ISMARA results: Mga

Motif ID: Mga

Z-value: 0.513

Transcription factors associated with Mga:

Gene Symbol	Entrez ID	Gene Name
Mga	ENSMUSG00000033943.9	Mga

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Mga	mm10_v2_chr2_+_119897212_119897305	0.39	3.5e-03	Click!

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Showing 1 to 20 of 78 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_-_43869993	1.966	ENSMUST00000067469.4	Tmem74	transmembrane protein 74
chrX_+_35888808	1.679	ENSMUST00000033419.6	Dock11	dedicator of cytokinesis 11
chr6_-_41636389	1.606	ENSMUST00000031902.5	Trpv6	transient receptor potential cation channel, subfamily V, member 6
chr5_-_138619702	1.523	ENSMUST00000063262.4	Zfp68	zinc finger protein 68
chr5_-_138619751	1.317	ENSMUST00000085852.4 ENSMUST00000110905.2	Zfp68	zinc finger protein 68
chr4_+_95967322	1.250	ENSMUST00000107083.1	Hook1	hook homolog 1 (Drosophila)
chr11_+_49203465	1.241	ENSMUST00000150284.1 ENSMUST00000109197.1 ENSMUST00000151228.1	Zfp62	zinc finger protein 62
chr8_+_12984246	1.206	ENSMUST00000110873.3 ENSMUST00000173006.1 ENSMUST00000145067.1	Mcf2l	mcf.2 transforming sequence-like
chr14_+_64652524	1.059	ENSMUST00000100473.4	Kif13b	kinesin family member 13B
chr11_+_49203285	1.052	ENSMUST00000109198.1 ENSMUST00000137061.2	Zfp62	zinc finger protein 62
chr5_-_138619653	1.048	ENSMUST00000129832.1	Zfp68	zinc finger protein 68
chr3_+_76075583	0.839	ENSMUST00000160261.1	Fstl5	follistatin-like 5
chr9_+_57940104	0.803	ENSMUST00000043059.7	Sema7a	sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr6_-_149188648	0.798	ENSMUST00000095319.3 ENSMUST00000141346.1 ENSMUST00000111535.1	Amn1	antagonist of mitotic exit network 1
chr8_+_3393018	0.788	ENSMUST00000004684.6 ENSMUST00000145394.1	Arhgef18	rho/rac guanine nucleotide exchange factor (GEF) 18
chrX_+_163909132	0.757	ENSMUST00000033734.7 ENSMUST00000112294.2	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit
chr13_+_29016267	0.745	ENSMUST00000140415.1	A330102I10Rik	RIKEN cDNA A330102I10 gene
chr3_+_124321031	0.735	ENSMUST00000058994.4	Tram1l1	translocation associated membrane protein 1-like 1
chr9_-_85749308	0.727	ENSMUST00000039213.8	Ibtk	inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr10_+_81575306	0.717	ENSMUST00000146916.1	Tle2	transducin-like enhancer of split 2, homolog of Drosophila E(spl)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 28 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.7	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.2	1.6	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0	1.2	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	1.2	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	1.2	GO:0008333	endosome to lysosome transport(GO:0008333)
0.2	0.9	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	0.9	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.8	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.8	GO:0060612	adipose tissue development(GO:0060612)
0.1	0.6	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	0.6	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.6	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.2	0.5	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0	0.5	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.5	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.5	GO:0060325	face morphogenesis(GO:0060325)
0.1	0.4	GO:0002030	inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.1	0.4	GO:0002946	tRNA C5-cytosine methylation(GO:0002946)
0.1	0.4	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.4	GO:0007602	phototransduction(GO:0007602)

Gene overrepresentation in cellular_component category:

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Showing 1 to 12 of 12 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.7	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1	1.4	GO:0070545	PeBoW complex(GO:0070545)
0.2	1.2	GO:0070695	FHF complex(GO:0070695)
0.0	1.2	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	1.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.9	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.6	GO:0031209	SCAR complex(GO:0031209)
0.0	0.6	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.6	GO:0097440	apical dendrite(GO:0097440)
0.0	0.5	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0045180	basal cortex(GO:0045180)
0.0	0.3	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)

Gene overrepresentation in molecular_function category:

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Showing 1 to 19 of 19 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.5	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	1.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	1.2	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	1.1	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	0.9	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	0.9	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	0.8	GO:0038191	neuropilin binding(GO:0038191)
0.2	0.7	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.6	GO:0045182	translation regulator activity(GO:0045182)
0.1	0.5	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.5	GO:0001056	RNA polymerase III activity(GO:0001056)
0.1	0.4	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0	0.4	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.1	0.3	GO:0017084	glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)

Gene overrepresentation in C2:CP category:

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Showing 1 to 9 of 9 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID_CDC42_REG_PATHWAY	Regulation of CDC42 activity
0.0	1.6	PID_PTP1B_PATHWAY	Signaling events mediated by PTP1B
0.0	1.3	PID_BETA_CATENIN_NUC_PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.1	PID_ARF6_PATHWAY	Arf6 signaling events
0.0	0.8	PID_RHOA_REG_PATHWAY	Regulation of RhoA activity
0.0	0.7	PID_BCR_5PATHWAY	BCR signaling pathway
0.0	0.6	PID_RAC1_PATHWAY	RAC1 signaling pathway
0.0	0.4	PID_RHODOPSIN_PATHWAY	Visual signal transduction: Rods
0.0	0.1	SA_MMP_CYTOKINE_CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 9 of 9 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.3	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	0.8	REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.8	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.8	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.5	REACTOME_RNA_POL_III_CHAIN_ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	0.4	REACTOME_OLFACTORY_SIGNALING_PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.3	REACTOME_PYRIMIDINE_CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)