Motif ID: Mafa

Z-value: 1.200


Transcription factors associated with Mafa:

Gene SymbolEntrez IDGene Name
Mafa ENSMUSG00000047591.4 Mafa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafamm10_v2_chr15_-_75747922_75747922-0.447.9e-04Click!


Activity profile for motif Mafa.

activity profile for motif Mafa


Sorted Z-values histogram for motif Mafa

Sorted Z-values for motif Mafa



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafa

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_98032983 19.816 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr9_-_98033181 17.624 ENSMUST00000035027.6
Clstn2
calsyntenin 2
chr14_+_119138415 15.414 ENSMUST00000065904.3
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr1_-_169747634 14.449 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr16_-_17576631 12.798 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
Slc7a4


solute carrier family 7 (cationic amino acid transporter, y+ system), member 4


chr1_-_136260873 12.553 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr4_+_102254993 11.672 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr4_+_102254739 11.211 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr7_+_54835959 10.830 ENSMUST00000082373.6
Luzp2
leucine zipper protein 2
chr1_-_38836090 7.886 ENSMUST00000147695.1
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr8_-_70487314 7.708 ENSMUST00000045286.7
Tmem59l
transmembrane protein 59-like
chr11_-_66525964 6.842 ENSMUST00000066679.6
Shisa6
shisa homolog 6 (Xenopus laevis)
chr11_-_66525795 6.675 ENSMUST00000123454.1
Shisa6
shisa homolog 6 (Xenopus laevis)
chr10_+_58813359 6.467 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chrX_-_73869804 6.383 ENSMUST00000066576.5
ENSMUST00000114430.1
L1cam

L1 cell adhesion molecule

chr12_+_3365108 5.704 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr5_-_142509653 5.661 ENSMUST00000110784.1
Radil
Ras association and DIL domains
chr16_-_74411292 5.219 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr16_-_74411776 5.104 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr19_+_27217011 5.081 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr19_+_27217357 4.945 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chr6_-_35308110 4.504 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr16_+_91269759 4.478 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr18_-_36197343 4.349 ENSMUST00000115713.1
ENSMUST00000115712.1
Nrg2

neuregulin 2

chr10_-_84440591 4.331 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr12_-_86884808 4.224 ENSMUST00000038422.6
Irf2bpl
interferon regulatory factor 2 binding protein-like
chr5_+_111417263 4.185 ENSMUST00000094463.4
Mn1
meningioma 1
chr4_+_43406435 4.143 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr5_-_124187150 4.133 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr4_+_21931291 3.826 ENSMUST00000029908.7
Faxc
failed axon connections homolog (Drosophila)
chr13_+_4233730 3.818 ENSMUST00000081326.6
Akr1c19
aldo-keto reductase family 1, member C19
chr4_+_42035113 3.817 ENSMUST00000098127.1
Gm10597
predicted gene 10597
chr12_+_105453831 3.687 ENSMUST00000178224.1
D430019H16Rik
RIKEN cDNA D430019H16 gene
chrX_-_95444789 3.593 ENSMUST00000084535.5
Amer1
APC membrane recruitment 1
chr17_-_47010513 3.343 ENSMUST00000113337.2
ENSMUST00000113335.2
Ubr2

ubiquitin protein ligase E3 component n-recognin 2

chr9_-_105131775 3.218 ENSMUST00000035179.6
Nudt16
nudix (nucleoside diphosphate linked moiety X)-type motif 16
chrX_+_152178945 3.066 ENSMUST00000096275.4
Iqsec2
IQ motif and Sec7 domain 2
chrX_-_20950597 2.917 ENSMUST00000009550.7
Elk1
ELK1, member of ETS oncogene family
chr2_-_125506385 2.861 ENSMUST00000028633.6
Fbn1
fibrillin 1
chr8_+_93810832 2.820 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr9_-_51077064 2.750 ENSMUST00000098782.3
Layn
layilin
chr11_-_107337556 2.674 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr10_-_75932468 2.468 ENSMUST00000120281.1
ENSMUST00000000924.6
Mmp11

matrix metallopeptidase 11

chr4_-_35845204 2.396 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr14_+_64588112 2.375 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr11_+_87595646 2.276 ENSMUST00000134216.1
Mtmr4
myotubularin related protein 4
chr17_-_46752170 2.222 ENSMUST00000121671.1
ENSMUST00000059844.6
Cnpy3

canopy 3 homolog (zebrafish)

chr1_-_121328024 2.128 ENSMUST00000003818.7
Insig2
insulin induced gene 2
chr5_+_24423805 2.072 ENSMUST00000153274.1
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr8_-_84937347 2.003 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr4_-_59138983 1.935 ENSMUST00000107547.1
AI481877
expressed sequence AI481877
chr7_-_67759735 1.911 ENSMUST00000074233.4
ENSMUST00000051389.8
Synm

synemin, intermediate filament protein

chr1_-_121327776 1.846 ENSMUST00000160688.1
Insig2
insulin induced gene 2
chr9_+_108002501 1.823 ENSMUST00000035214.4
ENSMUST00000175874.1
Ip6k1

inositol hexaphosphate kinase 1

chr1_-_121327734 1.693 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2

insulin induced gene 2

chr4_+_59003121 1.619 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr7_+_140856957 1.569 ENSMUST00000026558.6
Ric8
resistance to inhibitors of cholinesterase 8 homolog (C. elegans)
chr11_-_119228461 1.503 ENSMUST00000036113.3
Tbc1d16
TBC1 domain family, member 16
chr1_-_121327672 1.459 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2


insulin induced gene 2


chr8_-_105565985 1.396 ENSMUST00000013304.7
Atp6v0d1
ATPase, H+ transporting, lysosomal V0 subunit D1
chr15_-_25413752 1.357 ENSMUST00000058845.7
Basp1
brain abundant, membrane attached signal protein 1
chr9_-_45906837 1.207 ENSMUST00000161203.1
ENSMUST00000058720.5
ENSMUST00000160699.1
Rnf214


ring finger protein 214


chr17_-_47611449 1.148 ENSMUST00000024783.8
Bysl
bystin-like
chr1_-_105356658 1.147 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152

ring finger protein 152

chr10_-_81600857 1.126 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
Tle6


transducin-like enhancer of split 6, homolog of Drosophila E(spl)


chr13_+_93771656 1.087 ENSMUST00000091403.4
Arsb
arylsulfatase B
chr9_-_109059711 0.926 ENSMUST00000061973.4
Trex1
three prime repair exonuclease 1
chr4_+_155601854 0.839 ENSMUST00000118607.1
Slc35e2
solute carrier family 35, member E2
chrX_+_151047170 0.815 ENSMUST00000026296.7
Fgd1
FYVE, RhoGEF and PH domain containing 1
chrX_-_122397351 0.811 ENSMUST00000079490.4
Nap1l3
nucleosome assembly protein 1-like 3
chr11_+_50174839 0.797 ENSMUST00000020647.3
3010026O09Rik
RIKEN cDNA 3010026O09 gene
chr9_-_48835932 0.794 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr8_+_60993189 0.747 ENSMUST00000034065.7
ENSMUST00000120689.1
Nek1

NIMA (never in mitosis gene a)-related expressed kinase 1

chr5_-_24423516 0.735 ENSMUST00000030814.6
Cdk5
cyclin-dependent kinase 5
chr9_-_109059216 0.648 ENSMUST00000112053.1
Trex1
three prime repair exonuclease 1
chr10_-_62507737 0.634 ENSMUST00000020271.6
Srgn
serglycin
chr1_+_87183310 0.483 ENSMUST00000044533.8
Prss56
protease, serine 56
chr17_+_47611570 0.481 ENSMUST00000024778.2
Med20
mediator complex subunit 20
chr1_+_146495621 0.337 ENSMUST00000074622.4
Brinp3
bone morphogenetic protein/retinoic acid inducible neural specific 3
chrX_+_104482774 0.329 ENSMUST00000087867.5
Uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr2_+_36230426 0.306 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chrX_-_97377150 0.242 ENSMUST00000113832.1
Eda2r
ectodysplasin A2 receptor
chr5_+_124629050 0.167 ENSMUST00000037865.8
Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
chr9_-_65580040 0.166 ENSMUST00000068944.7
Plekho2
pleckstrin homology domain containing, family O member 2
chr13_+_96924674 0.136 ENSMUST00000171324.1
Gcnt4
glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
chr9_+_45906513 0.075 ENSMUST00000039059.6
Pcsk7
proprotein convertase subtilisin/kexin type 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
2.6 15.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
2.0 10.0 GO:0034436 glycoprotein transport(GO:0034436)
1.8 22.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
1.0 2.9 GO:1903011 negative regulation of bone development(GO:1903011)
0.8 3.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.8 3.2 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.7 13.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.6 6.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.6 3.6 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.6 4.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5 7.1 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.5 4.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.5 37.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 4.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.4 12.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.3 4.5 GO:0008272 sulfate transport(GO:0008272)
0.2 13.8 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.8 GO:0006020 inositol metabolic process(GO:0006020)
0.2 3.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.2 0.8 GO:0048133 NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.2 2.5 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 1.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.4 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 2.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 1.6 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 7.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 2.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 5.7 GO:0072384 organelle transport along microtubule(GO:0072384)
0.1 1.9 GO:0003009 skeletal muscle contraction(GO:0003009) intermediate filament cytoskeleton organization(GO:0045104)
0.1 5.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 4.5 GO:0048663 neuron fate commitment(GO:0048663)
0.1 4.3 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 1.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 1.5 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 1.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 2.1 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 2.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.1 GO:0007584 response to nutrient(GO:0007584)
0.0 8.9 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 2.2 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 2.3 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.9 22.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.8 10.0 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.6 5.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.5 6.4 GO:0044294 dendritic growth cone(GO:0044294)
0.3 13.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 10.3 GO:0030673 axolemma(GO:0030673)
0.2 0.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.9 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.2 2.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 37.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.1 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 6.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 2.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.9 GO:0043679 axon terminus(GO:0043679)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.5 GO:0005769 early endosome(GO:0005769)
0.0 3.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 42.7 GO:0016021 integral component of membrane(GO:0016021)
0.0 4.5 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
3.3 10.0 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
1.4 4.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.1 10.3 GO:0008046 axon guidance receptor activity(GO:0008046)
1.1 1.1 GO:0004065 arylsulfatase activity(GO:0004065)
1.1 6.4 GO:0033691 sialic acid binding(GO:0033691)
0.7 22.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.6 3.3 GO:0070728 leucine binding(GO:0070728)
0.5 3.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.5 2.8 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 1.8 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.4 1.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 14.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 0.7 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 2.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 7.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 2.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 12.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 1.9 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 3.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 5.7 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.1 3.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 25.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 4.3 GO:0002039 p53 binding(GO:0002039)
0.0 5.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 6.6 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 2.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 4.1 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 1.4 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.3 9.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 2.9 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 5.7 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.2 6.4 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 0.7 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.8 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.5 23.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.4 15.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.3 10.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.2 2.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 4.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 14.4 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.2 5.7 REACTOME_KINESINS Genes involved in Kinesins
0.2 6.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.2 2.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.9 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 1.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 2.9 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK