Motif ID: Myb
Z-value: 2.104
Transcription factors associated with Myb:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Myb | ENSMUSG00000019982.8 | Myb |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Myb | mm10_v2_chr10_-_21160925_21160984 | 0.87 | 9.3e-18 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.0 | 27.1 | GO:0072382 | minus-end-directed vesicle transport along microtubule(GO:0072382) |
| 7.0 | 20.9 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 5.5 | 32.9 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 4.6 | 13.8 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 4.5 | 80.7 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 4.0 | 27.9 | GO:0000279 | M phase(GO:0000279) |
| 4.0 | 23.8 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 3.2 | 16.0 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 2.9 | 14.4 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 2.1 | 33.4 | GO:0070986 | left/right axis specification(GO:0070986) |
| 2.1 | 35.0 | GO:0030953 | astral microtubule organization(GO:0030953) |
| 1.9 | 3.8 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
| 1.9 | 13.1 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 1.8 | 7.2 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 1.7 | 11.8 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 1.6 | 16.3 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 1.6 | 4.9 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 1.6 | 12.4 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 1.4 | 19.5 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 1.3 | 8.0 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
| 1.3 | 9.1 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
| 1.2 | 7.4 | GO:1901911 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 1.1 | 9.8 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 1.1 | 5.3 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
| 1.0 | 4.2 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 1.0 | 16.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.9 | 7.5 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.9 | 11.7 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.9 | 4.4 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.9 | 2.6 | GO:0014028 | notochord formation(GO:0014028) |
| 0.8 | 5.0 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.8 | 14.6 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.8 | 7.0 | GO:0071397 | cellular response to cholesterol(GO:0071397) |
| 0.7 | 2.2 | GO:0019659 | fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 0.7 | 2.2 | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
| 0.7 | 8.9 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.7 | 5.0 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.7 | 4.3 | GO:0006528 | asparagine metabolic process(GO:0006528) |
| 0.7 | 4.3 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.7 | 2.1 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
| 0.7 | 2.8 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.7 | 3.4 | GO:0044340 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340) |
| 0.6 | 2.5 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.6 | 2.5 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
| 0.6 | 12.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.6 | 3.4 | GO:2001170 | negative regulation of ATP biosynthetic process(GO:2001170) |
| 0.5 | 17.0 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.5 | 3.3 | GO:1902965 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 0.5 | 2.7 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.5 | 1.6 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.5 | 2.6 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038) |
| 0.5 | 1.6 | GO:1901420 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) negative regulation of response to alcohol(GO:1901420) positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.5 | 2.5 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
| 0.5 | 5.0 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.5 | 14.8 | GO:0007099 | centriole replication(GO:0007099) |
| 0.5 | 1.4 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.4 | 1.8 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
| 0.4 | 3.5 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.4 | 1.7 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.4 | 1.3 | GO:0090202 | transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
| 0.4 | 1.6 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 0.4 | 12.7 | GO:0034508 | centromere complex assembly(GO:0034508) |
| 0.4 | 2.8 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.4 | 3.9 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.4 | 4.2 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.4 | 1.1 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.3 | 2.8 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.3 | 1.7 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.3 | 1.6 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.3 | 2.3 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.3 | 4.9 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.3 | 2.1 | GO:0030242 | pexophagy(GO:0030242) |
| 0.3 | 6.3 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.3 | 0.9 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
| 0.3 | 1.4 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.3 | 1.1 | GO:0045358 | negative regulation of interferon-beta biosynthetic process(GO:0045358) |
| 0.3 | 1.8 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
| 0.3 | 8.9 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.3 | 1.3 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.2 | 2.5 | GO:0046051 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 0.2 | 4.2 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.2 | 2.5 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.2 | 1.6 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.2 | 4.9 | GO:2001273 | regulation of glucose import in response to insulin stimulus(GO:2001273) |
| 0.2 | 0.7 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
| 0.2 | 3.7 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.2 | 4.0 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.2 | 9.6 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.2 | 1.6 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.2 | 1.6 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.2 | 18.8 | GO:0007093 | mitotic cell cycle checkpoint(GO:0007093) |
| 0.2 | 1.8 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.2 | 1.1 | GO:0009169 | purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) |
| 0.2 | 2.5 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.2 | 2.6 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.2 | 0.5 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
| 0.1 | 1.3 | GO:0002155 | regulation of thyroid hormone mediated signaling pathway(GO:0002155) |
| 0.1 | 10.3 | GO:0007127 | meiosis I(GO:0007127) |
| 0.1 | 0.4 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 0.6 | GO:0061739 | protein lipidation involved in autophagosome assembly(GO:0061739) |
| 0.1 | 1.3 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.1 | 5.0 | GO:0048255 | mRNA stabilization(GO:0048255) |
| 0.1 | 0.9 | GO:0043634 | polyadenylation-dependent ncRNA catabolic process(GO:0043634) |
| 0.1 | 6.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 2.1 | GO:0000070 | mitotic sister chromatid segregation(GO:0000070) |
| 0.1 | 0.6 | GO:0033762 | response to glucagon(GO:0033762) |
| 0.1 | 0.4 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
| 0.1 | 0.4 | GO:0045091 | regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) |
| 0.1 | 12.3 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.1 | 1.0 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.1 | 3.0 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
| 0.1 | 2.5 | GO:2000780 | negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780) |
| 0.1 | 0.8 | GO:1902231 | hematopoietic stem cell migration(GO:0035701) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.1 | 0.2 | GO:0033600 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) |
| 0.1 | 1.0 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.1 | 0.7 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.1 | 0.4 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.1 | 0.8 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 1.0 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.1 | 0.5 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.1 | 2.0 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.1 | 1.0 | GO:0044380 | protein localization to cytoskeleton(GO:0044380) |
| 0.1 | 0.7 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.1 | 0.9 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.1 | 0.6 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 0.7 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.1 | 1.8 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.1 | 4.1 | GO:0000271 | polysaccharide biosynthetic process(GO:0000271) |
| 0.1 | 1.2 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.1 | 2.5 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
| 0.1 | 1.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 7.1 | GO:0000082 | G1/S transition of mitotic cell cycle(GO:0000082) |
| 0.1 | 0.3 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
| 0.1 | 10.0 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 0.1 | 1.1 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.1 | 2.3 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.1 | 1.1 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.1 | 4.5 | GO:0008584 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.1 | 1.6 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.8 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 9.0 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 0.3 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.5 | GO:0030728 | ovulation(GO:0030728) |
| 0.0 | 21.5 | GO:0051301 | cell division(GO:0051301) |
| 0.0 | 0.3 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.0 | 2.9 | GO:0070373 | negative regulation of ERK1 and ERK2 cascade(GO:0070373) |
| 0.0 | 2.2 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
| 0.0 | 0.8 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.6 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 0.5 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
| 0.0 | 1.1 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 0.9 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.0 | 1.2 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.0 | 2.4 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.0 | 1.4 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.2 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.3 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.3 | GO:0043631 | mRNA polyadenylation(GO:0006378) mRNA 3'-end processing(GO:0031124) RNA polyadenylation(GO:0043631) |
| 0.0 | 2.6 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
| 0.0 | 1.9 | GO:0030218 | erythrocyte differentiation(GO:0030218) |
| 0.0 | 2.7 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 0.9 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 1.4 | GO:0048663 | neuron fate commitment(GO:0048663) |
| 0.0 | 1.3 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
| 0.0 | 1.1 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.0 | 0.8 | GO:0045860 | positive regulation of protein kinase activity(GO:0045860) |
| 0.0 | 0.2 | GO:0042119 | neutrophil activation(GO:0042119) |
| 0.0 | 0.5 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.7 | 20.0 | GO:1990423 | RZZ complex(GO:1990423) |
| 6.5 | 19.5 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
| 5.2 | 20.9 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
| 4.6 | 13.8 | GO:0042585 | germinal vesicle(GO:0042585) |
| 3.0 | 32.6 | GO:0005642 | annulate lamellae(GO:0005642) |
| 1.9 | 13.4 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 1.9 | 70.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 1.6 | 4.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 1.5 | 27.1 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 1.5 | 10.4 | GO:0001940 | male pronucleus(GO:0001940) |
| 1.4 | 2.8 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 1.4 | 4.2 | GO:1990047 | spindle matrix(GO:1990047) |
| 1.1 | 27.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 1.1 | 4.3 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
| 1.1 | 7.5 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 1.0 | 6.0 | GO:0035976 | AP1 complex(GO:0035976) |
| 1.0 | 5.9 | GO:0098536 | deuterosome(GO:0098536) |
| 0.9 | 6.3 | GO:0001740 | Barr body(GO:0001740) |
| 0.9 | 4.3 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
| 0.8 | 5.9 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.8 | 2.5 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 0.8 | 5.3 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.8 | 2.3 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
| 0.6 | 1.9 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.6 | 15.6 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.5 | 1.6 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.5 | 10.7 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.5 | 33.2 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.5 | 12.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.5 | 1.4 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.4 | 2.2 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.4 | 24.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.4 | 3.8 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.4 | 1.3 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.4 | 4.2 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.4 | 5.5 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.4 | 20.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.3 | 34.7 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.3 | 1.6 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.3 | 0.9 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.3 | 24.7 | GO:0005814 | centriole(GO:0005814) |
| 0.3 | 32.4 | GO:0000776 | kinetochore(GO:0000776) |
| 0.3 | 1.8 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.2 | 16.9 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.2 | 2.1 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.2 | 1.0 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.2 | 4.8 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.2 | 3.4 | GO:0005605 | basal lamina(GO:0005605) |
| 0.2 | 1.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 10.4 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.2 | 1.0 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.2 | 2.2 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.2 | 2.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.2 | 2.5 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 1.8 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.1 | 5.0 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 49.6 | GO:0005813 | centrosome(GO:0005813) |
| 0.1 | 0.4 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.1 | 0.9 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 19.8 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 2.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 9.1 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.1 | 1.9 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.1 | 3.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 2.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 2.6 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 3.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 7.0 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 1.0 | GO:0005671 | SAGA complex(GO:0000124) Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 6.2 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 0.6 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 3.3 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.5 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 4.3 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 1.0 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 2.7 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.6 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 1.7 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 7.8 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.9 | GO:1990204 | oxidoreductase complex(GO:1990204) |
| 0.0 | 4.1 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 4.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.5 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 1.1 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.9 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 4.8 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 2.5 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 8.4 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 0.7 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.3 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.6 | 27.9 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 2.8 | 11.2 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 2.8 | 13.8 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 2.7 | 10.7 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 2.5 | 7.5 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
| 2.5 | 9.9 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 2.1 | 29.5 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 2.1 | 32.9 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 1.8 | 10.9 | GO:0008494 | translation activator activity(GO:0008494) |
| 1.6 | 19.5 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 1.2 | 7.4 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
| 1.0 | 4.2 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 1.0 | 13.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 1.0 | 16.3 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.7 | 10.4 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.6 | 14.2 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.6 | 4.3 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.6 | 2.2 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.6 | 4.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.5 | 1.6 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.5 | 1.9 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.4 | 2.6 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.4 | 12.6 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.4 | 7.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.4 | 4.3 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.4 | 4.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.4 | 0.4 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
| 0.3 | 24.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.3 | 4.8 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.3 | 3.4 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.3 | 9.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.3 | 15.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.3 | 2.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.3 | 5.0 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.3 | 11.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.3 | 2.7 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.3 | 5.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.3 | 1.8 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.2 | 1.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.2 | 3.0 | GO:0031386 | protein tag(GO:0031386) |
| 0.2 | 1.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 1.5 | GO:0032564 | dATP binding(GO:0032564) |
| 0.2 | 2.5 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.2 | 1.3 | GO:0043141 | TFIID-class transcription factor binding(GO:0001094) ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.2 | 1.2 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.2 | 2.5 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.2 | 1.6 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.2 | 8.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.2 | 2.4 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.2 | 3.1 | GO:0051861 | glycolipid binding(GO:0051861) |
| 0.2 | 1.8 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.2 | 0.7 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
| 0.2 | 1.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.2 | 6.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.2 | 11.8 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 0.2 | 4.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 1.5 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.1 | 3.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 6.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 5.0 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 0.7 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 3.9 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 5.5 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 0.9 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.1 | 0.8 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 1.4 | GO:0048038 | quinone binding(GO:0048038) |
| 0.1 | 30.8 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 2.5 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.1 | 2.2 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.1 | 0.4 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.1 | 0.9 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 1.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 0.5 | GO:0019841 | retinol binding(GO:0019841) |
| 0.1 | 6.9 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.1 | 2.3 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.1 | 11.7 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 0.8 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 2.8 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.1 | 2.6 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.1 | 1.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 0.2 | GO:0019863 | IgE binding(GO:0019863) |
| 0.1 | 3.2 | GO:0003774 | motor activity(GO:0003774) |
| 0.1 | 2.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 3.7 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 2.7 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 2.5 | GO:0004386 | helicase activity(GO:0004386) |
| 0.1 | 26.7 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.0 | 0.6 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.2 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.0 | 0.7 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.0 | 1.0 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.0 | 1.9 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.6 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 1.4 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.5 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 1.0 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.8 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 2.1 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 2.8 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 0.4 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 1.8 | GO:0008173 | RNA methyltransferase activity(GO:0008173) |
| 0.0 | 0.6 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 1.5 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.0 | 0.5 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.8 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.3 | GO:0015149 | hexose transmembrane transporter activity(GO:0015149) |
| 0.0 | 10.7 | GO:0019904 | protein domain specific binding(GO:0019904) |
| 0.0 | 6.6 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 0.8 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 1.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 89.9 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 1.0 | 60.5 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.8 | 19.5 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.5 | 5.0 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.4 | 12.6 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.4 | 11.6 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.3 | 11.7 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.2 | 4.9 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
| 0.2 | 18.0 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.2 | 12.0 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
| 0.2 | 6.4 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.2 | 2.6 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.2 | 4.6 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.2 | 2.1 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.2 | 4.7 | PID_ATM_PATHWAY | ATM pathway |
| 0.2 | 10.4 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.2 | 9.3 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
| 0.1 | 4.3 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 1.6 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 1.2 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 2.9 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.1 | 3.3 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.1 | 4.9 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.1 | 1.3 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 1.1 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 2.9 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 2.8 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.0 | 6.0 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 3.1 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.6 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 0.8 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 1.6 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 41.7 | REACTOME_KINESINS | Genes involved in Kinesins |
| 1.5 | 37.3 | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 1.3 | 10.7 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 1.3 | 32.9 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 1.0 | 99.5 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.9 | 2.6 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.7 | 19.5 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.6 | 7.5 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.5 | 15.5 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.4 | 16.0 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.4 | 14.2 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.4 | 10.8 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.3 | 7.1 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.3 | 15.7 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.3 | 5.0 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.3 | 9.9 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.3 | 4.7 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.2 | 11.8 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.2 | 10.7 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
| 0.2 | 2.5 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
| 0.2 | 4.3 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.2 | 10.6 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 1.3 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 4.3 | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
| 0.1 | 1.9 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.1 | 4.8 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.1 | 3.5 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 3.4 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 11.9 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 6.4 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 4.9 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 2.2 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
| 0.1 | 2.5 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 1.3 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
| 0.1 | 0.6 | REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 1.1 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.1 | 1.6 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.5 | REACTOME_COMPLEMENT_CASCADE | Genes involved in Complement cascade |
| 0.0 | 0.6 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 2.4 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.0 | 0.5 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.7 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.8 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.8 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.7 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.7 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.8 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
