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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_155276297	24.776	ENSMUST00000029128.3	Map1lc3a	microtubule-associated protein 1 light chain 3 alpha
chr7_-_142095266	18.788	ENSMUST00000039926.3	Dusp8	dual specificity phosphatase 8
chr14_+_66344369	18.164	ENSMUST00000118426.1 ENSMUST00000121955.1 ENSMUST00000120229.1 ENSMUST00000134440.1	Stmn4	stathmin-like 4
chr6_+_54681687	18.053	ENSMUST00000046276.6	2410066E13Rik	RIKEN cDNA 2410066E13 gene
chr14_+_66344296	17.769	ENSMUST00000152093.1 ENSMUST00000074523.6	Stmn4	stathmin-like 4
chr9_-_98032983	15.164	ENSMUST00000162295.1	Clstn2	calsyntenin 2
chr9_-_98033181	12.854	ENSMUST00000035027.6	Clstn2	calsyntenin 2
chr13_-_54688264	12.469	ENSMUST00000150626.1 ENSMUST00000134177.1	Rnf44	ring finger protein 44
chr9_+_40269273	9.544	ENSMUST00000176185.1	Scn3b	sodium channel, voltage-gated, type III, beta
chr2_+_118663235	9.157	ENSMUST00000099557.3	Pak6	p21 protein (Cdc42/Rac)-activated kinase 6
chr6_-_124464772	9.113	ENSMUST00000008297.4	Clstn3	calsyntenin 3
chr9_+_40269202	9.100	ENSMUST00000114956.3 ENSMUST00000049941.5	Scn3b	sodium channel, voltage-gated, type III, beta
chr13_+_110395041	8.960	ENSMUST00000022212.7	Plk2	polo-like kinase 2
chr4_-_150652097	8.954	ENSMUST00000117997.1 ENSMUST00000037827.3	Slc45a1	solute carrier family 45, member 1
chr1_-_79440039	8.750	ENSMUST00000049972.4	Scg2	secretogranin II
chr11_-_30198232	8.386	ENSMUST00000102838.3	Sptbn1	spectrin beta, non-erythrocytic 1
chr13_-_54688246	8.270	ENSMUST00000122935.1 ENSMUST00000128257.1	Rnf44	ring finger protein 44
chr4_+_32238950	8.069	ENSMUST00000037416.6	Bach2	BTB and CNC homology 2
chr7_+_139248477	7.899	ENSMUST00000093993.3 ENSMUST00000172136.1	Pwwp2b	PWWP domain containing 2B
chr11_-_76571527	7.573	ENSMUST00000072740.6	Abr	active BCR-related gene
chr17_-_24689901	7.567	ENSMUST00000007236.4	Syngr3	synaptogyrin 3
chr8_-_70487314	7.565	ENSMUST00000045286.7	Tmem59l	transmembrane protein 59-like
chr4_+_102570065	7.446	ENSMUST00000097950.2	Pde4b	phosphodiesterase 4B, cAMP specific
chr11_+_83302817	7.118	ENSMUST00000142680.1	Ap2b1	adaptor-related protein complex 2, beta 1 subunit
chr5_+_101765120	7.097	ENSMUST00000031273.8	Cds1	CDP-diacylglycerol synthase 1
chr13_+_93303757	7.093	ENSMUST00000109494.1	Homer1	homer homolog 1 (Drosophila)
chr11_+_79660532	7.005	ENSMUST00000155381.1	Rab11fip4	RAB11 family interacting protein 4 (class II)
chr2_+_143546144	6.918	ENSMUST00000028905.9	Pcsk2	proprotein convertase subtilisin/kexin type 2
chr11_+_83302641	6.904	ENSMUST00000176430.1 ENSMUST00000065692.7	Ap2b1	adaptor-related protein complex 2, beta 1 subunit
chr11_+_52764634	6.876	ENSMUST00000036796.7	Fstl4	follistatin-like 4
chr16_-_16829276	6.802	ENSMUST00000023468.5	Spag6	sperm associated antigen 6
chr3_+_82358056	6.787	ENSMUST00000091014.4	Map9	microtubule-associated protein 9
chr13_+_5861489	6.752	ENSMUST00000000080.6	Klf6	Kruppel-like factor 6
chrX_-_20920911	6.575	ENSMUST00000081893.6 ENSMUST00000115345.1	Syn1	synapsin I
chr17_+_8849974	6.565	ENSMUST00000115720.1	Pde10a	phosphodiesterase 10A
chr1_-_71653162	6.507	ENSMUST00000055226.6	Fn1	fibronectin 1
chr4_+_85205120	6.435	ENSMUST00000107188.3	Sh3gl2	SH3-domain GRB2-like 2
chrX_+_143664365	6.380	ENSMUST00000126592.1 ENSMUST00000156449.1 ENSMUST00000155215.1 ENSMUST00000112865.1	Pak3	p21 protein (Cdc42/Rac)-activated kinase 3
chr7_+_121392266	6.360	ENSMUST00000084628.3	Hs3st2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr4_-_155345696	6.254	ENSMUST00000103178.4	Prkcz	protein kinase C, zeta
chr19_-_5085483	6.236	ENSMUST00000140389.1 ENSMUST00000151413.1 ENSMUST00000077066.7	Tmem151a	transmembrane protein 151A
chr13_-_54688184	6.227	ENSMUST00000150806.1 ENSMUST00000125927.1	Rnf44	ring finger protein 44
chr9_+_59578192	6.214	ENSMUST00000118549.1 ENSMUST00000034840.3	Celf6	CUGBP, Elav-like family member 6
chr6_-_92481343	6.212	ENSMUST00000113445.1	Prickle2	prickle homolog 2 (Drosophila)
chr2_-_140671440	6.180	ENSMUST00000099301.1	Flrt3	fibronectin leucine rich transmembrane protein 3
chr13_-_34077992	6.113	ENSMUST00000056427.8	Tubb2a	tubulin, beta 2A class IIA
chr4_+_21931291	5.994	ENSMUST00000029908.7	Faxc	failed axon connections homolog (Drosophila)
chr18_-_35215008	5.946	ENSMUST00000091636.3	Lrrtm2	leucine rich repeat transmembrane neuronal 2
chr15_-_84105662	5.935	ENSMUST00000082365.5	Sult4a1	sulfotransferase family 4A, member 1
chr4_+_42949814	5.887	ENSMUST00000037872.3 ENSMUST00000098112.2	Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5
chr17_-_46487641	5.859	ENSMUST00000047034.8	Ttbk1	tau tubulin kinase 1
chr17_-_26508463	5.849	ENSMUST00000025025.6	Dusp1	dual specificity phosphatase 1
chr11_+_103101682	5.639	ENSMUST00000107040.3 ENSMUST00000140372.1 ENSMUST00000024492.8 ENSMUST00000134884.1	Acbd4	acyl-Coenzyme A binding domain containing 4
chr12_-_86884808	5.622	ENSMUST00000038422.6	Irf2bpl	interferon regulatory factor 2 binding protein-like
chr4_+_85205417	5.528	ENSMUST00000030212.8 ENSMUST00000107189.1 ENSMUST00000107184.1	Sh3gl2	SH3-domain GRB2-like 2
chr13_-_99516537	5.335	ENSMUST00000064762.4	Map1b	microtubule-associated protein 1B
chr11_-_103101609	5.302	ENSMUST00000103077.1	Plcd3	phospholipase C, delta 3
chr1_+_71652837	5.237	ENSMUST00000097699.2	Apol7d	apolipoprotein L 7d
chr4_-_126753372	5.166	ENSMUST00000030637.7 ENSMUST00000106116.1	Ncdn	neurochondrin
chr8_+_23139030	5.111	ENSMUST00000121075.1	Ank1	ankyrin 1, erythroid
chr1_-_93101825	5.105	ENSMUST00000112958.2	Kif1a	kinesin family member 1A
chr7_-_126949499	5.044	ENSMUST00000106339.1 ENSMUST00000052937.5	Asphd1	aspartate beta-hydroxylase domain containing 1
chr1_-_3671498	5.033	ENSMUST00000070533.4	Xkr4	X Kell blood group precursor related family member 4
chr11_-_6606053	5.028	ENSMUST00000045713.3	Nacad	NAC alpha domain containing
chr7_+_25267669	4.990	ENSMUST00000169266.1	Cic	capicua homolog (Drosophila)
chr11_-_116412965	4.977	ENSMUST00000100202.3 ENSMUST00000106398.2	Rnf157	ring finger protein 157
chr4_+_102760135	4.961	ENSMUST00000066824.7	Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1
chr6_+_129533183	4.958	ENSMUST00000032264.6	Gabarapl1	gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr12_-_85151264	4.869	ENSMUST00000019379.7	Rps6kl1	ribosomal protein S6 kinase-like 1
chr12_+_4082596	4.867	ENSMUST00000049584.5	Dnajc27	DnaJ (Hsp40) homolog, subfamily C, member 27
chr9_+_113812547	4.865	ENSMUST00000166734.2 ENSMUST00000111838.2 ENSMUST00000163895.2	Clasp2	CLIP associating protein 2
chr12_+_117516479	4.855	ENSMUST00000109691.2	Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5
chrX_+_74309089	4.844	ENSMUST00000130581.1	Gdi1	guanosine diphosphate (GDP) dissociation inhibitor 1
chr13_-_54687644	4.821	ENSMUST00000129881.1	Rnf44	ring finger protein 44
chr2_+_155382186	4.798	ENSMUST00000134218.1	Trp53inp2	transformation related protein 53 inducible nuclear protein 2
chr12_-_55821157	4.785	ENSMUST00000110687.1 ENSMUST00000085385.5	Ralgapa1	Ral GTPase activating protein, alpha subunit 1
chr10_-_102490418	4.782	ENSMUST00000020040.3	Nts	neurotensin
chrX_+_143664290	4.773	ENSMUST00000112868.1	Pak3	p21 protein (Cdc42/Rac)-activated kinase 3
chr4_+_32238713	4.721	ENSMUST00000108180.2	Bach2	BTB and CNC homology 2
chr15_+_80091320	4.614	ENSMUST00000009728.6 ENSMUST00000009727.5	Syngr1	synaptogyrin 1
chr5_-_103211251	4.544	ENSMUST00000060871.5 ENSMUST00000112846.1 ENSMUST00000170792.1 ENSMUST00000112847.2	Mapk10	mitogen-activated protein kinase 10
chr10_+_29211637	4.524	ENSMUST00000092627.4	9330159F19Rik	RIKEN cDNA 9330159F19 gene
chr3_+_55461758	4.485	ENSMUST00000070418.4	Dclk1	doublecortin-like kinase 1
chr4_+_42950369	4.468	ENSMUST00000084662.5	Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5
chrX_-_8175890	4.429	ENSMUST00000143984.1	Tbc1d25	TBC1 domain family, member 25
chr9_+_109931774	4.412	ENSMUST00000169851.2	Map4	microtubule-associated protein 4
chr19_-_61228396	4.371	ENSMUST00000076046.6	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr3_-_127409014	4.342	ENSMUST00000182008.1 ENSMUST00000182711.1 ENSMUST00000182547.1	Ank2	ankyrin 2, brain
chr17_-_46890405	4.336	ENSMUST00000086675.3	A330017A19Rik	RIKEN cDNA A330017A19 gene
chr1_-_93101854	4.335	ENSMUST00000171796.1 ENSMUST00000171556.1	Kif1a	kinesin family member 1A
chr1_-_161034794	4.300	ENSMUST00000177003.1 ENSMUST00000162226.2 ENSMUST00000159250.2	Zbtb37	zinc finger and BTB domain containing 37
chr1_-_33907721	4.295	ENSMUST00000115161.1 ENSMUST00000062289.8	Bend6	BEN domain containing 6
chr17_-_33760306	4.293	ENSMUST00000173860.1	Rab11b	RAB11B, member RAS oncogene family
chrX_-_167209149	4.260	ENSMUST00000112176.1	Tmsb4x	thymosin, beta 4, X chromosome
chr9_+_102718424	4.248	ENSMUST00000156485.1 ENSMUST00000145937.1 ENSMUST00000134483.1	Amotl2	angiomotin-like 2
chr9_-_57467985	4.208	ENSMUST00000046587.6	Scamp5	secretory carrier membrane protein 5
chr6_-_113531575	4.183	ENSMUST00000032425.5	Emc3	ER membrane protein complex subunit 3
chr2_-_140671400	4.176	ENSMUST00000056760.3	Flrt3	fibronectin leucine rich transmembrane protein 3
chr10_+_110920170	4.175	ENSMUST00000020403.5	Csrp2	cysteine and glycine-rich protein 2
chr3_-_10440054	4.173	ENSMUST00000099223.4 ENSMUST00000029047.6	Snx16	sorting nexin 16
chr12_+_79130777	4.143	ENSMUST00000021550.6	Arg2	arginase type II
chr4_-_11966368	4.077	ENSMUST00000056050.4 ENSMUST00000108299.1 ENSMUST00000108297.2	Pdp1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_+_11728105	4.065	ENSMUST00000110909.2 ENSMUST00000033908.6	Arhgef7	Rho guanine nucleotide exchange factor (GEF7)
chr7_-_45366714	4.054	ENSMUST00000107779.1	Ppfia3	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr12_-_110682606	3.993	ENSMUST00000070659.5	1700001K19Rik	RIKEN cDNA 1700001K19 gene
chr10_+_121739915	3.980	ENSMUST00000065600.7 ENSMUST00000136432.1	BC048403	cDNA sequence BC048403
chr5_-_123666682	3.966	ENSMUST00000149410.1	Clip1	CAP-GLY domain containing linker protein 1
chr16_-_92400067	3.892	ENSMUST00000023672.8	Rcan1	regulator of calcineurin 1
chr8_+_25849618	3.890	ENSMUST00000098858.3	Kcnu1	potassium channel, subfamily U, member 1
chr3_-_127408937	3.886	ENSMUST00000183095.1 ENSMUST00000182610.1	Ank2	ankyrin 2, brain
chr2_-_57114970	3.879	ENSMUST00000028166.2	Nr4a2	nuclear receptor subfamily 4, group A, member 2
chr8_+_23139064	3.865	ENSMUST00000033947.8	Ank1	ankyrin 1, erythroid
chr11_-_70459957	3.840	ENSMUST00000019064.2	Cxcl16	chemokine (C-X-C motif) ligand 16
chr6_-_55681257	3.774	ENSMUST00000044767.8	Neurod6	neurogenic differentiation 6
chr6_-_149188648	3.754	ENSMUST00000095319.3 ENSMUST00000141346.1 ENSMUST00000111535.1	Amn1	antagonist of mitotic exit network 1
chr16_-_97962581	3.737	ENSMUST00000113734.2 ENSMUST00000052089.7 ENSMUST00000063605.7	Zbtb21	zinc finger and BTB domain containing 21
chr10_+_60106452	3.735	ENSMUST00000165024.2	Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr2_+_32095518	3.732	ENSMUST00000057423.5	Ppapdc3	phosphatidic acid phosphatase type 2 domain containing 3
chr14_+_101840501	3.716	ENSMUST00000159026.1	Lmo7	LIM domain only 7
chr11_+_98753512	3.712	ENSMUST00000124072.1	Thra	thyroid hormone receptor alpha
chr3_+_68584154	3.686	ENSMUST00000182997.1	Schip1	schwannomin interacting protein 1
chr7_+_24530645	3.650	ENSMUST00000049020.7	Irgq	immunity-related GTPase family, Q
chr2_+_132781278	3.648	ENSMUST00000028826.3	Chgb	chromogranin B
chr8_-_109251698	3.623	ENSMUST00000079189.3	4922502B01Rik	RIKEN cDNA 4922502B01 gene
chr9_-_44965519	3.592	ENSMUST00000125642.1 ENSMUST00000117506.1 ENSMUST00000117549.1	Ube4a	ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)
chr1_-_21961581	3.578	ENSMUST00000029667.6 ENSMUST00000173058.1 ENSMUST00000173404.1	Kcnq5	potassium voltage-gated channel, subfamily Q, member 5
chr7_+_92741603	3.572	ENSMUST00000032879.7	Rab30	RAB30, member RAS oncogene family
chr1_+_33908172	3.565	ENSMUST00000182513.1 ENSMUST00000183034.1	Dst	dystonin
chr2_+_178141920	3.553	ENSMUST00000103066.3	Phactr3	phosphatase and actin regulator 3
chr11_+_84129649	3.545	ENSMUST00000133811.1	Acaca	acetyl-Coenzyme A carboxylase alpha
chr12_+_71831064	3.541	ENSMUST00000085299.2	Daam1	dishevelled associated activator of morphogenesis 1
chr2_-_130840091	3.479	ENSMUST00000044766.8 ENSMUST00000138990.1 ENSMUST00000120316.1 ENSMUST00000110243.1	4930402H24Rik	RIKEN cDNA 4930402H24 gene
chr17_+_29660710	3.469	ENSMUST00000130423.1	Cmtr1	cap methyltransferase 1
chr5_+_143548700	3.434	ENSMUST00000169329.1 ENSMUST00000067145.5 ENSMUST00000119488.1 ENSMUST00000118121.1	Fam220a Fam220a	family with sequence similarity 220, member A family with sequence similarity 220, member A
chr2_+_30237680	3.385	ENSMUST00000113654.1 ENSMUST00000095078.2	Lrrc8a	leucine rich repeat containing 8A
chr10_+_60106198	3.348	ENSMUST00000121820.2	Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr9_-_45955170	3.334	ENSMUST00000162072.1	Sidt2	SID1 transmembrane family, member 2
chr12_+_24651346	3.324	ENSMUST00000020982.5	Klf11	Kruppel-like factor 11
chr17_-_84466186	3.319	ENSMUST00000047524.8	Thada	thyroid adenoma associated
chr9_+_21184103	3.316	ENSMUST00000115458.2	Pde4a	phosphodiesterase 4A, cAMP specific
chr8_-_24438937	3.312	ENSMUST00000052622.4	1810011O10Rik	RIKEN cDNA 1810011O10 gene
chr1_+_75479529	3.311	ENSMUST00000113575.2 ENSMUST00000148980.1 ENSMUST00000050899.6	Tmem198	transmembrane protein 198
chr9_+_109054839	3.304	ENSMUST00000154184.1	Shisa5	shisa homolog 5 (Xenopus laevis)
chr12_-_67222549	3.300	ENSMUST00000037181.8	Mdga2	MAM domain containing glycosylphosphatidylinositol anchor 2
chr9_-_51008936	3.299	ENSMUST00000176824.1 ENSMUST00000176663.1 ENSMUST00000041375.10	Sik2	salt inducible kinase 2
chr2_+_49619277	3.281	ENSMUST00000028102.7	Kif5c	kinesin family member 5C
chr5_-_24995748	3.245	ENSMUST00000076306.5	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr15_+_92161343	3.241	ENSMUST00000068378.5	Cntn1	contactin 1
chr3_+_89715016	3.187	ENSMUST00000098924.2	Adar	adenosine deaminase, RNA-specific
chr11_+_70029742	3.177	ENSMUST00000132597.2	Dlg4	discs, large homolog 4 (Drosophila)
chr2_+_136713444	3.170	ENSMUST00000028727.4 ENSMUST00000110098.3	Snap25	synaptosomal-associated protein 25
chr1_-_54926311	3.162	ENSMUST00000179030.1 ENSMUST00000044359.9	Ankrd44	ankyrin repeat domain 44
chr15_+_77084367	3.157	ENSMUST00000181870.1	1700109K24Rik	RIKEN cDNA 1700109K24 gene
chr10_-_17947997	3.142	ENSMUST00000037879.6	Heca	headcase homolog (Drosophila)
chr1_-_126738167	3.138	ENSMUST00000160693.1	Nckap5	NCK-associated protein 5
chr11_-_3504766	3.134	ENSMUST00000044507.5	Inpp5j	inositol polyphosphate 5-phosphatase J
chr16_-_4880284	3.121	ENSMUST00000037843.6	Ubald1	UBA-like domain containing 1
chr15_+_25843264	3.116	ENSMUST00000022881.7	Fam134b	family with sequence similarity 134, member B
chr1_-_166409773	3.114	ENSMUST00000135673.1 ENSMUST00000079972.6 ENSMUST00000169324.1 ENSMUST00000111411.2 ENSMUST00000128861.1	Pogk	pogo transposable element with KRAB domain
chr4_+_48045144	3.106	ENSMUST00000030025.3	Nr4a3	nuclear receptor subfamily 4, group A, member 3
chr1_+_170214826	3.095	ENSMUST00000159201.1 ENSMUST00000055830.1	4930500M09Rik	RIKEN cDNA 4930500M09 gene
chr1_-_130729249	3.090	ENSMUST00000171479.1	Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr5_+_107497762	3.087	ENSMUST00000152474.1 ENSMUST00000060553.7	A830010M20Rik	RIKEN cDNA A830010M20 gene
chr18_+_23803962	3.063	ENSMUST00000025127.3	Mapre2	microtubule-associated protein, RP/EB family, member 2
chr4_-_134245579	3.037	ENSMUST00000030644.7	Zfp593	zinc finger protein 593
chr5_-_97111565	3.008	ENSMUST00000112969.3	Paqr3	progestin and adipoQ receptor family member III
chr13_-_54688065	3.005	ENSMUST00000125871.1	Rnf44	ring finger protein 44
chr5_-_97111589	2.975	ENSMUST00000069453.2 ENSMUST00000112968.1	Paqr3	progestin and adipoQ receptor family member III
chr7_-_98119482	2.948	ENSMUST00000138627.1 ENSMUST00000107127.1 ENSMUST00000107128.1	Myo7a	myosin VIIA
chr5_-_25223153	2.948	ENSMUST00000066954.1	E130116L18Rik	RIKEN cDNA E130116L18 gene
chr8_+_65618009	2.941	ENSMUST00000110258.1 ENSMUST00000110256.1 ENSMUST00000110255.1	March1	membrane-associated ring finger (C3HC4) 1
chr12_+_109540979	2.937	ENSMUST00000129245.1 ENSMUST00000143836.1 ENSMUST00000124106.1	Meg3	maternally expressed 3
chr3_-_117360876	2.932	ENSMUST00000061071.8	D3Bwg0562e	DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr3_-_127409044	2.930	ENSMUST00000182704.1	Ank2	ankyrin 2, brain
chr11_-_59163281	2.924	ENSMUST00000069631.2	Iba57	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr9_+_106170918	2.923	ENSMUST00000020490.5	Wdr82	WD repeat domain containing 82
chr11_-_42000834	2.918	ENSMUST00000070725.4	Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr9_-_96752822	2.858	ENSMUST00000152594.1	Zbtb38	zinc finger and BTB domain containing 38
chr2_-_140671462	2.856	ENSMUST00000110057.2	Flrt3	fibronectin leucine rich transmembrane protein 3
chr14_+_101840602	2.854	ENSMUST00000159314.1	Lmo7	LIM domain only 7
chr6_-_39725193	2.836	ENSMUST00000101497.3	Braf	Braf transforming gene
chr11_+_94044111	2.823	ENSMUST00000132079.1	Spag9	sperm associated antigen 9
chr17_-_27565678	2.792	ENSMUST00000154473.1	AI413582	expressed sequence AI413582
chr5_+_33018816	2.767	ENSMUST00000019109.7	Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr11_-_59163696	2.753	ENSMUST00000137433.1 ENSMUST00000054523.5	Iba57	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr3_-_127408986	2.753	ENSMUST00000182588.1 ENSMUST00000182959.1 ENSMUST00000182452.1	Ank2	ankyrin 2, brain
chr12_+_58211772	2.749	ENSMUST00000110671.2 ENSMUST00000044299.2	Sstr1	somatostatin receptor 1
chr15_+_81936911	2.740	ENSMUST00000135663.1	Csdc2	cold shock domain containing C2, RNA binding
chr15_+_81400132	2.730	ENSMUST00000163754.1 ENSMUST00000041609.4	Xpnpep3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr2_+_65620829	2.727	ENSMUST00000028377.7	Scn2a1	sodium channel, voltage-gated, type II, alpha 1
chr6_+_57703051	2.720	ENSMUST00000151042.1	Lancl2	LanC (bacterial lantibiotic synthetase component C)-like 2
chr8_-_60954726	2.711	ENSMUST00000110302.1	Clcn3	chloride channel 3
chr13_-_100744588	2.700	ENSMUST00000078573.4 ENSMUST00000109333.1	Mrps36	mitochondrial ribosomal protein S36
chr6_+_96113146	2.685	ENSMUST00000122120.1	Fam19a1	family with sequence similarity 19, member A1
chr17_+_37050631	2.682	ENSMUST00000172792.1 ENSMUST00000174347.1	Gabbr1	gamma-aminobutyric acid (GABA) B receptor, 1
chr2_-_130839683	2.675	ENSMUST00000119422.1	4930402H24Rik	RIKEN cDNA 4930402H24 gene
chr17_-_33760451	2.668	ENSMUST00000057373.7	Rab11b	RAB11B, member RAS oncogene family
chr6_-_8778439	2.668	ENSMUST00000115520.1 ENSMUST00000038403.5 ENSMUST00000115518.1	Ica1	islet cell autoantigen 1
chr6_-_8778106	2.641	ENSMUST00000151758.1 ENSMUST00000115519.1 ENSMUST00000153390.1	Ica1	islet cell autoantigen 1
chr12_-_17176888	2.638	ENSMUST00000170580.1	Kcnf1	potassium voltage-gated channel, subfamily F, member 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.4	13.2	GO:0003345	proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
2.5	30.0	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
2.5	7.5	GO:0045204	MAPK export from nucleus(GO:0045204)
2.4	7.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
2.3	6.9	GO:0030070	insulin processing(GO:0030070)
2.2	6.5	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
2.1	18.6	GO:0060373	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
2.1	6.2	GO:0001830	trophectodermal cell fate commitment(GO:0001830)
1.9	17.2	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
1.8	9.0	GO:0051012	microtubule sliding(GO:0051012)
1.8	8.8	GO:0048245	eosinophil chemotaxis(GO:0048245)
1.7	7.0	GO:0045054	constitutive secretory pathway(GO:0045054)
1.7	12.0	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.6	4.9	GO:0097309	cap1 mRNA methylation(GO:0097309)
1.5	13.9	GO:0036371	protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.5	7.6	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
1.5	4.4	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
1.4	6.8	GO:1902412	regulation of mitotic cytokinesis(GO:1902412)
1.3	1.3	GO:0060067	cervix development(GO:0060067)
1.3	6.3	GO:2000551	regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
1.2	3.7	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
1.2	8.4	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
1.1	5.6	GO:0032763	regulation of mast cell cytokine production(GO:0032763)
1.1	2.2	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
1.1	4.3	GO:0097167	circadian regulation of translation(GO:0097167)
1.1	3.2	GO:1900369	negative regulation of RNA interference(GO:1900369)
1.0	4.1	GO:0090467	regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
1.0	4.0	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
1.0	2.9	GO:0060382	regulation of DNA strand elongation(GO:0060382)
1.0	3.9	GO:0051866	general adaptation syndrome(GO:0051866)
0.9	6.4	GO:0033227	dsRNA transport(GO:0033227)
0.9	2.7	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.9	3.5	GO:0044268	multicellular organismal protein metabolic process(GO:0044268)
0.9	7.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.9	15.7	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.8	16.9	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8	9.1	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.8	5.0	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.8	2.5	GO:0032696	negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.8	6.5	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.8	1.6	GO:0035973	aggrephagy(GO:0035973)
0.8	7.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8	2.3	GO:0019085	early viral transcription(GO:0019085)
0.8	2.3	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.8	9.9	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.8	4.5	GO:0007258	JUN phosphorylation(GO:0007258)
0.7	2.2	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.7	4.4	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.7	3.6	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.7	2.2	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.7	8.6	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.7	2.1	GO:0002182	cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.7	4.8	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.7	3.3	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.7	7.8	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.6	1.9	GO:0009182	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.6	13.4	GO:0006198	cAMP catabolic process(GO:0006198)
0.6	5.6	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.6	5.6	GO:0071420	cellular response to histamine(GO:0071420)
0.6	1.8	GO:0031038	myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.6	1.8	GO:0007341	penetration of zona pellucida(GO:0007341)
0.6	4.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.6	2.4	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6	1.8	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) actin filament branching(GO:0090135)
0.6	1.7	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.6	2.3	GO:0003357	noradrenergic neuron differentiation(GO:0003357)
0.6	2.2	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.6	2.2	GO:0018343	protein farnesylation(GO:0018343)
0.6	2.8	GO:0007021	tubulin complex assembly(GO:0007021)
0.6	1.7	GO:0034334	adherens junction maintenance(GO:0034334)
0.6	1.7	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.5	3.3	GO:0098964	dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.5	9.3	GO:0001553	luteinization(GO:0001553)
0.5	0.5	GO:0071677	positive regulation of mononuclear cell migration(GO:0071677)
0.5	11.2	GO:0010763	positive regulation of fibroblast migration(GO:0010763)
0.5	1.0	GO:1901723	negative regulation of cell proliferation involved in kidney development(GO:1901723)
0.5	1.6	GO:2000501	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.5	1.6	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.5	51.2	GO:0031110	regulation of microtubule polymerization or depolymerization(GO:0031110)
0.5	1.5	GO:0019389	urate transport(GO:0015747) glucuronoside metabolic process(GO:0019389) negative regulation of intestinal absorption(GO:1904479)
0.5	1.4	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.5	2.3	GO:0035617	stress granule disassembly(GO:0035617)
0.4	1.3	GO:1903538	meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.4	3.0	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.4	2.6	GO:0060702	negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.4	6.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.4	2.0	GO:0021993	initiation of neural tube closure(GO:0021993)
0.4	4.4	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.4	1.2	GO:0032025	response to cobalt ion(GO:0032025)
0.4	2.0	GO:0060690	epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.4	4.3	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.4	15.5	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.4	0.4	GO:1904672	regulation of somatic stem cell population maintenance(GO:1904672)
0.4	1.9	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.4	1.9	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.4	1.5	GO:0097343	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.4	1.1	GO:0051933	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.4	9.4	GO:0071625	vocalization behavior(GO:0071625)
0.4	1.9	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.4	1.1	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.4	1.1	GO:0061744	motor behavior(GO:0061744)
0.4	1.1	GO:0035574	histone H4-K20 demethylation(GO:0035574)
0.4	1.8	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.4	1.1	GO:0035844	positive regulation of polarized epithelial cell differentiation(GO:0030862) cloaca development(GO:0035844)
0.4	1.1	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.4	29.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.4	3.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.3	1.4	GO:1900533	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3	1.7	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.3	1.4	GO:2000481	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.3	0.7	GO:0043622	cortical microtubule organization(GO:0043622)
0.3	1.0	GO:0090285	negative regulation of protein glycosylation in Golgi(GO:0090285)
0.3	0.7	GO:1903596	regulation of gap junction assembly(GO:1903596)
0.3	4.3	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.3	2.3	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.3	2.9	GO:0050957	equilibrioception(GO:0050957)
0.3	4.9	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.3	1.3	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.3	0.6	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.3	1.6	GO:0090669	telomerase RNA stabilization(GO:0090669)
0.3	2.9	GO:0009644	response to high light intensity(GO:0009644)
0.3	1.6	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.3	2.6	GO:0021830	substrate-independent telencephalic tangential migration(GO:0021826) interneuron migration from the subpallium to the cortex(GO:0021830) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.3	1.0	GO:0021592	fourth ventricle development(GO:0021592) actin filament bundle distribution(GO:0070650)
0.3	3.8	GO:0010818	T cell chemotaxis(GO:0010818)
0.3	1.6	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.3	2.5	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.3	4.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.3	2.8	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.3	3.3	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.3	2.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.3	6.9	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.3	6.8	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.3	1.8	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3	1.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.3	3.1	GO:0023041	neuronal signal transduction(GO:0023041)
0.3	3.4	GO:0002329	pre-B cell differentiation(GO:0002329)
0.3	1.1	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.3	2.0	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.3	3.1	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.3	3.4	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.3	1.4	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.3	0.8	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3	1.3	GO:0045342	MHC class II biosynthetic process(GO:0045342) regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347)
0.3	1.3	GO:0035063	nuclear speck organization(GO:0035063)
0.3	0.8	GO:0039533	regulation of MDA-5 signaling pathway(GO:0039533)
0.2	1.7	GO:0032790	ribosome disassembly(GO:0032790)
0.2	0.7	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2	11.0	GO:0008089	anterograde axonal transport(GO:0008089)
0.2	2.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.2	1.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.2	0.7	GO:0006553	lysine metabolic process(GO:0006553)
0.2	4.0	GO:0006622	protein targeting to lysosome(GO:0006622)
0.2	1.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.2	4.3	GO:0034389	lipid particle organization(GO:0034389)
0.2	0.7	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.2	0.7	GO:0006669	sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2	1.4	GO:0009235	cobalamin metabolic process(GO:0009235)
0.2	5.8	GO:0001706	endoderm formation(GO:0001706)
0.2	3.6	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.2	5.3	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.2	2.6	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.2	1.9	GO:0046541	saliva secretion(GO:0046541)
0.2	0.4	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.2	1.0	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.2	3.3	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2	0.6	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.2	0.4	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.2	2.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.2	2.2	GO:0043084	penile erection(GO:0043084)
0.2	0.6	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2	1.2	GO:0070294	renal sodium ion absorption(GO:0070294)
0.2	0.6	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.2	1.3	GO:0051004	plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004)
0.2	0.8	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.2	4.2	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2	1.5	GO:2001054	negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.2	1.3	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.2	2.6	GO:0000012	single strand break repair(GO:0000012)
0.2	0.2	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.2	1.7	GO:0007000	nucleolus organization(GO:0007000)
0.2	2.7	GO:0003094	glomerular filtration(GO:0003094)
0.2	0.9	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2	3.9	GO:0002931	response to ischemia(GO:0002931)
0.2	1.2	GO:0035902	response to immobilization stress(GO:0035902)
0.2	2.1	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.2	0.5	GO:2000850	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.2	0.4	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.2	1.4	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.2	1.4	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.2	2.9	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2	3.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2	0.3	GO:0002035	brain renin-angiotensin system(GO:0002035)
0.2	1.2	GO:0015670	carbon dioxide transport(GO:0015670)
0.2	1.2	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.2	1.1	GO:0032782	bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2	0.8	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2	5.2	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.2	0.5	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.2	0.9	GO:0099563	modification of synaptic structure(GO:0099563)
0.2	0.5	GO:0043696	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2	0.3	GO:0090399	replicative senescence(GO:0090399)
0.1	0.9	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.1	4.8	GO:0008542	visual learning(GO:0008542)
0.1	2.2	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.1	0.9	GO:2001204	neutrophil activation involved in immune response(GO:0002283) regulation of osteoclast development(GO:2001204)
0.1	2.5	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.1	0.7	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.1	1.5	GO:0030953	astral microtubule organization(GO:0030953)
0.1	4.3	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.1	1.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.1	1.7	GO:0030813	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1	0.5	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.1	2.6	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.1	1.7	GO:0072395	signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.1	0.4	GO:0090370	negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375) negative regulation of cholesterol efflux(GO:0090370)
0.1	1.0	GO:0080184	response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.1	0.5	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.1	1.5	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	1.0	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.4	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.7	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	0.7	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.8	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	0.1	GO:0021612	facial nerve structural organization(GO:0021612)
0.1	7.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.1	1.8	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	0.9	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1	1.1	GO:0051231	mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.1	0.5	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	0.4	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1	1.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.1	0.8	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.3	GO:0051030	snRNA transport(GO:0051030)
0.1	1.4	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.1	0.6	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1	2.7	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.1	0.6	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1	5.9	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.4	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1	1.1	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	5.6	GO:0007613	memory(GO:0007613)
0.1	0.2	GO:0014060	regulation of epinephrine secretion(GO:0014060)
0.1	0.4	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.8	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566)
0.1	3.3	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.1	0.5	GO:0006983	ER overload response(GO:0006983)
0.1	2.4	GO:0050919	negative chemotaxis(GO:0050919)
0.1	1.3	GO:0035036	binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.1	2.4	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.1	0.2	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1	1.3	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.1	0.5	GO:0003418	growth plate cartilage chondrocyte differentiation(GO:0003418) growth plate cartilage chondrocyte proliferation(GO:0003419) negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1	0.4	GO:0007632	visual behavior(GO:0007632)
0.1	3.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1	0.4	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.9	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.1	6.1	GO:0015758	glucose transport(GO:0015758)
0.1	1.8	GO:0034063	stress granule assembly(GO:0034063)
0.1	10.1	GO:0071805	potassium ion transmembrane transport(GO:0071805)
0.1	4.1	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.1	2.5	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.1	0.5	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1	0.5	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.8	GO:0014823	response to activity(GO:0014823)
0.1	0.1	GO:0036509	trimming of terminal mannose on B branch(GO:0036509) endoplasmic reticulum mannose trimming(GO:1904380)
0.1	0.4	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) embryonic skeletal joint development(GO:0072498)
0.1	1.1	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.1	0.2	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	3.8	GO:0021549	cerebellum development(GO:0021549)
0.1	0.7	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.1	4.7	GO:0007030	Golgi organization(GO:0007030)
0.1	1.3	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1	0.4	GO:0002051	mesodermal cell fate commitment(GO:0001710) osteoblast fate commitment(GO:0002051)
0.0	0.6	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.4	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.0	GO:0002374	cytokine secretion involved in immune response(GO:0002374) regulation of cytokine secretion involved in immune response(GO:0002739) positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0	0.2	GO:0034242	macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.5	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
0.0	3.2	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	1.9	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	5.2	GO:0006457	protein folding(GO:0006457)
0.0	0.4	GO:0086004	regulation of cardiac muscle cell contraction(GO:0086004)
0.0	0.3	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	25.2	GO:0016567	protein ubiquitination(GO:0016567)
0.0	0.8	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0	2.9	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0	0.4	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.7	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.4	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.5	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	1.3	GO:0050729	positive regulation of inflammatory response(GO:0050729)
0.0	0.3	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.2	GO:0060449	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) bud elongation involved in lung branching(GO:0060449)
0.0	0.9	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	1.0	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	1.0	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.4	GO:0051560	mitochondrial calcium ion homeostasis(GO:0051560)
0.0	0.4	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.5	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	1.3	GO:0072583	clathrin-mediated endocytosis(GO:0072583)
0.0	0.5	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	1.0	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	1.3	GO:0048675	axon extension(GO:0048675)
0.0	4.0	GO:0006869	lipid transport(GO:0006869)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.7	GO:0008654	phospholipid biosynthetic process(GO:0008654)
0.0	0.5	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.4	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.6	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	1.1	GO:0030308	negative regulation of cell growth(GO:0030308)
0.0	0.2	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0	0.2	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.2	GO:0003073	regulation of systemic arterial blood pressure(GO:0003073)
0.0	0.2	GO:0009268	response to pH(GO:0009268)
0.0	0.4	GO:0006611	protein export from nucleus(GO:0006611)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	6.5	GO:0005577	fibrinogen complex(GO:0005577)
1.9	1.9	GO:0097447	dendritic tree(GO:0097447)
1.7	8.4	GO:0032437	cuticular plate(GO:0032437)
1.7	24.8	GO:0044754	autolysosome(GO:0044754)
1.6	4.9	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
1.4	5.6	GO:0031673	H zone(GO:0031673)
1.2	7.5	GO:0000235	astral microtubule(GO:0000235)
1.2	18.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
1.2	3.6	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
1.1	3.2	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.0	6.3	GO:0045179	apical cortex(GO:0045179)
0.9	24.1	GO:0031430	M band(GO:0031430)
0.8	5.8	GO:0000322	storage vacuole(GO:0000322)
0.8	2.3	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.7	2.2	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.7	2.7	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.6	2.5	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.6	4.0	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.5	2.7	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5	3.2	GO:0044530	supraspliceosomal complex(GO:0044530)
0.5	4.2	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.5	18.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.5	2.8	GO:0002139	stereocilia coupling link(GO:0002139)
0.5	18.4	GO:0030131	clathrin adaptor complex(GO:0030131)
0.4	2.9	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.4	7.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.4	5.6	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4	4.4	GO:0042581	specific granule(GO:0042581)
0.4	7.2	GO:0000421	autophagosome membrane(GO:0000421)
0.4	4.6	GO:0008385	IkappaB kinase complex(GO:0008385)
0.4	3.2	GO:0045252	dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.3	2.4	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3	1.4	GO:1990415	Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.3	1.7	GO:0001533	cornified envelope(GO:0001533)
0.3	5.3	GO:0043196	varicosity(GO:0043196)
0.3	4.6	GO:0072546	ER membrane protein complex(GO:0072546)
0.3	5.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.3	2.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3	15.5	GO:0005776	autophagosome(GO:0005776)
0.3	3.0	GO:0001739	sex chromatin(GO:0001739)
0.3	0.6	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3	2.1	GO:0070187	telosome(GO:0070187)
0.3	106.6	GO:0014069	postsynaptic density(GO:0014069)
0.3	3.6	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3	3.4	GO:0044232	organelle membrane contact site(GO:0044232)
0.3	0.8	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.3	1.1	GO:1902636	kinociliary basal body(GO:1902636)
0.3	5.6	GO:0035253	ciliary rootlet(GO:0035253)
0.3	1.5	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2	1.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.2	2.3	GO:0032426	stereocilium tip(GO:0032426)
0.2	2.8	GO:0000974	Prp19 complex(GO:0000974)
0.2	2.7	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.2	1.3	GO:0070847	core mediator complex(GO:0070847)
0.2	1.7	GO:0071437	invadopodium(GO:0071437)
0.2	5.9	GO:0060076	excitatory synapse(GO:0060076)
0.2	4.1	GO:0048786	presynaptic active zone(GO:0048786)
0.2	13.1	GO:0031594	neuromuscular junction(GO:0031594)
0.2	0.8	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.2	1.4	GO:0042382	paraspeckles(GO:0042382)
0.2	5.3	GO:0035371	microtubule plus-end(GO:0035371)
0.2	3.6	GO:0030118	clathrin coat(GO:0030118)
0.2	2.1	GO:0043235	receptor complex(GO:0043235)
0.2	1.8	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.2	0.2	GO:0098842	postsynaptic early endosome(GO:0098842)
0.2	1.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	1.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.7	GO:0033263	CORVET complex(GO:0033263)
0.1	2.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	3.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	9.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	3.3	GO:0071565	nBAF complex(GO:0071565)
0.1	1.3	GO:0035102	PRC1 complex(GO:0035102)
0.1	1.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.1	7.1	GO:0030667	secretory granule membrane(GO:0030667)
0.1	6.0	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	1.5	GO:0097542	ciliary tip(GO:0097542)
0.1	1.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.5	GO:0045098	type III intermediate filament(GO:0045098)
0.1	1.3	GO:0005869	dynactin complex(GO:0005869)
0.1	2.0	GO:0097228	sperm principal piece(GO:0097228)
0.1	0.7	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	18.1	GO:0030141	secretory granule(GO:0030141)
0.1	1.4	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	1.8	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1	3.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	0.3	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1	1.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	6.6	GO:0043204	perikaryon(GO:0043204)
0.1	14.8	GO:0001650	fibrillar center(GO:0001650)
0.1	1.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	6.9	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	0.7	GO:0097225	sperm midpiece(GO:0097225)
0.1	0.7	GO:0009925	basal plasma membrane(GO:0009925)
0.1	5.9	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	1.3	GO:0042788	polysomal ribosome(GO:0042788)
0.1	1.4	GO:0032039	integrator complex(GO:0032039)
0.1	5.6	GO:0043679	axon terminus(GO:0043679)
0.1	0.8	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	0.2	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.1	2.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.8	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	3.5	GO:0032587	ruffle membrane(GO:0032587)
0.1	7.6	GO:0008021	synaptic vesicle(GO:0008021)
0.1	2.1	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	2.5	GO:0031902	late endosome membrane(GO:0031902)
0.1	1.9	GO:0044291	cell-cell contact zone(GO:0044291)
0.1	11.9	GO:0016324	apical plasma membrane(GO:0016324)
0.1	1.1	GO:0036038	MKS complex(GO:0036038)
0.1	1.1	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1	7.3	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1	3.1	GO:0005801	cis-Golgi network(GO:0005801)
0.1	3.4	GO:0016328	lateral plasma membrane(GO:0016328)
0.1	0.5	GO:0005677	chromatin silencing complex(GO:0005677)
0.1	0.5	GO:0000439	core TFIIH complex(GO:0000439)
0.1	1.8	GO:0015030	Cajal body(GO:0015030)
0.1	2.5	GO:0045171	intercellular bridge(GO:0045171)
0.1	0.4	GO:0030673	axolemma(GO:0030673)
0.1	0.8	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.6	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.5	GO:0043198	dendritic shaft(GO:0043198)
0.1	1.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.4	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	3.3	GO:0072562	blood microparticle(GO:0072562)
0.0	1.9	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	1.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	1.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	2.0	GO:0043197	dendritic spine(GO:0043197)
0.0	47.7	GO:0005794	Golgi apparatus(GO:0005794)
0.0	3.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	2.7	GO:0000502	proteasome complex(GO:0000502)
0.0	0.5	GO:0005605	basal lamina(GO:0005605)
0.0	0.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.8	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.4	GO:0044433	cytoplasmic vesicle part(GO:0044433)
0.0	4.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	2.3	GO:0030425	dendrite(GO:0030425)
0.0	0.5	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	1.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	1.4	GO:0005581	collagen trimer(GO:0005581)
0.0	1.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	1.7	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.0	3.5	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	3.9	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	2.4	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	1.6	GO:0005769	early endosome(GO:0005769)
0.0	0.5	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.6	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	26.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
2.7	18.6	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
2.4	7.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
1.9	5.8	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
1.6	6.4	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.4	13.9	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.3	5.3	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.3	3.9	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
1.2	3.7	GO:0002153	steroid receptor RNA activator RNA binding(GO:0002153)
1.2	4.9	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
1.2	4.8	GO:0005093	Rab GDP-dissociation inhibitor activity(GO:0005093)
1.2	3.5	GO:0003989	acetyl-CoA carboxylase activity(GO:0003989)
1.1	3.4	GO:0097677	STAT family protein binding(GO:0097677)
1.1	4.5	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.1	9.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
1.1	4.4	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
1.1	3.3	GO:0034190	apolipoprotein receptor binding(GO:0034190)
1.1	6.5	GO:0045340	mercury ion binding(GO:0045340)
1.1	3.2	GO:0003692	left-handed Z-DNA binding(GO:0003692)
1.0	3.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
1.0	2.9	GO:1990955	G-rich single-stranded DNA binding(GO:1990955)
0.9	6.6	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.9	3.6	GO:0035473	lipase binding(GO:0035473)
0.9	11.4	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.9	2.6	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.9	6.9	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.8	13.2	GO:0045499	chemorepellent activity(GO:0045499)
0.8	8.6	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.7	2.2	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.7	7.8	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.7	4.9	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.7	4.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.7	5.3	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.6	1.9	GO:0044715	8-oxo-dGDP phosphatase activity(GO:0044715)
0.6	3.2	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.6	1.3	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.6	4.9	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.6	9.0	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.6	4.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.6	13.9	GO:0031489	myosin V binding(GO:0031489)
0.6	1.7	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.6	1.7	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.6	6.8	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.6	5.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.5	18.0	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.5	11.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.5	10.6	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.5	8.7	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.5	9.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.5	2.8	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.4	1.3	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.4	2.7	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.4	2.2	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.4	1.8	GO:0048495	Roundabout binding(GO:0048495)
0.4	2.6	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.4	1.7	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.4	2.5	GO:0051429	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4	9.1	GO:0042056	chemoattractant activity(GO:0042056)
0.4	1.2	GO:0000992	polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.4	10.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.4	2.0	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4	3.9	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.4	1.2	GO:0030507	spectrin binding(GO:0030507)
0.4	2.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4	1.2	GO:0004458	D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.4	3.4	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.4	1.1	GO:0035575	histone demethylase activity (H4-K20 specific)(GO:0035575)
0.4	1.8	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.3	8.4	GO:0030506	ankyrin binding(GO:0030506)
0.3	1.7	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3	1.0	GO:0071633	dihydroceramidase activity(GO:0071633)
0.3	1.6	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3	2.5	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.3	20.8	GO:0015459	potassium channel regulator activity(GO:0015459)
0.3	2.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.3	5.0	GO:0030957	Tat protein binding(GO:0030957)
0.3	5.6	GO:0004890	GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.3	1.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.3	1.5	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.3	1.4	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.3	3.9	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	2.0	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3	5.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.3	2.9	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.3	3.6	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	7.0	GO:0003785	actin monomer binding(GO:0003785)
0.2	1.4	GO:0004043	L-aminoadipate-semialdehyde dehydrogenase activity(GO:0004043)
0.2	17.2	GO:0030276	clathrin binding(GO:0030276)
0.2	2.4	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	0.7	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.2	1.5	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.2	1.9	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2	1.7	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.2	4.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	2.7	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2	0.8	GO:0047389	glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2	2.5	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.2	5.9	GO:0008146	sulfotransferase activity(GO:0008146)
0.2	1.3	GO:0032564	dATP binding(GO:0032564)
0.2	1.3	GO:0031419	cobalamin binding(GO:0031419)
0.2	2.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2	3.7	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	7.6	GO:0042169	SH2 domain binding(GO:0042169)
0.2	58.8	GO:0015631	tubulin binding(GO:0015631)
0.2	1.5	GO:0036122	BMP binding(GO:0036122)
0.2	11.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.2	0.7	GO:0070573	tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.2	0.8	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.2	5.3	GO:0050699	WW domain binding(GO:0050699)
0.2	2.1	GO:0019215	intermediate filament binding(GO:0019215)
0.2	3.0	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2	0.2	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
0.2	5.4	GO:0005112	Notch binding(GO:0005112)
0.2	2.9	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2	1.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.2	42.3	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.1	0.6	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	9.4	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.1	14.8	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	3.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.8	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.1	1.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	4.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	2.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.7	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	1.2	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.1	0.2	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1	1.8	GO:0005537	mannose binding(GO:0005537)
0.1	2.8	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	2.8	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.1	1.7	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.6	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	1.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.6	GO:1990715	mRNA CDS binding(GO:1990715)
0.1	2.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.1	2.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	1.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	4.7	GO:0070888	E-box binding(GO:0070888)
0.1	2.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.1	7.7	GO:0051082	unfolded protein binding(GO:0051082)
0.1	6.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	12.0	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	6.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	8.7	GO:0043130	ubiquitin binding(GO:0043130)
0.1	0.4	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.5	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.4	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.1	4.0	GO:0015485	cholesterol binding(GO:0015485)
0.1	2.6	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	2.1	GO:0042805	actinin binding(GO:0042805)
0.1	1.3	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	4.5	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	0.2	GO:0046969	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1	0.9	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1	30.2	GO:0005509	calcium ion binding(GO:0005509)
0.1	0.8	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.4	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.4	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.1	4.7	GO:0051213	dioxygenase activity(GO:0051213)
0.1	2.7	GO:0004177	aminopeptidase activity(GO:0004177)
0.1	0.9	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.4	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	0.9	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.1	3.0	GO:0043621	protein self-association(GO:0043621)
0.1	1.7	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	3.1	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	0.4	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	1.9	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	0.2	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
0.1	0.5	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	1.9	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1	1.5	GO:0008009	chemokine activity(GO:0008009)
0.0	1.2	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.8	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	2.4	GO:0019955	cytokine binding(GO:0019955)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.5	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.3	GO:0098505	single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	1.1	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	13.9	GO:0008289	lipid binding(GO:0008289)
0.0	0.7	GO:0042171	lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0	2.7	GO:0008135	translation factor activity, RNA binding(GO:0008135)
0.0	0.5	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.7	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	1.7	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.6	GO:0044325	ion channel binding(GO:0044325)
0.0	0.9	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.4	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.8	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.6	GO:0002020	protease binding(GO:0002020)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.5	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	4.2	PID_ATF2_PATHWAY	ATF-2 transcription factor network
0.4	20.0	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	Genes related to regulation of the actin cytoskeleton
0.4	10.9	PID_INTEGRIN_A9B1_PATHWAY	Alpha9 beta1 integrin signaling events
0.3	9.7	PID_INSULIN_GLUCOSE_PATHWAY	Insulin-mediated glucose transport
0.3	1.1	ST_IL_13_PATHWAY	Interleukin 13 (IL-13) Pathway
0.3	10.0	PID_LIS1_PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.3	5.1	ST_G_ALPHA_S_PATHWAY	G alpha s Pathway
0.2	16.4	PID_ERBB1_INTERNALIZATION_PATHWAY	Internalization of ErbB1
0.2	5.0	PID_S1P_META_PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.2	6.9	ST_ERK1_ERK2_MAPK_PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	10.4	SIG_CD40PATHWAYMAP	Genes related to CD40 signaling
0.2	2.8	PID_KIT_PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2	1.6	PID_CXCR4_PATHWAY	CXCR4-mediated signaling events
0.2	5.1	PID_HDAC_CLASSIII_PATHWAY	Signaling events mediated by HDAC Class III
0.2	3.1	ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY	PI3K Pathway
0.2	3.0	PID_CIRCADIAN_PATHWAY	Circadian rhythm pathway
0.2	5.3	NABA_PROTEOGLYCANS	Genes encoding proteoglycans
0.2	3.0	PID_NFKAPPAB_CANONICAL_PATHWAY	Canonical NF-kappaB pathway
0.1	1.6	PID_ARF6_DOWNSTREAM_PATHWAY	Arf6 downstream pathway
0.1	6.7	PID_TAP63_PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	3.2	ST_GA13_PATHWAY	G alpha 13 Pathway
0.1	9.4	PID_TGFBR_PATHWAY	TGF-beta receptor signaling
0.1	1.0	PID_TCR_CALCIUM_PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	3.9	PID_PI3KCI_PATHWAY	Class I PI3K signaling events
0.1	2.6	PID_DNA_PK_PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	5.4	PID_ARF6_TRAFFICKING_PATHWAY	Arf6 trafficking events
0.1	7.6	PID_RAC1_REG_PATHWAY	Regulation of RAC1 activity
0.1	0.7	SA_MMP_CYTOKINE_CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	1.7	PID_SYNDECAN_2_PATHWAY	Syndecan-2-mediated signaling events
0.1	2.6	PID_ARF_3PATHWAY	Arf1 pathway
0.1	5.9	PID_LKB1_PATHWAY	LKB1 signaling events
0.1	0.5	PID_IL5_PATHWAY	IL5-mediated signaling events
0.1	1.3	PID_IL8_CXCR2_PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	1.2	PID_ERB_GENOMIC_PATHWAY	Validated nuclear estrogen receptor beta network
0.1	0.9	PID_ER_NONGENOMIC_PATHWAY	Plasma membrane estrogen receptor signaling
0.1	2.6	PID_IL4_2PATHWAY	IL4-mediated signaling events
0.1	2.0	PID_INTEGRIN_A4B1_PATHWAY	Alpha4 beta1 integrin signaling events
0.1	1.7	SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.1	1.5	PID_BETA_CATENIN_DEG_PATHWAY	Degradation of beta catenin
0.1	1.6	PID_HIV_NEF_PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	0.4	SA_CASPASE_CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	1.0	PID_RHOA_PATHWAY	RhoA signaling pathway
0.1	1.9	PID_INTEGRIN1_PATHWAY	Beta1 integrin cell surface interactions
0.1	1.9	PID_NFAT_3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.1	PID_MAPK_TRK_PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	1.3	PID_SHP2_PATHWAY	SHP2 signaling
0.1	0.4	PID_ALK2_PATHWAY	ALK2 signaling events
0.0	0.7	PID_TRKR_PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.6	PID_P75_NTR_PATHWAY	p75(NTR)-mediated signaling
0.0	0.4	PID_EPHA_FWDPATHWAY	EPHA forward signaling
0.0	0.3	PID_NECTIN_PATHWAY	Nectin adhesion pathway
0.0	1.1	WNT_SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.6	PID_NCADHERIN_PATHWAY	N-cadherin signaling events
0.0	0.4	PID_AR_TF_PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID_P38_ALPHA_BETA_PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.1	PID_INTEGRIN2_PATHWAY	Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	26.0	REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING	Genes involved in Retrograde neurotrophin signalling
1.0	36.0	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.8	5.9	REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.5	4.8	REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.5	7.6	REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.4	5.3	REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4	5.7	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.4	10.5	REACTOME_CGMP_EFFECTS	Genes involved in cGMP effects
0.4	0.7	REACTOME_ADP_SIGNALLING_THROUGH_P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.3	5.6	REACTOME_GABA_A_RECEPTOR_ACTIVATION	Genes involved in GABA A receptor activation
0.3	0.7	REACTOME_SHC_MEDIATED_SIGNALLING	Genes involved in SHC-mediated signalling
0.3	5.4	REACTOME_ACTIVATION_OF_RAC	Genes involved in Activation of Rac
0.3	7.1	REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING	Genes involved in Insulin Synthesis and Processing
0.3	13.4	REACTOME_DARPP_32_EVENTS	Genes involved in DARPP-32 events
0.3	11.2	REACTOME_HS_GAG_BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.3	2.4	REACTOME_GAP_JUNCTION_DEGRADATION	Genes involved in Gap junction degradation
0.3	6.1	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	3.2	REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	5.3	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	1.3	REACTOME_ERKS_ARE_INACTIVATED	Genes involved in ERKs are inactivated
0.2	2.7	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2	1.8	REACTOME_CD28_DEPENDENT_VAV1_PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.2	4.5	REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2	3.9	REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN	Genes involved in Signalling to p38 via RIT and RIN
0.2	6.9	REACTOME_G_PROTEIN_ACTIVATION	Genes involved in G-protein activation
0.2	2.0	REACTOME_PLATELET_SENSITIZATION_BY_LDL	Genes involved in Platelet sensitization by LDL
0.2	5.4	REACTOME_IL_RECEPTOR_SHC_SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	3.6	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.2	2.6	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	6.2	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.8	REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	3.1	REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	1.2	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	Genes involved in Transport of organic anions
0.1	1.5	REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	10.7	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	Genes involved in NRAGE signals death through JNK
0.1	3.0	REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.4	REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	1.4	REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1	1.6	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.1	2.2	REACTOME_INSULIN_RECEPTOR_RECYCLING	Genes involved in Insulin receptor recycling
0.1	0.9	REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	3.5	REACTOME_GLYCOLYSIS	Genes involved in Glycolysis
0.1	0.9	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	3.4	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.6	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.8	REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	2.4	REACTOME_SIGNALING_BY_HIPPO	Genes involved in Signaling by Hippo
0.1	1.3	REACTOME_NOD1_2_SIGNALING_PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	8.3	REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.1	2.6	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	0.7	REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	1.6	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.3	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	4.4	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	1.1	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	0.8	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	2.1	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.8	REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	1.2	REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	0.7	REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.6	REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	1.6	REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.4	REACTOME_GAP_JUNCTION_TRAFFICKING	Genes involved in Gap junction trafficking
0.0	2.2	REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.4	REACTOME_IL_3_5_AND_GM_CSF_SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.8	REACTOME_METABOLISM_OF_PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	3.4	REACTOME_SIGNALING_BY_RHO_GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.4	REACTOME_CIRCADIAN_CLOCK	Genes involved in Circadian Clock
0.0	1.4	REACTOME_NCAM1_INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.8	REACTOME_DEADENYLATION_OF_MRNA	Genes involved in Deadenylation of mRNA
0.0	1.3	REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.7	REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.3	REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.3	REACTOME_EGFR_DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.6	REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME_SIGNALING_BY_BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME_CALNEXIN_CALRETICULIN_CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.6	REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)