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) |
| 0.8 | 2.3 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
| 0.7 | 5.1 | GO:0070458 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
| 0.7 | 2.2 | GO:0002432 | granuloma formation(GO:0002432) |
| 0.7 | 2.1 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
| 0.7 | 2.7 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.6 | 3.1 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.6 | 2.9 | GO:1903232 | melanosome assembly(GO:1903232) |
| 0.6 | 6.2 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.6 | 1.1 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
| 0.5 | 3.3 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.5 | 1.6 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
| 0.5 | 0.5 | GO:0042323 | negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 0.5 | 0.5 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.5 | 1.4 | GO:0002159 | desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) |
| 0.5 | 2.4 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.5 | 1.8 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.4 | 2.2 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.4 | 2.6 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 0.4 | 3.0 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
| 0.4 | 8.0 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.4 | 2.5 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.4 | 2.8 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.4 | 2.0 | GO:0006537 | glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543) |
| 0.4 | 1.2 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.4 | 2.7 | GO:0021775 | smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) |
| 0.4 | 23.9 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.4 | 1.1 | GO:2000373 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 0.3 | 3.4 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
| 0.3 | 2.3 | GO:0071907 | determination of digestive tract left/right asymmetry(GO:0071907) |
| 0.3 | 2.9 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.3 | 17.3 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.3 | 1.3 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 0.3 | 1.8 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.3 | 17.3 | GO:0035307 | positive regulation of protein dephosphorylation(GO:0035307) |
| 0.3 | 2.3 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 0.3 | 3.4 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.3 | 3.3 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.3 | 3.3 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.3 | 3.2 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
| 0.3 | 1.1 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
| 0.3 | 1.8 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.3 | 1.8 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
| 0.3 | 1.3 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.2 | 1.2 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
| 0.2 | 5.2 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.2 | 0.7 | GO:0051715 | cytolysis in other organism(GO:0051715) |
| 0.2 | 3.0 | GO:0060068 | vagina development(GO:0060068) |
| 0.2 | 4.6 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.2 | 5.0 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
| 0.2 | 10.7 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.2 | 0.7 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.2 | 1.3 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
| 0.2 | 3.4 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.2 | 9.3 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.2 | 0.6 | GO:0042726 | flavin-containing compound metabolic process(GO:0042726) |
| 0.2 | 2.5 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.2 | 0.6 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.2 | 2.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.2 | 3.3 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.2 | 2.0 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.2 | 8.5 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
| 0.2 | 6.0 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.2 | 2.1 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
| 0.2 | 0.7 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
| 0.2 | 1.3 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.2 | 2.0 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.2 | 0.8 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 0.2 | 8.3 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.2 | 1.1 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.1 | 0.4 | GO:0033762 | response to glucagon(GO:0033762) |
| 0.1 | 1.7 | GO:0070508 | sterol import(GO:0035376) cholesterol import(GO:0070508) |
| 0.1 | 0.6 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.1 | 2.3 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.1 | 1.0 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.1 | 0.7 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 0.1 | 0.4 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 0.1 | 8.5 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.1 | 3.6 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 1.2 | GO:0098779 | protein import into mitochondrial outer membrane(GO:0045040) mitophagy in response to mitochondrial depolarization(GO:0098779) |
| 0.1 | 0.6 | GO:1900169 | glucocorticoid mediated signaling pathway(GO:0043402) regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.1 | 3.6 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 6.2 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.1 | 0.8 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.1 | 1.5 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.1 | 1.7 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
| 0.1 | 0.9 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.1 | 10.3 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
| 0.1 | 1.1 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.1 | 0.7 | GO:0036035 | osteoclast development(GO:0036035) |
| 0.1 | 0.3 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 0.1 | 3.7 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.1 | 0.6 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.1 | 4.6 | GO:0043297 | apical junction assembly(GO:0043297) |
| 0.1 | 0.3 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.1 | 0.3 | GO:0050684 | regulation of mRNA processing(GO:0050684) |
| 0.1 | 7.0 | GO:0007093 | mitotic cell cycle checkpoint(GO:0007093) |
| 0.1 | 2.4 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.1 | 0.3 | GO:0060368 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) |
| 0.1 | 4.3 | GO:0045843 | negative regulation of striated muscle tissue development(GO:0045843) |
| 0.1 | 0.9 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.1 | 1.1 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.1 | 3.4 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.1 | 5.6 | GO:0042476 | odontogenesis(GO:0042476) |
| 0.1 | 0.6 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.1 | 7.0 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.1 | 1.2 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.1 | 0.7 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.1 | 0.6 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.1 | 1.3 | GO:0033194 | response to hydroperoxide(GO:0033194) |
| 0.1 | 0.4 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.1 | 3.1 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.1 | 0.4 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.1 | 4.2 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.1 | 1.5 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.1 | 5.8 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.1 | 0.5 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.1 | 1.3 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.1 | 4.8 | GO:0000070 | mitotic sister chromatid segregation(GO:0000070) |
| 0.0 | 2.7 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
| 0.0 | 14.3 | GO:0008380 | RNA splicing(GO:0008380) |
| 0.0 | 0.7 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) DNA demethylation(GO:0080111) changes to DNA methylation involved in embryo development(GO:1901538) |
| 0.0 | 0.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.4 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.0 | 0.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 0.6 | GO:0035067 | negative regulation of histone acetylation(GO:0035067) |
| 0.0 | 0.5 | GO:0042407 | cristae formation(GO:0042407) |
| 0.0 | 1.6 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 0.0 | 0.5 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
| 0.0 | 0.5 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.0 | 0.2 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.0 | 0.4 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.0 | 1.5 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
| 0.0 | 0.5 | GO:0031440 | regulation of mRNA 3'-end processing(GO:0031440) |
| 0.0 | 0.8 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.5 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.0 | 0.2 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
| 0.0 | 0.1 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 1.1 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 0.2 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.0 | 0.9 | GO:0006914 | autophagy(GO:0006914) |
| 0.0 | 0.4 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.6 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.0 | 0.1 | GO:0034773 | histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) |
| 0.0 | 1.5 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 0.0 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.0 | 0.4 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.3 | 50.5 | GO:0005818 | aster(GO:0005818) |
| 3.0 | 11.9 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 2.7 | 8.0 | GO:1990423 | RZZ complex(GO:1990423) |
| 1.5 | 6.0 | GO:0008623 | CHRAC(GO:0008623) |
| 1.0 | 2.9 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.9 | 4.4 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.8 | 4.6 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.7 | 2.2 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
| 0.7 | 10.1 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.6 | 2.4 | GO:0061702 | inflammasome complex(GO:0061702) |
| 0.6 | 2.3 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.5 | 1.9 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.4 | 4.6 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.4 | 1.2 | GO:0000801 | central element(GO:0000801) |
| 0.4 | 3.0 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.3 | 10.2 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.3 | 1.8 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.3 | 18.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.3 | 9.9 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.2 | 3.7 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.2 | 1.1 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.2 | 0.6 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.2 | 1.0 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.2 | 1.8 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.2 | 0.6 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.2 | 0.4 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.2 | 2.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.2 | 9.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 0.7 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
| 0.1 | 2.7 | GO:0097526 | spliceosomal tri-snRNP complex(GO:0097526) |
| 0.1 | 2.8 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 1.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 0.7 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 8.2 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 6.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 0.9 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.1 | 1.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.1 | 0.7 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.1 | 3.6 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 2.7 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 1.2 | GO:0045095 | keratin filament(GO:0045095) |
| 0.1 | 7.8 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.1 | 6.8 | GO:0005657 | replication fork(GO:0005657) |
| 0.1 | 2.7 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.1 | 0.4 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.1 | 0.5 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.1 | 2.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 5.6 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.1 | 0.2 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.1 | 1.2 | GO:0001741 | XY body(GO:0001741) |
| 0.1 | 0.6 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.1 | 0.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.1 | 3.3 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.1 | 0.5 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.1 | 0.8 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 1.1 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 5.3 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 1.5 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 1.9 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 12.1 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 3.1 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 1.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 2.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 2.9 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 2.0 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 1.2 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.7 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 2.4 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 0.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.9 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 1.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 18.0 | GO:0005694 | chromosome(GO:0005694) |
| 0.0 | 2.3 | GO:0031514 | motile cilium(GO:0031514) |
| 0.0 | 3.4 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 6.1 | GO:0005929 | cilium(GO:0005929) |
| 0.0 | 3.4 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 2.4 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.9 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.7 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.6 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 1.8 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.0 | 0.4 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.2 | GO:0005667 | transcription factor complex(GO:0005667) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 36.6 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 3.3 | 13.3 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 2.1 | 10.7 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 2.0 | 5.9 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 1.7 | 10.5 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 1.6 | 4.9 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 1.5 | 10.2 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 1.1 | 10.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 1.1 | 5.6 | GO:0050700 | CARD domain binding(GO:0050700) |
| 1.1 | 3.3 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 1.1 | 9.8 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 1.1 | 5.3 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 1.0 | 2.9 | GO:0035651 | AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651) |
| 0.8 | 4.8 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.6 | 5.2 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.6 | 3.2 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.6 | 3.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.6 | 2.5 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.6 | 3.5 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.6 | 1.7 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.6 | 3.4 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.5 | 3.7 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.5 | 1.6 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 0.5 | 1.6 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.5 | 3.3 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.5 | 2.3 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.5 | 6.0 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.5 | 1.4 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.4 | 1.3 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.4 | 2.1 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
| 0.4 | 2.0 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.4 | 6.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.4 | 3.7 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.3 | 2.1 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.3 | 2.4 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.3 | 1.5 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.3 | 1.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.3 | 3.0 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.3 | 5.2 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.3 | 4.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.3 | 1.0 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
| 0.2 | 3.0 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.2 | 3.3 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.2 | 19.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 5.1 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.2 | 1.0 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.2 | 5.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 1.2 | GO:0032405 | MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407) |
| 0.2 | 2.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.2 | 3.1 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.2 | 3.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.2 | 3.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 0.6 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.2 | 4.1 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.2 | 1.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 0.6 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.1 | 0.8 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 1.2 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.1 | 1.1 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.1 | 0.7 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.1 | 0.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 0.9 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
| 0.1 | 0.6 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.1 | 5.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 0.7 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.1 | 0.6 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.1 | 2.1 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 0.3 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.1 | 0.6 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 1.2 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.1 | 1.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 0.5 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 2.6 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 3.6 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 0.8 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 0.6 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.5 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.7 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 1.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 5.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 0.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.1 | 12.4 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.1 | 0.6 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 4.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.2 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.1 | 1.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 0.9 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.0 | 1.1 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.4 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.0 | 0.5 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 1.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 1.6 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 0.0 | 0.7 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.0 | 1.5 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.7 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 1.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
| 0.0 | 0.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 1.5 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 0.8 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.1 | GO:0004103 | choline kinase activity(GO:0004103) |
| 0.0 | 1.5 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 1.2 | GO:0015370 | solute:sodium symporter activity(GO:0015370) |
| 0.0 | 0.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 4.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 2.3 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.1 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.0 | 1.3 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 2.8 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.0 | 4.2 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.3 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 1.9 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.0 | 0.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 0.1 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.0 | 0.9 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.6 | GO:0001540 | beta-amyloid binding(GO:0001540) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 36.6 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.7 | 5.9 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.3 | 10.1 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.3 | 11.6 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.2 | 7.2 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.2 | 8.5 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.2 | 5.0 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.2 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.1 | 4.3 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 2.8 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 4.6 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.1 | 4.2 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.1 | 3.1 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 4.0 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 1.2 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.4 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 2.7 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 3.8 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.8 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.6 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 1.4 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.4 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.9 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.5 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 1.1 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.5 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.5 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 0.2 | PID_ATM_PATHWAY | ATM pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 7.0 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.6 | 2.8 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
| 0.5 | 4.7 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.5 | 4.1 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.4 | 10.2 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.4 | 2.4 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.4 | 10.4 | REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.4 | 2.3 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.2 | 9.4 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 5.1 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 2.0 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 2.5 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.1 | 2.3 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 7.0 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.1 | 1.7 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
| 0.1 | 4.6 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 6.0 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.1 | 2.9 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 12.5 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 0.3 | REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.1 | 1.7 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.1 | 4.0 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.1 | 1.8 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 2.0 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 4.4 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 2.8 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 1.5 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 1.6 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 1.2 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 1.5 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 1.5 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 2.3 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.1 | 1.5 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.7 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.9 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 3.6 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.7 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
| 0.0 | 1.8 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 4.3 | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | Genes involved in G alpha (q) signalling events |
| 0.0 | 0.3 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 1.0 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.5 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 1.1 | REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 0.0 | 0.3 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.0 | 1.5 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.9 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.5 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.6 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.7 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.6 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
