Motif ID: Nkx3-2

Z-value: 0.563


Transcription factors associated with Nkx3-2:

Gene SymbolEntrez IDGene Name
Nkx3-2 ENSMUSG00000049691.7 Nkx3-2



Activity profile for motif Nkx3-2.

activity profile for motif Nkx3-2


Sorted Z-values histogram for motif Nkx3-2

Sorted Z-values for motif Nkx3-2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx3-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66969616 4.458 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr2_-_104409992 4.090 ENSMUST00000149466.1
ENSMUST00000139015.1
D430041D05Rik

RIKEN cDNA D430041D05 gene

chr16_+_41532851 3.745 ENSMUST00000078873.4
Lsamp
limbic system-associated membrane protein
chr3_-_80802789 3.213 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr5_-_139130159 3.099 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr3_-_82074639 3.010 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr9_-_21037775 2.867 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr4_+_102421518 2.847 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_-_136171722 2.807 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr9_+_57940104 2.734 ENSMUST00000043059.7
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr11_+_3332426 2.258 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr3_+_123267445 2.233 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr10_+_38965515 2.223 ENSMUST00000019992.5
Lama4
laminin, alpha 4
chr14_+_80000292 2.054 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr2_-_156992021 2.010 ENSMUST00000109558.1
ENSMUST00000069600.6
ENSMUST00000072298.6
Ndrg3


N-myc downstream regulated gene 3


chr6_-_138421379 1.963 ENSMUST00000163065.1
Lmo3
LIM domain only 3
chr10_-_86732409 1.936 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr4_-_120747248 1.906 ENSMUST00000030376.7
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr11_+_43474276 1.725 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2

C1q and tumor necrosis factor related protein 2

chr17_+_70561739 1.712 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr15_-_102625061 1.576 ENSMUST00000184077.1
ENSMUST00000184906.1
ENSMUST00000169033.1
ATF7


Cyclic AMP-dependent transcription factor ATF-7


chr18_+_23752333 1.528 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
Mapre2


microtubule-associated protein, RP/EB family, member 2


chr3_+_86070915 1.484 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr9_+_112234257 1.432 ENSMUST00000149308.3
ENSMUST00000144424.2
ENSMUST00000139552.2
2900079G21Rik


RIKEN cDNA 2900079G21 gene


chr15_-_102624922 1.432 ENSMUST00000183765.1
ATF7
Cyclic AMP-dependent transcription factor ATF-7
chr15_-_45114926 1.425 ENSMUST00000022967.5
Kcnv1
potassium channel, subfamily V, member 1
chr6_+_96115249 1.418 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr15_-_37458523 1.397 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr7_-_4844665 1.350 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr12_-_72408934 1.341 ENSMUST00000078505.7
Rtn1
reticulon 1
chr7_+_6415164 1.339 ENSMUST00000160218.1
Smim17
small integral membrane protein 17
chr11_-_72489904 1.323 ENSMUST00000045303.3
Spns2
spinster homolog 2
chr15_-_100584075 1.286 ENSMUST00000184908.1
POU6F1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chr2_-_102400863 1.282 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr17_-_45686899 1.265 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr18_+_37447641 1.248 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr4_-_129121699 1.247 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr2_+_25054396 1.240 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
Nsmf




NMDA receptor synaptonuclear signaling and neuronal migration factor




chr2_-_58567157 1.226 ENSMUST00000056376.5
Acvr1
activin A receptor, type 1
chr9_+_40269430 1.199 ENSMUST00000171835.2
Scn3b
sodium channel, voltage-gated, type III, beta
chr6_+_86195214 1.199 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr7_+_5057161 1.195 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr13_-_92483996 1.126 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B
chrX_-_136203637 1.093 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
Tceal5


transcription elongation factor A (SII)-like 5


chr2_+_3713478 1.090 ENSMUST00000115053.2
Fam107b
family with sequence similarity 107, member B
chr8_+_104101625 1.078 ENSMUST00000034339.8
Cdh5
cadherin 5
chr4_-_40239779 1.073 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr3_-_37419566 1.071 ENSMUST00000138949.1
ENSMUST00000149449.1
ENSMUST00000108117.2
ENSMUST00000108118.2
ENSMUST00000099130.2
ENSMUST00000052645.6
Nudt6





nudix (nucleoside diphosphate linked moiety X)-type motif 6





chr11_+_85353156 1.049 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
Bcas3





breast carcinoma amplified sequence 3





chr13_-_30974023 1.041 ENSMUST00000021785.6
Exoc2
exocyst complex component 2
chr9_+_106448629 1.031 ENSMUST00000048527.7
Abhd14b
abhydrolase domain containing 14b
chr2_-_130424242 1.026 ENSMUST00000089581.4
Pced1a
PC-esterase domain containing 1A
chr11_-_98587193 1.018 ENSMUST00000052919.7
Ormdl3
ORM1-like 3 (S. cerevisiae)
chr2_+_25054355 0.988 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
Nsmf



NMDA receptor synaptonuclear signaling and neuronal migration factor



chr11_+_35121126 0.979 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr7_+_30169861 0.969 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr14_-_88471396 0.961 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr8_+_75213944 0.958 ENSMUST00000139848.1
Rasd2
RASD family, member 2
chr7_+_18987518 0.952 ENSMUST00000063563.7
Nanos2
nanos homolog 2 (Drosophila)
chr8_-_122551316 0.951 ENSMUST00000067252.7
Piezo1
piezo-type mechanosensitive ion channel component 1
chr19_+_46003468 0.948 ENSMUST00000099393.2
Hps6
Hermansky-Pudlak syndrome 6
chr16_-_28929658 0.947 ENSMUST00000100023.1
Mb21d2
Mab-21 domain containing 2
chr6_-_125494754 0.938 ENSMUST00000032492.8
Cd9
CD9 antigen
chr1_+_11414089 0.935 ENSMUST00000048613.7
ENSMUST00000171690.2
ENSMUST00000137824.1
ENSMUST00000135014.1
ENSMUST00000179089.1
A830018L16Rik



A830018L16Rik
RIKEN cDNA A830018L16 gene



RIKEN cDNA A830018L16 gene
chr6_+_97210689 0.933 ENSMUST00000044681.6
Arl6ip5
ADP-ribosylation factor-like 6 interacting protein 5
chr8_+_83666827 0.932 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr15_-_88978958 0.921 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr7_-_140856254 0.908 ENSMUST00000026557.8
Bet1l
blocked early in transport 1 homolog (S. cerevisiae)-like
chr15_+_98092569 0.906 ENSMUST00000163507.1
Pfkm
phosphofructokinase, muscle
chr11_+_70017199 0.899 ENSMUST00000133140.1
Dlg4
discs, large homolog 4 (Drosophila)
chr4_-_141598206 0.893 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr7_-_126897424 0.862 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chr11_-_35798884 0.852 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr18_+_65698253 0.798 ENSMUST00000115097.1
ENSMUST00000117694.1
Oacyl

O-acyltransferase like

chr4_-_132884509 0.778 ENSMUST00000030698.4
Stx12
syntaxin 12
chr16_-_31081363 0.776 ENSMUST00000055389.7
Xxylt1
xyloside xylosyltransferase 1
chr7_-_35556304 0.776 ENSMUST00000040962.5
Nudt19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr11_-_101987004 0.773 ENSMUST00000107173.2
ENSMUST00000107172.1
Dusp3

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)

chr19_-_4121536 0.762 ENSMUST00000025767.7
Aip
aryl-hydrocarbon receptor-interacting protein
chr13_+_30136529 0.760 ENSMUST00000152798.1
Mboat1
membrane bound O-acyltransferase domain containing 1
chr4_+_149586432 0.753 ENSMUST00000105691.1
Clstn1
calsyntenin 1
chr11_+_70017085 0.743 ENSMUST00000108589.2
Dlg4
discs, large homolog 4 (Drosophila)
chr11_+_72689997 0.723 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr2_-_32353283 0.714 ENSMUST00000091089.5
ENSMUST00000113350.1
Dnm1

dynamin 1

chr3_-_89245829 0.709 ENSMUST00000041022.8
Trim46
tripartite motif-containing 46
chr7_-_19359477 0.708 ENSMUST00000047036.8
Cd3eap
CD3E antigen, epsilon polypeptide associated protein
chr12_+_69241832 0.702 ENSMUST00000063445.6
Klhdc1
kelch domain containing 1
chr19_-_10881677 0.678 ENSMUST00000128835.1
Tmem109
transmembrane protein 109
chr8_+_113635550 0.672 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr8_+_104340594 0.668 ENSMUST00000034343.4
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr19_-_10881723 0.666 ENSMUST00000144681.1
Tmem109
transmembrane protein 109
chr19_+_45047557 0.661 ENSMUST00000062213.5
ENSMUST00000111954.4
ENSMUST00000084493.6
Sfxn3


sideroflexin 3


chr7_-_79743034 0.660 ENSMUST00000032761.7
Pex11a
peroxisomal biogenesis factor 11 alpha
chr8_+_113635787 0.659 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr5_+_143363890 0.652 ENSMUST00000010969.8
Grid2ip
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chr2_-_130424673 0.638 ENSMUST00000110277.1
Pced1a
PC-esterase domain containing 1A
chr8_+_94772009 0.635 ENSMUST00000034230.5
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr6_-_92534855 0.634 ENSMUST00000113446.1
Prickle2
prickle homolog 2 (Drosophila)
chr5_+_19227046 0.621 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_+_37046555 0.618 ENSMUST00000172789.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_70647258 0.615 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr4_-_40239700 0.603 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_-_108032069 0.600 ENSMUST00000106709.2
Podn
podocan
chr15_-_76307231 0.596 ENSMUST00000023222.6
ENSMUST00000164189.1
Oplah

5-oxoprolinase (ATP-hydrolysing)

chr7_+_80269632 0.587 ENSMUST00000032749.5
Vps33b
vacuolar protein sorting 33B (yeast)
chr7_-_7136755 0.586 ENSMUST00000032622.7
Zfp773
zinc finger protein 773
chr2_+_10153563 0.586 ENSMUST00000026886.7
Itih5
inter-alpha (globulin) inhibitor H5
chrX_+_99821021 0.579 ENSMUST00000096363.2
Tmem28
transmembrane protein 28
chr11_-_109722214 0.568 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr5_+_135009152 0.558 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chr1_-_193130201 0.546 ENSMUST00000085555.1
Diexf
digestive organ expansion factor homolog (zebrafish)
chr10_+_81628702 0.540 ENSMUST00000129622.1
Ankrd24
ankyrin repeat domain 24
chr6_+_125494419 0.536 ENSMUST00000181266.1
Gm26728
predicted gene, 26728
chr7_-_24587612 0.525 ENSMUST00000094705.2
Zfp575
zinc finger protein 575
chr11_-_5741141 0.524 ENSMUST00000140922.1
ENSMUST00000093362.5
Urgcp

upregulator of cell proliferation

chr11_-_32267547 0.517 ENSMUST00000109389.2
ENSMUST00000129010.1
ENSMUST00000020530.5
Nprl3


nitrogen permease regulator-like 3


chr18_-_80934054 0.498 ENSMUST00000091790.3
Atp9b
ATPase, class II, type 9B
chr8_+_112011359 0.493 ENSMUST00000052138.9
Terf2ip
telomeric repeat binding factor 2, interacting protein
chr2_+_32363004 0.488 ENSMUST00000132028.1
ENSMUST00000136079.1
Ciz1

CDKN1A interacting zinc finger protein 1

chr3_-_67463828 0.485 ENSMUST00000058981.2
Lxn
latexin
chr1_+_179961110 0.483 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr14_+_54360826 0.458 ENSMUST00000000985.5
Oxa1l
oxidase assembly 1-like
chr9_-_58313189 0.455 ENSMUST00000061799.8
Loxl1
lysyl oxidase-like 1
chr4_-_108031938 0.452 ENSMUST00000106708.1
Podn
podocan
chr11_+_49250583 0.445 ENSMUST00000129588.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chr3_-_87768932 0.445 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
Pear1




platelet endothelial aggregation receptor 1




chr9_-_86695897 0.428 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr8_-_13200576 0.420 ENSMUST00000165605.2
Grtp1
GH regulated TBC protein 1
chr6_+_49367739 0.419 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
Fam221a


family with sequence similarity 221, member A


chr16_-_18413452 0.411 ENSMUST00000165430.1
ENSMUST00000147720.1
Comt

catechol-O-methyltransferase

chr13_+_55622999 0.401 ENSMUST00000021963.4
Caml
calcium modulating ligand
chr19_+_8741413 0.396 ENSMUST00000176381.1
Stx5a
syntaxin 5A
chr8_+_125730005 0.394 ENSMUST00000143504.1
Ntpcr
nucleoside-triphosphatase, cancer-related
chr1_-_121332571 0.393 ENSMUST00000071064.6
Insig2
insulin induced gene 2
chr7_+_43579577 0.386 ENSMUST00000058104.7
Zfp719
zinc finger protein 719
chr11_+_87581041 0.382 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
Sept4


septin 4


chr2_-_91182848 0.381 ENSMUST00000111370.2
ENSMUST00000111376.1
ENSMUST00000099723.2
Madd


MAP-kinase activating death domain


chr11_-_69560186 0.379 ENSMUST00000004036.5
Efnb3
ephrin B3
chr13_-_99344652 0.376 ENSMUST00000022153.6
Ptcd2
pentatricopeptide repeat domain 2
chr5_+_122707546 0.374 ENSMUST00000081554.6
ENSMUST00000031429.7
ENSMUST00000139631.1
ENSMUST00000142664.1
P2rx4



purinergic receptor P2X, ligand-gated ion channel 4



chr2_+_130424321 0.363 ENSMUST00000128994.1
ENSMUST00000028900.9
Vps16

vacuolar protein sorting 16 (yeast)

chr6_-_29216301 0.361 ENSMUST00000162739.1
ENSMUST00000162099.1
ENSMUST00000159124.1
Impdh1


inosine 5'-phosphate dehydrogenase 1


chr2_+_120629113 0.360 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr11_+_51763682 0.359 ENSMUST00000020653.5
Sar1b
SAR1 gene homolog B (S. cerevisiae)
chr13_-_66852017 0.358 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr5_-_110839575 0.358 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr1_-_193035651 0.352 ENSMUST00000016344.7
Syt14
synaptotagmin XIV
chr7_-_141434402 0.347 ENSMUST00000136354.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr10_-_127211528 0.344 ENSMUST00000013970.7
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr2_+_32363163 0.336 ENSMUST00000145635.1
Ciz1
CDKN1A interacting zinc finger protein 1
chr2_+_28447941 0.328 ENSMUST00000040324.7
Ppp1r26
protein phosphatase 1, regulatory subunit 26
chrX_+_153139941 0.328 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr9_-_101034892 0.326 ENSMUST00000035116.5
Pccb
propionyl Coenzyme A carboxylase, beta polypeptide
chr4_-_4138817 0.325 ENSMUST00000133567.1
Penk
preproenkephalin
chr17_+_34031787 0.325 ENSMUST00000044858.8
Rxrb
retinoid X receptor beta
chr6_-_124863877 0.325 ENSMUST00000046893.7
Gpr162
G protein-coupled receptor 162
chr19_-_10101501 0.324 ENSMUST00000025567.7
Fads2
fatty acid desaturase 2
chr4_+_115828061 0.322 ENSMUST00000030477.3
Mob3c
MOB kinase activator 3C
chr5_-_144223516 0.321 ENSMUST00000085701.6
Tecpr1
tectonin beta-propeller repeat containing 1
chr4_-_4138432 0.320 ENSMUST00000070375.7
Penk
preproenkephalin
chr2_-_167062981 0.318 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr19_-_6067785 0.318 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
Tm7sf2






transmembrane 7 superfamily member 2






chr2_-_166581969 0.316 ENSMUST00000109246.1
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr6_+_125049903 0.308 ENSMUST00000112413.1
Acrbp
proacrosin binding protein
chr15_+_102102926 0.308 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr2_-_164404606 0.292 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
Matn4


matrilin 4


chr11_+_4883186 0.291 ENSMUST00000139737.1
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr8_+_85083269 0.290 ENSMUST00000034121.9
Man2b1
mannosidase 2, alpha B1
chr10_+_43479140 0.283 ENSMUST00000167488.1
ENSMUST00000040147.7
Bend3

BEN domain containing 3

chr7_-_44306903 0.280 ENSMUST00000004587.9
Clec11a
C-type lectin domain family 11, member a
chr17_-_75551838 0.256 ENSMUST00000112507.3
Fam98a
family with sequence similarity 98, member A
chr7_+_122965636 0.253 ENSMUST00000148880.1
Rbbp6
retinoblastoma binding protein 6
chr2_+_26330391 0.253 ENSMUST00000114134.2
ENSMUST00000127453.1
Gpsm1

G-protein signalling modulator 1 (AGS3-like, C. elegans)

chr17_+_87078255 0.250 ENSMUST00000090731.5
Gm5499
predicted pseudogene 5499
chr14_+_51893610 0.245 ENSMUST00000047726.5
ENSMUST00000161888.1
Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr11_+_49250512 0.239 ENSMUST00000101293.4
Mgat1
mannoside acetylglucosaminyltransferase 1
chr1_-_161070613 0.233 ENSMUST00000035430.3
Dars2
aspartyl-tRNA synthetase 2 (mitochondrial)
chr2_-_35461247 0.228 ENSMUST00000113001.2
ENSMUST00000113002.2
Ggta1

glycoprotein galactosyltransferase alpha 1, 3

chr16_-_70382385 0.217 ENSMUST00000072455.4
4930423O20Rik
RIKEN cDNA 4930423O20 gene
chr7_+_92741603 0.210 ENSMUST00000032879.7
Rab30
RAB30, member RAS oncogene family
chr8_+_106510853 0.207 ENSMUST00000080797.6
Cdh3
cadherin 3
chr2_+_35691893 0.205 ENSMUST00000065001.5
Dab2ip
disabled 2 interacting protein
chr4_-_130359915 0.200 ENSMUST00000134159.2
Zcchc17
zinc finger, CCHC domain containing 17
chr1_-_121332545 0.195 ENSMUST00000161068.1
Insig2
insulin induced gene 2
chr12_+_58211772 0.192 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr6_+_83034173 0.186 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr2_-_153632679 0.185 ENSMUST00000109782.1
Commd7
COMM domain containing 7
chr2_+_177904285 0.179 ENSMUST00000099001.3
Gm14327
predicted gene 14327
chr6_-_72380416 0.174 ENSMUST00000101285.3
ENSMUST00000074231.3
Vamp5

vesicle-associated membrane protein 5

chr9_-_52679429 0.174 ENSMUST00000098768.2
AI593442
expressed sequence AI593442
chr4_-_56802265 0.173 ENSMUST00000030140.2
Ikbkap
inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
chr11_+_109650921 0.169 ENSMUST00000049527.6
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr13_+_99344775 0.165 ENSMUST00000052249.5
Mrps27
mitochondrial ribosomal protein S27
chr9_+_103112072 0.163 ENSMUST00000035155.6
Rab6b
RAB6B, member RAS oncogene family
chr5_+_63649335 0.149 ENSMUST00000159584.1
3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr4_-_40702893 0.147 ENSMUST00000068125.4
Aptx
aprataxin
chr1_-_88008520 0.146 ENSMUST00000040783.4
Usp40
ubiquitin specific peptidase 40
chr7_-_79842287 0.144 ENSMUST00000049004.6
Anpep
alanyl (membrane) aminopeptidase
chr9_+_123150941 0.144 ENSMUST00000026890.4
Clec3b
C-type lectin domain family 3, member b
chr18_+_73863672 0.129 ENSMUST00000134847.1
Mro
maestro

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.7 2.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.6 2.2 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.5 1.9 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.4 1.3 GO:0019085 early viral transcription(GO:0019085)
0.4 1.7 GO:0009597 detection of virus(GO:0009597)
0.4 1.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.4 1.2 GO:0003289 endocardial cushion fusion(GO:0003274) atrial septum primum morphogenesis(GO:0003289)
0.4 4.5 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.4 2.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.0 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.3 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 2.7 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.3 3.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 1.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.3 0.8 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.2 6.0 GO:0035641 locomotory exploration behavior(GO:0035641)
0.2 2.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.4 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.2 1.0 GO:0001927 exocyst assembly(GO:0001927)
0.2 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 0.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 0.5 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 1.0 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.2 2.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.6 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 0.9 GO:0030913 paranodal junction assembly(GO:0030913)
0.2 0.9 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.2 0.8 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.2 0.5 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.9 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.1 1.0 GO:0044838 germ-line stem cell population maintenance(GO:0030718) cell quiescence(GO:0044838)
0.1 1.2 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.8 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.4 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 0.7 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 3.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.7 GO:0016557 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1 0.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.2 GO:0051794 regulation of catagen(GO:0051794)
0.1 0.6 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.1 0.6 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.2 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.9 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.4 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.3 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.7 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.2 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.1 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.6 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.4 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.7 GO:0099612 protein localization to axon(GO:0099612)
0.0 1.0 GO:0001963 synaptic transmission, dopaminergic(GO:0001963)
0.0 0.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 1.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.8 GO:0048278 vesicle docking(GO:0048278)
0.0 0.9 GO:0032418 lysosome localization(GO:0032418)
0.0 0.5 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098) I-kappaB phosphorylation(GO:0007252)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.0 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0 0.3 GO:0001893 maternal placenta development(GO:0001893)
0.0 1.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:2000858 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0048179 activin receptor complex(GO:0048179)
0.3 7.7 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.3 1.0 GO:0035339 SPOTS complex(GO:0035339)
0.3 3.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.9 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 0.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.7 GO:1990769 proximal neuron projection(GO:1990769)
0.2 0.6 GO:0032280 symmetric synapse(GO:0032280)
0.2 3.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 0.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.1 GO:0042581 specific granule(GO:0042581)
0.1 0.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 2.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.7 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 2.2 GO:0005605 basal lamina(GO:0005605)
0.1 0.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 1.2 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 2.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0097227 sperm annulus(GO:0097227)
0.1 2.2 GO:0097440 apical dendrite(GO:0097440)
0.1 1.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.0 GO:0000145 exocyst(GO:0000145)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 6.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 3.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0071920 cleavage body(GO:0071920)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 2.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 3.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.3 GO:0042641 actomyosin(GO:0042641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 3.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 1.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.4 1.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.4 3.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.3 1.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 1.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.3 3.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3 0.8 GO:0036004 GAF domain binding(GO:0036004)
0.3 3.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 0.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 2.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 1.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 0.9 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.2 7.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 0.8 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.6 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.3 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.3 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 0.9 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967) DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.8 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 1.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 3.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 2.6 GO:0000149 SNARE binding(GO:0000149)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 2.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0070492 sialic acid binding(GO:0033691) oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559) mannose binding(GO:0005537)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.3 GO:0005244 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID_ALK2_PATHWAY ALK2 signaling events
0.1 1.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 3.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 3.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 3.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 4.1 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 3.0 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 4.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.7 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 2.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.1 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 6.0 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 6.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 2.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.7 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.7 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.0 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 0.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 0.8 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 2.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.0 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases