Motif ID: Max_Mycn

Z-value: 2.709

Transcription factors associated with Max_Mycn:

Gene SymbolEntrez IDGene Name
Max ENSMUSG00000059436.6 Max
Mycn ENSMUSG00000037169.8 Mycn

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maxmm10_v2_chr12_-_76962178_76962248-0.367.8e-03Click!
Mycnmm10_v2_chr12_-_12940600_129406160.162.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Max_Mycn

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_135251209 26.437 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr5_+_140607334 24.003 ENSMUST00000031555.1
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_137796350 21.858 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr4_-_143299498 21.174 ENSMUST00000030317.7
Pdpn
podoplanin
chr7_+_144896523 20.978 ENSMUST00000033389.5
Fgf15
fibroblast growth factor 15
chr4_-_143299463 19.274 ENSMUST00000119654.1
Pdpn
podoplanin
chr12_+_117843873 17.520 ENSMUST00000176735.1
ENSMUST00000177339.1
Cdca7l

cell division cycle associated 7 like

chr11_-_89302545 16.962 ENSMUST00000061728.3
Nog
noggin
chr10_+_127063599 15.886 ENSMUST00000120226.1
ENSMUST00000133115.1
Cdk4

cyclin-dependent kinase 4

chr8_+_27260327 15.526 ENSMUST00000033880.5
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr14_-_79301623 15.380 ENSMUST00000022595.7
Rgcc
regulator of cell cycle
chr10_-_30842765 15.312 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr8_-_46294592 15.145 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr11_-_94601862 15.129 ENSMUST00000103164.3
Acsf2
acyl-CoA synthetase family member 2
chr16_+_30065333 14.533 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr10_-_77113676 14.316 ENSMUST00000072755.4
ENSMUST00000105409.1
Col18a1

collagen, type XVIII, alpha 1

chr17_+_46496753 14.195 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr5_+_114130386 14.159 ENSMUST00000031587.6
Ung
uracil DNA glycosylase
chr2_+_156840966 14.023 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr11_-_12026732 13.746 ENSMUST00000143915.1
Grb10
growth factor receptor bound protein 10
chr9_-_8004585 13.430 ENSMUST00000086580.5
ENSMUST00000065353.6
Yap1

yes-associated protein 1

chr17_-_35000848 13.161 ENSMUST00000166828.3
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr11_-_60811228 13.058 ENSMUST00000018744.8
Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr10_+_127063527 13.033 ENSMUST00000006911.5
Cdk4
cyclin-dependent kinase 4
chr3_+_104638658 12.736 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chrX_-_155338460 12.447 ENSMUST00000026328.4
Prdx4
peroxiredoxin 4
chr2_+_121449362 12.384 ENSMUST00000110615.1
ENSMUST00000099475.5
Serf2

small EDRK-rich factor 2

chr5_-_45639501 12.084 ENSMUST00000016023.7
Fam184b
family with sequence similarity 184, member B
chr1_+_172499948 12.027 ENSMUST00000111230.1
Tagln2
transgelin 2
chr12_+_17544873 11.729 ENSMUST00000171737.1
Odc1
ornithine decarboxylase, structural 1
chr8_+_48109949 11.713 ENSMUST00000170263.2
ENSMUST00000033966.6
Dctd

dCMP deaminase

chr14_-_20181773 11.639 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr8_+_94172618 11.468 ENSMUST00000034214.6
Mt2
metallothionein 2
chr15_-_75909289 11.391 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr9_-_119578981 11.374 ENSMUST00000117911.1
ENSMUST00000120420.1
Scn5a

sodium channel, voltage-gated, type V, alpha

chr9_+_107587711 11.361 ENSMUST00000010192.5
Ifrd2
interferon-related developmental regulator 2
chr3_-_95882193 11.171 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr12_+_117843489 11.141 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr4_-_122961173 10.851 ENSMUST00000030408.5
ENSMUST00000127047.1
Mfsd2a

major facilitator superfamily domain containing 2A

chr19_-_40271506 10.845 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr9_-_114781986 10.788 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr3_+_145758674 10.639 ENSMUST00000029845.8
Ddah1
dimethylarginine dimethylaminohydrolase 1
chrX_-_134541847 10.538 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr2_-_144270852 10.464 ENSMUST00000110030.3
Snx5
sorting nexin 5
chr6_+_108660616 10.395 ENSMUST00000032194.4
Bhlhe40
basic helix-loop-helix family, member e40
chr11_-_12026237 10.198 ENSMUST00000150972.1
Grb10
growth factor receptor bound protein 10
chr15_-_75909319 10.039 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr1_-_165194310 10.037 ENSMUST00000043338.4
Sft2d2
SFT2 domain containing 2
chr3_-_157925056 9.833 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr19_-_15924928 9.807 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chr11_-_69920892 9.730 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr2_+_84840612 9.710 ENSMUST00000111625.1
Slc43a1
solute carrier family 43, member 1
chr5_+_129020069 9.679 ENSMUST00000031383.7
ENSMUST00000111343.1
Ran

RAN, member RAS oncogene family

chr5_-_139460501 9.659 ENSMUST00000066052.7
3110082I17Rik
RIKEN cDNA 3110082I17 gene
chr10_+_79854618 9.651 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chr7_-_16387791 9.593 ENSMUST00000094815.3
Sae1
SUMO1 activating enzyme subunit 1
chr17_+_45563928 9.552 ENSMUST00000041353.6
Slc35b2
solute carrier family 35, member B2
chr11_-_69921190 9.542 ENSMUST00000108607.1
Eif5a
eukaryotic translation initiation factor 5A
chr17_-_24960620 9.493 ENSMUST00000024981.7
Hn1l
hematological and neurological expressed 1-like
chr2_+_144270900 9.478 ENSMUST00000028910.2
ENSMUST00000110027.1
Mgme1

mitochondrial genome maintainance exonuclease 1

chr9_-_63757933 9.458 ENSMUST00000034973.3
Smad3
SMAD family member 3
chr8_+_75093591 9.421 ENSMUST00000005548.6
Hmox1
heme oxygenase (decycling) 1
chr5_+_108694222 9.357 ENSMUST00000013633.8
ENSMUST00000112560.3
Fgfrl1

fibroblast growth factor receptor-like 1

chr17_+_56303396 9.339 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr4_-_132757162 9.285 ENSMUST00000030709.8
Smpdl3b
sphingomyelin phosphodiesterase, acid-like 3B
chr5_+_24428208 9.271 ENSMUST00000115049.2
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr9_-_43239816 9.187 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr19_-_36919606 9.176 ENSMUST00000057337.7
Fgfbp3
fibroblast growth factor binding protein 3
chr5_-_137314175 9.038 ENSMUST00000024119.9
Trip6
thyroid hormone receptor interactor 6
chr8_+_48110156 9.034 ENSMUST00000174379.1
Dctd
dCMP deaminase
chr2_-_105399286 9.010 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr11_+_70000578 8.748 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr7_+_65862029 8.710 ENSMUST00000055576.5
ENSMUST00000098391.4
Pcsk6

proprotein convertase subtilisin/kexin type 6

chrX_+_93286499 8.700 ENSMUST00000046565.7
ENSMUST00000113947.2
Arx

aristaless related homeobox

chr8_+_12395287 8.679 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr5_-_76951560 8.648 ENSMUST00000140076.1
Ppat
phosphoribosyl pyrophosphate amidotransferase
chr9_+_95637601 8.547 ENSMUST00000015498.8
Pcolce2
procollagen C-endopeptidase enhancer 2
chr7_+_46845832 8.501 ENSMUST00000048209.9
ENSMUST00000092621.4
Ldha

lactate dehydrogenase A

chr15_+_34238026 8.498 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr7_-_25250720 8.461 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chrX_+_36328353 8.372 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr13_-_81710937 8.295 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr1_+_55088132 8.237 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr5_-_77095225 8.207 ENSMUST00000120827.2
ENSMUST00000113453.2
Hopx

HOP homeobox

chr2_-_84670659 8.158 ENSMUST00000102646.1
ENSMUST00000102647.3
2700094K13Rik

RIKEN cDNA 2700094K13 gene

chr7_-_127260677 8.114 ENSMUST00000035276.4
Dctpp1
dCTP pyrophosphatase 1
chr6_-_95718800 7.997 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr6_+_108660772 7.973 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr2_+_72476225 7.949 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr1_-_55088024 7.899 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr9_-_48480540 7.819 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr1_+_166254095 7.817 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr10_+_79854658 7.809 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr2_+_118814237 7.808 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr2_+_71528657 7.803 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr4_+_101419696 7.708 ENSMUST00000131397.1
ENSMUST00000133055.1
Ak4

adenylate kinase 4

chr1_-_161251153 7.647 ENSMUST00000051925.4
ENSMUST00000071718.5
Prdx6

peroxiredoxin 6

chr2_+_72476159 7.603 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr11_-_96005872 7.498 ENSMUST00000013559.2
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr2_-_84670727 7.465 ENSMUST00000117299.2
2700094K13Rik
RIKEN cDNA 2700094K13 gene
chr1_+_175880775 7.389 ENSMUST00000039725.6
Exo1
exonuclease 1
chr9_+_44134562 7.383 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr5_-_52566264 7.333 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr10_+_11609256 7.295 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr11_-_93968293 7.259 ENSMUST00000170303.1
Gm20390
predicted gene 20390
chr14_+_46882854 7.250 ENSMUST00000022386.8
ENSMUST00000100672.3
Samd4

sterile alpha motif domain containing 4

chr1_+_191098414 7.250 ENSMUST00000027943.4
Batf3
basic leucine zipper transcription factor, ATF-like 3
chr11_-_69921329 7.113 ENSMUST00000108613.3
ENSMUST00000043419.3
ENSMUST00000070996.4
Eif5a


eukaryotic translation initiation factor 5A


chr3_-_79842662 7.097 ENSMUST00000029568.1
Tmem144
transmembrane protein 144
chr10_+_22158566 7.075 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr11_-_78550777 7.060 ENSMUST00000103242.4
Tmem97
transmembrane protein 97
chr5_+_76951307 7.034 ENSMUST00000031160.9
ENSMUST00000120912.1
ENSMUST00000117536.1
Paics


phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase


chr8_+_119446719 7.015 ENSMUST00000098363.3
Necab2
N-terminal EF-hand calcium binding protein 2
chr5_+_93093428 7.006 ENSMUST00000074733.7
Sept11
septin 11
chr11_+_117809687 6.987 ENSMUST00000120928.1
ENSMUST00000175737.1
Syngr2

synaptogyrin 2

chr14_+_115042752 6.980 ENSMUST00000134140.2
Mir17hg
Mir17 host gene 1 (non-protein coding)
chrX_+_10717390 6.980 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr8_+_12385769 6.938 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr5_-_140389188 6.909 ENSMUST00000031539.7
Snx8
sorting nexin 8
chr15_-_75909543 6.887 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr14_-_54577578 6.849 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr11_-_93968242 6.845 ENSMUST00000107844.2
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr17_-_25570678 6.807 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr11_+_69045640 6.806 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr14_-_50924626 6.798 ENSMUST00000160375.1
ENSMUST00000162177.1
ENSMUST00000159292.1
Osgep


O-sialoglycoprotein endopeptidase


chr15_+_72913357 6.787 ENSMUST00000166418.2
Gm3150
predicted gene 3150
chr12_+_108334341 6.767 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr3_-_101110278 6.717 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr2_+_84839395 6.615 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr5_+_45493374 6.582 ENSMUST00000046122.6
Lap3
leucine aminopeptidase 3
chrX_+_10717451 6.581 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr2_-_144270504 6.572 ENSMUST00000028909.4
Snx5
sorting nexin 5
chr11_-_12037391 6.564 ENSMUST00000093321.5
Grb10
growth factor receptor bound protein 10
chr16_-_17125106 6.562 ENSMUST00000093336.6
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr2_+_118814195 6.540 ENSMUST00000110842.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr1_-_17097839 6.526 ENSMUST00000038382.4
Jph1
junctophilin 1
chr6_+_117907795 6.516 ENSMUST00000167657.1
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr7_+_46847128 6.507 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr1_-_153549697 6.484 ENSMUST00000041874.7
Npl
N-acetylneuraminate pyruvate lyase
chr9_-_22389113 6.468 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr3_-_88410295 6.456 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr8_+_14911663 6.430 ENSMUST00000084207.5
ENSMUST00000161162.1
ENSMUST00000110800.2
Arhgef10


Rho guanine nucleotide exchange factor (GEF) 10


chr3_-_95882232 6.421 ENSMUST00000161866.1
Gm129
predicted gene 129
chr4_-_141874879 6.413 ENSMUST00000036854.3
Efhd2
EF hand domain containing 2
chr12_+_108306184 6.404 ENSMUST00000021685.6
Hhipl1
hedgehog interacting protein-like 1
chr18_-_74961252 6.397 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr17_+_35001282 6.388 ENSMUST00000174260.1
Vars
valyl-tRNA synthetase
chr12_+_112644828 6.337 ENSMUST00000021728.4
ENSMUST00000109755.3
Siva1

SIVA1, apoptosis-inducing factor

chr14_+_50924968 6.335 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
Apex1


apurinic/apyrimidinic endonuclease 1


chr10_+_56377300 6.333 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr17_+_35000987 6.303 ENSMUST00000087315.7
ENSMUST00000173584.1
Vars

valyl-tRNA synthetase

chr9_+_21368014 6.289 ENSMUST00000067646.4
ENSMUST00000115414.1
Ilf3

interleukin enhancer binding factor 3

chr14_+_120911177 6.289 ENSMUST00000032898.7
Ipo5
importin 5
chr4_-_45108038 6.279 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr3_+_93520473 6.278 ENSMUST00000029515.4
S100a11
S100 calcium binding protein A11 (calgizzarin)
chr10_-_75860250 6.255 ENSMUST00000038169.6
Mif
macrophage migration inhibitory factor
chr3_+_87906321 6.237 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr14_-_118237016 6.212 ENSMUST00000170662.1
Sox21
SRY-box containing gene 21
chr11_+_88718442 6.139 ENSMUST00000138007.1
C030037D09Rik
RIKEN cDNA C030037D09 gene
chr3_-_101307079 6.132 ENSMUST00000097146.2
Gm10355
predicted gene 10355
chr13_-_49652714 6.103 ENSMUST00000021818.7
Cenpp
centromere protein P
chr9_-_54661870 6.082 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr3_+_137864573 6.074 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr6_-_6217023 6.055 ENSMUST00000015256.8
Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr5_+_38220470 6.037 ENSMUST00000087514.2
ENSMUST00000130721.1
ENSMUST00000123207.1
ENSMUST00000132190.1
ENSMUST00000152066.1
ENSMUST00000155300.1
Lyar





Ly1 antibody reactive clone





chr11_+_51619731 6.031 ENSMUST00000127405.1
Nhp2
NHP2 ribonucleoprotein
chr6_+_90462562 6.014 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr4_-_55532453 5.980 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chrX_+_142681398 5.975 ENSMUST00000112889.1
ENSMUST00000101198.2
ENSMUST00000112891.1
ENSMUST00000087333.2
Tmem164



transmembrane protein 164



chr2_-_181693810 5.974 ENSMUST00000108776.1
ENSMUST00000108771.1
ENSMUST00000108779.1
ENSMUST00000108769.1
ENSMUST00000108772.1
ENSMUST00000002532.2
Rgs19





regulator of G-protein signaling 19





chr19_+_59322287 5.968 ENSMUST00000086764.5
Rps12-ps3
ribosomal protein S12, pseudogene 3
chr5_+_38220628 5.949 ENSMUST00000114106.1
Lyar
Ly1 antibody reactive clone
chr9_-_26806384 5.926 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
Glb1l2


galactosidase, beta 1-like 2


chr19_-_4615647 5.902 ENSMUST00000113822.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr5_+_37338455 5.885 ENSMUST00000056365.8
Evc2
Ellis van Creveld syndrome 2
chr9_+_21411824 5.869 ENSMUST00000002902.6
Qtrt1
queuine tRNA-ribosyltransferase 1
chr5_+_76951382 5.846 ENSMUST00000141687.1
Paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr18_+_35553401 5.828 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr2_+_25180737 5.771 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr2_+_118813995 5.768 ENSMUST00000134661.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr5_-_110780569 5.767 ENSMUST00000149208.1
ENSMUST00000031483.8
ENSMUST00000086643.5
ENSMUST00000170468.1
ENSMUST00000031481.6
Pus1




pseudouridine synthase 1




chr17_-_35000746 5.756 ENSMUST00000163360.1
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr1_+_72824482 5.747 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr4_+_101419277 5.717 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4


adenylate kinase 4


chr16_-_78376758 5.707 ENSMUST00000023570.7
Btg3
B cell translocation gene 3
chr13_-_56296551 5.693 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr9_+_120127766 5.679 ENSMUST00000035105.5
Rpsa
ribosomal protein SA
chr3_-_108722281 5.674 ENSMUST00000029482.9
Gpsm2
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr17_+_34982099 5.601 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_34982154 5.593 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_-_17056669 5.583 ENSMUST00000037762.4
Hif3a
hypoxia inducible factor 3, alpha subunit
chr2_+_167777467 5.544 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr9_+_7764041 5.531 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr11_+_69935894 5.503 ENSMUST00000149194.1
Ybx2
Y box protein 2
chr13_-_119408985 5.502 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr9_-_114390633 5.486 ENSMUST00000084881.4
Crtap
cartilage associated protein
chr1_+_71557149 5.449 ENSMUST00000027384.5
Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr17_-_10319324 5.433 ENSMUST00000097414.3
ENSMUST00000042296.7
Qk

quaking

chr11_+_117849223 5.406 ENSMUST00000081387.4
Birc5
baculoviral IAP repeat-containing 5
chr6_+_56832059 5.402 ENSMUST00000031795.7
Fkbp9
FK506 binding protein 9

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.1 36.4 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
8.8 26.4 GO:1990523 bone regeneration(GO:1990523)
8.1 40.4 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
7.2 28.9 GO:0010288 response to lead ion(GO:0010288)
6.6 26.2 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
5.5 33.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
5.3 5.3 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
5.1 20.5 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
4.8 24.0 GO:0007386 compartment pattern specification(GO:0007386)
4.7 14.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
4.5 13.6 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
4.5 13.6 GO:0006059 hexitol metabolic process(GO:0006059)
4.2 17.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
4.1 8.1 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
4.0 20.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
3.9 11.7 GO:0009446 putrescine biosynthetic process(GO:0009446)
3.9 11.7 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
3.8 11.4 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
3.6 14.5 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
3.6 14.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
3.4 30.5 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
3.2 16.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
3.2 12.7 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
3.0 15.2 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
2.9 8.7 GO:0021759 globus pallidus development(GO:0021759)
2.9 8.7 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
2.8 14.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
2.7 10.9 GO:1990379 lipid transport across blood brain barrier(GO:1990379)
2.7 10.7 GO:0072197 ureter morphogenesis(GO:0072197)
2.6 5.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
2.6 15.8 GO:1990928 response to amino acid starvation(GO:1990928)
2.6 13.1 GO:0072719 cellular response to cisplatin(GO:0072719)
2.6 7.8 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
2.5 10.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
2.5 27.8 GO:0006228 UTP biosynthetic process(GO:0006228)
2.5 12.6 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
2.5 7.5 GO:0046032 ADP catabolic process(GO:0046032)
2.5 7.5 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
2.4 9.8 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
2.4 9.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
2.4 9.6 GO:0032053 ciliary basal body organization(GO:0032053)
2.3 7.0 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167) regulation of G-protein coupled receptor internalization(GO:1904020)
2.3 9.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
2.3 11.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
2.2 11.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.2 13.4 GO:0060242 contact inhibition(GO:0060242)
2.2 6.6 GO:0072717 cellular response to actinomycin D(GO:0072717)
2.2 6.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
2.1 6.3 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
2.1 12.5 GO:0043504 mitochondrial DNA repair(GO:0043504)
2.1 14.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
2.1 6.2 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
2.1 6.2 GO:0036166 phenotypic switching(GO:0036166)
2.1 2.1 GO:0048254 snoRNA localization(GO:0048254)
2.0 10.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
2.0 6.0 GO:0018298 protein-chromophore linkage(GO:0018298)
2.0 6.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
2.0 8.0 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
1.9 1.9 GO:0035330 regulation of hippo signaling(GO:0035330)
1.9 3.8 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.9 5.7 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
1.9 5.7 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
1.9 3.8 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
1.9 7.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.9 11.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.8 14.5 GO:0040031 snRNA modification(GO:0040031)
1.8 10.8 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
1.8 21.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
1.8 1.8 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
1.7 5.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.7 10.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.7 12.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.7 8.6 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.7 8.6 GO:0006543 glutamine catabolic process(GO:0006543)
1.7 15.5 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
1.7 3.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
1.7 6.8 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
1.7 8.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.7 3.4 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.6 6.6 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.6 11.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.6 13.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.6 4.8 GO:0042908 xenobiotic transport(GO:0042908)
1.6 18.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
1.6 4.7 GO:0072049 comma-shaped body morphogenesis(GO:0072049)
1.5 4.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.5 6.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.5 16.4 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
1.5 20.9 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
1.5 14.9 GO:0006527 arginine catabolic process(GO:0006527)
1.5 5.9 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
1.4 4.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
1.4 5.8 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
1.4 4.3 GO:0019043 establishment of viral latency(GO:0019043)
1.4 4.3 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
1.4 9.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.4 4.2 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
1.4 2.8 GO:0097212 lysosomal membrane organization(GO:0097212)
1.4 2.8 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
1.4 2.7 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
1.4 6.8 GO:0043985 histone H4-R3 methylation(GO:0043985)
1.4 8.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
1.4 4.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
1.3 2.7 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.3 1.3 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.3 2.7 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
1.3 7.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
1.3 9.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
1.3 9.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.3 9.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
1.3 3.9 GO:0019346 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
1.3 6.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
1.3 12.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
1.3 1.3 GO:0043585 nose morphogenesis(GO:0043585)
1.2 3.7 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.2 4.9 GO:0042360 vitamin E metabolic process(GO:0042360)
1.2 3.6 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.2 3.6 GO:0045004 DNA replication proofreading(GO:0045004)
1.2 6.0 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
1.2 11.9 GO:0030322 stabilization of membrane potential(GO:0030322)
1.2 4.8 GO:0003360 brainstem development(GO:0003360)
1.2 2.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
1.2 3.6 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
1.2 17.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
1.2 4.7 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
1.2 1.2 GO:1904426 positive regulation of GTP binding(GO:1904426)
1.1 18.2 GO:0038092 nodal signaling pathway(GO:0038092)
1.1 3.4 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
1.1 4.5 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032)
1.1 7.9 GO:0051503 adenine nucleotide transport(GO:0051503)
1.1 4.5 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
1.1 6.7 GO:0044351 macropinocytosis(GO:0044351)
1.1 12.1 GO:0006105 succinate metabolic process(GO:0006105)
1.1 12.1 GO:0097154 GABAergic neuron differentiation(GO:0097154)
1.1 5.5 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.1 2.2 GO:0010424 DNA methylation on cytosine within a CG sequence(GO:0010424)
1.1 3.2 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
1.1 4.3 GO:0002326 B cell lineage commitment(GO:0002326)
1.0 3.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
1.0 3.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
1.0 18.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.0 2.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
1.0 3.9 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.9 2.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.9 1.9 GO:0006272 leading strand elongation(GO:0006272)
0.9 2.8 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.9 16.0 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.9 4.7 GO:0006167 AMP biosynthetic process(GO:0006167)
0.9 5.6 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.9 4.6 GO:0032439 endosome localization(GO:0032439)
0.9 6.3 GO:0080111 DNA demethylation(GO:0080111)
0.9 3.6 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.9 7.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.9 15.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.9 0.9 GO:0007525 somatic muscle development(GO:0007525)
0.9 4.5 GO:0006183 GTP biosynthetic process(GO:0006183)
0.9 43.4 GO:0006414 translational elongation(GO:0006414)
0.9 9.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.9 4.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.9 2.6 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.9 6.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.9 9.4 GO:0060539 diaphragm development(GO:0060539)
0.8 2.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.8 0.8 GO:0016078 tRNA catabolic process(GO:0016078)
0.8 4.2 GO:0015705 iodide transport(GO:0015705)
0.8 3.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.8 4.2 GO:0018158 protein oxidation(GO:0018158)
0.8 1.7 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.8 5.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.8 26.2 GO:0046677 response to antibiotic(GO:0046677)
0.8 2.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.8 3.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.8 15.3 GO:0006907 pinocytosis(GO:0006907)
0.8 5.5 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.8 3.1 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.8 24.2 GO:0048255 mRNA stabilization(GO:0048255)
0.8 10.8 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.8 1.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.8 2.3 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.8 1.5 GO:0034969 histone arginine methylation(GO:0034969)
0.8 5.3 GO:0046549 retinal cone cell development(GO:0046549)
0.8 3.0 GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209)
0.7 1.5 GO:0043096 purine nucleobase salvage(GO:0043096)
0.7 2.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.7 2.1 GO:0035973 aggrephagy(GO:0035973)
0.7 2.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.7 6.3 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.7 2.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.7 3.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.7 7.5 GO:0070986 left/right axis specification(GO:0070986)
0.7 2.7 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.7 4.1 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.7 0.7 GO:1903294 glutamate secretion, neurotransmission(GO:0061535) regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.7 4.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.7 1.3 GO:0001757 somite specification(GO:0001757)
0.7 2.6 GO:0030576 Cajal body organization(GO:0030576)
0.6 3.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.6 4.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.6 6.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.6 8.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.6 11.8 GO:0000154 rRNA modification(GO:0000154)
0.6 1.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.6 9.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.6 2.5 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.6 4.3 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.6 4.8 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.6 3.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.6 1.2 GO:0042637 catagen(GO:0042637)
0.6 4.8 GO:0032310 prostaglandin secretion(GO:0032310)
0.6 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.6 5.4 GO:0031424 keratinization(GO:0031424)
0.6 2.4 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.6 0.6 GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208)
0.6 6.6 GO:0006020 inositol metabolic process(GO:0006020)
0.6 2.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.6 2.4 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.6 4.1 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.6 4.7 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.6 2.4 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.6 4.1 GO:0007144 female meiosis I(GO:0007144)
0.6 1.7 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.6 1.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.6 6.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.6 3.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.6 4.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.6 1.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.6 2.3 GO:0072205 metanephric collecting duct development(GO:0072205)
0.6 1.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.6 1.7 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.6 5.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.6 2.2 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.6 2.2 GO:0046689 response to mercury ion(GO:0046689)
0.5 3.8 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.5 1.6 GO:2000510 regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.5 8.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.5 3.2 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.5 5.9 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.5 1.1 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.5 1.6 GO:0002922 positive regulation of humoral immune response(GO:0002922)
0.5 5.8 GO:0018126 protein hydroxylation(GO:0018126)
0.5 13.0 GO:1901984 negative regulation of protein acetylation(GO:1901984)
0.5 3.6 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.5 5.7 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.5 2.6 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.5 1.0 GO:0046098 regulation of primitive erythrocyte differentiation(GO:0010725) guanine metabolic process(GO:0046098)
0.5 6.7 GO:0006000 fructose metabolic process(GO:0006000)
0.5 2.1 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.5 1.0 GO:0006382 adenosine to inosine editing(GO:0006382) base conversion or substitution editing(GO:0016553)
0.5 2.0 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.5 2.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.5 5.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 3.0 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.5 7.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.5 6.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.5 2.0 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.5 2.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.5 2.0 GO:0036089 cleavage furrow formation(GO:0036089)
0.5 3.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.5 7.8 GO:0000338 protein deneddylation(GO:0000338)
0.5 5.3 GO:0031639 plasminogen activation(GO:0031639)
0.5 6.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.5 3.4 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.5 7.1 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.5 5.2 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.5 1.9 GO:0031133 regulation of axon diameter(GO:0031133)
0.5 3.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.5 3.7 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235)
0.5 3.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.5 5.1 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.5 1.9 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.5 12.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.5 9.1 GO:0003416 endochondral bone growth(GO:0003416)
0.5 7.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 1.8 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.5 21.7 GO:0016925 protein sumoylation(GO:0016925)
0.5 2.7 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.4 3.6 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.4 1.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.4 2.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 1.7 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.4 1.3 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.4 1.7 GO:0006014 D-ribose metabolic process(GO:0006014)
0.4 1.3 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608) regulation of testosterone biosynthetic process(GO:2000224)
0.4 2.1 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) dATP metabolic process(GO:0046060)
0.4 1.3 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.4 1.3 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.4 3.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 1.7 GO:0018343 protein farnesylation(GO:0018343)
0.4 1.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.4 1.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.4 3.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.4 0.4 GO:0001771 immunological synapse formation(GO:0001771)
0.4 3.5 GO:0038203 TORC2 signaling(GO:0038203)
0.4 8.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.4 5.8 GO:0051451 myoblast migration(GO:0051451)
0.4 4.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 1.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.4 6.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.4 2.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 1.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.4 15.5 GO:0006400 tRNA modification(GO:0006400)
0.4 11.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 8.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.4 0.8 GO:0006526 arginine biosynthetic process(GO:0006526)
0.4 1.1 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.4 0.4 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
0.4 1.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.4 1.5 GO:0036035 osteoclast development(GO:0036035) bone cell development(GO:0098751)
0.4 2.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 1.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.4 1.8 GO:1903232 melanosome assembly(GO:1903232)
0.4 1.1 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) lateral motor column neuron migration(GO:0097477)
0.4 5.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 1.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.4 5.3 GO:0042407 cristae formation(GO:0042407)
0.4 1.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 2.4 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.3 1.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.3 2.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.3 3.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.3 7.1 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.3 3.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 2.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.3 11.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 1.0 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
0.3 7.3 GO:0009303 rRNA transcription(GO:0009303)
0.3 2.0 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.3 1.0 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.3 0.7 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.3 1.6 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.3 4.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.3 1.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3 1.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 1.0 GO:1990859 cellular response to endothelin(GO:1990859)
0.3 3.5 GO:0048484 enteric nervous system development(GO:0048484)
0.3 2.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 1.6 GO:0060192 negative regulation of lipase activity(GO:0060192)
0.3 1.6 GO:0044854 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.3 2.2 GO:0001842 neural fold formation(GO:0001842)
0.3 0.9 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.3 3.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.3 2.8 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.3 1.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 0.9 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.3 1.8 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 7.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.3 1.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.3 1.5 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.3 0.3 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.3 1.7 GO:0006528 asparagine metabolic process(GO:0006528)
0.3 1.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.3 5.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.3 4.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 1.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.3 5.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.3 7.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.3 1.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.3 1.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 8.3 GO:0043966 histone H3 acetylation(GO:0043966)
0.3 2.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.3 1.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.3 2.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 0.5 GO:1903416 response to glycoside(GO:1903416)
0.3 0.8 GO:0014744 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of muscle adaptation(GO:0014744) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.3 4.3 GO:0003334 keratinocyte development(GO:0003334)
0.3 0.8 GO:0030656 regulation of vitamin metabolic process(GO:0030656)
0.3 1.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 0.8 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 1.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.3 1.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.3 1.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 4.2 GO:0016486 peptide hormone processing(GO:0016486)
0.3 1.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 6.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 3.6 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.3 0.5 GO:0032493 response to bacterial lipoprotein(GO:0032493)
0.3 1.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.3 1.0 GO:0060056 mammary gland involution(GO:0060056)
0.3 1.3 GO:0036499 PERK-mediated unfolded protein response(GO:0036499)
0.3 1.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.3 1.8 GO:0006273 lagging strand elongation(GO:0006273)
0.3 3.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.3 1.0 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.2 0.7 GO:0070459 prolactin secretion(GO:0070459)
0.2 3.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 3.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 2.5 GO:0003338 metanephros morphogenesis(GO:0003338)
0.2 0.7 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 3.2 GO:2000191 regulation of fatty acid transport(GO:2000191)
0.2 0.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.2 1.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 0.2 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.2 0.5 GO:0042414 epinephrine metabolic process(GO:0042414)
0.2 5.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 0.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 2.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 0.5 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 2.6 GO:0030497 fatty acid elongation(GO:0030497)
0.2 0.9 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 4.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.2 4.4 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.2 0.2 GO:0009109 coenzyme catabolic process(GO:0009109)
0.2 2.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2 0.7 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.2 0.9 GO:0015888 thiamine transport(GO:0015888)
0.2 1.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 5.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 1.1 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.2 0.9 GO:0031047 gene silencing by RNA(GO:0031047)
0.2 1.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.2 0.7 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.2 1.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 2.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 6.5 GO:0006270 DNA replication initiation(GO:0006270)
0.2 2.1 GO:0046033 AMP metabolic process(GO:0046033)
0.2 3.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.2 1.6 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 2.4 GO:0032309 icosanoid secretion(GO:0032309)
0.2 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.2 1.6 GO:0032494 response to peptidoglycan(GO:0032494)
0.2 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.6 GO:2000736 regulation of stem cell differentiation(GO:2000736)
0.2 1.4 GO:0019388 galactose catabolic process(GO:0019388)
0.2 0.6 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 0.8 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.2 0.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 1.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 0.6 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 6.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 2.7 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.2 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.2 0.6 GO:0061743 motor learning(GO:0061743)
0.2 1.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 2.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 1.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 11.2 GO:0001942 hair follicle development(GO:0001942) skin epidermis development(GO:0098773)
0.2 0.6 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359)
0.2 8.0 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 3.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 3.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 1.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.2 1.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 1.4 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.2 9.7 GO:0051028 mRNA transport(GO:0051028)
0.2 0.5 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 2.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 1.0 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 9.0 GO:0051298 centrosome duplication(GO:0051298)
0.2 2.6 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.2 3.8 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 1.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 5.1 GO:0006739 NADP metabolic process(GO:0006739)
0.2 0.5 GO:0001828 inner cell mass cell differentiation(GO:0001826) inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.2 0.7 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.2 3.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 1.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 4.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.2 0.2 GO:0018208 peptidyl-proline modification(GO:0018208)
0.2 0.7 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.2 1.1 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 2.2 GO:0044458 motile cilium assembly(GO:0044458)
0.2 0.8 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.2 1.1 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.2 1.9 GO:0043248 proteasome assembly(GO:0043248)
0.2 2.2 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.2 5.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 0.5 GO:0072683 T cell extravasation(GO:0072683)
0.2 4.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.7 GO:0021924 cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.2 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.8 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.2 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 2.1 GO:0046039 GTP metabolic process(GO:0046039)
0.1 5.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 1.6 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 4.2 GO:0051310 metaphase plate congression(GO:0051310)
0.1 14.7 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 2.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 2.7 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 6.7 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 1.4 GO:0030238 male sex determination(GO:0030238)
0.1 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.3 GO:0034123 positive regulation of toll-like receptor signaling pathway(GO:0034123)
0.1 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 8.3 GO:0006413 translational initiation(GO:0006413)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 4.7 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 5.9 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.3 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 1.1 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.8 GO:0002544 chronic inflammatory response(GO:0002544)
0.1 1.4 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 1.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 1.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.1 1.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 6.0 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.1 0.5 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.5 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.9 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.1 0.5 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.3 GO:0006706 steroid catabolic process(GO:0006706)
0.1 6.8 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.1 1.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.5 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 1.3 GO:0043486 histone exchange(GO:0043486)
0.1 2.0 GO:0031648 protein destabilization(GO:0031648)
0.1 0.8 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.6 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 3.9 GO:0051693 actin filament capping(GO:0051693)
0.1 0.8 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.8 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.3 GO:0060290 transdifferentiation(GO:0060290)
0.1 0.8 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.3 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.2 GO:0043489 RNA stabilization(GO:0043489)
0.1 1.3 GO:0021670 lateral ventricle development(GO:0021670)
0.1 1.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 6.1 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.1 1.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 3.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 7.1 GO:0006457 protein folding(GO:0006457)
0.1 0.5 GO:0072553 terminal button organization(GO:0072553)
0.1 0.6 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.3 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.1 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:0050892 intestinal absorption(GO:0050892)
0.1 2.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.3 GO:0015886 heme transport(GO:0015886)
0.1 0.2 GO:0002934 desmosome organization(GO:0002934)
0.1 0.5 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.6 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 0.3 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.5 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.1 0.6 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 1.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.5 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.1 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 3.4 GO:0007043 cell-cell junction assembly(GO:0007043)
0.1 0.9 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.1 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.1 1.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.6 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 1.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.1 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.1 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 1.4 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 3.8 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 0.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.5 GO:0006213 pyrimidine nucleoside metabolic process(GO:0006213)
0.1 1.4 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.1 0.4 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.1 0.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.3 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.5 GO:0016556 mRNA modification(GO:0016556)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.9 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.1 1.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.1 0.2 GO:0006415 translational termination(GO:0006415)
0.0 1.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.2 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.5 GO:0044243 multicellular organism catabolic process(GO:0044243)
0.0 0.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.7 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 1.0 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 1.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0007127 meiosis I(GO:0007127)
0.0 1.4 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.8 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 0.1 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.0 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.5 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0048144 fibroblast proliferation(GO:0048144)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0097501 stress response to metal ion(GO:0097501)
0.0 0.1 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.1 GO:2000648 positive regulation of stem cell proliferation(GO:2000648)
0.0 0.0 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 28.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
5.0 29.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
4.5 13.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
4.1 36.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
3.2 9.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
3.2 35.2 GO:0005642 annulate lamellae(GO:0005642)
2.6 18.3 GO:0097422 tubular endosome(GO:0097422)
2.5 9.8 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
2.4 12.2 GO:0032133 chromosome passenger complex(GO:0032133)
2.3 16.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
2.1 12.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
2.0 10.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
2.0 6.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.9 7.6 GO:0008537 proteasome activator complex(GO:0008537)
1.9 11.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.8 11.0 GO:0000125 PCAF complex(GO:0000125)
1.8 25.3 GO:0035686 sperm fibrous sheath(GO:0035686)
1.8 7.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.7 7.0 GO:0001651 dense fibrillar component(GO:0001651)
1.7 5.2 GO:0031088 platelet dense granule membrane(GO:0031088)
1.6 4.8 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.6 3.2 GO:0044391 ribosomal subunit(GO:0044391)
1.6 33.0 GO:0031527 filopodium membrane(GO:0031527)
1.5 9.0 GO:0034448 EGO complex(GO:0034448)
1.5 25.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
1.4 12.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.4 4.1 GO:0044194 cytolytic granule(GO:0044194)
1.3 8.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
1.3 8.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.3 17.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
1.3 6.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
1.3 6.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
1.3 6.5 GO:0030314 junctional membrane complex(GO:0030314)
1.3 6.5 GO:0005826 actomyosin contractile ring(GO:0005826)
1.3 3.9 GO:0033186 CAF-1 complex(GO:0033186)
1.3 3.8 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
1.3 3.8 GO:0005577 fibrinogen complex(GO:0005577)
1.3 7.6 GO:0033010 paranodal junction(GO:0033010)
1.3 5.0 GO:0001674 female germ cell nucleus(GO:0001674)
1.2 3.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.2 5.8 GO:0043527 tRNA methyltransferase complex(GO:0043527)
1.1 11.5 GO:0070545 PeBoW complex(GO:0070545)
1.1 3.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
1.1 3.4 GO:0000799 nuclear condensin complex(GO:0000799)
1.1 4.5 GO:0043293 apoptosome(GO:0043293)
1.1 5.5 GO:0035189 Rb-E2F complex(GO:0035189)
1.1 5.4 GO:0044611 nuclear pore inner ring(GO:0044611)
1.1 11.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.0 1.0 GO:0070761 pre-snoRNP complex(GO:0070761)
1.0 2.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.9 4.7 GO:0001533 cornified envelope(GO:0001533)
0.9 6.5 GO:0005775 vacuolar lumen(GO:0005775)
0.9 48.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.9 2.6 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.8 11.9 GO:0005922 connexon complex(GO:0005922)
0.8 6.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.8 6.6 GO:0031415 NatA complex(GO:0031415)
0.8 5.7 GO:0001740 Barr body(GO:0001740)
0.8 3.3 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.8 2.4 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.8 2.4 GO:0000811 GINS complex(GO:0000811)
0.8 17.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.8 4.6 GO:0071986 Ragulator complex(GO:0071986)
0.8 3.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.7 4.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.7 7.4 GO:0046930 pore complex(GO:0046930)
0.7 4.4 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.7 2.2 GO:0000801 central element(GO:0000801)
0.7 37.5 GO:0000791 euchromatin(GO:0000791)
0.7 32.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.7 2.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.7 3.4 GO:0033391 chromatoid body(GO:0033391)
0.7 6.8 GO:0034709 methylosome(GO:0034709)
0.7 5.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.6 9.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.6 1.9 GO:0097543 ciliary inversin compartment(GO:0097543)
0.6 12.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.6 50.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.6 4.2 GO:0097413 Lewy body(GO:0097413)
0.6 5.3 GO:0061617 MICOS complex(GO:0061617)
0.6 1.8 GO:0005899 insulin receptor complex(GO:0005899)
0.6 2.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.6 9.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.6 5.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.6 7.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 5.0 GO:0001939 female pronucleus(GO:0001939)
0.6 5.0 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.6 3.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.5 1.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5 11.3 GO:0016580 Sin3 complex(GO:0016580)
0.5 8.5 GO:0030914 STAGA complex(GO:0030914)
0.5 3.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.5 6.7 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.5 2.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.5 2.0 GO:0045179 apical cortex(GO:0045179)
0.5 3.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.5 2.9 GO:1990393 3M complex(GO:1990393)
0.5 5.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.5 13.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.5 5.0 GO:0005915 zonula adherens(GO:0005915)
0.5 4.1 GO:0045120 pronucleus(GO:0045120)
0.4 2.7 GO:0097443 sorting endosome(GO:0097443)
0.4 1.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.4 5.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.4 28.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.4 1.3 GO:0000502 proteasome complex(GO:0000502)
0.4 2.5 GO:0030870 Mre11 complex(GO:0030870)
0.4 2.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 1.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.4 3.7 GO:0042587 glycogen granule(GO:0042587)
0.4 1.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.4 3.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 18.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 6.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.4 6.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 2.7 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.4 6.9 GO:0030686 90S preribosome(GO:0030686)
0.4 3.0 GO:0005682 U5 snRNP(GO:0005682)
0.4 1.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.4 2.7 GO:0000796 condensin complex(GO:0000796)
0.4 5.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.4 1.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 2.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.4 2.2 GO:0097255 R2TP complex(GO:0097255)
0.4 5.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.4 2.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.4 4.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 5.7 GO:0035102 PRC1 complex(GO:0035102)
0.3 4.5 GO:0097542 ciliary tip(GO:0097542)
0.3 7.3 GO:0038201 TOR complex(GO:0038201)
0.3 8.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 4.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.7 GO:0072487 MSL complex(GO:0072487)
0.3 3.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 1.4 GO:0043511 inhibin complex(GO:0043511)
0.3 2.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.3 0.9 GO:0035101 FACT complex(GO:0035101)
0.3 18.0 GO:0072686 mitotic spindle(GO:0072686)
0.3 4.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 3.4 GO:0031528 microvillus membrane(GO:0031528)
0.3 1.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3 1.2 GO:0071942 XPC complex(GO:0071942)
0.3 6.2 GO:0035253 ciliary rootlet(GO:0035253)
0.3 3.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 2.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 14.2 GO:0005844 polysome(GO:0005844)
0.3 11.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 1.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.3 2.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 1.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 1.3 GO:1990357 terminal web(GO:1990357)
0.3 1.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 3.4 GO:0042555 MCM complex(GO:0042555)
0.3 3.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.3 2.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 1.0 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 17.5 GO:0005581 collagen trimer(GO:0005581)
0.2 1.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 1.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 0.5 GO:0044299 C-fiber(GO:0044299)
0.2 10.7 GO:0005882 intermediate filament(GO:0005882)
0.2 10.7 GO:0005657 replication fork(GO:0005657)
0.2 19.1 GO:0016363 nuclear matrix(GO:0016363)
0.2 1.3 GO:0005859 muscle myosin complex(GO:0005859)
0.2 3.1 GO:0005871 kinesin complex(GO:0005871)
0.2 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 6.2 GO:0030904 retromer complex(GO:0030904)
0.2 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 0.8 GO:0032280 symmetric synapse(GO:0032280)
0.2 7.8 GO:0008180 COP9 signalosome(GO:0008180)
0.2 1.0 GO:0031970 organelle envelope lumen(GO:0031970)
0.2 47.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 1.8 GO:0016272 prefoldin complex(GO:0016272)
0.2 1.2 GO:0097342 ripoptosome(GO:0097342)
0.2 0.8 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 1.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 23.2 GO:0001650 fibrillar center(GO:0001650)
0.2 0.2 GO:1902737 dendritic filopodium(GO:1902737)
0.2 7.2 GO:0016235 aggresome(GO:0016235)
0.2 66.1 GO:0005925 focal adhesion(GO:0005925)
0.2 4.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 1.1 GO:0000974 Prp19 complex(GO:0000974)
0.2 1.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 5.1 GO:0005876 spindle microtubule(GO:0005876)
0.2 3.3 GO:0015030 Cajal body(GO:0015030)
0.2 0.9 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 11.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.6 GO:0097447 dendritic tree(GO:0097447)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 7.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.4 GO:0034399 nuclear periphery(GO:0034399)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.6 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 6.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 1.1 GO:0061574 ASAP complex(GO:0061574)
0.1 5.9 GO:0005901 caveola(GO:0005901)
0.1 8.2 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.8 GO:0036038 MKS complex(GO:0036038)
0.1 1.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 6.0 GO:0005643 nuclear pore(GO:0005643)
0.1 0.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.2 GO:0034464 BBSome(GO:0034464)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 9.3 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 6.4 GO:0000786 nucleosome(GO:0000786)
0.1 5.3 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.1 6.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 125.9 GO:0005739 mitochondrion(GO:0005739)
0.1 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.9 GO:0044452 nucleolar part(GO:0044452)
0.1 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.9 GO:0031902 late endosome membrane(GO:0031902)
0.1 14.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 6.1 GO:0043209 myelin sheath(GO:0043209)
0.1 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.4 GO:0030478 actin cap(GO:0030478)
0.1 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.3 GO:0016592 mediator complex(GO:0016592)
0.1 113.2 GO:0005576 extracellular region(GO:0005576)
0.0 1.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 1.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.7 GO:0031514 motile cilium(GO:0031514)
0.0 0.9 GO:0005903 brush border(GO:0005903)
0.0 9.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 8.3 GO:0016604 nuclear body(GO:0016604)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.0 GO:0000172 ribonuclease MRP complex(GO:0000172)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
9.1 27.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
6.7 20.0 GO:0035939 microsatellite binding(GO:0035939)
6.3 25.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
5.2 20.9 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
4.9 14.6 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
4.7 14.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
3.8 15.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
3.7 40.2 GO:0015250 water channel activity(GO:0015250)
3.5 14.2 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
3.4 13.7 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
3.2 19.4 GO:0043426 MRF binding(GO:0043426)
3.2 9.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
3.2 12.7 GO:0004832 valine-tRNA ligase activity(GO:0004832)
2.9 70.0 GO:0003746 translation elongation factor activity(GO:0003746)
2.9 17.5 GO:0001069 regulatory region RNA binding(GO:0001069)
2.9 11.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
2.9 8.7 GO:0004774 succinate-CoA ligase activity(GO:0004774)
2.8 8.3 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
2.4 17.0 GO:0034452 dynactin binding(GO:0034452)
2.4 14.2 GO:1990932 5.8S rRNA binding(GO:1990932)
2.4 9.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
2.3 6.8 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
2.2 13.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
2.1 6.3 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
2.0 6.0 GO:0009881 photoreceptor activity(GO:0009881)
1.9 13.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.9 9.5 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
1.9 9.4 GO:0019238 cyclohydrolase activity(GO:0019238)
1.9 7.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
1.8 12.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.7 20.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
1.6 6.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.6 6.5 GO:0031687 A2A adenosine receptor binding(GO:0031687)
1.6 6.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
1.6 8.0 GO:0004565 beta-galactosidase activity(GO:0004565)
1.6 28.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
1.6 4.7 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
1.5 4.6 GO:0004335 galactokinase activity(GO:0004335)
1.5 9.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.5 4.5 GO:0031403 lithium ion binding(GO:0031403)
1.5 4.4 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
1.5 16.1 GO:0015245 fatty acid transporter activity(GO:0015245)
1.4 8.5 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
1.4 9.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.4 25.7 GO:0051920 peroxiredoxin activity(GO:0051920)
1.3 5.3 GO:0004046 aminoacylase activity(GO:0004046)
1.3 6.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
1.3 5.2 GO:0035174 histone serine kinase activity(GO:0035174)
1.3 7.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.3 5.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.3 3.8 GO:0070052 collagen V binding(GO:0070052)
1.3 3.8 GO:0098809 nitrite reductase activity(GO:0098809)
1.3 6.3 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.3 5.0 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.2 3.7 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.2 9.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.2 9.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.2 28.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.2 2.4 GO:0031493 nucleosomal histone binding(GO:0031493)
1.2 3.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
1.2 9.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.2 4.8 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
1.2 3.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
1.2 6.0 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.2 8.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
1.2 8.1 GO:0043559 insulin binding(GO:0043559)
1.1 3.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.1 9.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.1 4.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.1 1.1 GO:0003681 bent DNA binding(GO:0003681)
1.1 2.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.1 3.3 GO:0016015 morphogen activity(GO:0016015)
1.1 15.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.1 3.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
1.1 4.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
1.1 8.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.1 4.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.0 9.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.0 2.1 GO:0034046 poly(G) binding(GO:0034046)
1.0 15.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
1.0 3.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
1.0 6.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.0 5.0 GO:0008097 5S rRNA binding(GO:0008097)
1.0 7.9 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
1.0 5.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.0 4.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
1.0 10.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
1.0 2.9 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
1.0 46.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.0 2.9 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
1.0 7.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.9 7.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.9 2.8 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.9 3.7 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.9 2.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.9 8.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.9 2.7 GO:0038132 neuregulin binding(GO:0038132)
0.9 4.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.9 18.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.9 7.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.9 2.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.9 10.6 GO:0031386 protein tag(GO:0031386)
0.9 2.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.9 5.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.8 4.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.8 1.7 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.8 12.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.8 7.4 GO:0051434 BH3 domain binding(GO:0051434)
0.8 14.7 GO:0043121 neurotrophin binding(GO:0043121)
0.8 4.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.8 7.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.8 4.8 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.8 7.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.8 2.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.8 17.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.8 3.0 GO:0003883 CTP synthase activity(GO:0003883)
0.8 3.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.8 29.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.8 2.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.7 2.9 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 9.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.7 15.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.7 14.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.7 19.2 GO:0008432 JUN kinase binding(GO:0008432)
0.7 2.8 GO:0030984 kininogen binding(GO:0030984)
0.7 2.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.7 32.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.7 27.5 GO:0045182 translation regulator activity(GO:0045182)
0.7 1.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.7 11.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.7 3.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.7 3.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.7 2.7 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.6 10.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.6 6.4 GO:0001618 virus receptor activity(GO:0001618)
0.6 10.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.6 1.9 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.6 1.9 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.6 1.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.6 8.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.6 2.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.6 3.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.6 1.8 GO:0035242 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.6 0.6 GO:0031893 vasopressin receptor binding(GO:0031893)
0.6 5.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.6 1.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.6 6.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.6 0.6 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.6 3.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 3.4 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.6 2.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.6 5.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 10.6 GO:0008483 transaminase activity(GO:0008483)
0.6 2.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.5 5.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.5 1.6 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.5 1.6 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.5 4.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.5 2.7 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.5 6.3 GO:0070097 delta-catenin binding(GO:0070097)
0.5 7.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.5 17.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.5 1.6 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.5 4.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 9.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.5 10.8 GO:0070064 proline-rich region binding(GO:0070064)
0.5 4.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.5 3.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.5 1.5 GO:0002060 purine nucleobase binding(GO:0002060)
0.5 1.9 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.5 3.9 GO:0039706 co-receptor binding(GO:0039706)
0.5 3.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.5 2.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.5 74.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.5 2.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.4 2.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 3.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.4 3.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.4 9.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.4 1.7 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.4 2.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.4 14.8 GO:0005109 frizzled binding(GO:0005109)
0.4 1.3 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 4.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.4 14.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.4 1.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.4 5.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.4 1.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.4 3.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 1.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.4 4.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.4 1.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.4 1.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.4 13.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 7.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 15.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 3.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.4 1.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.4 1.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.4 16.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.4 2.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 22.2 GO:0019955 cytokine binding(GO:0019955)
0.4 1.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 3.5 GO:0005522 profilin binding(GO:0005522)
0.4 6.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 3.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 1.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 1.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 7.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 1.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.3 1.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 3.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 1.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 1.3 GO:0004126 cytidine deaminase activity(GO:0004126) pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.9 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 1.9 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.3 6.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 0.6 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.3 1.8 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.3 2.2 GO:0008430 selenium binding(GO:0008430)
0.3 7.9 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.3 0.9 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.3 17.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 1.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 8.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 1.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 1.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 2.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 0.8 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 4.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 1.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.3 11.1 GO:0003678 DNA helicase activity(GO:0003678)
0.3 5.7 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.3 2.7 GO:0015266 protein channel activity(GO:0015266)
0.3 1.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.3 1.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 5.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.3 6.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.3 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 8.5 GO:0016504 peptidase activator activity(GO:0016504)
0.3 5.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.7 GO:0008242 omega peptidase activity(GO:0008242)
0.2 0.7 GO:0051425 PTB domain binding(GO:0051425)
0.2 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 7.1 GO:0008009 chemokine activity(GO:0008009)
0.2 1.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 2.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 1.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 1.7 GO:0001515 opioid peptide activity(GO:0001515)
0.2 0.5 GO:0004645 phosphorylase activity(GO:0004645)
0.2 0.7 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 4.8 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 4.7 GO:0019843 rRNA binding(GO:0019843)
0.2 1.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 5.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 2.0 GO:0000182 rDNA binding(GO:0000182)
0.2 13.7 GO:0051082 unfolded protein binding(GO:0051082)
0.2 0.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 3.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.2 1.2 GO:0042301 phosphate ion binding(GO:0042301)
0.2 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 7.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 2.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 0.4 GO:0030519 snoRNP binding(GO:0030519)
0.2 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 3.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 2.8 GO:0030515 snoRNA binding(GO:0030515)
0.2 3.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 1.4 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 2.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 30.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 1.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 8.9 GO:0005125 cytokine activity(GO:0005125)
0.2 0.5 GO:0034618 arginine binding(GO:0034618)
0.2 3.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 0.7 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 3.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 2.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 0.8 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.2 1.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 1.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 0.8 GO:0034235 GPI anchor binding(GO:0034235)
0.2 0.8 GO:0000339 RNA cap binding(GO:0000339)
0.2 2.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 0.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 3.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.2 0.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 3.5 GO:0017046 peptide hormone binding(GO:0017046)
0.2 4.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 2.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.2 0.9 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 13.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 1.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.8 GO:0017166 vinculin binding(GO:0017166)
0.1 1.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.9 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 9.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 7.5 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 7.7 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.7 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 6.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 2.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 3.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 2.0 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 6.0 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 2.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.0 GO:0001968 fibronectin binding(GO:0001968)
0.1 2.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 18.2 GO:0001047 core promoter binding(GO:0001047)
0.1 1.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 4.7 GO:0005507 copper ion binding(GO:0005507)
0.1 4.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 4.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 2.7 GO:0097602 cullin family protein binding(GO:0097602)
0.1 4.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 4.3 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 2.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.3 GO:0070628 proteasome binding(GO:0070628)
0.1 1.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 1.1 GO:0032183 SUMO binding(GO:0032183)
0.1 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.7 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.4 GO:0004103 choline kinase activity(GO:0004103)
0.1 2.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.9 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 5.0 GO:0008565 protein transporter activity(GO:0008565)
0.1 2.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 3.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 2.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.6 GO:0004527 exonuclease activity(GO:0004527)
0.1 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.8 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 2.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 1.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0004497 monooxygenase activity(GO:0004497)
0.1 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 7.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 3.6 GO:0008168 methyltransferase activity(GO:0008168)
0.1 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 9.6 GO:0045296 cadherin binding(GO:0045296)
0.0 3.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 49.0 GO:0003723 RNA binding(GO:0003723)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391)
0.0 0.4 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 1.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0048029 monosaccharide binding(GO:0048029)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 48.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.7 1.7 PID_S1P_S1P2_PATHWAY S1P2 pathway
1.3 154.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
1.0 30.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.7 21.6 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.7 6.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.7 26.4 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.7 54.4 PID_INSULIN_PATHWAY Insulin Pathway
0.6 17.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.6 10.3 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 15.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.6 4.7 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6 3.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 9.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.5 5.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.5 17.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.5 19.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.5 10.6 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.4 22.2 PID_BMP_PATHWAY BMP receptor signaling
0.4 3.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.4 2.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.4 28.2 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.3 16.8 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.3 2.9 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.3 9.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.3 6.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.3 11.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 11.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.3 11.0 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.3 3.9 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.3 3.1 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.3 4.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.3 3.8 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 9.5 PID_CMYB_PATHWAY C-MYB transcription factor network
0.2 3.6 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 15.9 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 0.9 PID_ALK2_PATHWAY ALK2 signaling events
0.2 4.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 23.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 2.9 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 6.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.2 6.4 PID_IL12_2PATHWAY IL12-mediated signaling events
0.2 3.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 0.9 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 3.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.3 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 2.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 6.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 3.2 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.4 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 3.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 3.2 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 2.0 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 4.3 PID_E2F_PATHWAY E2F transcription factor network
0.1 2.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.1 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.1 0.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 2.0 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.1 0.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 3.2 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 1.7 PID_BARD1_PATHWAY BARD1 signaling events
0.1 3.6 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.8 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 4.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.0 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 3.1 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 1.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 3.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.1 2.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 1.1 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.5 PID_ALK1_PATHWAY ALK1 signaling events
0.1 0.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 5.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.1 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 SIG_CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 34.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.7 35.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
1.6 35.8 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
1.6 26.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
1.5 24.7 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
1.4 12.7 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.3 61.5 REACTOME_G1_PHASE Genes involved in G1 Phase
1.3 21.0 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
1.3 33.9 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
1.2 12.5 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.2 16.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.1 63.7 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
1.0 15.9 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
1.0 11.6 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
1.0 6.8 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
1.0 16.4 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.9 48.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.9 24.3 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.8 14.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.7 21.0 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.7 7.8 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.7 7.0 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.7 20.0 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.7 43.2 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.7 5.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.7 16.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.7 2.6 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.7 16.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.6 12.2 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.6 6.1 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.6 6.0 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.6 11.9 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.6 7.0 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.5 12.0 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.5 18.4 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.5 48.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.5 7.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.5 4.6 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.5 11.0 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5 4.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.5 9.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.5 4.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.5 7.2 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.5 6.0 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.5 4.6 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 21.1 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.4 7.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 3.5 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.4 6.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 18.5 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.4 28.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.4 21.2 REACTOME_TRANSLATION Genes involved in Translation
0.4 7.5 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.4 4.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.4 15.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 2.6 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 2.2 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.4 33.1 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.4 5.8 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.4 8.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 2.4 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.3 1.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.3 27.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.3 4.6 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.3 4.9 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.3 2.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 17.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.3 6.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 11.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 7.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.3 2.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.3 9.9 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 1.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.3 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 13.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3 7.6 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3 2.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 1.9 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.2 13.6 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 4.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 2.0 REACTOME_GLOBAL_GENOMIC_NER_GG_NER Genes involved in Global Genomic NER (GG-NER)
0.2 4.1 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 2.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 5.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 1.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 1.6 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.2 6.6 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 0.9 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 3.8 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 2.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 10.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.2 12.2 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 0.8 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 1.4 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.2 1.8 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.2 4.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 3.4 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.2 4.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 1.5 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.2 4.8 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 1.7 REACTOME_REGULATION_OF_APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 1.0 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 3.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.8 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 0.5 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 7.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 3.9 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 5.3 REACTOME_DIABETES_PATHWAYS Genes involved in Diabetes pathways
0.1 1.2 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.0 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 2.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 0.6 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 19.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.0 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.7 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.1 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ Genes involved in Cyclin E associated events during G1/S transition
0.1 1.2 REACTOME_KINESINS Genes involved in Kinesins
0.1 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.3 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.1 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR