Motif ID: Nanog

Z-value: 0.806


Transcription factors associated with Nanog:

Gene SymbolEntrez IDGene Name
Nanog ENSMUSG00000012396.6 Nanog

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nanogmm10_v2_chr6_+_122707489_1227076080.182.0e-01Click!


Activity profile for motif Nanog.

activity profile for motif Nanog


Sorted Z-values histogram for motif Nanog

Sorted Z-values for motif Nanog



Network of associatons between targets according to the STRING database.



First level regulatory network of Nanog

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_154960915 7.501 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr9_+_65890237 7.161 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr7_-_115846080 5.450 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr7_+_67647405 5.282 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr3_+_88081997 4.978 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr4_-_109665249 4.459 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr8_-_89044162 4.251 ENSMUST00000034090.6
Sall1
sal-like 1 (Drosophila)
chr8_-_61902669 4.084 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr10_-_42583628 3.988 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr15_-_71954395 3.887 ENSMUST00000159410.1
Col22a1
collagen, type XXII, alpha 1
chr2_+_20737306 3.862 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr15_+_25773985 3.754 ENSMUST00000125667.1
Myo10
myosin X
chr5_+_33658123 3.725 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr5_+_33658567 3.551 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chrX_-_60893430 3.491 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chrX_+_134308084 3.331 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr14_+_73237891 3.302 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr10_+_58394381 3.265 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr2_+_134786154 3.177 ENSMUST00000110116.1
Plcb1
phospholipase C, beta 1
chr1_-_52490736 3.053 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chrY_-_1245685 3.028 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr6_+_124829582 2.879 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr6_-_67037399 2.863 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr5_+_33658550 2.776 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr10_+_58394361 2.755 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr6_+_124829540 2.730 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chr18_-_78206408 2.688 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr10_-_7212222 2.653 ENSMUST00000015346.5
Cnksr3
Cnksr family member 3
chr4_-_58553553 2.636 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr7_+_79660196 2.608 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr7_+_112742025 2.522 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr17_+_78491549 2.452 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr19_-_9899450 2.441 ENSMUST00000025562.7
Incenp
inner centromere protein
chr18_+_57142782 2.386 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr13_+_23752267 2.359 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr13_-_89742244 2.157 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr17_-_25727364 2.088 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr6_+_71282280 2.053 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr14_-_12345847 2.049 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr9_-_52168111 2.013 ENSMUST00000165519.1
Zc3h12c
zinc finger CCCH type containing 12C
chr4_+_116708467 1.982 ENSMUST00000030452.6
Ccdc163
coiled-coil domain containing 163
chr2_+_62664279 1.968 ENSMUST00000028257.2
Gca
grancalcin
chr2_+_38511643 1.951 ENSMUST00000054234.3
ENSMUST00000112902.1
ENSMUST00000112895.1
Nek6


NIMA (never in mitosis gene a)-related expressed kinase 6


chr6_+_34746368 1.928 ENSMUST00000142716.1
Cald1
caldesmon 1
chr2_+_116067213 1.911 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chrX_-_53269786 1.904 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr10_+_26772477 1.879 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr13_-_89742490 1.859 ENSMUST00000109546.2
Vcan
versican
chr9_-_66514567 1.826 ENSMUST00000056890.8
Fbxl22
F-box and leucine-rich repeat protein 22
chr3_-_63851251 1.778 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr4_-_42661893 1.775 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr7_-_144939823 1.716 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr17_-_51826562 1.691 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr2_+_18064564 1.673 ENSMUST00000114671.1
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr8_-_25201349 1.662 ENSMUST00000084512.4
ENSMUST00000084030.4
Tacc1

transforming, acidic coiled-coil containing protein 1

chr11_-_40733373 1.660 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr9_+_109096659 1.582 ENSMUST00000130366.1
Plxnb1
plexin B1
chr11_+_44617310 1.539 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr13_-_47106176 1.516 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chr15_-_50889043 1.493 ENSMUST00000183997.1
ENSMUST00000183757.1
Trps1

trichorhinophalangeal syndrome I (human)

chrX_-_20962005 1.456 ENSMUST00000123836.1
Uxt
ubiquitously expressed transcript
chr12_-_34528844 1.434 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr18_+_77185815 1.417 ENSMUST00000079618.4
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr6_-_108185552 1.403 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr17_-_59013264 1.375 ENSMUST00000174122.1
ENSMUST00000025065.5
Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr7_+_82337218 1.360 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr11_-_101171302 1.313 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr9_-_44342332 1.304 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr5_-_16731074 1.262 ENSMUST00000073014.5
Gm8991
predicted pseudogene 8991
chrX_+_36795642 1.252 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr2_-_116067391 1.246 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr1_-_186117251 1.232 ENSMUST00000045388.7
Lyplal1
lysophospholipase-like 1
chr19_-_36736653 1.195 ENSMUST00000087321.2
Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr12_-_91384403 1.184 ENSMUST00000141429.1
Cep128
centrosomal protein 128
chr1_-_158814469 1.153 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr4_+_43058939 1.144 ENSMUST00000079978.6
Unc13b
unc-13 homolog B (C. elegans)
chr7_+_64287665 1.140 ENSMUST00000032736.4
Mtmr10
myotubularin related protein 10
chr3_-_39359128 1.111 ENSMUST00000056409.2
Gm9845
predicted pseudogene 9845
chr9_+_44379490 1.066 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr4_+_43059028 1.060 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
Unc13b


unc-13 homolog B (C. elegans)


chr13_-_19619820 1.059 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chr9_+_44379536 1.049 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr12_+_3891728 1.044 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr13_+_96082158 1.007 ENSMUST00000185178.1
Gm17190
predicted gene 17190
chr13_-_3893556 0.998 ENSMUST00000099946.4
Net1
neuroepithelial cell transforming gene 1
chr9_+_104063678 0.993 ENSMUST00000047799.5
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr12_-_83921809 0.993 ENSMUST00000135962.1
ENSMUST00000155112.1
ENSMUST00000136848.1
ENSMUST00000126943.1
Numb



numb gene homolog (Drosophila)



chr8_+_61487715 0.987 ENSMUST00000034058.6
ENSMUST00000126575.1
Cbr4

carbonyl reductase 4

chr7_+_59228743 0.985 ENSMUST00000107537.1
Ube3a
ubiquitin protein ligase E3A
chr9_-_15357692 0.967 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr13_-_21716143 0.957 ENSMUST00000091756.1
Hist1h2bl
histone cluster 1, H2bl
chrX_-_135009185 0.951 ENSMUST00000113185.2
ENSMUST00000064659.5
Zmat1

zinc finger, matrin type 1

chr6_+_38551334 0.951 ENSMUST00000163047.1
ENSMUST00000161538.1
ENSMUST00000057692.4
Luc7l2


LUC7-like 2 (S. cerevisiae)


chr12_+_72441933 0.949 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr13_+_24943144 0.945 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr15_+_34453285 0.933 ENSMUST00000060894.7
BC030476
cDNA sequence BC030476
chr6_+_80018877 0.916 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr12_-_111813834 0.908 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr3_+_54481429 0.902 ENSMUST00000091130.3
Gm5641
predicted gene 5641
chr15_-_51991679 0.902 ENSMUST00000022927.9
Rad21
RAD21 homolog (S. pombe)
chr6_+_80019008 0.897 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr6_-_23132981 0.895 ENSMUST00000031707.7
Aass
aminoadipate-semialdehyde synthase
chr3_+_103968110 0.892 ENSMUST00000117150.1
ENSMUST00000063717.7
ENSMUST00000055425.8
ENSMUST00000123611.1
ENSMUST00000090685.4
Phtf1




putative homeodomain transcription factor 1




chr15_-_103251465 0.882 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr13_-_41273977 0.874 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr7_+_25681158 0.868 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr12_-_83921899 0.849 ENSMUST00000117217.1
Numb
numb gene homolog (Drosophila)
chr4_+_128688726 0.848 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr17_-_32800938 0.846 ENSMUST00000080905.6
Zfp811
zinc finger protein 811
chr19_+_7557473 0.839 ENSMUST00000141887.1
ENSMUST00000136756.1
Pla2g16

phospholipase A2, group XVI

chr1_-_172027251 0.837 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr4_-_126968124 0.828 ENSMUST00000106108.2
Zmym4
zinc finger, MYM-type 4
chr13_-_85127514 0.813 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr2_+_29060239 0.784 ENSMUST00000100237.3
Ttf1
transcription termination factor, RNA polymerase I
chr10_-_99126321 0.784 ENSMUST00000060761.5
Phxr2
per-hexamer repeat gene 2
chr13_-_12258093 0.764 ENSMUST00000099856.4
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr9_-_7184440 0.755 ENSMUST00000140466.1
Dync2h1
dynein cytoplasmic 2 heavy chain 1
chr15_-_13173607 0.746 ENSMUST00000036439.4
Cdh6
cadherin 6
chr17_+_35379608 0.731 ENSMUST00000081435.4
H2-Q4
histocompatibility 2, Q region locus 4
chr3_+_89421619 0.723 ENSMUST00000094378.3
ENSMUST00000137793.1
Shc1

src homology 2 domain-containing transforming protein C1

chr19_+_60889749 0.714 ENSMUST00000003313.8
Grk5
G protein-coupled receptor kinase 5
chr2_+_144527718 0.713 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr16_+_13671922 0.704 ENSMUST00000035426.5
3110001I22Rik
RIKEN cDNA 3110001I22 gene
chr13_+_44729794 0.696 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr14_+_79515618 0.696 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr16_+_87454976 0.686 ENSMUST00000119504.1
ENSMUST00000131356.1
Usp16

ubiquitin specific peptidase 16

chr7_-_100467149 0.683 ENSMUST00000184420.1
RP23-308M1.2
RP23-308M1.2
chr12_+_72441852 0.646 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr11_-_102406783 0.636 ENSMUST00000155104.1
ENSMUST00000130436.1
Slc25a39

solute carrier family 25, member 39

chr2_+_115581667 0.634 ENSMUST00000166472.1
ENSMUST00000110918.2
BC052040

cDNA sequence BC052040

chr7_+_89404356 0.631 ENSMUST00000058755.3
Fzd4
frizzled homolog 4 (Drosophila)
chr9_+_108490676 0.627 ENSMUST00000178075.1
ENSMUST00000085044.7
ENSMUST00000166103.2
ENSMUST00000006854.7
Usp19



ubiquitin specific peptidase 19



chr10_+_77622363 0.603 ENSMUST00000172772.1
Ube2g2
ubiquitin-conjugating enzyme E2G 2
chr16_+_19760902 0.601 ENSMUST00000119468.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr7_-_6011010 0.593 ENSMUST00000086338.1
Vmn1r65
vomeronasal 1 receptor 65
chr6_-_39725448 0.590 ENSMUST00000002487.8
Braf
Braf transforming gene
chr6_-_8259098 0.588 ENSMUST00000012627.4
Rpa3
replication protein A3
chr4_+_129336012 0.588 ENSMUST00000119480.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr11_-_101095367 0.585 ENSMUST00000019447.8
Psmc3ip
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr19_+_7557452 0.572 ENSMUST00000025925.4
ENSMUST00000136465.1
Pla2g16

phospholipase A2, group XVI

chr5_+_63812447 0.570 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr12_-_101958148 0.569 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chr2_+_69897255 0.553 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr18_+_24205303 0.546 ENSMUST00000000430.7
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr14_-_26534870 0.544 ENSMUST00000139075.1
ENSMUST00000102956.1
Slmap

sarcolemma associated protein

chr4_-_149454971 0.532 ENSMUST00000030848.2
Rbp7
retinol binding protein 7, cellular
chr14_+_56887795 0.522 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr1_+_169969409 0.512 ENSMUST00000180638.1
3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr5_-_99978914 0.511 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
Hnrnpd




heterogeneous nuclear ribonucleoprotein D




chr1_+_174501796 0.504 ENSMUST00000030039.7
Fmn2
formin 2
chr1_-_60566708 0.498 ENSMUST00000027168.5
ENSMUST00000090293.4
ENSMUST00000140485.1
Raph1


Ras association (RalGDS/AF-6) and pleckstrin homology domains 1


chr11_-_23895208 0.498 ENSMUST00000102863.2
ENSMUST00000020513.3
Papolg

poly(A) polymerase gamma

chr6_+_38551786 0.495 ENSMUST00000161227.1
Luc7l2
LUC7-like 2 (S. cerevisiae)
chr10_+_18469958 0.494 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr7_-_130547358 0.479 ENSMUST00000160289.1
Nsmce4a
non-SMC element 4 homolog A (S. cerevisiae)
chr4_+_107968332 0.477 ENSMUST00000106713.3
Slc1a7
solute carrier family 1 (glutamate transporter), member 7
chr9_-_106891401 0.474 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr8_+_78509319 0.471 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr2_+_112379204 0.469 ENSMUST00000028552.3
Katnbl1
katanin p80 subunit B like 1
chr3_+_108653931 0.467 ENSMUST00000029483.8
ENSMUST00000124384.1
Clcc1

chloride channel CLIC-like 1

chr4_+_20008357 0.455 ENSMUST00000117632.1
ENSMUST00000098244.1
Ttpa

tocopherol (alpha) transfer protein

chr2_-_37703845 0.454 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr3_-_146499721 0.453 ENSMUST00000029839.4
Spata1
spermatogenesis associated 1
chr7_+_3629985 0.447 ENSMUST00000008517.6
ENSMUST00000179769.1
Prpf31

PRP31 pre-mRNA processing factor 31 homolog (yeast)

chr1_+_93512079 0.429 ENSMUST00000120301.1
ENSMUST00000041983.4
ENSMUST00000122402.1
Farp2


FERM, RhoGEF and pleckstrin domain protein 2


chr11_+_115154139 0.428 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr13_+_111686303 0.418 ENSMUST00000047412.4
ENSMUST00000109271.2
Mier3

mesoderm induction early response 1, family member 3

chr2_-_86347764 0.415 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr3_+_10088173 0.412 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chr10_+_75037066 0.406 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr11_+_86484647 0.398 ENSMUST00000020827.6
Rnft1
ring finger protein, transmembrane 1
chr18_+_34736359 0.390 ENSMUST00000105038.2
Gm3550
predicted gene 3550
chr7_+_103550368 0.380 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr11_+_95712673 0.366 ENSMUST00000107717.1
Zfp652
zinc finger protein 652
chr3_+_88965812 0.362 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr8_-_120589304 0.357 ENSMUST00000034278.5
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr13_-_104178399 0.344 ENSMUST00000179891.1
ENSMUST00000022224.9
ENSMUST00000141557.1
ENSMUST00000144060.1
ENSMUST00000091264.1
Trappc13



Trappc13
trafficking protein particle complex 13



trafficking protein particle complex 13
chr5_-_103977360 0.341 ENSMUST00000048118.8
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr3_+_114030532 0.338 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1

collagen, type XI, alpha 1

chr8_-_36732897 0.334 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr3_+_37312514 0.328 ENSMUST00000057975.7
ENSMUST00000108121.3
Bbs12

Bardet-Biedl syndrome 12 (human)

chr2_+_32363680 0.321 ENSMUST00000113331.1
ENSMUST00000113338.2
Ciz1

CDKN1A interacting zinc finger protein 1

chr10_+_33905015 0.319 ENSMUST00000169670.1
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr7_-_141655319 0.317 ENSMUST00000062451.7
Muc6
mucin 6, gastric
chr9_+_113930934 0.317 ENSMUST00000084885.5
ENSMUST00000009885.7
Ubp1

upstream binding protein 1

chr3_-_37312418 0.316 ENSMUST00000075537.6
ENSMUST00000071400.6
ENSMUST00000102955.4
ENSMUST00000140956.1
Cetn4



centrin 4



chr2_+_69897220 0.315 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chrX_-_153037549 0.307 ENSMUST00000051484.3
Mageh1
melanoma antigen, family H, 1
chr19_-_53464721 0.293 ENSMUST00000180489.1
5830416P10Rik
RIKEN cDNA 5830416P10 gene
chr1_+_135584773 0.292 ENSMUST00000067468.4
Gm4793
predicted gene 4793
chr9_+_92309362 0.286 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr16_+_13671980 0.285 ENSMUST00000069281.7
Bfar
bifunctional apoptosis regulator
chr7_-_90475971 0.283 ENSMUST00000032843.7
Tmem126b
transmembrane protein 126B
chr12_-_56345862 0.279 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr7_+_119561699 0.277 ENSMUST00000167935.2
ENSMUST00000130583.1
Acsm2

acyl-CoA synthetase medium-chain family member 2

chr17_+_35439155 0.275 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr3_+_79884496 0.270 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr17_-_43543639 0.267 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr19_+_6046576 0.265 ENSMUST00000138532.1
ENSMUST00000129081.1
ENSMUST00000156550.1
Syvn1


synovial apoptosis inhibitor 1, synoviolin


chr19_-_56822161 0.263 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
1.4 4.3 GO:0072092 ureteric bud invasion(GO:0072092)
1.2 6.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
1.1 3.2 GO:0070671 monocyte extravasation(GO:0035696) activation of meiosis involved in egg activation(GO:0060466) response to interleukin-12(GO:0070671) positive regulation of acrosome reaction(GO:2000344) regulation of monocyte extravasation(GO:2000437)
0.9 2.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.8 4.0 GO:0021764 amygdala development(GO:0021764)
0.8 5.4 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.7 6.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.7 2.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.6 11.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.6 1.8 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.6 2.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.4 2.4 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.4 1.6 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.4 3.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 2.9 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.3 1.4 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 2.0 GO:1904936 forebrain anterior/posterior pattern specification(GO:0021797) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.3 0.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507)
0.3 1.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.3 0.9 GO:0006553 lysine metabolic process(GO:0006553)
0.3 0.8 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 0.5 GO:1901355 response to rapamycin(GO:1901355)
0.2 1.0 GO:0030647 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.2 0.5 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.2 2.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 2.5 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.2 4.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 2.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.2 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.2 3.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 1.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2 0.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.2 0.7 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.2 0.5 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.2 1.0 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 1.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.2 0.5 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.2 4.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 3.5 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.7 GO:1990839 response to endothelin(GO:1990839)
0.1 0.8 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 1.0 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.9 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 2.7 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.3 GO:0035989 tendon development(GO:0035989)
0.1 1.0 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.3 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 1.1 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.1 1.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.9 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) t-circle formation(GO:0090656)
0.1 1.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 0.1 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.1 0.9 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 1.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 2.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 2.4 GO:0034508 centromere complex assembly(GO:0034508)
0.1 0.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 3.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.1 4.0 GO:0008347 glial cell migration(GO:0008347)
0.1 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 1.0 GO:0051451 myoblast migration(GO:0051451)
0.1 1.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.6 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 0.3 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1 3.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.1 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.1 2.0 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 0.4 GO:0061038 negative regulation of acute inflammatory response(GO:0002674) uterus morphogenesis(GO:0061038)
0.1 0.8 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.3 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.6 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:0019401 alditol biosynthetic process(GO:0019401)
0.0 0.4 GO:0033623 neuron remodeling(GO:0016322) regulation of integrin activation(GO:0033623)
0.0 0.0 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.0 1.0 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 2.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 2.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.4 GO:0033692 cellular polysaccharide biosynthetic process(GO:0033692)
0.0 1.2 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 2.4 GO:0000910 cytokinesis(GO:0000910)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.5 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.9 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.2 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0000801 central element(GO:0000801)
0.6 2.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.4 2.2 GO:0044305 calyx of Held(GO:0044305)
0.2 2.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.9 GO:0030478 actin cap(GO:0030478)
0.2 0.8 GO:0060187 cell pole(GO:0060187)
0.2 1.3 GO:0071817 MMXD complex(GO:0071817)
0.2 4.3 GO:0010369 chromocenter(GO:0010369)
0.2 0.9 GO:0000798 nuclear cohesin complex(GO:0000798)
0.2 2.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.2 GO:0042587 glycogen granule(GO:0042587)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 4.1 GO:0002102 podosome(GO:0002102)
0.1 2.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 2.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 3.8 GO:0016459 myosin complex(GO:0016459)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 1.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 5.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 4.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 2.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.4 GO:0000776 kinetochore(GO:0000776)
0.0 7.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 10.3 GO:0005813 centrosome(GO:0005813)
0.0 1.3 GO:0000793 condensed chromosome(GO:0000793)
0.0 6.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 5.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0032027 myosin light chain binding(GO:0032027)
0.8 5.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.7 2.2 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.5 1.4 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.4 2.7 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.4 3.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 1.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.3 2.4 GO:0001849 complement component C1q binding(GO:0001849)
0.3 5.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.3 4.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 4.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 1.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.6 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 2.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 1.3 GO:0043176 amine binding(GO:0043176)
0.2 0.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 0.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 3.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 0.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 2.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 4.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 5.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 1.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.9 GO:0004630 phospholipase D activity(GO:0004630)
0.1 1.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.5 GO:0019841 retinol binding(GO:0019841)
0.1 15.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.5 GO:0089720 caspase binding(GO:0089720)
0.1 1.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.0 GO:0048038 quinone binding(GO:0048038)
0.1 3.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 2.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 3.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.9 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 3.0 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.7 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 4.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.3 GO:0004519 endonuclease activity(GO:0004519)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 14.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 7.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 3.2 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 4.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 3.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 12.3 PID_CDC42_PATHWAY CDC42 signaling events
0.1 4.2 NABA_COLLAGENS Genes encoding collagen proteins
0.1 0.7 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 5.9 PID_E2F_PATHWAY E2F transcription factor network
0.1 2.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.9 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.2 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.4 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 1.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.9 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 2.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 3.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.3 4.0 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 1.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 6.0 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 0.9 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 5.1 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 2.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 8.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.4 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 4.2 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 2.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.6 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 0.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 4.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.2 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.6 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK