Motif ID: Nfe2l2

Z-value: 0.486


Transcription factors associated with Nfe2l2:

Gene SymbolEntrez IDGene Name
Nfe2l2 ENSMUSG00000015839.6 Nfe2l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfe2l2mm10_v2_chr2_-_75704535_757046410.221.1e-01Click!


Activity profile for motif Nfe2l2.

activity profile for motif Nfe2l2


Sorted Z-values histogram for motif Nfe2l2

Sorted Z-values for motif Nfe2l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_172219715 2.370 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr4_+_116685859 1.666 ENSMUST00000129315.1
ENSMUST00000106470.1
Prdx1

peroxiredoxin 1

chr4_+_116685544 1.570 ENSMUST00000135573.1
ENSMUST00000151129.1
Prdx1

peroxiredoxin 1

chrX_-_52613913 1.453 ENSMUST00000069360.7
Gpc3
glypican 3
chr5_+_128601106 1.425 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chr18_-_53418004 1.399 ENSMUST00000025419.7
Ppic
peptidylprolyl isomerase C
chr17_+_86963279 1.270 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr7_-_44997535 1.234 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chr1_+_165769392 1.226 ENSMUST00000040298.4
Creg1
cellular repressor of E1A-stimulated genes 1
chrX_-_52613936 1.222 ENSMUST00000114857.1
Gpc3
glypican 3
chr7_-_126799134 1.218 ENSMUST00000087566.4
Aldoa
aldolase A, fructose-bisphosphate
chr7_-_126799163 1.177 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr17_-_25570678 1.107 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr14_+_62292475 1.052 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr3_+_131110350 1.001 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr18_+_61639542 0.994 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr11_-_109473598 0.977 ENSMUST00000070152.5
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr4_-_126321669 0.970 ENSMUST00000102617.4
Adprhl2
ADP-ribosylhydrolase like 2
chr7_-_44997221 0.947 ENSMUST00000152341.1
Bcl2l12
BCL2-like 12 (proline rich)
chr3_+_28805436 0.934 ENSMUST00000043867.5
Rpl22l1
ribosomal protein L22 like 1
chr17_-_47834682 0.930 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr7_-_105482197 0.929 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr17_-_25868727 0.926 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr2_+_180171485 0.910 ENSMUST00000061437.4
Adrm1
adhesion regulating molecule 1
chr14_-_20393473 0.908 ENSMUST00000061444.3
Mrps16
mitochondrial ribosomal protein S16
chr3_+_137623672 0.904 ENSMUST00000053855.7
Ddit4l
DNA-damage-inducible transcript 4-like
chr7_-_102250086 0.896 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr16_+_90220742 0.845 ENSMUST00000023707.9
Sod1
superoxide dismutase 1, soluble
chr19_-_4037910 0.839 ENSMUST00000169613.1
Gstp1
glutathione S-transferase, pi 1
chr1_+_136017967 0.788 ENSMUST00000063719.8
ENSMUST00000118832.1
Tmem9

transmembrane protein 9

chr2_+_112261926 0.785 ENSMUST00000028553.3
Nop10
NOP10 ribonucleoprotein
chr2_-_25272380 0.744 ENSMUST00000028342.6
Ssna1
Sjogren's syndrome nuclear autoantigen 1
chr1_+_136018062 0.742 ENSMUST00000117950.1
Tmem9
transmembrane protein 9
chr3_+_133338936 0.739 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr10_+_17796256 0.733 ENSMUST00000037964.6
Txlnb
taxilin beta
chr3_-_141982224 0.703 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr16_-_18811972 0.641 ENSMUST00000000028.7
ENSMUST00000115585.1
Cdc45

cell division cycle 45

chr19_+_23675839 0.640 ENSMUST00000056396.5
Gm6563
predicted pseudogene 6563
chr12_-_85288419 0.638 ENSMUST00000121930.1
Acyp1
acylphosphatase 1, erythrocyte (common) type
chr8_+_33653238 0.623 ENSMUST00000033992.8
Gsr
glutathione reductase
chr17_-_70998010 0.610 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr5_+_137758133 0.605 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr4_-_57956283 0.591 ENSMUST00000030051.5
Txn1
thioredoxin 1
chr5_-_53707532 0.581 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr1_-_155146755 0.554 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr12_+_55398775 0.543 ENSMUST00000021412.8
Psma6
proteasome (prosome, macropain) subunit, alpha type 6
chr10_-_34418465 0.541 ENSMUST00000099973.3
ENSMUST00000105512.1
ENSMUST00000047885.7
Nt5dc1


5'-nucleotidase domain containing 1


chr9_+_65214690 0.540 ENSMUST00000069000.7
Parp16
poly (ADP-ribose) polymerase family, member 16
chr16_+_20548577 0.515 ENSMUST00000003319.5
Abcf3
ATP-binding cassette, sub-family F (GCN20), member 3
chr7_+_28881656 0.509 ENSMUST00000066880.4
Capn12
calpain 12
chr5_+_100798627 0.507 ENSMUST00000016977.8
ENSMUST00000112898.1
ENSMUST00000112901.1
Mrps18c


mitochondrial ribosomal protein S18C


chr2_+_91054054 0.503 ENSMUST00000002171.7
ENSMUST00000111441.3
Psmc3

proteasome (prosome, macropain) 26S subunit, ATPase 3

chr18_+_61045139 0.500 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr14_+_26514554 0.492 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr17_-_24644933 0.491 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr2_+_91054009 0.470 ENSMUST00000067663.7
Psmc3
proteasome (prosome, macropain) 26S subunit, ATPase 3
chr11_+_78178651 0.464 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chrX_+_159372175 0.454 ENSMUST00000087143.6
Eif1ax
eukaryotic translation initiation factor 1A, X-linked
chr14_-_54617993 0.443 ENSMUST00000022803.4
Psmb5
proteasome (prosome, macropain) subunit, beta type 5
chr3_+_108256926 0.434 ENSMUST00000090569.5
Psma5
proteasome (prosome, macropain) subunit, alpha type 5
chr13_+_14613242 0.431 ENSMUST00000170836.2
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr7_+_44468020 0.424 ENSMUST00000117324.1
ENSMUST00000120852.1
ENSMUST00000118628.1
Josd2


Josephin domain containing 2


chr9_-_58313189 0.422 ENSMUST00000061799.8
Loxl1
lysyl oxidase-like 1
chr7_-_114276107 0.418 ENSMUST00000033008.9
Psma1
proteasome (prosome, macropain) subunit, alpha type 1
chr6_-_8259098 0.412 ENSMUST00000012627.4
Rpa3
replication protein A3
chr11_+_78178105 0.407 ENSMUST00000147819.1
Tlcd1
TLC domain containing 1
chr5_+_30013141 0.403 ENSMUST00000026845.7
Il6
interleukin 6
chr8_-_107588392 0.391 ENSMUST00000044106.4
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr19_-_4042165 0.389 ENSMUST00000042700.9
Gstp2
glutathione S-transferase, pi 2
chr7_-_29180699 0.385 ENSMUST00000059642.10
Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr8_+_105326354 0.383 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chr9_+_66126611 0.382 ENSMUST00000034945.5
Fam96a
family with sequence similarity 96, member A
chr5_-_100500592 0.381 ENSMUST00000149714.1
ENSMUST00000046154.5
Lin54

lin-54 homolog (C. elegans)

chr13_+_113342548 0.377 ENSMUST00000078163.7
BC067074
cDNA sequence BC067074
chr12_+_17544873 0.370 ENSMUST00000171737.1
Odc1
ornithine decarboxylase, structural 1
chr11_+_120673018 0.367 ENSMUST00000106158.2
ENSMUST00000103016.1
ENSMUST00000168714.1
Aspscr1


alveolar soft part sarcoma chromosome region, candidate 1 (human)


chr17_+_78491549 0.365 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr2_-_181691771 0.363 ENSMUST00000108778.1
ENSMUST00000165416.1
Rgs19

regulator of G-protein signaling 19

chr2_+_153649442 0.361 ENSMUST00000072997.3
ENSMUST00000109773.1
ENSMUST00000109774.2
ENSMUST00000081628.6
ENSMUST00000103151.1
ENSMUST00000088976.5
ENSMUST00000109772.1
ENSMUST00000103150.3
ENSMUST00000056495.7
Dnmt3b








DNA methyltransferase 3B








chr7_-_29180454 0.357 ENSMUST00000182328.1
Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr7_+_44468051 0.354 ENSMUST00000118493.1
Josd2
Josephin domain containing 2
chr5_+_66676098 0.352 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr12_+_80518990 0.346 ENSMUST00000021558.6
Galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr11_+_60537978 0.337 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr7_+_45639964 0.337 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr17_+_34032348 0.336 ENSMUST00000173354.1
ENSMUST00000116612.2
Rxrb

retinoid X receptor beta

chr19_+_8929628 0.329 ENSMUST00000096241.4
Eml3
echinoderm microtubule associated protein like 3
chr2_-_130397525 0.328 ENSMUST00000028897.7
Cpxm1
carboxypeptidase X 1 (M14 family)
chrX_-_167209149 0.324 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr11_-_74723829 0.320 ENSMUST00000102520.2
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr18_-_34954302 0.316 ENSMUST00000025217.8
Hspa9
heat shock protein 9
chr17_-_45573253 0.314 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr8_+_106510853 0.301 ENSMUST00000080797.6
Cdh3
cadherin 3
chr4_+_117251951 0.300 ENSMUST00000062824.5
Tmem53
transmembrane protein 53
chr10_+_128058947 0.294 ENSMUST00000052798.7
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr10_+_128058974 0.293 ENSMUST00000084771.2
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr2_+_25395866 0.289 ENSMUST00000028328.2
Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr11_-_98438941 0.289 ENSMUST00000002655.7
Mien1
migration and invasion enhancer 1
chrX_-_38252398 0.289 ENSMUST00000089056.3
ENSMUST00000089054.4
ENSMUST00000066498.7
Tmem255a


transmembrane protein 255A


chr7_-_104315455 0.288 ENSMUST00000106837.1
ENSMUST00000106839.2
ENSMUST00000070943.6
Trim12a


tripartite motif-containing 12A


chr6_-_129533267 0.288 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr11_-_50325599 0.287 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr2_+_120609383 0.274 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr12_-_40248073 0.272 ENSMUST00000169926.1
Ifrd1
interferon-related developmental regulator 1
chr9_-_116175318 0.266 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr4_+_130047840 0.264 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr6_+_17463927 0.255 ENSMUST00000115442.1
Met
met proto-oncogene
chr11_+_107479549 0.251 ENSMUST00000106750.4
Psmd12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr11_+_107479478 0.251 ENSMUST00000021063.6
ENSMUST00000106752.3
Psmd12

proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

chr19_-_4839286 0.248 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr9_+_107578887 0.248 ENSMUST00000149638.1
ENSMUST00000139274.1
ENSMUST00000130053.1
ENSMUST00000122985.1
ENSMUST00000127380.1
ENSMUST00000139581.1
Nat6





N-acetyltransferase 6





chr11_-_30649510 0.245 ENSMUST00000074613.3
Acyp2
acylphosphatase 2, muscle type
chr7_+_19083842 0.244 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
Dmpk



dystrophia myotonica-protein kinase



chr5_-_45450221 0.243 ENSMUST00000015950.5
Qdpr
quinoid dihydropteridine reductase
chr4_+_117252010 0.239 ENSMUST00000125943.1
ENSMUST00000106434.1
Tmem53

transmembrane protein 53

chr12_+_70974621 0.238 ENSMUST00000160027.1
ENSMUST00000160864.1
Psma3

proteasome (prosome, macropain) subunit, alpha type 3

chr19_-_8929323 0.232 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr17_-_26939464 0.227 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr5_+_31697960 0.226 ENSMUST00000114515.2
Bre
brain and reproductive organ-expressed protein
chr7_-_104353328 0.224 ENSMUST00000130139.1
ENSMUST00000059037.8
Trim12c

tripartite motif-containing 12C

chr4_-_140774196 0.221 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chr11_+_120673359 0.220 ENSMUST00000135346.1
ENSMUST00000127269.1
ENSMUST00000131727.2
ENSMUST00000149389.1
ENSMUST00000153346.1
Aspscr1




alveolar soft part sarcoma chromosome region, candidate 1 (human)




chr1_-_120074023 0.220 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr7_+_44848991 0.219 ENSMUST00000107885.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr7_+_141468776 0.219 ENSMUST00000058746.5
Cd151
CD151 antigen
chr16_+_20651652 0.218 ENSMUST00000007212.8
Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr14_-_18239053 0.216 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr5_+_138187485 0.211 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr18_+_73863672 0.210 ENSMUST00000134847.1
Mro
maestro
chr3_-_116968969 0.209 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr10_+_18845071 0.208 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr5_-_69592274 0.207 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
Gnpda2


glucosamine-6-phosphate deaminase 2


chr18_+_35598607 0.198 ENSMUST00000041314.8
ENSMUST00000115737.1
ENSMUST00000115736.1
ENSMUST00000115735.1
Paip2



polyadenylate-binding protein-interacting protein 2



chr16_+_58727910 0.195 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chr5_+_31698050 0.192 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
Bre



brain and reproductive organ-expressed protein



chr17_+_55952623 0.188 ENSMUST00000003274.6
Ebi3
Epstein-Barr virus induced gene 3
chr15_+_80255184 0.183 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr7_+_127800844 0.182 ENSMUST00000106271.1
ENSMUST00000138432.1
Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr3_-_116968827 0.173 ENSMUST00000119557.1
Palmd
palmdelphin
chr2_+_25272475 0.169 ENSMUST00000028341.4
Anapc2
anaphase promoting complex subunit 2
chr15_-_79834224 0.164 ENSMUST00000109623.1
ENSMUST00000109625.1
ENSMUST00000023060.6
ENSMUST00000089299.5
Cbx6

Npcd

chromobox 6

neuronal pentraxin chromo domain

chr8_+_69822429 0.155 ENSMUST00000164890.1
ENSMUST00000034325.4
Lpar2

lysophosphatidic acid receptor 2

chr3_-_89402650 0.154 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep

lens epithelial protein

chr16_-_17531019 0.151 ENSMUST00000142666.1
ENSMUST00000100125.3
Thap7

THAP domain containing 7

chr2_-_163419508 0.146 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chr2_-_26910569 0.135 ENSMUST00000015920.5
ENSMUST00000139815.1
ENSMUST00000102899.3
Med22


mediator complex subunit 22


chr4_+_136357423 0.134 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr19_+_8839298 0.127 ENSMUST00000160556.1
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr7_+_127800604 0.125 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr9_+_86695542 0.122 ENSMUST00000150367.2
A330041J22Rik
RIKEN cDNA A330041J22 gene
chrX_+_164269371 0.121 ENSMUST00000145412.1
ENSMUST00000033749.7
Pir

pirin

chr15_-_79605084 0.119 ENSMUST00000023065.6
Dmc1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
chr4_+_41569775 0.111 ENSMUST00000102963.3
Dnaic1
dynein, axonemal, intermediate chain 1
chr5_-_45450143 0.100 ENSMUST00000154962.1
Qdpr
quinoid dihydropteridine reductase
chr2_+_152105722 0.083 ENSMUST00000099225.2
Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr7_+_139834148 0.082 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr5_-_108675569 0.080 ENSMUST00000051757.7
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr3_+_122245625 0.080 ENSMUST00000178826.1
Gclm
glutamate-cysteine ligase, modifier subunit
chr7_-_44849075 0.077 ENSMUST00000047085.8
Tbc1d17
TBC1 domain family, member 17
chr1_-_167285110 0.072 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr2_-_120609319 0.071 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr14_+_30825580 0.070 ENSMUST00000006701.5
Tmem110
transmembrane protein 110
chr19_-_6080311 0.069 ENSMUST00000159832.1
Vps51
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr8_+_94984399 0.068 ENSMUST00000093271.6
Gpr56
G protein-coupled receptor 56
chr2_-_80581380 0.063 ENSMUST00000111760.2
Nckap1
NCK-associated protein 1
chr2_-_120609283 0.062 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr7_-_17056669 0.058 ENSMUST00000037762.4
Hif3a
hypoxia inducible factor 3, alpha subunit
chr7_+_127912510 0.051 ENSMUST00000033070.7
Kat8
K(lysine) acetyltransferase 8
chr15_-_79834261 0.048 ENSMUST00000148358.1
Cbx6
chromobox 6
chr5_-_21785115 0.033 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr5_-_45450121 0.032 ENSMUST00000127562.1
Qdpr
quinoid dihydropteridine reductase
chrX_+_71050160 0.032 ENSMUST00000082088.3
ENSMUST00000114629.3
Mamld1

mastermind-like domain containing 1

chr4_+_118961578 0.032 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr10_+_60277627 0.021 ENSMUST00000105465.1
ENSMUST00000177779.1
ENSMUST00000179238.1
ENSMUST00000004316.8
Psap



prosaposin



chr18_-_43477764 0.017 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr14_-_37135310 0.001 ENSMUST00000165649.2
Ghitm
growth hormone inducible transmembrane protein
chr4_-_133874682 0.000 ENSMUST00000168974.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.8 2.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 1.1 GO:0072034 renal vesicle induction(GO:0072034)
0.3 1.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.3 0.8 GO:0070488 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) neutrophil aggregation(GO:0070488)
0.2 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 2.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 2.2 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.2 0.6 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 5.1 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.2 0.6 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.2 0.7 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 1.4 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 0.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 0.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.2 0.8 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 0.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.4 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 0.4 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.1 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.3 GO:0051794 regulation of catagen(GO:0051794)
0.1 0.6 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.9 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 1.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 1.3 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.3 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.6 GO:0032620 interleukin-17 production(GO:0032620)
0.0 0.2 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 1.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0008078 zygotic determination of anterior/posterior axis, embryo(GO:0007354) mesodermal cell migration(GO:0008078)
0.0 0.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0014802 terminal cisterna(GO:0014802)
0.4 1.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.2 0.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 2.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 0.8 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 2.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 1.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 2.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 3.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 2.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 0.3 GO:0000235 astral microtubule(GO:0000235)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.2 GO:1990462 omegasome(GO:1990462)
0.0 1.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 3.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 1.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 0.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.2 1.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 1.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 1.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 2.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 2.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 1.0 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 1.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 2.2 GO:0002039 p53 binding(GO:0002039)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.0 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 1.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 1.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 2.4 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 2.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.6 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.0 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 5.3 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 2.4 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 0.4 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 1.2 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.4 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events