Motif ID: Maf_Nrl
Z-value: 0.635
Transcription factors associated with Maf_Nrl:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Maf | ENSMUSG00000055435.6 | Maf |
Nrl | ENSMUSG00000040632.9 | Nrl |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Maf | mm10_v2_chr8_-_115707778_115707794 | -0.36 | 7.7e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.4 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
0.9 | 2.8 | GO:2000111 | cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) |
0.5 | 1.6 | GO:2000670 | positive regulation of dendritic cell apoptotic process(GO:2000670) |
0.5 | 1.4 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
0.4 | 1.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
0.4 | 2.6 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.4 | 1.2 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.4 | 1.5 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
0.3 | 1.7 | GO:0001661 | conditioned taste aversion(GO:0001661) |
0.3 | 1.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.3 | 1.1 | GO:0010511 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) |
0.3 | 1.3 | GO:0015671 | oxygen transport(GO:0015671) |
0.2 | 1.2 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
0.2 | 0.7 | GO:0002030 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) |
0.2 | 0.6 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.2 | 1.2 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.2 | 1.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.2 | 0.4 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) |
0.2 | 0.6 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
0.2 | 2.2 | GO:0046958 | nonassociative learning(GO:0046958) |
0.2 | 1.9 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
0.2 | 0.9 | GO:0018364 | peptidyl-glutamine methylation(GO:0018364) |
0.2 | 0.5 | GO:0021649 | vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) |
0.2 | 0.4 | GO:1900141 | regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) |
0.2 | 0.5 | GO:0010838 | positive regulation of keratinocyte proliferation(GO:0010838) |
0.2 | 0.5 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.2 | 1.1 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.2 | 0.8 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
0.2 | 1.1 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
0.2 | 0.5 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474) |
0.1 | 1.1 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.1 | 0.8 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.1 | 0.6 | GO:0015960 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
0.1 | 1.2 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
0.1 | 1.5 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
0.1 | 0.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.1 | 1.1 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
0.1 | 3.2 | GO:0030818 | negative regulation of cAMP biosynthetic process(GO:0030818) |
0.1 | 0.3 | GO:0048209 | regulation of vesicle targeting, to, from or within Golgi(GO:0048209) |
0.1 | 1.1 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 0.5 | GO:2000427 | eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683) positive regulation of apoptotic cell clearance(GO:2000427) |
0.1 | 1.0 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
0.1 | 0.4 | GO:0007603 | phototransduction, visible light(GO:0007603) |
0.1 | 0.5 | GO:0001927 | exocyst assembly(GO:0001927) |
0.1 | 0.6 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.1 | 0.8 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.1 | 0.8 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.1 | 0.4 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.1 | 3.4 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.1 | 0.5 | GO:0033034 | positive regulation of neutrophil apoptotic process(GO:0033031) positive regulation of myeloid cell apoptotic process(GO:0033034) |
0.1 | 1.1 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
0.1 | 1.0 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
0.1 | 0.9 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 0.4 | GO:1901911 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.1 | 0.4 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) |
0.1 | 0.4 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.1 | 0.5 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.1 | 0.4 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.1 | 0.2 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.0 | 0.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.4 | GO:1990000 | amyloid fibril formation(GO:1990000) |
0.0 | 0.1 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
0.0 | 0.4 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.0 | 0.1 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
0.0 | 0.3 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.0 | 0.3 | GO:0015879 | carnitine transport(GO:0015879) |
0.0 | 0.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.0 | 0.2 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
0.0 | 0.6 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.0 | 0.3 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
0.0 | 0.9 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
0.0 | 1.1 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.3 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.0 | 0.4 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.0 | 0.2 | GO:0048341 | paraxial mesoderm formation(GO:0048341) |
0.0 | 0.4 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.0 | 1.0 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.2 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
0.0 | 0.0 | GO:0032079 | positive regulation of endodeoxyribonuclease activity(GO:0032079) |
0.0 | 0.2 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
0.0 | 2.0 | GO:0045806 | negative regulation of endocytosis(GO:0045806) |
0.0 | 0.2 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.0 | 1.5 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 0.1 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.0 | 0.1 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
0.0 | 0.1 | GO:0090427 | embryonic nail plate morphogenesis(GO:0035880) negative regulation of keratinocyte differentiation(GO:0045617) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) activation of meiosis(GO:0090427) |
0.0 | 0.1 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.0 | 0.4 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
0.0 | 0.2 | GO:0021943 | interneuron migration from the subpallium to the cortex(GO:0021830) formation of radial glial scaffolds(GO:0021943) |
0.0 | 0.1 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
0.0 | 1.0 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
0.0 | 0.1 | GO:0009405 | pathogenesis(GO:0009405) |
0.0 | 0.1 | GO:0090168 | Golgi reassembly(GO:0090168) |
0.0 | 0.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.1 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.0 | 0.1 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.0 | 0.9 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.0 | 0.8 | GO:0006284 | base-excision repair(GO:0006284) |
0.0 | 0.3 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 0.0 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.0 | 0.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.0 | 0.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.0 | 1.0 | GO:0032418 | lysosome localization(GO:0032418) |
0.0 | 0.1 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 1.6 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
0.0 | 0.1 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
0.0 | 0.2 | GO:0036010 | protein localization to endosome(GO:0036010) |
0.0 | 0.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.4 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.5 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
0.0 | 0.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.0 | 0.2 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
0.0 | 0.4 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 0.5 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
0.0 | 0.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
0.0 | 0.2 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
0.0 | 0.4 | GO:2000036 | regulation of stem cell population maintenance(GO:2000036) |
0.0 | 0.0 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.0 | 0.1 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.0 | 0.7 | GO:0031623 | receptor internalization(GO:0031623) |
0.0 | 0.2 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.5 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.2 | GO:0043512 | inhibin A complex(GO:0043512) |
0.3 | 1.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.3 | 1.1 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
0.2 | 0.5 | GO:0005940 | septin ring(GO:0005940) |
0.2 | 0.5 | GO:0044299 | C-fiber(GO:0044299) |
0.2 | 1.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.2 | 1.7 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.1 | 0.6 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.1 | 1.0 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 0.6 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.1 | 0.3 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.1 | 0.4 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
0.1 | 1.1 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.1 | 1.1 | GO:0070852 | cell body fiber(GO:0070852) |
0.1 | 1.1 | GO:0030057 | desmosome(GO:0030057) |
0.1 | 1.1 | GO:0043196 | varicosity(GO:0043196) |
0.1 | 1.9 | GO:0071565 | nBAF complex(GO:0071565) |
0.1 | 0.8 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.1 | 0.4 | GO:0044305 | calyx of Held(GO:0044305) |
0.1 | 1.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.1 | 0.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 0.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.1 | 1.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.5 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.0 | 0.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.0 | 0.7 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 2.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.0 | 2.1 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 0.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 0.3 | GO:0034709 | methylosome(GO:0034709) |
0.0 | 0.2 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.0 | 0.2 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.0 | 1.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.0 | 1.6 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.6 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.0 | 0.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.8 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 0.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 1.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 0.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.5 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 3.4 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 6.3 | GO:0014069 | postsynaptic density(GO:0014069) |
0.0 | 1.1 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.8 | GO:0005795 | Golgi stack(GO:0005795) |
0.0 | 4.1 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 0.3 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 0.8 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.2 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 0.2 | GO:0043203 | axon hillock(GO:0043203) |
0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 3.1 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 0.1 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.2 | GO:0060170 | ciliary membrane(GO:0060170) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.4 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.6 | 1.7 | GO:0070905 | serine binding(GO:0070905) |
0.4 | 1.1 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
0.3 | 1.3 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
0.3 | 1.2 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.3 | 1.1 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.2 | 0.7 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958) |
0.2 | 1.6 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.2 | 1.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.2 | 0.6 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.2 | 1.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.2 | 2.8 | GO:0003680 | AT DNA binding(GO:0003680) |
0.2 | 0.5 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.2 | 1.5 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.2 | 0.8 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.1 | 0.7 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.1 | 0.4 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
0.1 | 0.7 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.1 | 0.4 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.1 | 0.5 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.1 | 0.6 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.1 | 1.1 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.1 | 0.3 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.1 | 1.1 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
0.1 | 0.4 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
0.1 | 0.3 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.1 | 2.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 0.3 | GO:0005124 | scavenger receptor binding(GO:0005124) |
0.1 | 0.6 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.1 | 0.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.5 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.1 | 0.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.1 | 1.1 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.1 | 0.6 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.1 | 0.4 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.1 | 0.8 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.1 | 0.8 | GO:0019104 | DNA N-glycosylase activity(GO:0019104) |
0.1 | 0.9 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
0.1 | 0.5 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
0.1 | 1.6 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.6 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
0.1 | 0.3 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.1 | 0.9 | GO:0055103 | ligase regulator activity(GO:0055103) |
0.0 | 0.2 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.0 | 0.4 | GO:0048185 | activin binding(GO:0048185) |
0.0 | 0.4 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
0.0 | 0.4 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.0 | 0.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.0 | 0.3 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.3 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.0 | 0.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.2 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.0 | 0.1 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.0 | 0.3 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 0.5 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.0 | 0.1 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.0 | 2.5 | GO:0030295 | protein kinase activator activity(GO:0030295) |
0.0 | 0.2 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.0 | 0.5 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.4 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 6.3 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
0.0 | 0.7 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 0.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.0 | 3.7 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 1.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 1.5 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.3 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.0 | 0.2 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 0.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.1 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.0 | 0.4 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.0 | 1.4 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.4 | GO:0042608 | T cell receptor binding(GO:0042608) |
0.0 | 0.6 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.3 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.5 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.8 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.2 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
0.0 | 1.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.2 | GO:0035198 | miRNA binding(GO:0035198) |
0.0 | 0.1 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.0 | 0.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 0.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.0 | 0.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.2 | GO:0042287 | MHC protein binding(GO:0042287) |
0.0 | 0.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 1.0 | GO:0019838 | growth factor binding(GO:0019838) |
0.0 | 0.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.9 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.1 | 2.9 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.1 | 1.1 | PID_GMCSF_PATHWAY | GMCSF-mediated signaling events |
0.1 | 1.1 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 1.6 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
0.0 | 1.6 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 0.5 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.0 | 2.1 | PID_SHP2_PATHWAY | SHP2 signaling |
0.0 | 0.6 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
0.0 | 1.5 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
0.0 | 1.5 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 1.2 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 0.6 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
0.0 | 0.9 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 1.0 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
0.0 | 3.0 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 1.0 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
0.0 | 0.5 | PID_ARF_3PATHWAY | Arf1 pathway |
0.0 | 0.4 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.3 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 0.8 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 0.8 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 0.2 | PID_IL1_PATHWAY | IL1-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.1 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
0.3 | 3.4 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.3 | 1.2 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.2 | 2.3 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 2.9 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.1 | 1.2 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.1 | 1.1 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.1 | 2.1 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.1 | 0.5 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
0.1 | 2.8 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.1 | 2.8 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.1 | 0.4 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.1 | 2.6 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.1 | 0.8 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.1 | 0.2 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.0 | 0.4 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.0 | 0.5 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 1.3 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 0.7 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 1.1 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 0.8 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
0.0 | 0.7 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
0.0 | 0.8 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.0 | 0.8 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.6 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.0 | 1.1 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.0 | 0.5 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | Genes involved in Activation of Genes by ATF4 |
0.0 | 0.6 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.0 | 0.4 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.3 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.1 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.0 | 0.6 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
0.0 | 0.3 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.0 | 0.3 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 0.4 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |