Motif ID: Neurod1

Z-value: 1.013


Transcription factors associated with Neurod1:

Gene SymbolEntrez IDGene Name
Neurod1 ENSMUSG00000034701.9 Neurod1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Neurod1mm10_v2_chr2_-_79456750_794567610.624.5e-07Click!


Activity profile for motif Neurod1.

activity profile for motif Neurod1


Sorted Z-values histogram for motif Neurod1

Sorted Z-values for motif Neurod1



Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_42907563 6.834 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr10_+_69706326 5.008 ENSMUST00000182992.1
 Ank3
ankyrin 3, epithelial
chr11_-_107915041 4.378 ENSMUST00000039071.2
 Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr5_-_28210022 4.344 ENSMUST00000118882.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr12_-_34528844 3.585 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chr13_-_97747399 3.529 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_155232710 3.377 ENSMUST00000035914.3
 BC034090
cDNA sequence BC034090
chr2_-_84775388 3.241 ENSMUST00000023994.3
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84775420 3.121 ENSMUST00000111641.1
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr9_+_46998931 2.924 ENSMUST00000178065.1
 Gm4791
predicted gene 4791
chr6_+_56017489 2.854 ENSMUST00000052827.4
 Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr17_-_6449571 2.669 ENSMUST00000180035.1
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr7_+_122289297 2.643 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr15_-_78773452 2.432 ENSMUST00000018313.5
 Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_6730051 2.383 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr7_+_121707189 2.293 ENSMUST00000065310.2
 1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr4_-_20778527 2.287 ENSMUST00000119374.1
 Nkain3
Na+/K+ transporting ATPase interacting 3
chr4_-_22488296 2.228 ENSMUST00000178174.1
 Pou3f2
POU domain, class 3, transcription factor 2
chr6_+_54681687 2.200 ENSMUST00000046276.6
 2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr3_-_84259812 2.187 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 138 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
2.1 6.4 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.5 5.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 4.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 4.2 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.4 3.6 GO:0030035 microspike assembly(GO:0030035)
0.6 3.4 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 3.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 3.3 GO:0051291 protein heterooligomerization(GO:0051291)
0.2 2.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.2 2.9 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 2.9 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.2 2.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 2.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5 2.6 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.4 2.4 GO:0003383 apical constriction(GO:0003383)
0.3 2.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 2.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 2.2 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 2.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 5.7 GO:0072562 blood microparticle(GO:0072562)
0.2 5.0 GO:0033270 paranode region of axon(GO:0033270)
0.1 4.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 4.2 GO:0001726 ruffle(GO:0001726)
0.2 3.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 3.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 3.1 GO:0030175 filopodium(GO:0030175)
0.0 2.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 2.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.6 GO:0031526 brush border membrane(GO:0031526)
0.0 2.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.7 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.7 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 6.4 GO:0001848 complement binding(GO:0001848)
0.2 6.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 5.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 4.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 4.1 GO:0030507 spectrin binding(GO:0030507)
0.3 3.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 2.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.7 GO:0005080 protein kinase C binding(GO:0005080)
0.4 2.6 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 2.6 GO:0035497 cAMP response element binding(GO:0035497)
0.8 2.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 2.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 2.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 2.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 2.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.0 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.6 ST_GA13_PATHWAY G alpha 13 Pathway
0.0 4.1 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.2 3.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 2.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.0 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 2.0 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.7 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.3 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.7 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 6.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 4.6 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 3.4 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.6 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.9 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.8 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 1.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.5 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.5 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.2 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling