Motif ID: Myod1
Z-value: 0.480
Transcription factors associated with Myod1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Myod1 | ENSMUSG00000009471.3 | Myod1 |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 168 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 6.5 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.3 | 3.7 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.8 | 3.2 | GO:0060032 | notochord regression(GO:0060032) |
| 1.0 | 3.1 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.3 | 2.9 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742) |
| 0.3 | 2.1 | GO:0097473 | cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
| 0.1 | 2.0 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.1 | 1.8 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.2 | 1.7 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.2 | 1.7 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 1.7 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.4 | 1.6 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
| 0.1 | 1.6 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.0 | 1.4 | GO:0030010 | establishment of cell polarity(GO:0030010) |
| 0.3 | 1.3 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.2 | 1.3 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.2 | 1.3 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.2 | 1.3 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
| 0.1 | 1.3 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 0.1 | 1.3 | GO:0010831 | positive regulation of myotube differentiation(GO:0010831) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 70 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 3.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 3.8 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.1 | 3.4 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.2 | 3.2 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 3.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 2.8 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 2.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 1.8 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 1.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 1.6 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 1.5 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 1.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.4 | 1.3 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.1 | 1.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 1.3 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 1.2 | GO:0043219 | lateral loop(GO:0043219) |
| 0.1 | 1.2 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 1.2 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 1.2 | GO:0002102 | podosome(GO:0002102) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 101 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 6.5 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.2 | 4.0 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 4.0 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 1.1 | 3.4 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.1 | 3.4 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 3.4 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 3.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 2.9 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 2.3 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.6 | 1.7 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.0 | 1.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 1.6 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.0 | 1.6 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.4 | 1.3 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
| 0.1 | 1.3 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 1.3 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.0 | 1.3 | GO:0017022 | myosin binding(GO:0017022) |
| 0.1 | 1.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 1.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 1.1 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 37 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.3 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 4.7 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 3.3 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 2.7 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 2.2 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 2.0 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 1.9 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.3 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 1.3 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.0 | 1.3 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.0 | 1.3 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 1.2 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 1.2 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.1 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.9 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.9 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.9 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.0 | 0.9 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.1 | 0.8 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 0.8 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 48 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.7 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 3.4 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.3 | 3.1 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 2.5 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 2.5 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.1 | 2.3 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 2.1 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 2.1 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.1 | 1.8 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.1 | 1.8 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 1.7 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.4 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 1.3 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 1.3 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 1.2 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 1.1 | REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION | Genes involved in Incretin Synthesis, Secretion, and Inactivation |
| 0.0 | 1.1 | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 1.0 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 0.9 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 0.9 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
