Motif ID: Klf8

Z-value: 1.035


Transcription factors associated with Klf8:

Gene SymbolEntrez IDGene Name
Klf8 ENSMUSG00000041649.7 Klf8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf8mm10_v2_chrX_+_153237748_153237748-0.491.7e-04Click!


Activity profile for motif Klf8.

activity profile for motif Klf8


Sorted Z-values histogram for motif Klf8

Sorted Z-values for motif Klf8



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_70851189 14.731 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr6_-_72788952 12.711 ENSMUST00000114053.2
Tcf7l1
transcription factor 7 like 1 (T cell specific, HMG box)
chr9_-_8004585 9.664 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr2_-_36105271 8.994 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr13_-_60177357 8.724 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr18_-_74961252 8.092 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr7_+_4119525 7.516 ENSMUST00000119661.1
ENSMUST00000129423.1
Ttyh1

tweety homolog 1 (Drosophila)

chr7_+_4119556 7.510 ENSMUST00000079415.5
Ttyh1
tweety homolog 1 (Drosophila)
chr14_-_103843685 7.501 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr7_-_127026479 7.406 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr4_+_46450892 7.220 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_172550991 7.171 ENSMUST00000170744.1
Tfap2c
transcription factor AP-2, gamma
chr1_-_20820213 6.678 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr18_-_78206408 6.409 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr13_+_48261427 5.665 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr1_+_172499948 5.602 ENSMUST00000111230.1
Tagln2
transgelin 2
chr7_-_144939823 5.521 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr19_+_25610533 5.376 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr10_+_4710119 5.325 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr7_+_144838590 4.236 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr4_-_97778042 4.222 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_-_30973464 3.961 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chrX_+_96096034 3.932 ENSMUST00000117399.1
Msn
moesin
chr3_+_87948666 3.897 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr12_-_69228167 3.891 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr5_-_114690974 3.863 ENSMUST00000012028.7
Gltp
glycolipid transfer protein
chr11_-_32222233 3.579 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr3_+_94377432 3.522 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr15_+_78926720 3.396 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr3_+_146500071 3.393 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr3_+_146499828 3.284 ENSMUST00000090031.5
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr14_+_65358661 3.190 ENSMUST00000066994.6
Zfp395
zinc finger protein 395
chr17_-_70851710 3.185 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr15_-_75909543 3.171 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr11_-_109473220 3.143 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr3_+_94377505 3.104 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr3_+_146499850 3.066 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr2_+_156840077 3.018 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr16_-_18811615 3.014 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr15_+_39006272 2.997 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr2_-_156839790 2.933 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr12_+_53248677 2.928 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr14_-_8666236 2.907 ENSMUST00000102996.3
4930452B06Rik
RIKEN cDNA 4930452B06 gene
chrX_+_71050160 2.895 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr2_+_109280738 2.783 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr1_+_92831614 2.779 ENSMUST00000045970.6
Gpc1
glypican 1
chr2_+_27886416 2.753 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr3_-_89393294 2.703 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr11_+_69632927 2.645 ENSMUST00000018909.3
Fxr2
fragile X mental retardation, autosomal homolog 2
chr1_-_75505641 2.634 ENSMUST00000155084.1
Obsl1
obscurin-like 1
chrX_-_51205990 2.582 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr10_-_80399478 2.563 ENSMUST00000092295.3
ENSMUST00000105349.1
Mbd3

methyl-CpG binding domain protein 3

chr1_+_191098414 2.559 ENSMUST00000027943.4
Batf3
basic leucine zipper transcription factor, ATF-like 3
chr9_+_66158206 2.521 ENSMUST00000034944.2
Dapk2
death-associated protein kinase 2
chr13_-_3918157 2.518 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr11_-_82871133 2.496 ENSMUST00000071152.7
ENSMUST00000108173.3
Rffl

ring finger and FYVE like domain containing protein

chr7_+_126847908 2.477 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr7_-_93081027 2.419 ENSMUST00000098303.1
Gm9934
predicted gene 9934
chr7_+_112427706 2.404 ENSMUST00000033030.7
Parva
parvin, alpha
chr19_+_5740885 2.394 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr18_+_60925612 2.355 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr10_-_13388753 2.310 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr10_-_58675631 2.224 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr19_-_12765447 2.220 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr2_-_165473187 2.211 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr5_+_139423151 2.183 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr17_+_34898931 2.139 ENSMUST00000097342.3
ENSMUST00000013931.5
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr3_+_87906321 2.138 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr10_-_13388830 2.095 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr7_-_100656953 2.063 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr10_-_5805412 2.053 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr10_-_77089428 1.980 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr7_+_16843049 1.976 ENSMUST00000086104.4
Prkd2
protein kinase D2
chr15_-_89355655 1.944 ENSMUST00000023283.5
Lmf2
lipase maturation factor 2
chr13_+_49187485 1.924 ENSMUST00000049022.8
ENSMUST00000120733.1
Ninj1

ninjurin 1

chr12_+_8771405 1.922 ENSMUST00000171158.1
Sdc1
syndecan 1
chr7_+_73391160 1.915 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr11_-_5261558 1.913 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr6_+_85187438 1.910 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chrM_-_14060 1.909 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr19_-_4615453 1.892 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr19_+_7268296 1.869 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr15_-_75909289 1.806 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr3_+_121723515 1.793 ENSMUST00000029771.8
F3
coagulation factor III
chr15_-_75909319 1.790 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr7_-_63938862 1.781 ENSMUST00000063694.8
Klf13
Kruppel-like factor 13
chr17_+_86963077 1.780 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr7_+_16842896 1.771 ENSMUST00000168093.2
Prkd2
protein kinase D2
chr11_-_69948145 1.724 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr11_-_70656467 1.713 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr3_+_90541146 1.656 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr4_-_135873801 1.613 ENSMUST00000030436.5
Pnrc2
proline-rich nuclear receptor coactivator 2
chr19_+_6975048 1.605 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_24696147 1.574 ENSMUST00000046839.8
Gfer
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr12_+_8771317 1.567 ENSMUST00000020911.7
Sdc1
syndecan 1
chr2_-_54085542 1.537 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr7_-_139582790 1.527 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr8_-_87959560 1.516 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr1_-_106714217 1.496 ENSMUST00000112751.1
Bcl2
B cell leukemia/lymphoma 2
chr15_+_99702278 1.446 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr12_+_84009481 1.445 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr11_+_60537978 1.436 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr17_+_34898463 1.430 ENSMUST00000114033.2
ENSMUST00000078061.6
Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr11_-_102407455 1.396 ENSMUST00000107098.1
ENSMUST00000018821.2
Slc25a39

solute carrier family 25, member 39

chr4_+_41762309 1.391 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr18_+_60925644 1.389 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr17_-_25868727 1.388 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr10_-_13193096 1.388 ENSMUST00000019950.4
Ltv1
LTV1 homolog (S. cerevisiae)
chr11_+_114765363 1.384 ENSMUST00000138804.1
ENSMUST00000084368.5
Kif19a

kinesin family member 19A

chr19_+_46305682 1.380 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr15_+_89355730 1.380 ENSMUST00000074552.5
ENSMUST00000088717.6
Ncaph2

non-SMC condensin II complex, subunit H2

chr4_+_148160613 1.372 ENSMUST00000047951.8
Fbxo2
F-box protein 2
chr11_-_109472611 1.371 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr9_-_106158109 1.364 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr10_+_94514825 1.361 ENSMUST00000065060.5
Tmcc3
transmembrane and coiled coil domains 3
chr16_+_64851991 1.355 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr11_+_70657196 1.350 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chr6_+_120666388 1.326 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr1_-_172027269 1.314 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr10_+_96616998 1.312 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr8_-_70659645 1.311 ENSMUST00000070173.7
Pgpep1
pyroglutamyl-peptidase I
chrX_-_73921917 1.309 ENSMUST00000114389.3
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr15_+_89355716 1.304 ENSMUST00000036987.5
Ncaph2
non-SMC condensin II complex, subunit H2
chr11_-_102407315 1.288 ENSMUST00000149777.1
ENSMUST00000154001.1
Slc25a39

solute carrier family 25, member 39

chr4_-_57956283 1.285 ENSMUST00000030051.5
Txn1
thioredoxin 1
chr14_+_55854115 1.248 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr13_-_29984219 1.205 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr18_+_74442500 1.201 ENSMUST00000074157.6
Myo5b
myosin VB
chr9_-_82975475 1.197 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr2_-_168590315 1.187 ENSMUST00000109184.1
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr11_+_70657687 1.178 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr2_+_32535315 1.157 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chr5_-_52566264 1.141 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr8_+_105170668 1.137 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr17_-_46705002 1.095 ENSMUST00000002839.8
Ppp2r5d
protein phosphatase 2, regulatory subunit B (B56), delta isoform
chr1_-_82291370 1.069 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chrX_-_51205773 1.068 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr11_-_69579320 1.062 ENSMUST00000048139.5
Wrap53
WD repeat containing, antisense to Trp53
chr17_+_46646225 1.048 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chrX_-_73921828 1.039 ENSMUST00000096316.3
ENSMUST00000114390.1
ENSMUST00000114391.3
ENSMUST00000114387.1
Naa10



N(alpha)-acetyltransferase 10, NatA catalytic subunit



chr14_+_122534305 1.036 ENSMUST00000154206.1
ENSMUST00000038374.6
ENSMUST00000135578.1
Pcca


propionyl-Coenzyme A carboxylase, alpha polypeptide


chr2_+_27709247 1.025 ENSMUST00000100251.2
Rxra
retinoid X receptor alpha
chr7_-_31055594 1.022 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr7_-_19399859 1.008 ENSMUST00000047170.3
ENSMUST00000108459.2
Klc3

kinesin light chain 3

chrX_-_73921930 1.008 ENSMUST00000033763.8
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr11_+_108920800 1.001 ENSMUST00000140821.1
Axin2
axin2
chr19_-_4615647 0.998 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr4_-_136602641 0.994 ENSMUST00000105847.1
ENSMUST00000116273.2
Kdm1a

lysine (K)-specific demethylase 1A

chr12_+_71016658 0.986 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr16_+_93683184 0.963 ENSMUST00000039620.6
Cbr3
carbonyl reductase 3
chr7_+_30565410 0.963 ENSMUST00000043850.7
Igflr1
IGF-like family receptor 1
chr15_-_36608959 0.939 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr4_-_57143437 0.935 ENSMUST00000095076.3
ENSMUST00000030142.3
Epb4.1l4b

erythrocyte protein band 4.1-like 4b

chr2_-_30093642 0.915 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr2_+_30416031 0.899 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr3_+_129213920 0.897 ENSMUST00000042587.10
Pitx2
paired-like homeodomain transcription factor 2
chr2_+_165595009 0.888 ENSMUST00000088132.6
Eya2
eyes absent 2 homolog (Drosophila)
chr5_-_140649018 0.881 ENSMUST00000042661.3
Ttyh3
tweety homolog 3 (Drosophila)
chr7_+_110627650 0.873 ENSMUST00000033054.8
Adm
adrenomedullin
chr5_+_119834663 0.854 ENSMUST00000018407.6
Tbx5
T-box 5
chr7_-_92874196 0.840 ENSMUST00000032877.9
4632434I11Rik
RIKEN cDNA 4632434I11 gene
chr5_+_64160207 0.825 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr7_+_126695355 0.818 ENSMUST00000130498.1
Bola2
bolA-like 2 (E. coli)
chr5_+_74195281 0.815 ENSMUST00000051937.7
Rasl11b
RAS-like, family 11, member B
chr17_+_15704963 0.809 ENSMUST00000024627.7
ENSMUST00000173311.1
Chd1

chromodomain helicase DNA binding protein 1

chr2_+_30416096 0.808 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr2_-_38644087 0.806 ENSMUST00000028083.5
Psmb7
proteasome (prosome, macropain) subunit, beta type 7
chr10_+_94688739 0.801 ENSMUST00000020212.4
Ccdc41
coiled-coil domain containing 41
chr12_+_109452833 0.793 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr6_+_124931378 0.780 ENSMUST00000032214.7
ENSMUST00000180095.1
Mlf2

myeloid leukemia factor 2

chr12_-_103242143 0.777 ENSMUST00000074416.3
Prima1
proline rich membrane anchor 1
chr16_+_20673517 0.776 ENSMUST00000115460.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr1_-_75506331 0.760 ENSMUST00000113567.2
ENSMUST00000113565.2
Obsl1

obscurin-like 1

chr8_+_85840971 0.749 ENSMUST00000053771.7
ENSMUST00000161850.1
Phkb

phosphorylase kinase beta

chr1_-_182282738 0.747 ENSMUST00000035295.5
Degs1
degenerative spermatocyte homolog 1 (Drosophila)
chr7_+_97480928 0.745 ENSMUST00000026126.8
Ints4
integrator complex subunit 4
chrX_+_161162994 0.742 ENSMUST00000077375.4
Scml2
sex comb on midleg-like 2 (Drosophila)
chr8_+_123477859 0.737 ENSMUST00000001520.7
Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr17_-_57247632 0.718 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr7_-_25477607 0.710 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
Ceacam1


carcinoembryonic antigen-related cell adhesion molecule 1


chr15_-_50890396 0.700 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr4_+_116877376 0.697 ENSMUST00000044823.3
Zswim5
zinc finger SWIM-type containing 5
chr14_+_28511344 0.668 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr6_+_43265582 0.661 ENSMUST00000031750.7
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chrX_+_56963325 0.657 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr18_-_38250558 0.634 ENSMUST00000181757.1
1700086O06Rik
RIKEN cDNA 1700086O06 gene
chr7_-_133015248 0.627 ENSMUST00000169570.1
Ctbp2
C-terminal binding protein 2
chr4_+_97777780 0.620 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr2_-_30093607 0.613 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr7_+_24884611 0.600 ENSMUST00000108428.1
Rps19
ribosomal protein S19
chr6_-_28397999 0.598 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr5_+_110653444 0.592 ENSMUST00000031478.5
Ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr17_-_27820445 0.579 ENSMUST00000114859.1
D17Wsu92e
DNA segment, Chr 17, Wayne State University 92, expressed
chr5_+_143403819 0.577 ENSMUST00000110731.2
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr4_+_137993445 0.552 ENSMUST00000105831.2
ENSMUST00000084214.5
Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chr19_-_10240689 0.538 ENSMUST00000088013.5
Myrf
myelin regulatory factor
chr15_-_97767644 0.536 ENSMUST00000128775.2
ENSMUST00000134885.2
Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chr15_-_64312636 0.525 ENSMUST00000177083.1
ENSMUST00000177371.1
Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

chr18_-_10610124 0.523 ENSMUST00000097670.3
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr7_-_132852606 0.522 ENSMUST00000120425.1
Mettl10
methyltransferase like 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.7 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
2.5 7.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
2.4 7.2 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
2.1 6.4 GO:0071918 urea transmembrane transport(GO:0071918)
2.0 8.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
1.8 10.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.6 9.7 GO:0060242 contact inhibition(GO:0060242)
1.5 6.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.5 9.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.3 5.3 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
1.3 4.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.2 3.6 GO:0036166 phenotypic switching(GO:0036166)
1.1 17.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.1 7.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.0 3.0 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.0 3.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.9 2.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.9 2.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.9 8.7 GO:0042473 outer ear morphogenesis(GO:0042473)
0.8 2.5 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.8 6.6 GO:0072615 interleukin-17 secretion(GO:0072615)
0.8 2.4 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.8 5.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.7 3.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.7 3.7 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.7 3.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.7 3.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.7 5.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.7 3.4 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.6 3.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.6 2.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6 4.2 GO:0030916 otic vesicle formation(GO:0030916)
0.6 1.8 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.6 3.4 GO:0002317 plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598)
0.6 3.9 GO:1902965 cellular response to testosterone stimulus(GO:0071394) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.6 2.2 GO:0015744 succinate transport(GO:0015744)
0.5 2.2 GO:1904706 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.5 2.7 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.5 2.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.5 5.0 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.5 3.5 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.5 1.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.5 1.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725)
0.4 1.4 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.3 0.7 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.3 15.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.3 1.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.3 7.2 GO:0043486 histone exchange(GO:0043486)
0.3 3.7 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.3 1.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.3 0.5 GO:0051795 positive regulation of catagen(GO:0051795)
0.3 1.8 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 2.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2 1.5 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) regulation of inorganic anion transmembrane transport(GO:1903795)
0.2 1.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.6 GO:0097421 liver regeneration(GO:0097421)
0.2 0.9 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2 0.7 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 1.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 1.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 1.9 GO:0060019 radial glial cell differentiation(GO:0060019)
0.2 1.0 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.2 0.8 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.2 1.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 1.2 GO:0032439 endosome localization(GO:0032439)
0.2 6.7 GO:0006270 DNA replication initiation(GO:0006270)
0.2 6.8 GO:0009299 mRNA transcription(GO:0009299)
0.2 0.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 3.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.9 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 1.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 1.6 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.2 2.4 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.2 1.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 1.3 GO:0001842 neural fold formation(GO:0001842)
0.2 1.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.2 1.8 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 3.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 2.5 GO:0051451 myoblast migration(GO:0051451)
0.2 2.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 1.2 GO:0015074 DNA integration(GO:0015074)
0.2 2.8 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 2.9 GO:0042711 maternal behavior(GO:0042711)
0.1 0.9 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 2.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 1.9 GO:0060033 anatomical structure regression(GO:0060033)
0.1 0.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.2 GO:0060596 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) mammary placode formation(GO:0060596)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.6 GO:0031508 chromatin remodeling at centromere(GO:0031055) pericentric heterochromatin assembly(GO:0031508)
0.1 0.6 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 2.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 1.4 GO:0046697 decidualization(GO:0046697)
0.1 1.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 1.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 1.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.4 GO:0002467 germinal center formation(GO:0002467)
0.1 0.3 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.2 GO:0070253 somatostatin secretion(GO:0070253)
0.1 0.3 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 2.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 1.7 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 1.0 GO:0042182 ketone catabolic process(GO:0042182)
0.1 0.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.5 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.6 GO:0072189 ureter development(GO:0072189)
0.1 0.7 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 1.8 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 1.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 1.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.5 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.2 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.8 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 3.6 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.0 0.4 GO:0070633 transepithelial transport(GO:0070633)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 2.3 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.4 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.4 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.7 GO:0016236 macroautophagy(GO:0016236)
0.0 0.7 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 1.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.8 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.7 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
3.2 9.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
3.2 9.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.2 3.7 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
1.1 6.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.0 3.0 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.9 2.8 GO:0005588 collagen type V trimer(GO:0005588)
0.8 3.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.8 5.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.7 2.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.7 4.0 GO:0061689 tricellular tight junction(GO:0061689)
0.6 3.4 GO:0005859 muscle myosin complex(GO:0005859)
0.4 6.7 GO:0042555 MCM complex(GO:0042555)
0.4 3.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4 3.4 GO:0031415 NatA complex(GO:0031415)
0.4 2.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.4 1.5 GO:0060187 cell pole(GO:0060187)
0.4 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.3 GO:0090537 CERF complex(GO:0090537)
0.3 1.2 GO:0045179 apical cortex(GO:0045179)
0.3 2.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 9.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 2.7 GO:0000796 condensin complex(GO:0000796)
0.2 1.4 GO:0034448 EGO complex(GO:0034448)
0.2 2.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 0.7 GO:0005745 m-AAA complex(GO:0005745)
0.2 0.5 GO:0000814 ESCRT II complex(GO:0000814)
0.1 3.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 12.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.5 GO:0046930 pore complex(GO:0046930)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.5 GO:0072487 MSL complex(GO:0072487)
0.1 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.1 1.7 GO:0005771 multivesicular body(GO:0005771)
0.1 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.0 1.0 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 18.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.6 GO:0005844 polysome(GO:0005844)
0.0 12.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.7 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.9 GO:0070469 respiratory chain(GO:0070469)
0.0 5.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.2 GO:0010008 endosome membrane(GO:0010008)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 15.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
2.5 7.5 GO:0004962 endothelin receptor activity(GO:0004962)
2.0 8.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.8 5.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
1.7 6.6 GO:0008142 oxysterol binding(GO:0008142)
1.1 6.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.9 2.8 GO:0070052 collagen V binding(GO:0070052)
0.8 17.9 GO:0070410 co-SMAD binding(GO:0070410)
0.7 2.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.7 2.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.7 3.4 GO:0005534 galactose binding(GO:0005534)
0.7 3.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.7 3.4 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.6 3.9 GO:0019841 retinol binding(GO:0019841)
0.5 3.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 2.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 12.1 GO:0070064 proline-rich region binding(GO:0070064)
0.4 1.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.4 1.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.4 1.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.3 1.4 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 1.0 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.3 1.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.3 3.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 2.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3 6.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 2.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 0.7 GO:0005118 sevenless binding(GO:0005118)
0.2 0.7 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 4.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 3.9 GO:0051861 glycolipid binding(GO:0051861)
0.2 0.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 3.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2 1.3 GO:0008242 omega peptidase activity(GO:0008242)
0.2 2.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 1.5 GO:0051434 BH3 domain binding(GO:0051434)
0.2 2.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 1.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 3.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 2.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 3.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 2.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 2.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.1 7.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 12.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 1.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.3 GO:0051378 serotonin binding(GO:0051378)
0.1 5.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 1.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.4 GO:0008143 poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.8 GO:0043495 protein anchor(GO:0043495)
0.1 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 7.3 GO:0004386 helicase activity(GO:0004386)
0.0 5.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 6.1 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 29.4 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 3.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 3.1 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.7 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 25.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 19.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 3.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 20.5 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 5.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 3.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 1.5 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 5.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 7.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 7.6 PID_E2F_PATHWAY E2F transcription factor network
0.1 3.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 3.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 4.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 4.0 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 2.3 ST_GAQ_PATHWAY G alpha q Pathway
0.1 2.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 3.0 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 1.0 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.9 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.1 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.6 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.7 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.4 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.6 20.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.4 13.5 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.4 4.2 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.3 9.7 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 9.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.3 6.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.3 3.9 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 2.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 3.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 1.7 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 3.8 REACTOME_KINESINS Genes involved in Kinesins
0.1 3.4 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.8 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 7.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 7.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 4.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.7 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 3.6 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 1.1 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 1.4 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.1 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 1.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.8 REACTOME_SIGNALING_BY_NOTCH1 Genes involved in Signaling by NOTCH1
0.0 1.2 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 2.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 6.2 REACTOME_TRANSLATION Genes involved in Translation
0.0 1.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells