Motif ID: Mbd2

Z-value: 1.072


Transcription factors associated with Mbd2:

Gene SymbolEntrez IDGene Name
Mbd2 ENSMUSG00000024513.10 Mbd2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mbd2mm10_v2_chr18_+_70568189_70568398-0.181.8e-01Click!


Activity profile for motif Mbd2.

activity profile for motif Mbd2


Sorted Z-values histogram for motif Mbd2

Sorted Z-values for motif Mbd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mbd2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_108003414 8.633 ENSMUST00000109887.1
ENSMUST00000109891.2
Bcl11b

B cell leukemia/lymphoma 11B

chr5_+_30588078 7.739 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr11_-_75796048 6.392 ENSMUST00000021209.7
Doc2b
double C2, beta
chr14_-_39472825 5.965 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3


neuregulin 3


chr5_+_37028329 5.642 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr4_-_120747248 5.623 ENSMUST00000030376.7
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr1_+_75375271 5.483 ENSMUST00000087122.5
Speg
SPEG complex locus
chr6_-_126740151 4.750 ENSMUST00000112242.1
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr18_-_58209926 4.726 ENSMUST00000025497.6
Fbn2
fibrillin 2
chr19_+_56722372 4.651 ENSMUST00000038949.4
Adrb1
adrenergic receptor, beta 1
chr13_+_110395041 4.624 ENSMUST00000022212.7
Plk2
polo-like kinase 2
chr13_+_46418266 4.471 ENSMUST00000037923.3
Rbm24
RNA binding motif protein 24
chr5_+_36868467 4.452 ENSMUST00000031003.7
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr11_+_7063423 4.268 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr15_-_28025834 4.040 ENSMUST00000090247.5
Trio
triple functional domain (PTPRF interacting)
chr10_+_13966268 3.761 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr9_-_51008936 3.640 ENSMUST00000176824.1
ENSMUST00000176663.1
ENSMUST00000041375.10
Sik2


salt inducible kinase 2


chr11_+_104231573 3.583 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr13_-_52981027 3.579 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr7_-_126082406 3.537 ENSMUST00000073935.5
Gsg1l
GSG1-like
chrX_+_152144240 3.454 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
Iqsec2


IQ motif and Sec7 domain 2


chr11_+_104231515 3.452 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr11_+_104231465 3.420 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr7_+_29303938 3.418 ENSMUST00000108231.1
Dpf1
D4, zinc and double PHD fingers family 1
chr11_-_102296618 3.311 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr7_+_29303958 3.284 ENSMUST00000049977.6
Dpf1
D4, zinc and double PHD fingers family 1
chr4_+_155734800 3.250 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr5_-_115194283 3.229 ENSMUST00000112113.1
Cabp1
calcium binding protein 1
chr9_+_95559817 3.168 ENSMUST00000079597.5
Paqr9
progestin and adipoQ receptor family member IX
chr12_-_79007276 2.961 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr11_+_104231390 2.910 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr9_-_108190352 2.886 ENSMUST00000035208.7
Bsn
bassoon
chr12_-_108003594 2.882 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr7_-_74554474 2.849 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr9_+_26733845 2.790 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr14_-_55116935 2.753 ENSMUST00000022819.5
Jph4
junctophilin 4
chr1_+_74854954 2.644 ENSMUST00000160379.2
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr18_-_43393346 2.584 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr11_+_57645417 2.534 ENSMUST00000066987.7
ENSMUST00000108846.1
Galnt10

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10

chr2_-_24763047 2.533 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr14_-_68124836 2.346 ENSMUST00000111089.1
ENSMUST00000022638.5
Nefm

neurofilament, medium polypeptide

chr2_+_35622160 2.327 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr4_+_133039482 2.319 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr9_+_26733728 2.188 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr4_-_155345696 2.178 ENSMUST00000103178.4
Prkcz
protein kinase C, zeta
chr4_-_126753372 2.085 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr2_+_35622010 2.053 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr1_+_89454769 2.028 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr15_-_75566811 2.023 ENSMUST00000065417.8
Ly6h
lymphocyte antigen 6 complex, locus H
chr15_-_73645665 2.021 ENSMUST00000130765.1
Slc45a4
solute carrier family 45, member 4
chr7_+_19176416 1.954 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr8_+_27085520 1.937 ENSMUST00000178514.1
ENSMUST00000033876.7
Gpr124

G protein-coupled receptor 124

chr7_-_47132698 1.927 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr15_-_75566608 1.910 ENSMUST00000163116.1
ENSMUST00000023241.5
Ly6h

lymphocyte antigen 6 complex, locus H

chr4_+_129985098 1.904 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2

brain-specific angiogenesis inhibitor 2

chrX_-_160994665 1.900 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr4_-_151861667 1.874 ENSMUST00000169423.2
Camta1
calmodulin binding transcription activator 1
chr17_+_68837062 1.839 ENSMUST00000178545.1
Tmem200c
transmembrane protein 200C
chr9_-_24503127 1.836 ENSMUST00000142064.1
ENSMUST00000170356.1
Dpy19l1

dpy-19-like 1 (C. elegans)

chr11_-_94474088 1.830 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr17_-_29237759 1.808 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr2_-_94406647 1.807 ENSMUST00000111237.2
ENSMUST00000094801.4
ENSMUST00000111238.1
Ttc17


tetratricopeptide repeat domain 17


chr3_+_98382538 1.807 ENSMUST00000178372.1
Zfp697
zinc finger protein 697
chr2_-_166155624 1.790 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr5_-_36530610 1.771 ENSMUST00000171385.1
Tbc1d14
TBC1 domain family, member 14
chr19_+_10041548 1.769 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr2_+_32395896 1.766 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr11_+_103171081 1.754 ENSMUST00000042286.5
Fmnl1
formin-like 1
chr16_-_18629864 1.694 ENSMUST00000096987.5
Sept5
septin 5
chr4_+_42949814 1.675 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr6_-_8778439 1.670 ENSMUST00000115520.1
ENSMUST00000038403.5
ENSMUST00000115518.1
Ica1


islet cell autoantigen 1


chr2_-_180273488 1.668 ENSMUST00000108891.1
Cables2
CDK5 and Abl enzyme substrate 2
chr12_-_72408934 1.664 ENSMUST00000078505.7
Rtn1
reticulon 1
chr10_-_118868903 1.663 ENSMUST00000004281.8
Dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr13_+_54949388 1.646 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr15_+_27466647 1.634 ENSMUST00000022875.6
Ank
progressive ankylosis
chr6_-_8778106 1.614 ENSMUST00000151758.1
ENSMUST00000115519.1
ENSMUST00000153390.1
Ica1


islet cell autoantigen 1


chr11_-_102447647 1.609 ENSMUST00000049057.4
Fam171a2
family with sequence similarity 171, member A2
chr3_+_98382438 1.595 ENSMUST00000056096.8
Zfp697
zinc finger protein 697
chr11_-_98018308 1.587 ENSMUST00000107561.2
Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr4_+_42950369 1.580 ENSMUST00000084662.5
Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr7_-_74013676 1.572 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr10_-_78352469 1.566 ENSMUST00000138035.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr12_+_81859964 1.563 ENSMUST00000021567.5
Pcnx
pecanex homolog (Drosophila)
chr7_+_99381495 1.528 ENSMUST00000037528.8
Gdpd5
glycerophosphodiester phosphodiesterase domain containing 5
chr5_-_136244865 1.491 ENSMUST00000005188.9
Sh2b2
SH2B adaptor protein 2
chr8_-_84800344 1.483 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr2_-_27475600 1.482 ENSMUST00000147736.1
Brd3
bromodomain containing 3
chr14_+_121035538 1.477 ENSMUST00000026635.7
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr6_-_120493807 1.470 ENSMUST00000178687.1
Cecr6
cat eye syndrome chromosome region, candidate 6
chr15_+_78913916 1.464 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr5_-_115272883 1.431 ENSMUST00000040555.8
ENSMUST00000112096.2
ENSMUST00000112097.1
Rnf10


ring finger protein 10


chr14_-_24245913 1.428 ENSMUST00000073687.6
ENSMUST00000090398.4
Dlg5

discs, large homolog 5 (Drosophila)

chr5_+_146384947 1.414 ENSMUST00000110600.1
ENSMUST00000016143.7
Wasf3

WAS protein family, member 3

chr4_+_149586555 1.406 ENSMUST00000039144.6
Clstn1
calsyntenin 1
chr2_-_152398046 1.399 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr2_-_166155272 1.395 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr15_-_85581809 1.380 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr7_+_67952817 1.363 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chr7_-_65156416 1.339 ENSMUST00000148459.1
ENSMUST00000119118.1
Fam189a1

family with sequence similarity 189, member A1

chr1_+_191718389 1.338 ENSMUST00000110856.1
ENSMUST00000130876.1
Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr4_+_106911517 1.335 ENSMUST00000072753.6
ENSMUST00000097934.3
Ssbp3

single-stranded DNA binding protein 3

chr9_-_95750335 1.326 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr12_-_99393010 1.306 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr1_+_135146782 1.304 ENSMUST00000027684.4
Arl8a
ADP-ribosylation factor-like 8A
chr4_+_43957678 1.302 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr14_+_57524734 1.298 ENSMUST00000089494.4
Il17d
interleukin 17D
chr5_+_137288273 1.277 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr6_+_30401866 1.276 ENSMUST00000068240.6
ENSMUST00000068259.6
Klhdc10

kelch domain containing 10

chr17_+_8801742 1.250 ENSMUST00000089085.2
Pde10a
phosphodiesterase 10A
chr2_+_28192971 1.242 ENSMUST00000113920.1
Olfm1
olfactomedin 1
chr2_+_157914618 1.233 ENSMUST00000109523.1
Vstm2l
V-set and transmembrane domain containing 2-like
chr9_+_106368594 1.223 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr10_-_78352212 1.218 ENSMUST00000146899.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr3_-_117868821 1.198 ENSMUST00000167877.1
ENSMUST00000169812.1
Snx7

sorting nexin 7

chr7_-_19665005 1.180 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr19_-_47464406 1.177 ENSMUST00000111800.2
ENSMUST00000081619.2
Sh3pxd2a

SH3 and PX domains 2A

chr19_+_6241668 1.172 ENSMUST00000045351.6
Atg2a
autophagy related 2A
chr4_+_43957401 1.166 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr2_+_156613664 1.151 ENSMUST00000169464.2
ENSMUST00000109567.3
Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr7_-_130266191 1.145 ENSMUST00000122054.1
Fgfr2
fibroblast growth factor receptor 2
chr11_+_121259983 1.133 ENSMUST00000106113.1
Foxk2
forkhead box K2
chr2_+_30982350 1.122 ENSMUST00000061544.4
ENSMUST00000138161.1
ENSMUST00000142232.1
Usp20


ubiquitin specific peptidase 20


chr8_+_95081187 1.115 ENSMUST00000034239.7
Katnb1
katanin p80 (WD40-containing) subunit B 1
chr9_+_58582240 1.095 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr9_+_58582397 1.085 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr7_-_45366714 1.073 ENSMUST00000107779.1
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr14_+_25607797 1.068 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr8_+_85036906 1.033 ENSMUST00000093360.4
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr3_-_117868930 1.031 ENSMUST00000029639.5
Snx7
sorting nexin 7
chr17_-_66519666 1.029 ENSMUST00000167962.1
ENSMUST00000070538.4
Rab12

RAB12, member RAS oncogene family

chr17_+_24470393 1.014 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr8_+_83900096 1.012 ENSMUST00000141158.1
Lphn1
latrophilin 1
chrX_+_119927196 1.003 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5

poly(A) binding protein, cytoplasmic 5

chr3_-_89773221 1.001 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr11_+_69901816 0.984 ENSMUST00000177138.1
ENSMUST00000108617.3
ENSMUST00000177476.1
ENSMUST00000061837.4
Neurl4



neuralized homolog 4 (Drosophila)



chr2_+_28193093 0.982 ENSMUST00000100244.3
Olfm1
olfactomedin 1
chr13_-_117025505 0.972 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr5_-_122988533 0.966 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr10_+_127380799 0.965 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr10_-_78352323 0.964 ENSMUST00000001240.5
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr2_-_35979624 0.964 ENSMUST00000028248.4
ENSMUST00000112976.2
Ttll11

tubulin tyrosine ligase-like family, member 11

chr11_+_22990519 0.961 ENSMUST00000173867.1
ENSMUST00000020562.4
Cct4

chaperonin containing Tcp1, subunit 4 (delta)

chr1_-_36558214 0.957 ENSMUST00000154493.1
Sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr6_+_125145235 0.947 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr8_+_27085835 0.943 ENSMUST00000165366.2
Gpr124
G protein-coupled receptor 124
chr3_+_89773562 0.936 ENSMUST00000038356.8
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr8_+_85037151 0.932 ENSMUST00000166592.1
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr3_+_95658771 0.929 ENSMUST00000178686.1
Mcl1
myeloid cell leukemia sequence 1
chr14_+_99298652 0.928 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr17_+_34031787 0.928 ENSMUST00000044858.8
Rxrb
retinoid X receptor beta
chr11_+_94990996 0.927 ENSMUST00000038696.5
Ppp1r9b
protein phosphatase 1, regulatory subunit 9B
chr5_+_123394782 0.923 ENSMUST00000111596.1
ENSMUST00000068237.5
Mlxip

MLX interacting protein

chr17_+_46161111 0.916 ENSMUST00000166563.1
Gtpbp2
GTP binding protein 2
chr19_-_5688908 0.902 ENSMUST00000113615.2
Pcnxl3
pecanex-like 3 (Drosophila)
chr7_+_3332918 0.892 ENSMUST00000092891.4
Cacng7
calcium channel, voltage-dependent, gamma subunit 7
chr9_+_108692116 0.878 ENSMUST00000035220.6
Prkar2a
protein kinase, cAMP dependent regulatory, type II alpha
chr1_+_75479529 0.873 ENSMUST00000113575.2
ENSMUST00000148980.1
ENSMUST00000050899.6
Tmem198


transmembrane protein 198


chr13_+_54503779 0.863 ENSMUST00000121401.1
ENSMUST00000118072.1
ENSMUST00000159721.1
Simc1


SUMO-interacting motifs containing 1


chr19_-_6118491 0.861 ENSMUST00000113533.1
Sac3d1
SAC3 domain containing 1
chr4_+_149586432 0.853 ENSMUST00000105691.1
Clstn1
calsyntenin 1
chr2_-_132145057 0.843 ENSMUST00000028815.8
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr16_-_37539781 0.840 ENSMUST00000023525.8
Gtf2e1
general transcription factor II E, polypeptide 1 (alpha subunit)
chr8_+_111536793 0.833 ENSMUST00000095176.5
Znrf1
zinc and ring finger 1
chr19_+_9982694 0.828 ENSMUST00000025563.6
Fth1
ferritin heavy chain 1
chr7_-_27674516 0.826 ENSMUST00000036453.7
ENSMUST00000108341.1
Map3k10

mitogen-activated protein kinase kinase kinase 10

chr7_+_100706623 0.825 ENSMUST00000107042.1
Fam168a
family with sequence similarity 168, member A
chr6_-_124756478 0.818 ENSMUST00000088357.5
Atn1
atrophin 1
chr15_+_87625214 0.818 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr12_+_3806513 0.815 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr4_-_108780782 0.813 ENSMUST00000106657.1
Zfyve9
zinc finger, FYVE domain containing 9
chr11_+_32642706 0.808 ENSMUST00000109366.1
Fbxw11
F-box and WD-40 domain protein 11
chr11_-_97574040 0.806 ENSMUST00000107593.1
Srcin1
SRC kinase signaling inhibitor 1
chr4_+_129984833 0.801 ENSMUST00000120204.1
Bai2
brain-specific angiogenesis inhibitor 2
chr9_-_106789130 0.799 ENSMUST00000046502.5
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr13_-_32338565 0.784 ENSMUST00000041859.7
Gmds
GDP-mannose 4, 6-dehydratase
chr4_-_151861698 0.783 ENSMUST00000049790.7
Camta1
calmodulin binding transcription activator 1
chr7_-_120982260 0.783 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr11_+_32642826 0.776 ENSMUST00000093205.6
ENSMUST00000076383.7
Fbxw11

F-box and WD-40 domain protein 11

chr8_+_111537000 0.775 ENSMUST00000173506.1
Znrf1
zinc and ring finger 1
chr19_-_4306214 0.766 ENSMUST00000171123.1
ENSMUST00000088737.4
Adrbk1

adrenergic receptor kinase, beta 1

chr14_+_20707548 0.746 ENSMUST00000022358.7
Zswim8
zinc finger SWIM-type containing 8
chr9_+_61373608 0.746 ENSMUST00000161689.1
Tle3
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr11_+_69765899 0.744 ENSMUST00000108640.1
ENSMUST00000108639.1
Zbtb4

zinc finger and BTB domain containing 4

chr2_-_152831665 0.737 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr3_-_90509450 0.729 ENSMUST00000107343.1
ENSMUST00000001043.7
ENSMUST00000107344.1
ENSMUST00000076639.4
ENSMUST00000107346.1
ENSMUST00000146740.1
ENSMUST00000107342.1
ENSMUST00000049937.6
Chtop







chromatin target of PRMT1







chr11_+_69765970 0.728 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr9_+_61373482 0.724 ENSMUST00000160541.1
ENSMUST00000161207.1
ENSMUST00000159630.1
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr16_+_20517000 0.723 ENSMUST00000171572.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr4_-_108780503 0.713 ENSMUST00000106658.1
Zfyve9
zinc finger, FYVE domain containing 9
chr1_-_177258182 0.709 ENSMUST00000111159.1
Akt3
thymoma viral proto-oncogene 3
chr9_-_44320229 0.696 ENSMUST00000065080.8
C2cd2l
C2 calcium-dependent domain containing 2-like
chr11_-_97573929 0.693 ENSMUST00000126287.1
ENSMUST00000107590.1
Srcin1

SRC kinase signaling inhibitor 1

chr4_-_148287927 0.692 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr17_-_24073479 0.692 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr2_+_71873224 0.690 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr15_+_74516196 0.689 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr11_-_96829959 0.683 ENSMUST00000081775.5
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr10_-_78352053 0.673 ENSMUST00000105388.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr12_-_112673944 0.667 ENSMUST00000130342.1
Akt1
thymoma viral proto-oncogene 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.5 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
1.6 4.7 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
1.5 13.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.4 4.3 GO:0060596 mammary placode formation(GO:0060596)
1.4 5.6 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
1.0 2.9 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.9 4.7 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.9 4.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.8 3.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.8 2.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.8 7.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.7 2.0 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.7 2.6 GO:0021586 pons maturation(GO:0021586)
0.6 1.8 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.6 1.7 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.5 1.4 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) trachea cartilage morphogenesis(GO:0060535)
0.4 1.3 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.4 2.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.4 2.2 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.4 2.5 GO:0016266 O-glycan processing(GO:0016266)
0.4 0.8 GO:0009405 pathogenesis(GO:0009405)
0.4 2.4 GO:0051013 microtubule severing(GO:0051013)
0.4 2.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.4 1.9 GO:2001025 positive regulation of response to drug(GO:2001025)
0.4 1.5 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.4 6.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.4 1.1 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.3 1.4 GO:0044849 estrous cycle(GO:0044849) cholangiocyte apoptotic process(GO:1902488) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.3 1.0 GO:0019401 alditol biosynthetic process(GO:0019401)
0.3 4.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.3 1.3 GO:0046898 response to cycloheximide(GO:0046898)
0.3 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003) cellular response to isoquinoline alkaloid(GO:0071317) regulation of opioid receptor signaling pathway(GO:2000474)
0.3 4.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.3 5.4 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.3 1.8 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.3 1.4 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.3 1.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.3 0.8 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 0.8 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.3 1.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.3 2.8 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 3.5 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.2 1.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 0.7 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 1.2 GO:0072675 osteoclast fusion(GO:0072675)
0.2 4.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.9 GO:0070459 prolactin secretion(GO:0070459)
0.2 0.9 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 2.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 1.3 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.6 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.2 1.3 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.2 1.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 2.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 0.6 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 1.8 GO:0051014 actin filament severing(GO:0051014)
0.2 2.5 GO:0033574 response to testosterone(GO:0033574)
0.2 1.0 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 1.0 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 1.5 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.2 0.9 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 1.8 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.2 2.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 1.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.7 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.2 1.3 GO:0046541 saliva secretion(GO:0046541)
0.2 4.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 0.6 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 0.6 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 1.1 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 3.6 GO:0016578 histone deubiquitination(GO:0016578)
0.1 3.3 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 3.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 1.8 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 2.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 1.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 1.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.3 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.3 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.5 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 1.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 0.8 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 0.3 GO:1905072 detection of oxygen(GO:0003032) establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009) cardiac jelly development(GO:1905072)
0.1 1.8 GO:0044804 nucleophagy(GO:0044804)
0.1 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.1 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 2.0 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.5 GO:0050862 behavioral response to ethanol(GO:0048149) positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 1.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 1.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.5 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.1 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 2.3 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 0.8 GO:0097286 iron ion import(GO:0097286)
0.1 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 2.4 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.4 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.5 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.2 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 1.0 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 3.2 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 1.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.1 GO:0045453 bone resorption(GO:0045453)
0.0 1.2 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 2.2 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 1.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 3.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 5.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.7 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 2.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.0 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.5 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.4 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 1.8 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 3.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:2000672 regulation of motor neuron apoptotic process(GO:2000671) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 2.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.2 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.0 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.9 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 1.5 GO:0030041 actin filament polymerization(GO:0030041)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 13.4 GO:0045298 tubulin complex(GO:0045298)
1.1 4.4 GO:1990032 parallel fiber(GO:1990032)
1.0 2.9 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.9 2.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 2.8 GO:0030314 junctional membrane complex(GO:0030314)
0.4 4.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.4 2.2 GO:0045179 apical cortex(GO:0045179)
0.3 1.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 2.3 GO:0005883 neurofilament(GO:0005883)
0.2 6.0 GO:0071565 nBAF complex(GO:0071565)
0.2 0.7 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 4.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 0.6 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 2.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 4.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.3 GO:0000124 SAGA complex(GO:0000124)
0.2 3.5 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.9 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 5.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.3 GO:0000125 PCAF complex(GO:0000125)
0.1 3.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 6.4 GO:0031201 SNARE complex(GO:0031201)
0.1 10.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.7 GO:0031105 septin complex(GO:0031105)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.5 GO:0070938 contractile ring(GO:0070938)
0.1 0.7 GO:0097413 Lewy body(GO:0097413)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.9 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.2 GO:0098830 presynaptic endosome(GO:0098830)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 3.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 3.3 GO:0005776 autophagosome(GO:0005776)
0.1 0.8 GO:0044754 autolysosome(GO:0044754)
0.1 1.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 3.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 4.6 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0051233 spindle midzone(GO:0051233)
0.0 1.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 6.3 GO:0030027 lamellipodium(GO:0030027)
0.0 10.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 6.8 GO:0005769 early endosome(GO:0005769)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.3 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 5.1 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 3.6 GO:0009986 cell surface(GO:0009986)
0.0 0.5 GO:0031256 leading edge membrane(GO:0031256) ruffle membrane(GO:0032587)
0.0 2.9 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0005819 spindle(GO:0005819)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0098793 presynapse(GO:0098793)
0.0 0.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.7 GO:0097060 synaptic membrane(GO:0097060)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 13.4 GO:0099609 microtubule lateral binding(GO:0099609)
1.6 4.7 GO:0051379 epinephrine binding(GO:0051379)
0.8 5.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.7 4.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.7 7.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.7 2.0 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6 3.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 4.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.5 1.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.4 1.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.4 3.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.4 2.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.4 1.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.4 2.8 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.4 1.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.4 6.0 GO:0045499 chemorepellent activity(GO:0045499)
0.3 1.4 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.3 1.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.3 1.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 4.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 2.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 0.8 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 1.6 GO:0005042 netrin receptor activity(GO:0005042)
0.3 4.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 4.7 GO:0050811 GABA receptor binding(GO:0050811)
0.3 1.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 2.1 GO:0043559 insulin binding(GO:0043559)
0.3 4.6 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 2.2 GO:0051434 BH3 domain binding(GO:0051434)
0.2 4.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 0.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 1.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 0.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 1.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.5 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.2 2.3 GO:0015643 toxic substance binding(GO:0015643)
0.2 1.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 6.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 3.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 2.9 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.1 2.2 GO:0004697 protein kinase C activity(GO:0004697)
0.1 5.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.9 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 1.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 6.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 3.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.3 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 2.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.6 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 3.0 GO:0019003 GDP binding(GO:0019003)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 4.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 3.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 3.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 3.2 GO:0005496 steroid binding(GO:0005496)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.9 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 4.9 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 6.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 3.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 6.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.3 4.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 6.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.2 1.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 4.9 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.9 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 1.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 4.3 PID_LKB1_PATHWAY LKB1 signaling events
0.1 2.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.4 PID_IGF1_PATHWAY IGF1 pathway
0.1 1.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.5 ST_GAQ_PATHWAY G alpha q Pathway
0.0 2.0 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 1.2 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 4.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.3 PID_MYC_PATHWAY C-MYC pathway
0.0 0.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.6 13.4 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 4.7 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.4 2.8 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.4 4.3 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.3 1.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.2 10.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.7 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 2.9 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 4.4 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 4.4 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.3 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 0.7 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.8 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 0.5 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.5 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.7 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.1 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.9 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 2.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 1.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK