Motif ID: Mzf1
Z-value: 0.993
Transcription factors associated with Mzf1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Mzf1 | ENSMUSG00000030380.10 | Mzf1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Mzf1 | mm10_v2_chr7_-_13053684_13053684 | 0.19 | 1.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 6.1 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
| 1.8 | 5.4 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 1.1 | 4.3 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 1.0 | 13.5 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
| 1.0 | 3.1 | GO:0060596 | mammary placode formation(GO:0060596) |
| 1.0 | 2.9 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.9 | 2.7 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 0.8 | 3.9 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.7 | 2.7 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
| 0.7 | 2.7 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.6 | 2.5 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
| 0.6 | 1.9 | GO:0030070 | insulin processing(GO:0030070) |
| 0.6 | 5.0 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.6 | 3.1 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 0.6 | 1.8 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.6 | 3.0 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.6 | 4.2 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.6 | 1.7 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
| 0.6 | 3.5 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.6 | 1.7 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
| 0.6 | 1.7 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
| 0.6 | 5.0 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.6 | 2.2 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.6 | 2.8 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
| 0.6 | 1.7 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.5 | 1.6 | GO:0009826 | unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.5 | 3.8 | GO:0099645 | protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645) |
| 0.5 | 1.6 | GO:1904742 | protein poly-ADP-ribosylation(GO:0070212) protein auto-ADP-ribosylation(GO:0070213) regulation of telomeric DNA binding(GO:1904742) |
| 0.5 | 2.7 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.5 | 1.6 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.5 | 2.1 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
| 0.5 | 1.0 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
| 0.5 | 4.4 | GO:0097623 | potassium ion export across plasma membrane(GO:0097623) |
| 0.5 | 2.0 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.5 | 8.1 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.5 | 1.9 | GO:0099527 | postsynapse to nucleus signaling pathway(GO:0099527) |
| 0.5 | 2.7 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.5 | 5.5 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
| 0.4 | 2.2 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.4 | 1.3 | GO:0021649 | vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) |
| 0.4 | 1.3 | GO:0070428 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) |
| 0.4 | 1.3 | GO:1904058 | positive regulation of sensory perception of pain(GO:1904058) cholangiocyte proliferation(GO:1990705) |
| 0.4 | 2.1 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.4 | 2.1 | GO:0010991 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.4 | 0.8 | GO:0003404 | optic vesicle morphogenesis(GO:0003404) |
| 0.4 | 3.9 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 0.4 | 2.3 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.4 | 1.5 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.4 | 1.1 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
| 0.4 | 2.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.4 | 3.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.4 | 0.4 | GO:0071317 | cellular response to isoquinoline alkaloid(GO:0071317) |
| 0.4 | 1.8 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.4 | 5.0 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.4 | 2.5 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.3 | 6.3 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.3 | 2.7 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.3 | 0.7 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.3 | 2.0 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.3 | 2.0 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.3 | 1.3 | GO:0030860 | regulation of polarized epithelial cell differentiation(GO:0030860) |
| 0.3 | 1.0 | GO:0014916 | regulation of lung blood pressure(GO:0014916) |
| 0.3 | 1.3 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
| 0.3 | 1.3 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
| 0.3 | 0.6 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) |
| 0.3 | 1.0 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203) |
| 0.3 | 1.3 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) |
| 0.3 | 2.8 | GO:0098907 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907) |
| 0.3 | 1.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.3 | 1.2 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.3 | 2.6 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.3 | 1.7 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.3 | 1.1 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.3 | 5.4 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.3 | 2.8 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.3 | 0.9 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
| 0.3 | 1.4 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.3 | 0.3 | GO:0033292 | T-tubule organization(GO:0033292) |
| 0.3 | 1.6 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 0.3 | 1.6 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
| 0.3 | 1.9 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.3 | 1.5 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.3 | 1.0 | GO:0045759 | negative regulation of action potential(GO:0045759) |
| 0.2 | 0.7 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 0.2 | 0.2 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
| 0.2 | 2.5 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.2 | 0.7 | GO:0009446 | putrescine biosynthetic process(GO:0009446) |
| 0.2 | 0.9 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.2 | 1.4 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.2 | 1.8 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.2 | 0.9 | GO:0044330 | canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
| 0.2 | 0.9 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.2 | 2.3 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.2 | 2.7 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.2 | 3.1 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.2 | 0.6 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.2 | 1.4 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.2 | 0.8 | GO:0002069 | columnar/cuboidal epithelial cell maturation(GO:0002069) |
| 0.2 | 1.4 | GO:1990416 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.2 | 0.6 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.2 | 4.0 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.2 | 1.2 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.2 | 1.6 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.2 | 2.7 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.2 | 1.5 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.2 | 1.5 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.2 | 2.6 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.2 | 3.0 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.2 | 1.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.2 | 0.7 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
| 0.2 | 0.7 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
| 0.2 | 2.6 | GO:0001956 | positive regulation of neurotransmitter secretion(GO:0001956) |
| 0.2 | 1.1 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) |
| 0.2 | 0.9 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 0.2 | 2.9 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.2 | 0.9 | GO:1902732 | positive regulation of chondrocyte proliferation(GO:1902732) |
| 0.2 | 0.5 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.2 | 1.8 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.2 | 1.0 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.2 | 0.8 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.2 | 2.0 | GO:0015732 | prostaglandin transport(GO:0015732) |
| 0.2 | 3.0 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.2 | 0.6 | GO:0051305 | chromosome movement towards spindle pole(GO:0051305) |
| 0.2 | 0.6 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.2 | 0.8 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.2 | 0.6 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.2 | 9.8 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.2 | 1.1 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.2 | 1.4 | GO:1900194 | receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 0.4 | GO:0097274 | urea homeostasis(GO:0097274) |
| 0.1 | 1.4 | GO:0010572 | positive regulation of platelet activation(GO:0010572) negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642) |
| 0.1 | 3.0 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.1 | 1.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.7 | GO:0031642 | negative regulation of myelination(GO:0031642) cellular response to cold(GO:0070417) |
| 0.1 | 1.5 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.1 | 1.8 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 1.0 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.1 | 0.5 | GO:0001787 | natural killer cell proliferation(GO:0001787) |
| 0.1 | 0.3 | GO:0071806 | intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806) |
| 0.1 | 1.4 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.1 | 1.2 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.1 | 1.1 | GO:0001964 | startle response(GO:0001964) |
| 0.1 | 0.4 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.1 | 0.7 | GO:0045900 | negative regulation of translational elongation(GO:0045900) |
| 0.1 | 1.5 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 1.7 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 0.2 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
| 0.1 | 0.5 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 0.1 | 0.6 | GO:1903223 | positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.1 | 1.0 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 0.3 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.1 | 0.5 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 0.1 | 0.5 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) negative regulation of vacuolar transport(GO:1903336) |
| 0.1 | 0.4 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.1 | 1.4 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 0.3 | GO:0060023 | soft palate development(GO:0060023) |
| 0.1 | 0.3 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.1 | 0.7 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 0.1 | GO:0072367 | regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368) |
| 0.1 | 0.7 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.1 | 0.9 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 0.7 | GO:0048702 | embryonic neurocranium morphogenesis(GO:0048702) |
| 0.1 | 2.6 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.1 | 0.5 | GO:0034351 | negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.1 | 0.9 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
| 0.1 | 0.5 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.1 | 1.8 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
| 0.1 | 0.3 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.1 | 0.3 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.1 | 0.2 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.1 | 0.3 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.1 | 0.3 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.1 | 0.8 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
| 0.1 | 0.2 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.1 | 1.0 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.1 | 0.6 | GO:0023035 | CD40 signaling pathway(GO:0023035) |
| 0.1 | 0.7 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.1 | 0.5 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.1 | 0.5 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 0.6 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.1 | 0.3 | GO:1903966 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 0.1 | 0.2 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.1 | 0.9 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.1 | 2.0 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 1.7 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.1 | 0.8 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 0.2 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 0.1 | 0.5 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
| 0.1 | 0.5 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.1 | 1.1 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 1.2 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.1 | 0.9 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 0.2 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 0.1 | 0.8 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.1 | 0.2 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.1 | 1.5 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.1 | 0.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 0.6 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 0.4 | GO:1903846 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.1 | 0.6 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 1.3 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.1 | 1.2 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.1 | 1.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.1 | 0.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.1 | 0.7 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.1 | 0.3 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.1 | 0.2 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.1 | 0.6 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.1 | 0.4 | GO:0043084 | penile erection(GO:0043084) |
| 0.1 | 0.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.1 | 0.4 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.0 | 1.7 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
| 0.0 | 0.9 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.0 | 0.4 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
| 0.0 | 1.5 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.7 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.0 | 0.9 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 0.1 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 0.0 | 0.5 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 0.4 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.0 | 0.6 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.0 | 0.9 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.0 | 1.8 | GO:0030071 | regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099) |
| 0.0 | 0.1 | GO:0039533 | regulation of MDA-5 signaling pathway(GO:0039533) |
| 0.0 | 0.5 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 0.3 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 0.0 | 0.3 | GO:0097501 | stress response to metal ion(GO:0097501) |
| 0.0 | 0.2 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
| 0.0 | 0.4 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 0.2 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.0 | 0.8 | GO:0048741 | skeletal muscle fiber development(GO:0048741) |
| 0.0 | 1.6 | GO:1903078 | positive regulation of protein localization to plasma membrane(GO:1903078) |
| 0.0 | 1.5 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.2 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.0 | 0.1 | GO:2000812 | regulation of barbed-end actin filament capping(GO:2000812) |
| 0.0 | 0.6 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 0.0 | 1.1 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.0 | 1.7 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.6 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.0 | 0.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.5 | GO:0014044 | Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.0 | 1.4 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
| 0.0 | 1.3 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 0.3 | GO:2000580 | regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.0 | 0.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.3 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 0.3 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.0 | 0.1 | GO:0010985 | negative regulation of lipoprotein particle clearance(GO:0010985) negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.0 | 0.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.0 | 0.3 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.0 | 0.3 | GO:0001675 | acrosome assembly(GO:0001675) intermediate filament organization(GO:0045109) |
| 0.0 | 1.6 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.0 | 0.3 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
| 0.0 | 0.5 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 0.4 | GO:0009072 | aromatic amino acid family metabolic process(GO:0009072) |
| 0.0 | 0.4 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.0 | 2.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.5 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 0.4 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.0 | 0.6 | GO:0051966 | regulation of synaptic transmission, glutamatergic(GO:0051966) |
| 0.0 | 0.4 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
| 0.0 | 0.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.1 | GO:0002922 | positive regulation of humoral immune response(GO:0002922) |
| 0.0 | 0.1 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.0 | 0.2 | GO:0002031 | G-protein coupled receptor internalization(GO:0002031) |
| 0.0 | 0.6 | GO:0006625 | protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 1.0 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.0 | 0.3 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.0 | 0.1 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.0 | 0.0 | GO:0007354 | zygotic determination of anterior/posterior axis, embryo(GO:0007354) |
| 0.0 | 0.7 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.0 | 0.3 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
| 0.0 | 0.0 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.0 | 1.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.0 | 0.2 | GO:0014823 | response to activity(GO:0014823) |
| 0.0 | 0.1 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 0.0 | 0.1 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.0 | 0.3 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.0 | 0.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.5 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.0 | 0.1 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.0 | 0.1 | GO:2001223 | negative regulation of neuron migration(GO:2001223) |
| 0.0 | 0.1 | GO:0070200 | establishment of protein localization to telomere(GO:0070200) |
| 0.0 | 1.4 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
| 0.0 | 0.1 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
| 0.0 | 0.1 | GO:0080184 | response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184) |
| 0.0 | 0.3 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.2 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.3 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.0 | 1.7 | GO:0050821 | protein stabilization(GO:0050821) |
| 0.0 | 0.0 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.0 | 0.5 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.0 | 0.3 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 0.2 | GO:1902170 | cellular response to reactive nitrogen species(GO:1902170) |
| 0.0 | 0.1 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.0 | 0.1 | GO:0035878 | nail development(GO:0035878) |
| 0.0 | 0.2 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
| 0.0 | 0.4 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
| 0.0 | 0.2 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
| 0.0 | 0.1 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.0 | 0.1 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 0.0 | 0.4 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 0.2 | GO:0006415 | translational termination(GO:0006415) |
| 0.0 | 0.1 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.0 | 0.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.1 | GO:0032785 | negative regulation of DNA-templated transcription, elongation(GO:0032785) |
| 0.0 | 0.1 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 0.0 | GO:0019405 | alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.0 | 0.0 | GO:0046929 | negative regulation of neurotransmitter secretion(GO:0046929) |
| 0.0 | 3.0 | GO:0051260 | protein homooligomerization(GO:0051260) |
| 0.0 | 0.1 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.1 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 0.1 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 3.5 | GO:0090537 | CERF complex(GO:0090537) |
| 0.8 | 15.6 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.8 | 3.8 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.8 | 3.0 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.6 | 1.7 | GO:0044302 | dentate gyrus mossy fiber(GO:0044302) |
| 0.6 | 2.3 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.6 | 0.6 | GO:0099572 | postsynaptic specialization(GO:0099572) |
| 0.5 | 7.0 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.4 | 3.9 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.4 | 6.5 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.4 | 3.3 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.4 | 1.4 | GO:0031673 | H zone(GO:0031673) |
| 0.3 | 1.3 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.3 | 13.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.3 | 4.0 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.3 | 1.7 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.3 | 2.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.3 | 4.7 | GO:0031045 | dense core granule(GO:0031045) |
| 0.3 | 0.8 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.3 | 2.9 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.3 | 1.8 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.3 | 1.0 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.2 | 2.7 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.2 | 5.8 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.2 | 15.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.2 | 1.1 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.2 | 3.2 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 5.0 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.2 | 1.1 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 1.8 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.2 | 2.5 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 1.4 | GO:0097413 | Lewy body(GO:0097413) |
| 0.2 | 1.9 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.2 | 1.7 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.2 | 1.1 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.2 | 0.3 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.2 | 2.3 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.2 | 2.0 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 1.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 0.3 | GO:0001940 | female pronucleus(GO:0001939) male pronucleus(GO:0001940) |
| 0.1 | 4.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 6.1 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 3.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 2.2 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 1.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 1.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.3 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.1 | 0.4 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.1 | 0.8 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 1.1 | GO:0098845 | postsynaptic endosome(GO:0098845) |
| 0.1 | 1.8 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 34.4 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.1 | 0.3 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.1 | 1.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 2.3 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.1 | 0.5 | GO:0030891 | VCB complex(GO:0030891) |
| 0.1 | 1.1 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 0.5 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 1.7 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.7 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.1 | 3.1 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 3.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 0.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 5.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 0.7 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.1 | 2.3 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 2.9 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 0.4 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.1 | 0.5 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.1 | 1.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 5.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 0.1 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 1.1 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 1.2 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 0.5 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 0.6 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 0.1 | 0.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 2.2 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 0.3 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.1 | 0.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.6 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 0.8 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 1.3 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 2.4 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 0.2 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 9.5 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.1 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 0.2 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.0 | 0.2 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.1 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
| 0.0 | 0.5 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.0 | 5.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 0.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.5 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 1.4 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.5 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.6 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.2 | GO:0005638 | lamin filament(GO:0005638) |
| 0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.4 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 1.3 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.3 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.9 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.0 | 0.9 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.0 | 2.2 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.2 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.0 | 0.7 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.0 | 1.2 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.2 | GO:0098797 | plasma membrane protein complex(GO:0098797) |
| 0.0 | 0.2 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 2.3 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.5 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 0.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.6 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.0 | 1.4 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.3 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 1.5 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.3 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 3.0 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.1 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.0 | 0.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.1 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.0 | 1.3 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 0.6 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.8 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 1.6 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.3 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 0.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 2.0 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.3 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.1 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.0 | 2.5 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 1.5 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.1 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 0.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.7 | GO:0001726 | ruffle(GO:0001726) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 11.8 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 1.4 | 4.3 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 1.3 | 5.0 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 1.2 | 3.5 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
| 1.0 | 3.0 | GO:0070905 | serine binding(GO:0070905) |
| 1.0 | 3.0 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 1.0 | 2.9 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.9 | 2.8 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.8 | 5.0 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.7 | 2.9 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 0.7 | 10.0 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.7 | 2.0 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.6 | 3.8 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.6 | 2.5 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.6 | 2.4 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.6 | 1.7 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.6 | 3.4 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.6 | 1.7 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.5 | 9.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.5 | 3.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.5 | 4.8 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.5 | 1.8 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.4 | 2.2 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.4 | 1.3 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.4 | 2.1 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.4 | 3.3 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.4 | 1.2 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 0.4 | 1.6 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.4 | 2.3 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.4 | 1.5 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.4 | 1.5 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.4 | 1.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.3 | 3.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.3 | 1.0 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.3 | 1.8 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.3 | 4.8 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.3 | 1.8 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.3 | 1.2 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.3 | 3.0 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.3 | 0.9 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.3 | 2.0 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
| 0.3 | 4.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.3 | 1.3 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 0.3 | 1.5 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.2 | 0.7 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
| 0.2 | 2.2 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.2 | 1.7 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.2 | 1.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 1.3 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.2 | 1.1 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.2 | 2.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.2 | 1.3 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.2 | 0.6 | GO:0030519 | snoRNP binding(GO:0030519) |
| 0.2 | 1.0 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.2 | 0.8 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.2 | 8.1 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.2 | 1.1 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
| 0.2 | 1.3 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.2 | 0.8 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.2 | 1.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.2 | 1.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.2 | 1.1 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.2 | 0.7 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.2 | 1.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.2 | 0.7 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
| 0.2 | 3.4 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.2 | 1.8 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.2 | 0.6 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903) |
| 0.1 | 0.7 | GO:0042979 | ornithine decarboxylase regulator activity(GO:0042979) |
| 0.1 | 0.6 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.1 | 1.1 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 1.1 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.1 | 1.8 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 0.4 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.1 | 2.5 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 1.0 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.1 | 0.7 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 0.4 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
| 0.1 | 1.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.1 | 1.1 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 2.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 3.6 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.1 | 0.5 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.1 | 4.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.1 | 0.6 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.1 | 3.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 0.3 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 1.5 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 0.3 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.1 | 0.3 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.1 | 0.9 | GO:0036122 | BMP binding(GO:0036122) |
| 0.1 | 3.8 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.1 | 0.3 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.1 | 1.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 1.1 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.6 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 3.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 1.5 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 8.8 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 2.5 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 1.1 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 0.7 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.6 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.7 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.1 | 1.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 2.0 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 1.0 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 4.6 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.3 | GO:0032896 | palmitoyl-CoA 9-desaturase activity(GO:0032896) |
| 0.1 | 0.2 | GO:1990955 | G-rich single-stranded DNA binding(GO:1990955) |
| 0.1 | 1.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.1 | 0.6 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 0.5 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 1.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 0.4 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 1.0 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 0.3 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 0.6 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.1 | 0.5 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 0.2 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.1 | 0.5 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.1 | 0.7 | GO:0048185 | activin binding(GO:0048185) |
| 0.1 | 1.5 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.1 | 0.6 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.1 | 1.0 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 2.2 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.1 | 0.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 2.9 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 0.2 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 1.1 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 0.6 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 2.8 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.2 | GO:0070891 | peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891) |
| 0.1 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 1.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 0.2 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.0 | 1.9 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.3 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.0 | 13.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.1 | GO:0031432 | titin binding(GO:0031432) |
| 0.0 | 0.4 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.0 | 0.3 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.0 | 0.2 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.0 | 0.6 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 0.6 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 0.0 | 0.5 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.5 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.9 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.1 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.0 | 3.7 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.0 | 0.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 0.3 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.1 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 1.0 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 1.3 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.1 | GO:0031720 | haptoglobin binding(GO:0031720) |
| 0.0 | 1.0 | GO:0016247 | channel regulator activity(GO:0016247) |
| 0.0 | 3.2 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.0 | 1.0 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 2.6 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.0 | 0.1 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
| 0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.1 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 1.2 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.4 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 1.2 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.2 | GO:0070290 | phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.0 | 0.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.0 | 0.2 | GO:0070728 | leucine binding(GO:0070728) |
| 0.0 | 0.1 | GO:0016748 | succinyltransferase activity(GO:0016748) |
| 0.0 | 0.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.2 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 2.4 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 0.6 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 1.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 10.8 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.7 | GO:0004407 | histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558) |
| 0.0 | 0.1 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.0 | 1.1 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 1.5 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.1 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.0 | 0.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.0 | 0.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 1.6 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.3 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.1 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.0 | 0.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.1 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.1 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.3 | 11.0 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.3 | 4.7 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.3 | 10.8 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.2 | 3.8 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.2 | 7.5 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.1 | 1.9 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 2.2 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 8.9 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.1 | 4.6 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 3.0 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 1.1 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.1 | 0.9 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.1 | 5.0 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.1 | 2.3 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 3.1 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.1 | 0.9 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.1 | 2.1 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 0.9 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.1 | 2.9 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 0.5 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.1 | 2.8 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
| 0.1 | 0.3 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 0.5 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.1 | 0.7 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 1.6 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 1.9 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 0.5 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
| 0.0 | 0.9 | PID_BCR_5PATHWAY | BCR signaling pathway |
| 0.0 | 1.4 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.6 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.8 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.8 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.2 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 0.9 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 1.0 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.4 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 1.3 | PID_NFAT_3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 1.2 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.1 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.6 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.0 | 0.7 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 0.4 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.4 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.0 | 0.3 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.1 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.4 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.1 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.2 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.2 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | Genes involved in Transmission across Chemical Synapses |
| 0.5 | 6.8 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.5 | 5.0 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.5 | 7.5 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.3 | 2.2 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.3 | 12.4 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 3.4 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.2 | 5.6 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.2 | 1.6 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
| 0.2 | 4.6 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.2 | 4.7 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.2 | 2.7 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.2 | 5.7 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.2 | 0.3 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.2 | 0.9 | REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.1 | 0.6 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.1 | 0.7 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 3.7 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
| 0.1 | 0.5 | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.1 | 1.7 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 1.5 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 1.6 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 2.9 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.1 | 1.5 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 3.1 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 1.1 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
| 0.1 | 1.9 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 1.3 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 1.6 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 3.2 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 1.0 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 1.0 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.1 | 6.6 | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | Genes involved in G alpha (q) signalling events |
| 0.1 | 2.2 | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.1 | 2.5 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 1.1 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 0.8 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.1 | 2.0 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.2 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.1 | 4.1 | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | Genes involved in Recruitment of mitotic centrosome proteins and complexes |
| 0.0 | 0.2 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.6 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.5 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.0 | 0.5 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 1.0 | REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.0 | 1.4 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 0.3 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.9 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 1.3 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.0 | 2.4 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 0.3 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 0.8 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 0.5 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.0 | 3.3 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 0.6 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.6 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.5 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.0 | 0.3 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.2 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.0 | 0.1 | REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 0.3 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.2 | REACTOME_REGULATION_OF_APOPTOSIS | Genes involved in Regulation of Apoptosis |
| 0.0 | 0.3 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.2 | REACTOME_DOWNSTREAM_TCR_SIGNALING | Genes involved in Downstream TCR signaling |
| 0.0 | 0.7 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.4 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.8 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
