Motif ID: Id4

Z-value: 0.889


Transcription factors associated with Id4:

Gene SymbolEntrez IDGene Name
Id4 ENSMUSG00000021379.1 Id4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Id4mm10_v2_chr13_+_48261427_482614270.104.7e-01Click!


Activity profile for motif Id4.

activity profile for motif Id4


Sorted Z-values histogram for motif Id4

Sorted Z-values for motif Id4



Network of associatons between targets according to the STRING database.



First level regulatory network of Id4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66831625 6.706 ENSMUST00000164163.1
Sla
src-like adaptor
chr11_-_67922136 6.295 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr3_-_82145865 5.471 ENSMUST00000048976.6
Gucy1a3
guanylate cyclase 1, soluble, alpha 3
chr15_-_98677451 3.889 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
Rnd1


Rho family GTPase 1


chr4_+_125490688 3.834 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr2_+_70562007 3.325 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr14_-_103843685 3.225 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr11_+_42419729 3.192 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr2_+_70562147 3.138 ENSMUST00000148210.1
Gad1
glutamate decarboxylase 1
chr16_+_91269759 3.051 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr12_+_82616885 2.951 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr8_-_4217133 2.834 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr8_-_70439557 2.796 ENSMUST00000076615.5
Crtc1
CREB regulated transcription coactivator 1
chr3_+_145758674 2.765 ENSMUST00000029845.8
Ddah1
dimethylarginine dimethylaminohydrolase 1
chr13_+_83504032 2.449 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr5_-_67847360 2.353 ENSMUST00000072971.6
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr12_+_3806513 2.352 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr15_-_71727815 2.324 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr14_-_103844173 2.304 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr2_-_93334467 2.294 ENSMUST00000111265.2
Tspan18
tetraspanin 18
chr17_-_25570678 2.258 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr8_-_4217459 2.240 ENSMUST00000176227.1
BC068157
cDNA sequence BC068157
chr19_+_36409719 2.222 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr13_-_57907587 2.201 ENSMUST00000172326.1
Spock1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
chr6_+_17307272 2.065 ENSMUST00000115454.1
Cav1
caveolin 1, caveolae protein
chr4_-_137766474 2.032 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr8_-_4216912 1.999 ENSMUST00000177491.1
BC068157
cDNA sequence BC068157
chr4_+_104367549 1.980 ENSMUST00000106830.2
Dab1
disabled 1
chr7_+_126847908 1.951 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr2_+_130406478 1.949 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr2_-_122611238 1.919 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_+_37028329 1.857 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr3_+_89436736 1.851 ENSMUST00000146630.1
ENSMUST00000145753.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr1_+_86045863 1.849 ENSMUST00000165824.1
2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr19_-_57314896 1.829 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr4_+_102087543 1.782 ENSMUST00000106911.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr12_-_91779129 1.758 ENSMUST00000170077.1
Ston2
stonin 2
chr11_-_7213897 1.748 ENSMUST00000020702.4
ENSMUST00000135887.2
Igfbp3

insulin-like growth factor binding protein 3

chr5_+_32136458 1.731 ENSMUST00000031017.9
Fosl2
fos-like antigen 2
chr8_+_70493156 1.725 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr14_-_121797670 1.725 ENSMUST00000100299.3
Dock9
dedicator of cytokinesis 9
chr16_+_11984581 1.721 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chr10_+_123264076 1.700 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr9_-_108263887 1.661 ENSMUST00000166905.1
ENSMUST00000080435.2
Dag1

dystroglycan 1

chr9_-_108263706 1.656 ENSMUST00000171412.1
Dag1
dystroglycan 1
chr10_+_89873497 1.645 ENSMUST00000183156.1
ENSMUST00000182936.1
ENSMUST00000099368.4
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr15_-_60824942 1.632 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr5_-_67847400 1.621 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
Atp8a1


ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1


chr7_-_116308241 1.620 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
Plekha7


pleckstrin homology domain containing, family A member 7


chr15_-_98004634 1.617 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr6_+_17307632 1.613 ENSMUST00000115453.1
Cav1
caveolin 1, caveolae protein
chr8_+_36457548 1.609 ENSMUST00000135373.1
ENSMUST00000147525.1
6430573F11Rik

RIKEN cDNA 6430573F11 gene

chr5_+_66745835 1.602 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr15_-_37791993 1.591 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr9_+_35423582 1.590 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr16_+_13256481 1.585 ENSMUST00000009713.7
ENSMUST00000115809.1
Mkl2

MKL/myocardin-like 2

chr14_-_30353468 1.563 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr14_+_101840602 1.560 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr1_+_87327044 1.554 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr15_-_98004695 1.547 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr7_-_46099752 1.520 ENSMUST00000180081.1
Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr6_+_4902913 1.517 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr10_+_81257277 1.510 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
Matk


megakaryocyte-associated tyrosine kinase


chr1_-_180483410 1.502 ENSMUST00000136521.1
ENSMUST00000179826.1
6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr4_-_137796350 1.475 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr2_+_163225363 1.452 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr10_-_127341583 1.446 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr3_+_89436699 1.444 ENSMUST00000038942.3
ENSMUST00000130858.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr7_-_29505447 1.439 ENSMUST00000183096.1
ENSMUST00000085809.4
Sipa1l3

signal-induced proliferation-associated 1 like 3

chr11_+_68692070 1.435 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chrX_+_100730178 1.433 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr10_-_58675631 1.422 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr6_-_37299950 1.407 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr3_-_158562199 1.362 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr11_+_19924403 1.331 ENSMUST00000093298.5
Spred2
sprouty-related, EVH1 domain containing 2
chr2_-_52335134 1.323 ENSMUST00000075301.3
Neb
nebulin
chr14_+_31019183 1.322 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr11_+_115163333 1.319 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr9_+_44134562 1.318 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr3_-_84305385 1.306 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr14_+_31019159 1.296 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr11_-_51756378 1.279 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24a


Sec24 related gene family, member A (S. cerevisiae)


chr16_-_34263179 1.277 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr7_+_25282784 1.271 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr8_-_40634750 1.268 ENSMUST00000173957.1
Mtmr7
myotubularin related protein 7
chr1_+_87327008 1.261 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr7_-_25250720 1.259 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr4_+_58943575 1.258 ENSMUST00000107554.1
Zkscan16
zinc finger with KRAB and SCAN domains 16
chr7_+_130936172 1.256 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr8_+_12873793 1.252 ENSMUST00000156560.1
ENSMUST00000095456.3
Mcf2l

mcf.2 transforming sequence-like

chr13_+_16011851 1.247 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr14_+_101840501 1.246 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr3_+_121723515 1.219 ENSMUST00000029771.8
F3
coagulation factor III
chr14_-_62292959 1.217 ENSMUST00000063169.8
Dleu7
deleted in lymphocytic leukemia, 7
chr7_-_14562171 1.211 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr12_-_76709997 1.211 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr9_-_114933811 1.177 ENSMUST00000084853.3
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr8_+_15011025 1.154 ENSMUST00000069399.6
Kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr5_+_35757875 1.151 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
Ablim2



actin-binding LIM protein 2



chr16_-_34262830 1.145 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase
chr13_-_60177357 1.139 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr5_-_135251209 1.133 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr11_+_7063423 1.129 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr5_-_92042630 1.121 ENSMUST00000113140.1
ENSMUST00000113143.1
Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr18_-_38211957 1.117 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1

protocadherin 1

chr2_+_112265809 1.106 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr5_+_98854434 1.102 ENSMUST00000031278.4
Bmp3
bone morphogenetic protein 3
chr2_+_19909769 1.095 ENSMUST00000114610.1
Etl4
enhancer trap locus 4
chr14_+_64652524 1.087 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr9_-_112234956 1.074 ENSMUST00000162097.1
ENSMUST00000159055.1
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr14_-_102982630 1.067 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr15_-_72034202 1.066 ENSMUST00000159993.1
Col22a1
collagen, type XXII, alpha 1
chr9_-_95845215 1.063 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr1_+_87403705 1.058 ENSMUST00000172736.1
Gigyf2
GRB10 interacting GYF protein 2
chr14_-_34201604 1.058 ENSMUST00000096019.2
Gprin2
G protein regulated inducer of neurite outgrowth 2
chr7_-_66427469 1.040 ENSMUST00000015278.7
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr12_-_4592927 1.035 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr8_-_13677575 1.029 ENSMUST00000117551.2
Rasa3
RAS p21 protein activator 3
chr19_+_8664005 1.028 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr1_-_119053339 1.028 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr2_-_5714490 1.025 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr8_+_20136455 1.020 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811

predicted gene, 21811

chr3_+_65528457 0.998 ENSMUST00000130705.1
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chrX_+_143518671 0.995 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr5_+_134986191 0.992 ENSMUST00000094245.2
Cldn3
claudin 3
chr12_+_4592992 0.992 ENSMUST00000062580.7
Itsn2
intersectin 2
chr10_-_81407641 0.988 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr13_+_42681513 0.984 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr1_+_132008285 0.975 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr1_-_164458345 0.950 ENSMUST00000027863.7
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_-_64737735 0.950 ENSMUST00000063982.5
ENSMUST00000116133.2
Fzd5

frizzled homolog 5 (Drosophila)

chr17_+_32036098 0.949 ENSMUST00000081339.6
Rrp1b
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr7_-_89517576 0.939 ENSMUST00000041761.5
Prss23
protease, serine, 23
chr16_-_34262945 0.936 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr7_-_131410325 0.932 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr3_-_121263159 0.931 ENSMUST00000128909.1
Tmem56
transmembrane protein 56
chr18_-_38209762 0.925 ENSMUST00000057185.6
Pcdh1
protocadherin 1
chr6_+_17307040 0.923 ENSMUST00000123439.1
Cav1
caveolin 1, caveolae protein
chr7_-_80401707 0.920 ENSMUST00000120753.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr1_-_153332724 0.920 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr7_-_27337667 0.918 ENSMUST00000038618.6
ENSMUST00000108369.2
Ltbp4

latent transforming growth factor beta binding protein 4

chr8_-_113848615 0.917 ENSMUST00000093113.4
Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr6_+_4903350 0.917 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr8_+_120537423 0.914 ENSMUST00000118136.1
Gse1
genetic suppressor element 1
chr3_+_137623672 0.912 ENSMUST00000053855.7
Ddit4l
DNA-damage-inducible transcript 4-like
chr14_+_101729907 0.911 ENSMUST00000100337.3
Lmo7
LIM domain only 7
chr11_+_77348272 0.910 ENSMUST00000181283.1
Ssh2
slingshot homolog 2 (Drosophila)
chr3_-_121263314 0.904 ENSMUST00000029777.7
Tmem56
transmembrane protein 56
chr4_+_119814495 0.903 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr13_-_93499803 0.897 ENSMUST00000065537.7
Jmy
junction-mediating and regulatory protein
chr9_+_122117258 0.886 ENSMUST00000146832.1
ENSMUST00000139181.1
Snrk

SNF related kinase

chr7_+_123982799 0.885 ENSMUST00000106437.1
Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr9_-_40455670 0.883 ENSMUST00000165104.1
ENSMUST00000045682.5
Gramd1b

GRAM domain containing 1B

chr4_-_155222535 0.882 ENSMUST00000084103.3
ENSMUST00000030917.5
Ski

ski sarcoma viral oncogene homolog (avian)

chr5_-_5266038 0.866 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr7_+_4137475 0.864 ENSMUST00000154571.1
Leng8
leukocyte receptor cluster (LRC) member 8
chr19_-_10304867 0.863 ENSMUST00000039327.4
Dagla
diacylglycerol lipase, alpha
chr4_+_57434247 0.863 ENSMUST00000102905.1
Palm2
paralemmin 2
chr18_+_60925612 0.860 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr11_+_111066154 0.857 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_+_53440388 0.849 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr5_-_148399901 0.846 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_+_4903298 0.841 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr9_-_112217261 0.837 ENSMUST00000159451.1
ENSMUST00000162796.1
ENSMUST00000161097.1
Arpp21


cyclic AMP-regulated phosphoprotein, 21


chr8_+_109868586 0.833 ENSMUST00000179721.1
ENSMUST00000034175.4
Phlpp2

PH domain and leucine rich repeat protein phosphatase 2

chr2_+_62664279 0.829 ENSMUST00000028257.2
Gca
grancalcin
chr9_+_30942541 0.827 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr16_+_32608973 0.825 ENSMUST00000120680.1
Tfrc
transferrin receptor
chr16_-_52452654 0.817 ENSMUST00000168071.1
Alcam
activated leukocyte cell adhesion molecule
chr16_+_36875119 0.809 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr1_+_75400070 0.808 ENSMUST00000113589.1
Speg
SPEG complex locus
chr13_-_34345174 0.801 ENSMUST00000040336.5
Slc22a23
solute carrier family 22, member 23
chr11_+_63128973 0.799 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr12_+_108334341 0.796 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr1_+_158362330 0.792 ENSMUST00000170718.1
Astn1
astrotactin 1
chr2_-_39190687 0.788 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr7_+_67952817 0.786 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chrX_-_162643575 0.783 ENSMUST00000101102.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr1_+_165788681 0.781 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr9_+_102718424 0.780 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chr9_-_111690313 0.779 ENSMUST00000035083.7
Stac
src homology three (SH3) and cysteine rich domain
chr5_-_92042999 0.774 ENSMUST00000069937.4
ENSMUST00000086978.5
Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr6_-_22356176 0.773 ENSMUST00000081288.7
Fam3c
family with sequence similarity 3, member C
chr1_+_66175272 0.772 ENSMUST00000156636.2
Map2
microtubule-associated protein 2
chr9_+_107935876 0.772 ENSMUST00000035700.8
Camkv
CaM kinase-like vesicle-associated
chr11_-_74590065 0.772 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr11_+_53519871 0.771 ENSMUST00000120878.2
Sept8
septin 8
chr19_-_56548013 0.769 ENSMUST00000182059.1
Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr7_+_3303503 0.768 ENSMUST00000100301.4
Prkcg
protein kinase C, gamma
chr11_-_72207413 0.768 ENSMUST00000108505.1
4933427D14Rik
RIKEN cDNA 4933427D14 gene
chr3_+_68584154 0.761 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr5_-_147076482 0.760 ENSMUST00000016664.7
Lnx2
ligand of numb-protein X 2
chr19_-_41743665 0.756 ENSMUST00000025993.3
Slit1
slit homolog 1 (Drosophila)
chr10_+_67096456 0.749 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chr11_+_53519920 0.748 ENSMUST00000147912.1
Sept8
septin 8
chr19_-_24555819 0.748 ENSMUST00000112673.2
ENSMUST00000025800.8
Pip5k1b

phosphatidylinositol-4-phosphate 5-kinase, type 1 beta

chrX_-_162643629 0.745 ENSMUST00000112334.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr17_-_51831884 0.745 ENSMUST00000124222.1
Satb1
special AT-rich sequence binding protein 1
chr4_-_151108244 0.744 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr7_+_126862431 0.742 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
1.1 5.5 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
1.1 3.3 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.9 2.8 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.9 6.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.9 4.6 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.9 2.7 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.8 3.3 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.8 2.4 GO:0007521 muscle cell fate determination(GO:0007521) positive regulation of macrophage apoptotic process(GO:2000111)
0.7 2.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.7 2.0 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.6 1.9 GO:0072034 renal vesicle induction(GO:0072034)
0.6 1.9 GO:0006601 creatine biosynthetic process(GO:0006601)
0.6 2.4 GO:0060032 notochord regression(GO:0060032)
0.6 4.0 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.5 3.4 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.5 1.4 GO:0046959 habituation(GO:0046959)
0.5 1.9 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.4 1.3 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.4 1.7 GO:2000832 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) negative regulation of steroid hormone secretion(GO:2000832) regulation of androgen secretion(GO:2000834) regulation of testosterone secretion(GO:2000843)
0.4 1.7 GO:0090472 dibasic protein processing(GO:0090472)
0.4 1.2 GO:0019085 early viral transcription(GO:0019085)
0.4 1.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.4 1.6 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.4 2.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.4 0.7 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.4 1.8 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799)
0.4 0.4 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.4 3.2 GO:0071420 cellular response to histamine(GO:0071420)
0.4 1.1 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.4 1.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 3.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3 1.0 GO:0060166 olfactory pit development(GO:0060166)
0.3 1.0 GO:0036292 DNA rewinding(GO:0036292)
0.3 0.7 GO:0097350 neutrophil clearance(GO:0097350)
0.3 2.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.3 0.9 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 1.5 GO:0032423 regulation of mismatch repair(GO:0032423)
0.3 2.4 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.3 0.9 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 3.4 GO:0060174 limb bud formation(GO:0060174)
0.3 0.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.3 0.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.3 1.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.3 1.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.2 3.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.2 0.5 GO:0060596 mammary placode formation(GO:0060596)
0.2 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 1.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.7 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.7 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 0.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 0.6 GO:1904173 regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.2 1.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 3.4 GO:0016322 neuron remodeling(GO:0016322)
0.2 0.8 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.2 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 1.6 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 2.0 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.8 GO:0044849 estrous cycle(GO:0044849) cholangiocyte apoptotic process(GO:1902488) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.2 0.6 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 0.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 0.7 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.2 0.4 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.2 1.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 0.9 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 0.5 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 0.9 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 0.7 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 0.8 GO:0015871 choline transport(GO:0015871)
0.2 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.5 GO:0003162 atrioventricular node development(GO:0003162)
0.2 0.7 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 0.5 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 1.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 1.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 0.8 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.2 1.1 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.2 0.5 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 0.5 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 0.5 GO:0035106 operant conditioning(GO:0035106)
0.2 0.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.6 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 0.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.6 GO:1990379 lipid transport across blood brain barrier(GO:1990379)
0.1 0.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.7 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.1 1.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.6 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.4 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.1 1.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.4 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.6 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 0.6 GO:0006868 glutamine transport(GO:0006868)
0.1 1.1 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 0.6 GO:0033034 positive regulation of myeloid cell apoptotic process(GO:0033034)
0.1 0.9 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 3.8 GO:0061157 mRNA destabilization(GO:0061157)
0.1 1.4 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 0.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 5.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 7.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.7 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.6 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.1 0.7 GO:0032264 IMP salvage(GO:0032264)
0.1 0.6 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.7 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 0.9 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.3 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.3 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.1 0.3 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.1 0.9 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 1.0 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.8 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 1.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.9 GO:0033198 response to ATP(GO:0033198)
0.1 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.2 GO:1903286 regulation of potassium ion import(GO:1903286)
0.1 0.3 GO:1900220 negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 1.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 1.3 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 0.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 1.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.3 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.3 GO:0032570 response to progesterone(GO:0032570)
0.1 0.9 GO:0036065 fucosylation(GO:0036065)
0.1 0.5 GO:0048484 enteric nervous system development(GO:0048484)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.3 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.1 0.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.3 GO:1905245 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) regulation of aspartic-type peptidase activity(GO:1905245)
0.1 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.8 GO:0032060 bleb assembly(GO:0032060)
0.1 0.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.2 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.5 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 1.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.7 GO:0033572 transferrin transport(GO:0033572)
0.1 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.1 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.1 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.2 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.4 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0060923 muscle cell fate commitment(GO:0042693) cardiac muscle cell fate commitment(GO:0060923)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.4 GO:0071380 response to caffeine(GO:0031000) cellular response to prostaglandin stimulus(GO:0071379) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.3 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.1 2.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.3 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 2.3 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 5.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.4 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
0.0 0.8 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.4 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 3.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.0 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 2.2 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.7 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1903011 negative regulation of bone development(GO:1903011)
0.0 0.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.8 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.6 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.4 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.2 GO:0045760 positive regulation of action potential(GO:0045760)
0.0 0.2 GO:0042148 strand invasion(GO:0042148)
0.0 0.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.7 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.0 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.3 GO:0014842 skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.0 0.4 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.0 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.6 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0046709 adenosine to inosine editing(GO:0006382) IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0045056 transcytosis(GO:0045056)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 1.3 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 5.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 1.4 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.1 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.5 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.5 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.4 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.4 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.3 GO:0006821 chloride transport(GO:0006821)
0.0 0.3 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.0 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 1.7 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0015992 proton transport(GO:0015992)
0.0 0.7 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 0.2 GO:1901216 positive regulation of neuron death(GO:1901216)
0.0 0.6 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.2 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.2 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.0 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.0 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.3 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.2 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.3 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.3 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:1990761 growth cone lamellipodium(GO:1990761)
0.6 1.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.6 3.3 GO:0016011 dystroglycan complex(GO:0016011)
0.5 1.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.5 1.4 GO:0043512 inhibin A complex(GO:0043512)
0.4 1.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 1.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 1.1 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.4 4.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 2.1 GO:0097513 myosin II filament(GO:0097513)
0.3 6.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 3.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 0.8 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 4.1 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.3 GO:0008091 spectrin(GO:0008091)
0.2 3.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 3.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 6.5 GO:0060077 inhibitory synapse(GO:0060077)
0.2 2.4 GO:0097542 ciliary tip(GO:0097542)
0.2 2.0 GO:0005915 zonula adherens(GO:0005915)
0.2 0.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 1.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 0.5 GO:0044194 cytolytic granule(GO:0044194)
0.2 0.6 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.2 0.5 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 4.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.1 GO:0033269 internode region of axon(GO:0033269)
0.1 0.7 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.3 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.7 GO:0071439 clathrin complex(GO:0071439)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 1.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.8 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:0005940 septin ring(GO:0005940)
0.1 2.1 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 13.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.1 GO:0043194 axon initial segment(GO:0043194)
0.1 0.5 GO:1902710 GABA receptor complex(GO:1902710)
0.1 2.3 GO:0001741 XY body(GO:0001741)
0.1 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.3 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 2.7 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 0.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.2 GO:0044299 C-fiber(GO:0044299)
0.1 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.7 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.8 GO:0043218 compact myelin(GO:0043218)
0.1 1.1 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.9 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.2 GO:1990423 RZZ complex(GO:1990423)
0.1 1.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0001533 cornified envelope(GO:0001533)
0.1 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.7 GO:0043196 varicosity(GO:0043196)
0.1 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.3 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.9 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.9 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.0 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 7.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 2.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.3 GO:0030017 sarcomere(GO:0030017)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.0 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 5.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 3.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 3.1 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.9 6.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.9 4.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.9 3.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.9 4.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.8 3.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.6 3.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.6 6.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.5 1.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.5 1.5 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.4 3.3 GO:0043237 laminin-1 binding(GO:0043237)
0.3 1.7 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.3 2.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 1.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 2.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 1.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 1.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 2.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.7 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.2 1.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 0.9 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 2.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.7 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.6 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.2 0.6 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 2.2 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.7 GO:0051378 serotonin binding(GO:0051378)
0.2 0.9 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 4.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 8.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 1.7 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 4.2 GO:0070064 proline-rich region binding(GO:0070064)
0.2 0.5 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2 1.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 1.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 1.0 GO:0071253 connexin binding(GO:0071253)
0.1 4.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.8 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 2.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.5 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 3.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 2.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 2.0 GO:0035198 miRNA binding(GO:0035198)
0.1 0.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.3 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 2.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.7 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.0 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.4 GO:0015265 urea channel activity(GO:0015265)
0.1 0.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 2.3 GO:0042805 actinin binding(GO:0042805)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.9 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 5.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.7 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.3 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.1 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 1.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 1.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 1.8 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.0 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 3.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 2.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 5.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.2 GO:0005525 GTP binding(GO:0005525)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 1.6 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 1.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.2 6.4 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 1.1 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 3.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 9.0 PID_ENDOTHELIN_PATHWAY Endothelins
0.1 0.4 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 4.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 1.1 PID_IGF1_PATHWAY IGF1 pathway
0.1 4.3 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 3.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.5 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 0.6 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.0 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 8.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 3.2 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 2.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 2.6 NABA_COLLAGENS Genes encoding collagen proteins
0.1 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.1 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.1 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 2.5 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.9 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.9 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 2.3 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.6 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.4 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.0 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.9 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.4 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.2 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.2 PID_FGF_PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.3 1.9 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 5.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 6.5 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 3.9 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 4.3 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 4.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.7 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 0.7 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.2 5.0 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 2.3 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 5.7 REACTOME_ION_CHANNEL_TRANSPORT Genes involved in Ion channel transport
0.1 3.9 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 3.7 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 4.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.3 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.7 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.5 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 1.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 1.2 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.4 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.2 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.9 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.4 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 0.7 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 5.6 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.1 1.1 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 0.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.1 0.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.0 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.7 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 1.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 1.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein