Motif ID: Myf6
Z-value: 2.074
Transcription factors associated with Myf6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Myf6 | ENSMUSG00000035923.3 | Myf6 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.2 | 15.7 | GO:1900673 | olefin metabolic process(GO:1900673) |
| 4.7 | 14.2 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 4.7 | 41.9 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 4.3 | 25.6 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 4.0 | 12.1 | GO:0006601 | creatine biosynthetic process(GO:0006601) |
| 3.8 | 11.4 | GO:0061744 | motor behavior(GO:0061744) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 3.7 | 26.2 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 3.5 | 10.6 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
| 3.3 | 9.9 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 2.5 | 12.6 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
| 2.4 | 12.2 | GO:0032423 | regulation of mismatch repair(GO:0032423) |
| 2.0 | 16.4 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 2.0 | 9.9 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 1.9 | 7.6 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) lateral motor column neuron migration(GO:0097477) |
| 1.9 | 7.6 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 1.8 | 21.5 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 1.8 | 7.2 | GO:1905167 | astrocyte activation involved in immune response(GO:0002265) positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 1.8 | 5.3 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 1.7 | 5.0 | GO:0072720 | response to dithiothreitol(GO:0072720) |
| 1.6 | 4.9 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 1.6 | 9.8 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 1.6 | 8.1 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 1.4 | 2.8 | GO:0002725 | negative regulation of T cell cytokine production(GO:0002725) |
| 1.4 | 5.6 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
| 1.4 | 4.2 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
| 1.4 | 10.9 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 1.3 | 4.0 | GO:0007161 | calcium-independent cell-matrix adhesion(GO:0007161) |
| 1.3 | 5.3 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 1.3 | 11.5 | GO:0060373 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 1.2 | 31.5 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 1.2 | 7.0 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 1.1 | 11.3 | GO:0046959 | habituation(GO:0046959) |
| 1.1 | 7.6 | GO:0015879 | carnitine transport(GO:0015879) |
| 1.0 | 6.2 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 1.0 | 4.2 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 1.0 | 4.1 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 1.0 | 8.9 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 1.0 | 14.6 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.9 | 2.8 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.9 | 3.7 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.9 | 3.7 | GO:0015871 | choline transport(GO:0015871) |
| 0.9 | 7.0 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.9 | 4.3 | GO:0099645 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645) |
| 0.8 | 7.6 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.8 | 3.4 | GO:0097393 | post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582) |
| 0.8 | 3.3 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.8 | 4.8 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.8 | 5.4 | GO:0015862 | uridine transport(GO:0015862) |
| 0.8 | 2.3 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
| 0.8 | 2.3 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.8 | 2.3 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203) |
| 0.8 | 2.3 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.8 | 0.8 | GO:0021593 | rhombomere morphogenesis(GO:0021593) |
| 0.8 | 3.8 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 0.8 | 3.8 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.8 | 9.8 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.7 | 11.8 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.7 | 2.9 | GO:0061743 | motor learning(GO:0061743) |
| 0.7 | 6.2 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.7 | 4.1 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
| 0.7 | 2.0 | GO:1900365 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.7 | 13.4 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
| 0.7 | 2.0 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
| 0.7 | 2.0 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.6 | 2.5 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.6 | 2.5 | GO:0001692 | histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805) |
| 0.6 | 3.1 | GO:0072014 | proximal tubule development(GO:0072014) |
| 0.6 | 6.7 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.6 | 1.8 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.6 | 1.1 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.6 | 23.8 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.6 | 1.1 | GO:0032829 | regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) |
| 0.6 | 5.0 | GO:0097623 | potassium ion export across plasma membrane(GO:0097623) |
| 0.5 | 1.6 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) |
| 0.5 | 11.4 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.5 | 10.3 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.5 | 4.8 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.5 | 1.6 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 0.5 | 1.6 | GO:0031133 | regulation of axon diameter(GO:0031133) |
| 0.5 | 10.5 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.5 | 1.6 | GO:0015886 | heme transport(GO:0015886) |
| 0.5 | 1.6 | GO:0072236 | metanephric loop of Henle development(GO:0072236) |
| 0.5 | 13.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.5 | 2.0 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 0.5 | 2.5 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.5 | 8.3 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.5 | 2.9 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.5 | 2.9 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.5 | 3.3 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.5 | 2.3 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.5 | 2.3 | GO:0033625 | positive regulation of integrin activation(GO:0033625) |
| 0.5 | 2.8 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
| 0.5 | 1.4 | GO:0061357 | Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357) |
| 0.5 | 2.8 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.5 | 2.3 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.5 | 0.5 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.5 | 5.0 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.4 | 2.7 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 0.4 | 8.4 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.4 | 1.3 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.4 | 20.7 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.4 | 1.7 | GO:0050923 | regulation of negative chemotaxis(GO:0050923) |
| 0.4 | 6.3 | GO:0070571 | negative regulation of neuron projection regeneration(GO:0070571) |
| 0.4 | 2.9 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.4 | 1.3 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.4 | 5.8 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.4 | 0.8 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) |
| 0.4 | 1.2 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 0.4 | 7.8 | GO:0001553 | luteinization(GO:0001553) |
| 0.4 | 0.4 | GO:1901678 | iron coordination entity transport(GO:1901678) |
| 0.4 | 3.6 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 0.4 | 1.6 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
| 0.4 | 1.2 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
| 0.4 | 1.9 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.4 | 1.1 | GO:0060066 | oviduct development(GO:0060066) |
| 0.4 | 0.7 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
| 0.4 | 2.2 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 0.4 | 1.8 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.4 | 11.0 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.3 | 1.0 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.3 | 3.8 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
| 0.3 | 2.7 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.3 | 1.4 | GO:1905247 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247) |
| 0.3 | 0.7 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.3 | 4.3 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.3 | 28.2 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.3 | 1.6 | GO:0048505 | regulation of timing of cell differentiation(GO:0048505) |
| 0.3 | 39.5 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.3 | 1.2 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.3 | 0.9 | GO:0039533 | regulation of MDA-5 signaling pathway(GO:0039533) |
| 0.3 | 4.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.3 | 2.4 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
| 0.3 | 0.9 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) |
| 0.3 | 0.3 | GO:0046544 | development of secondary male sexual characteristics(GO:0046544) |
| 0.3 | 0.9 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 0.3 | 0.9 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.3 | 2.9 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.3 | 3.7 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.3 | 3.9 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.3 | 1.4 | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) |
| 0.3 | 1.1 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.3 | 0.3 | GO:0031587 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) |
| 0.3 | 0.5 | GO:0035696 | monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) |
| 0.3 | 1.0 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
| 0.3 | 1.0 | GO:0050913 | sensory perception of bitter taste(GO:0050913) |
| 0.3 | 2.0 | GO:0007182 | common-partner SMAD protein phosphorylation(GO:0007182) |
| 0.3 | 3.5 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.3 | 4.8 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.2 | 1.4 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.2 | 1.9 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.2 | 4.0 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.2 | 2.3 | GO:1900364 | regulation of mRNA polyadenylation(GO:1900363) negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.2 | 3.2 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.2 | 0.7 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.2 | 4.4 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.2 | 2.4 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 0.2 | 3.9 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.2 | 0.4 | GO:0030578 | PML body organization(GO:0030578) |
| 0.2 | 17.5 | GO:0007173 | epidermal growth factor receptor signaling pathway(GO:0007173) |
| 0.2 | 1.8 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.2 | 2.0 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.2 | 1.8 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.2 | 3.9 | GO:0050884 | neuromuscular process controlling posture(GO:0050884) |
| 0.2 | 0.6 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.2 | 1.3 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.2 | 1.3 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.2 | 2.3 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.2 | 2.8 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 0.2 | 1.7 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.2 | 0.9 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.2 | 1.1 | GO:1902177 | positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177) |
| 0.2 | 0.5 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.2 | 0.5 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.2 | 7.5 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.2 | 0.9 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.2 | 1.4 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.2 | 4.2 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.2 | 11.9 | GO:0030279 | negative regulation of ossification(GO:0030279) |
| 0.2 | 2.6 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
| 0.2 | 0.6 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.2 | 1.8 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.2 | 0.5 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
| 0.2 | 0.9 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.1 | 1.6 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 3.7 | GO:0009268 | response to pH(GO:0009268) |
| 0.1 | 12.7 | GO:0048709 | oligodendrocyte differentiation(GO:0048709) |
| 0.1 | 1.0 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.1 | 1.5 | GO:0042182 | ketone catabolic process(GO:0042182) |
| 0.1 | 0.8 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
| 0.1 | 1.1 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
| 0.1 | 0.7 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.1 | 3.5 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.1 | 1.3 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 3.3 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.1 | 0.6 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.1 | 1.2 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.1 | 8.2 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 0.5 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.1 | 2.3 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
| 0.1 | 0.5 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.1 | 1.3 | GO:0010759 | positive regulation of macrophage chemotaxis(GO:0010759) negative regulation of interleukin-12 production(GO:0032695) |
| 0.1 | 1.0 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.1 | 0.6 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.1 | 0.7 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 1.7 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 1.3 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.1 | 6.1 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.1 | 0.6 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
| 0.1 | 0.7 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 1.5 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism membrane organization(GO:0044803) |
| 0.1 | 0.4 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.1 | 0.9 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
| 0.1 | 2.0 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.1 | 0.4 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.1 | 0.2 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
| 0.1 | 2.0 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.1 | 0.7 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 1.4 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.1 | 1.9 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.1 | 0.4 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.1 | 1.1 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.1 | 0.5 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.1 | 0.9 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.1 | 5.4 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.1 | 0.5 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.1 | 2.2 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.1 | 0.7 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
| 0.1 | 1.1 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.1 | 5.6 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.1 | 0.6 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.1 | 2.9 | GO:0050818 | regulation of coagulation(GO:0050818) |
| 0.1 | 1.0 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.1 | 0.4 | GO:0051004 | plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004) |
| 0.1 | 1.6 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.1 | 3.5 | GO:0015992 | proton transport(GO:0015992) |
| 0.1 | 1.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.1 | 1.5 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 0.6 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
| 0.0 | 5.2 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.0 | 0.2 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.0 | 0.4 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 4.3 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.6 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.0 | 0.7 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 3.2 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.0 | 0.1 | GO:1903364 | positive regulation of cellular protein catabolic process(GO:1903364) |
| 0.0 | 0.5 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 1.3 | GO:0043407 | negative regulation of MAP kinase activity(GO:0043407) |
| 0.0 | 1.3 | GO:0045806 | negative regulation of endocytosis(GO:0045806) |
| 0.0 | 0.2 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.0 | 0.3 | GO:0043144 | snoRNA processing(GO:0043144) |
| 0.0 | 2.0 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.0 | 0.4 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity(GO:0032088) |
| 0.0 | 0.2 | GO:0006004 | fucose metabolic process(GO:0006004) glycoside catabolic process(GO:0016139) |
| 0.0 | 0.4 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
| 0.0 | 1.1 | GO:0006024 | glycosaminoglycan biosynthetic process(GO:0006024) |
| 0.0 | 0.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 1.0 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 0.0 | 1.3 | GO:0031638 | zymogen activation(GO:0031638) |
| 0.0 | 1.6 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 2.6 | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123) |
| 0.0 | 1.1 | GO:0030168 | platelet activation(GO:0030168) |
| 0.0 | 0.1 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
| 0.0 | 0.5 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.0 | 0.6 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
| 0.0 | 0.0 | GO:0045061 | positive thymic T cell selection(GO:0045059) thymic T cell selection(GO:0045061) |
| 0.0 | 0.1 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.0 | 1.6 | GO:0016485 | protein processing(GO:0016485) |
| 0.0 | 0.7 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.0 | 0.4 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.0 | 0.7 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.0 | 0.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.4 | 21.6 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 4.2 | 41.9 | GO:0045298 | tubulin complex(GO:0045298) |
| 3.9 | 15.7 | GO:0044307 | dendritic branch(GO:0044307) |
| 2.7 | 13.5 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 2.0 | 2.0 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 2.0 | 9.8 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 1.4 | 5.6 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 1.2 | 2.4 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 1.1 | 5.6 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
| 1.1 | 3.3 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 1.1 | 4.3 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 1.1 | 15.8 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 1.0 | 7.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.9 | 2.6 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.9 | 34.3 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.8 | 3.4 | GO:1990421 | subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707) |
| 0.8 | 4.1 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.8 | 3.9 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.8 | 11.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.7 | 4.9 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.6 | 50.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.6 | 2.3 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.6 | 2.3 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.6 | 2.8 | GO:1990357 | terminal web(GO:1990357) |
| 0.6 | 3.3 | GO:0016011 | dystroglycan complex(GO:0016011) |
| 0.5 | 4.8 | GO:0005883 | neurofilament(GO:0005883) |
| 0.5 | 8.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.5 | 7.1 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.5 | 5.3 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.5 | 2.8 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.4 | 3.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.4 | 15.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.4 | 6.0 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.4 | 1.2 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.4 | 2.0 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.4 | 2.0 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.4 | 1.6 | GO:0070820 | tertiary granule(GO:0070820) |
| 0.4 | 10.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.4 | 1.6 | GO:0097574 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
| 0.4 | 2.3 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.4 | 1.5 | GO:0019034 | viral replication complex(GO:0019034) |
| 0.4 | 11.9 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.3 | 1.0 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.3 | 2.3 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.3 | 1.0 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.3 | 3.1 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.3 | 1.9 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.3 | 5.7 | GO:0030673 | axolemma(GO:0030673) |
| 0.3 | 4.0 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.3 | 9.6 | GO:0031672 | A band(GO:0031672) |
| 0.3 | 5.9 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.3 | 4.1 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.3 | 33.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.3 | 7.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.3 | 1.3 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.3 | 2.8 | GO:0031045 | dense core granule(GO:0031045) |
| 0.3 | 4.9 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 25.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.2 | 3.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.2 | 2.8 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.2 | 0.5 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.2 | 1.8 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.2 | 2.5 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.2 | 3.6 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.2 | 0.7 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
| 0.2 | 1.3 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.2 | 11.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.2 | 2.4 | GO:0043219 | lateral loop(GO:0043219) |
| 0.2 | 2.9 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.2 | 1.9 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.2 | 1.0 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.2 | 8.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 2.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.2 | 1.6 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 10.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.1 | 46.4 | GO:0097060 | synaptic membrane(GO:0097060) |
| 0.1 | 7.6 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 9.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 15.7 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 1.8 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 0.5 | GO:0005745 | m-AAA complex(GO:0005745) |
| 0.1 | 8.7 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 0.6 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.1 | 5.2 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 5.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 7.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 1.7 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 1.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.1 | 2.6 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.1 | 2.2 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 5.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 2.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 1.6 | GO:0005776 | autophagosome(GO:0005776) |
| 0.1 | 1.3 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 1.3 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 0.6 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 4.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 0.5 | GO:0043218 | compact myelin(GO:0043218) |
| 0.1 | 0.7 | GO:0042641 | actomyosin(GO:0042641) |
| 0.1 | 2.0 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 0.7 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 0.5 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.1 | 1.0 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 2.6 | GO:0009986 | cell surface(GO:0009986) |
| 0.1 | 5.8 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 0.9 | GO:0030660 | Golgi-associated vesicle membrane(GO:0030660) |
| 0.1 | 1.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 3.7 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.1 | 3.5 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 2.3 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.4 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.6 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 1.6 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 23.3 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 1.0 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 1.2 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 1.3 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 2.6 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 1.9 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 1.8 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.7 | 26.2 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 7.5 | 22.6 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 6.3 | 18.9 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 6.0 | 41.9 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 4.5 | 13.6 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 3.5 | 38.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 3.3 | 13.0 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 2.7 | 13.5 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 2.6 | 15.7 | GO:1904315 | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 2.4 | 7.2 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 2.0 | 9.8 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 1.9 | 7.6 | GO:0015226 | amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) |
| 1.6 | 1.6 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 1.6 | 11.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 1.6 | 8.1 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 1.4 | 8.2 | GO:0045545 | syndecan binding(GO:0045545) |
| 1.2 | 3.7 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 1.2 | 3.5 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
| 1.0 | 16.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 1.0 | 17.9 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 1.0 | 4.9 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 1.0 | 7.7 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 1.0 | 6.7 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.9 | 2.8 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.9 | 3.7 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.9 | 6.4 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.9 | 7.8 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.8 | 7.4 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.8 | 2.5 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.8 | 3.2 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.8 | 3.2 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.7 | 2.9 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.7 | 4.3 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.7 | 7.6 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.7 | 4.0 | GO:0045340 | mercury ion binding(GO:0045340) |
| 0.7 | 2.0 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.7 | 13.0 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.6 | 5.8 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.6 | 2.6 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.6 | 3.7 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.6 | 1.8 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.6 | 2.4 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.6 | 2.9 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.6 | 2.9 | GO:2001070 | starch binding(GO:2001070) |
| 0.6 | 2.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.6 | 4.0 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.6 | 3.9 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.5 | 2.2 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.5 | 1.6 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.5 | 8.5 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.5 | 1.6 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.5 | 1.6 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.5 | 3.1 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.5 | 12.1 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.5 | 19.6 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.5 | 1.5 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.5 | 3.4 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.5 | 1.9 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.5 | 4.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.4 | 13.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.4 | 23.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.4 | 10.6 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.4 | 1.7 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 0.4 | 1.3 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.4 | 4.9 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.4 | 6.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.4 | 3.9 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.4 | 8.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.4 | 1.2 | GO:0004127 | cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041) |
| 0.4 | 12.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.4 | 2.3 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.4 | 4.6 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.4 | 1.9 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.4 | 3.4 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.4 | 1.1 | GO:0005119 | smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) |
| 0.4 | 1.8 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.4 | 3.5 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.3 | 5.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.3 | 3.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.3 | 4.1 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.3 | 1.3 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.3 | 1.3 | GO:0070492 | oligosaccharide binding(GO:0070492) |
| 0.3 | 4.1 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.3 | 5.8 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.3 | 11.4 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.3 | 3.1 | GO:0015250 | water channel activity(GO:0015250) |
| 0.3 | 10.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.3 | 1.5 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.3 | 0.9 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 0.3 | 1.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.3 | 4.6 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.3 | 1.9 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.3 | 1.6 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.3 | 3.2 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.3 | 7.6 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.2 | 4.4 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.2 | 1.4 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.2 | 6.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 1.9 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 1.0 | GO:0071074 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.2 | 8.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 0.9 | GO:0052743 | inositol tetrakisphosphate phosphatase activity(GO:0052743) |
| 0.2 | 2.8 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.2 | 2.3 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.2 | 0.7 | GO:2001069 | glycogen binding(GO:2001069) |
| 0.2 | 2.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 0.7 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.2 | 5.3 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.2 | 2.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.2 | 5.8 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.2 | 4.0 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.2 | 5.4 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.2 | 15.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.2 | 0.8 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
| 0.2 | 0.5 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.2 | 4.6 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.2 | 0.5 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.2 | 15.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.2 | 7.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.2 | 5.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.2 | 2.9 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.2 | 17.0 | GO:0016247 | channel regulator activity(GO:0016247) |
| 0.2 | 0.5 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
| 0.2 | 1.6 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.2 | 0.6 | GO:0004528 | phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529) |
| 0.1 | 1.3 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.1 | 4.8 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 0.4 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.1 | 1.6 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 0.9 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.1 | 0.9 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
| 0.1 | 2.0 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.1 | 1.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 2.1 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 3.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.9 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 0.5 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.1 | 1.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 1.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 1.0 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 2.2 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.1 | 2.2 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.1 | 1.9 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 0.4 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.1 | 12.9 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.1 | 13.0 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 0.5 | GO:0009374 | biotin binding(GO:0009374) |
| 0.1 | 3.0 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 1.6 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 1.0 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.1 | 4.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 0.7 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 14.0 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
| 0.1 | 0.2 | GO:0015928 | alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928) |
| 0.1 | 2.5 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 1.3 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.1 | 5.6 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.1 | 2.6 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 20.5 | GO:0003779 | actin binding(GO:0003779) |
| 0.1 | 0.2 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.1 | 5.2 | GO:0016798 | hydrolase activity, acting on glycosyl bonds(GO:0016798) |
| 0.1 | 0.6 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 0.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.3 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 1.2 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.1 | 1.5 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.1 | 0.8 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 0.4 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.0 | 1.6 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.9 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 1.0 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 1.6 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 2.0 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 0.3 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 1.1 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 0.7 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 1.3 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 1.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 3.1 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.0 | 0.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.5 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.8 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.0 | 0.8 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.0 | 1.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.8 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 1.1 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.1 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 1.2 | GO:0004536 | deoxyribonuclease activity(GO:0004536) |
| 0.0 | 0.7 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.0 | 4.5 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.0 | 0.5 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.4 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 0.3 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 0.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 2.0 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 1.5 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 0.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.1 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 1.4 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.1 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.0 | 0.5 | GO:0008083 | growth factor activity(GO:0008083) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 36.8 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 1.4 | 8.3 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
| 1.2 | 18.4 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.9 | 30.9 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.6 | 13.1 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.5 | 14.8 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.4 | 2.5 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
| 0.3 | 11.8 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.3 | 2.9 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.3 | 12.0 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.2 | 33.3 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 1.8 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.2 | 3.5 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.2 | 5.0 | PID_EPO_PATHWAY | EPO signaling pathway |
| 0.2 | 6.1 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.2 | 7.5 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.2 | 4.5 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.2 | 6.2 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.2 | 2.2 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.2 | 1.6 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.2 | 2.0 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 2.6 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.1 | 1.3 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 1.7 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.1 | 4.0 | PID_IL1_PATHWAY | IL1-mediated signaling events |
| 0.1 | 5.1 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 1.9 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 6.2 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.1 | 4.9 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 10.4 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 6.3 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 7.2 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 0.5 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 3.8 | SIG_BCR_SIGNALING_PATHWAY | Members of the BCR signaling pathway |
| 0.1 | 2.0 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 8.9 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.1 | 1.1 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.1 | 2.2 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.1 | 0.9 | PID_IL27_PATHWAY | IL27-mediated signaling events |
| 0.1 | 1.4 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.1 | 1.9 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 2.8 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.1 | 2.6 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.1 | 2.0 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.1 | 1.3 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
| 0.1 | 2.0 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.1 | 0.7 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 1.4 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 2.2 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.5 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 1.3 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.1 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.2 | PID_HIV_NEF_PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 1.9 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.3 | PID_ARF6_PATHWAY | Arf6 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.5 | 38.5 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 2.7 | 5.3 | REACTOME_SHC_MEDIATED_SIGNALLING | Genes involved in SHC-mediated signalling |
| 1.3 | 7.6 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 1.2 | 52.0 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 1.2 | 26.9 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 1.2 | 9.2 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 1.0 | 25.7 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 1.0 | 12.3 | REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 1.0 | 15.8 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.9 | 11.6 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.9 | 24.0 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.8 | 18.4 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.8 | 18.0 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.7 | 9.0 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.7 | 23.6 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.7 | 11.4 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.6 | 30.9 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.6 | 0.6 | REACTOME_SIGNALING_BY_NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.6 | 4.0 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
| 0.6 | 5.6 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.6 | 6.1 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.5 | 4.8 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.5 | 15.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.5 | 4.1 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.4 | 4.2 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
| 0.4 | 20.7 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.4 | 15.7 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.4 | 3.2 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.3 | 6.9 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.3 | 12.1 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.3 | 2.6 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
| 0.3 | 3.7 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.3 | 2.6 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.3 | 7.6 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.2 | 2.0 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.2 | 1.6 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.2 | 0.9 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.2 | 4.6 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.2 | 4.8 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.2 | 1.3 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.2 | 3.7 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.2 | 4.3 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.2 | 2.0 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 2.3 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.2 | 1.6 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.2 | 1.8 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.2 | 2.6 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 3.1 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 0.8 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 4.0 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 8.6 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
| 0.1 | 0.7 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
| 0.1 | 1.1 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 1.5 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 8.8 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 3.4 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 4.6 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 1.1 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 2.2 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 1.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 1.0 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.1 | 3.3 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 2.2 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.1 | 0.7 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 4.3 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.1 | 1.4 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 0.2 | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
| 0.1 | 1.1 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 2.2 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 10.6 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 1.3 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 8.1 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 4.2 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 1.0 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.0 | 2.0 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.6 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.5 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 2.8 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.9 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.5 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.7 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.6 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 2.3 | REACTOME_DNA_REPAIR | Genes involved in DNA Repair |
| 0.0 | 2.5 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 0.1 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
