Motif ID: Myf6

Z-value: 2.074


Transcription factors associated with Myf6:

Gene SymbolEntrez IDGene Name
Myf6 ENSMUSG00000035923.3 Myf6



Activity profile for motif Myf6.

activity profile for motif Myf6


Sorted Z-values histogram for motif Myf6

Sorted Z-values for motif Myf6



Network of associatons between targets according to the STRING database.



First level regulatory network of Myf6

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_9771018 25.189 ENSMUST00000110969.3
 Fam155a
family with sequence similarity 155, member A
chr9_-_112185939 23.567 ENSMUST00000070218.5
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr18_-_36197343 22.584 ENSMUST00000115713.1
ENSMUST00000115712.1
 Nrg2

neuregulin 2

chr8_+_125995102 21.596 ENSMUST00000046765.8
 Kcnk1
potassium channel, subfamily K, member 1
chr3_+_118433797 21.174 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
 Gm26871



predicted gene, 26871



chr16_+_91269759 20.166 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr9_+_27790947 17.788 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr15_-_66812593 17.011 ENSMUST00000100572.3
 Sla
src-like adaptor
chr11_+_50602072 16.510 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr16_+_41532999 15.729 ENSMUST00000099761.3
 Lsamp
limbic system-associated membrane protein
chr5_+_30588078 12.370 ENSMUST00000066295.2
 Kcnk3
potassium channel, subfamily K, member 3
chr2_-_122611238 12.110 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chrX_+_73503074 11.571 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
 Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr1_-_3671498 11.543 ENSMUST00000070533.4
 Xkr4
X Kell blood group precursor related family member 4
chr18_+_65873478 11.427 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr11_+_104231573 11.392 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
 Mapt


microtubule-associated protein tau


chr6_-_126740151 11.168 ENSMUST00000112242.1
 Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr11_-_6065538 10.577 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr16_-_67620880 10.565 ENSMUST00000114292.1
ENSMUST00000120898.1
 Cadm2

cell adhesion molecule 2

chr2_-_104409992 10.564 ENSMUST00000149466.1
ENSMUST00000139015.1
 D430041D05Rik

RIKEN cDNA D430041D05 gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 272 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.7 41.9 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.3 39.5 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
1.2 31.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.3 28.2 GO:0030032 lamellipodium assembly(GO:0030032)
3.7 26.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
4.3 25.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.6 23.8 GO:0034605 cellular response to heat(GO:0034605)
1.8 21.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4 20.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 17.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
2.0 16.4 GO:0030322 stabilization of membrane potential(GO:0030322)
5.2 15.7 GO:1900673 olefin metabolic process(GO:1900673)
1.0 14.6 GO:0030574 collagen catabolic process(GO:0030574)
4.7 14.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 13.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.7 13.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 12.7 GO:0048709 oligodendrocyte differentiation(GO:0048709)
2.5 12.6 GO:0035405 histone-threonine phosphorylation(GO:0035405)
2.4 12.2 GO:0032423 regulation of mismatch repair(GO:0032423)
4.0 12.1 GO:0006601 creatine biosynthetic process(GO:0006601)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 50.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 46.4 GO:0097060 synaptic membrane(GO:0097060)
4.2 41.9 GO:0045298 tubulin complex(GO:0045298)
0.9 34.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 33.1 GO:0031225 anchored component of membrane(GO:0031225)
0.2 25.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 23.3 GO:0005887 integral component of plasma membrane(GO:0005887)
5.4 21.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.1 15.8 GO:1902711 GABA-A receptor complex(GO:1902711)
3.9 15.7 GO:0044307 dendritic branch(GO:0044307)
0.1 15.7 GO:0005903 brush border(GO:0005903)
0.4 15.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
2.7 13.5 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.4 11.9 GO:0051233 spindle midzone(GO:0051233)
0.2 11.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.8 11.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 10.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 10.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
2.0 9.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.3 9.6 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 203 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.0 41.9 GO:0099609 microtubule lateral binding(GO:0099609)
3.5 38.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
8.7 26.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.4 23.7 GO:0046875 ephrin receptor binding(GO:0046875)
7.5 22.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 20.5 GO:0003779 actin binding(GO:0003779)
0.5 19.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
6.3 18.9 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
1.0 17.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 17.0 GO:0016247 channel regulator activity(GO:0016247)
1.0 16.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
2.6 15.7 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 15.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 15.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 14.0 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
4.5 13.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
2.7 13.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 13.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
3.3 13.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.7 13.0 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 36.8 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 33.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.9 30.9 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
1.2 18.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.5 14.8 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.6 13.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.3 12.0 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.3 11.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 10.4 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 8.9 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
1.4 8.3 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.2 7.5 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 7.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 6.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.2 6.2 ST_ADRENERGIC Adrenergic Pathway
0.1 6.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.2 6.1 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 5.1 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2 5.0 PID_EPO_PATHWAY EPO signaling pathway
0.1 4.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 52.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
5.5 38.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.6 30.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
1.2 26.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.0 25.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.9 24.0 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.7 23.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.4 20.7 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.8 18.4 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.8 18.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.0 15.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.4 15.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.5 15.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.0 12.3 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.3 12.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.9 11.6 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.7 11.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 10.6 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
1.2 9.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7 9.0 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors