Motif ID: Nr2c2

Z-value: 1.142


Transcription factors associated with Nr2c2:

Gene SymbolEntrez IDGene Name
Nr2c2 ENSMUSG00000005893.8 Nr2c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c2mm10_v2_chr6_+_92091378_92091390-0.671.9e-08Click!


Activity profile for motif Nr2c2.

activity profile for motif Nr2c2


Sorted Z-values histogram for motif Nr2c2

Sorted Z-values for motif Nr2c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_120120138 13.635 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr4_-_97778042 10.741 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr13_-_24761861 10.212 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr10_-_88146867 9.485 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr7_+_79500081 9.266 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr7_+_79500018 9.143 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr11_+_61485431 8.966 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr1_-_133424377 8.752 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr14_-_52020698 8.209 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chr6_-_95718800 7.589 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr1_-_172219715 7.388 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr1_+_191821444 7.333 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr17_+_35049966 7.141 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr14_+_65806066 7.082 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr8_+_88521344 6.787 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr1_-_138847579 6.627 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr17_-_56830916 6.624 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr18_-_74207771 6.407 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr2_+_118598209 6.393 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr17_+_56303321 6.388 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr3_+_88081997 6.237 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr14_+_65805832 6.235 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr11_+_80300866 6.140 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr4_-_41697040 6.072 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr10_-_13324160 6.039 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr1_-_163289214 6.030 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr2_+_164769892 5.959 ENSMUST00000088248.6
ENSMUST00000001439.6
Ube2c

ubiquitin-conjugating enzyme E2C

chr11_-_77894096 5.823 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr1_-_120120937 5.792 ENSMUST00000151708.1
Dbi
diazepam binding inhibitor
chr10_+_84756055 5.695 ENSMUST00000060397.6
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr17_+_56303396 5.692 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr10_+_88147061 5.583 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr6_-_48841373 5.551 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr19_+_38395980 5.535 ENSMUST00000054098.2
Slc35g1
solute carrier family 35, member G1
chr6_+_48841476 5.534 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr6_+_124830217 5.518 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr2_-_91931696 5.372 ENSMUST00000090602.5
Mdk
midkine
chr10_+_88146992 5.313 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr2_-_91931774 5.295 ENSMUST00000069423.6
Mdk
midkine
chr14_+_46832127 5.271 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr6_+_48841633 5.243 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr7_-_48881596 5.242 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr1_-_20820213 5.209 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr2_-_91931675 5.126 ENSMUST00000111309.1
Mdk
midkine
chr4_+_59581563 4.996 ENSMUST00000030078.5
Hsdl2
hydroxysteroid dehydrogenase like 2
chr1_-_9700209 4.988 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr10_-_13324250 4.968 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr3_-_52104891 4.842 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr10_+_93641041 4.705 ENSMUST00000020204.4
Ntn4
netrin 4
chr1_+_166254095 4.605 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr4_+_59581645 4.594 ENSMUST00000107528.1
Hsdl2
hydroxysteroid dehydrogenase like 2
chr8_-_105707933 4.579 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr1_-_170306332 4.464 ENSMUST00000179801.1
Gm7694
predicted gene 7694
chr4_-_137766474 4.430 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr15_-_10713537 4.392 ENSMUST00000090339.3
Rai14
retinoic acid induced 14
chr11_-_90002881 4.383 ENSMUST00000020864.8
Pctp
phosphatidylcholine transfer protein
chr3_-_100969644 4.371 ENSMUST00000076941.5
Ttf2
transcription termination factor, RNA polymerase II
chr1_+_136467958 4.347 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr15_+_79028212 4.286 ENSMUST00000180086.1
H1f0
H1 histone family, member 0
chr5_-_30105359 4.258 ENSMUST00000127749.3
3110082J24Rik
RIKEN cDNA 3110082J24 gene
chr3_+_94342092 4.218 ENSMUST00000029794.5
Them5
thioesterase superfamily member 5
chr11_+_117331719 4.032 ENSMUST00000100193.1
Sept9
septin 9
chr17_-_25570678 3.963 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr3_-_89418287 3.834 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr7_+_43444104 3.595 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr1_+_131527901 3.594 ENSMUST00000068613.4
Fam72a
family with sequence similarity 72, member A
chr2_+_165655237 3.564 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr4_+_101419277 3.545 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4


adenylate kinase 4


chr10_+_128790903 3.514 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr1_-_44101661 3.510 ENSMUST00000152239.1
Tex30
testis expressed 30
chr7_-_132813528 3.496 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr2_+_174415804 3.488 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr1_-_44101982 3.452 ENSMUST00000127923.1
Tex30
testis expressed 30
chr19_+_46707443 3.423 ENSMUST00000003655.7
As3mt
arsenic (+3 oxidation state) methyltransferase
chr4_+_41760454 3.405 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr10_-_80399478 3.387 ENSMUST00000092295.3
ENSMUST00000105349.1
Mbd3

methyl-CpG binding domain protein 3

chr3_+_137864573 3.366 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr17_+_57249450 3.318 ENSMUST00000019631.9
Trip10
thyroid hormone receptor interactor 10
chr1_-_192771060 3.294 ENSMUST00000128619.1
ENSMUST00000044190.5
Hhat

hedgehog acyltransferase

chr2_+_91259822 3.251 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr1_-_172206775 3.205 ENSMUST00000013842.5
ENSMUST00000111247.1
Pea15a

phosphoprotein enriched in astrocytes 15A

chr12_+_3954943 3.193 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr10_-_80399389 3.083 ENSMUST00000105348.1
Mbd3
methyl-CpG binding domain protein 3
chr19_-_43912392 3.076 ENSMUST00000026209.4
Dnmbp
dynamin binding protein
chr1_-_44102362 3.075 ENSMUST00000147571.1
ENSMUST00000027215.5
ENSMUST00000147661.1
Tex30


testis expressed 30


chr14_+_75455957 3.067 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr4_-_134767940 3.025 ENSMUST00000037828.6
Ldlrap1
low density lipoprotein receptor adaptor protein 1
chr12_-_54999102 3.011 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr6_+_71282280 2.996 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr1_-_44102414 2.969 ENSMUST00000143327.1
ENSMUST00000133677.1
Tex30

testis expressed 30

chr11_-_100850724 2.966 ENSMUST00000004143.2
Stat5b
signal transducer and activator of transcription 5B
chr1_-_44102433 2.954 ENSMUST00000129702.1
ENSMUST00000149502.1
ENSMUST00000156392.1
ENSMUST00000150911.1
Tex30



testis expressed 30



chr8_-_123318553 2.948 ENSMUST00000118395.1
ENSMUST00000035495.8
Fanca

Fanconi anemia, complementation group A

chr1_+_12718496 2.893 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr11_-_106272927 2.890 ENSMUST00000021052.9
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr3_-_153944425 2.885 ENSMUST00000150070.1
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr9_+_65630552 2.880 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr17_-_31277327 2.860 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr19_+_59260878 2.848 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr14_+_55853997 2.844 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr5_-_34169409 2.831 ENSMUST00000042954.7
ENSMUST00000060049.6
Poln
Haus3
DNA polymerase N
HAUS augmin-like complex, subunit 3
chr13_-_59675754 2.810 ENSMUST00000022039.5
ENSMUST00000095739.2
Golm1

golgi membrane protein 1

chr13_-_55571118 2.791 ENSMUST00000021957.6
Fam193b
family with sequence similarity 193, member B
chr4_+_97777606 2.780 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr17_-_35132050 2.724 ENSMUST00000025249.6
Apom
apolipoprotein M
chr1_-_119648903 2.706 ENSMUST00000163147.1
ENSMUST00000052404.6
ENSMUST00000027632.7
Epb4.1l5


erythrocyte protein band 4.1-like 5


chr9_-_124424154 2.700 ENSMUST00000180270.1
Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr7_+_27258725 2.690 ENSMUST00000079258.6
Numbl
numb-like
chr9_+_119402444 2.687 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr1_-_172027269 2.666 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr6_+_29694204 2.657 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr7_+_44465391 2.649 ENSMUST00000035929.4
ENSMUST00000146128.1
Aspdh

aspartate dehydrogenase domain containing

chr19_-_50678485 2.638 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr19_+_6975048 2.631 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_-_132813095 2.606 ENSMUST00000106165.1
Fam53b
family with sequence similarity 53, member B
chr12_-_111672290 2.599 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr12_+_17690793 2.574 ENSMUST00000071858.3
Hpcal1
hippocalcin-like 1
chr3_-_115888086 2.567 ENSMUST00000067500.5
A930005H10Rik
RIKEN cDNA A930005H10 gene
chr5_-_110779937 2.559 ENSMUST00000112426.1
Pus1
pseudouridine synthase 1
chr2_+_158794807 2.500 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr1_-_172206684 2.488 ENSMUST00000155109.1
Pea15a
phosphoprotein enriched in astrocytes 15A
chr14_+_55854115 2.485 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr7_-_126800036 2.479 ENSMUST00000133514.1
ENSMUST00000151137.1
Aldoa

aldolase A, fructose-bisphosphate

chr1_+_72824482 2.471 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr7_+_31059342 2.466 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr5_-_110780569 2.460 ENSMUST00000149208.1
ENSMUST00000031483.8
ENSMUST00000086643.5
ENSMUST00000170468.1
ENSMUST00000031481.6
Pus1




pseudouridine synthase 1




chr2_+_163658370 2.458 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
Pkig





protein kinase inhibitor, gamma





chr4_+_97777780 2.440 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr5_+_36484578 2.432 ENSMUST00000060100.1
Ccdc96
coiled-coil domain containing 96
chr1_+_132316112 2.408 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chr7_-_44548733 2.336 ENSMUST00000145956.1
ENSMUST00000049343.8
Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr7_-_126800354 2.319 ENSMUST00000106348.1
Aldoa
aldolase A, fructose-bisphosphate
chr9_-_99876147 2.315 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr5_+_53590453 2.314 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr10_+_77581720 2.300 ENSMUST00000009435.5
Pttg1ip
pituitary tumor-transforming 1 interacting protein
chr17_-_34028044 2.244 ENSMUST00000045467.7
ENSMUST00000114303.3
H2-Ke6

H2-K region expressed gene 6

chr8_+_70282978 2.206 ENSMUST00000110124.2
Homer3
homer homolog 3 (Drosophila)
chr4_+_101419696 2.170 ENSMUST00000131397.1
ENSMUST00000133055.1
Ak4

adenylate kinase 4

chr4_+_110397661 2.159 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr11_+_101442440 2.153 ENSMUST00000107249.1
Rpl27
ribosomal protein L27
chr11_+_101442298 2.152 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr14_+_57798182 2.141 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr2_-_84743655 2.138 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr7_-_23947237 2.137 ENSMUST00000086013.2
Gm10175
predicted gene 10175
chr14_+_31217850 2.134 ENSMUST00000090180.2
Sema3g
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr8_-_84662841 2.122 ENSMUST00000060427.4
Ier2
immediate early response 2
chr7_-_143460989 2.082 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr11_+_23666007 2.063 ENSMUST00000058163.4
Pus10
pseudouridylate synthase 10
chr16_+_90826719 2.058 ENSMUST00000099548.2
Eva1c
eva-1 homolog C (C. elegans)
chr18_-_88927447 2.054 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr3_-_8923796 2.043 ENSMUST00000042148.5
Mrps28
mitochondrial ribosomal protein S28
chr10_-_127288999 2.032 ENSMUST00000119078.1
Mbd6
methyl-CpG binding domain protein 6
chr19_+_45015168 2.031 ENSMUST00000039016.6
Lzts2
leucine zipper, putative tumor suppressor 2
chr18_-_36744518 2.013 ENSMUST00000014438.4
Ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr4_+_130055010 2.013 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chr5_-_137116177 2.000 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr19_-_8929323 1.990 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr11_-_70656467 1.980 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr18_-_70472429 1.975 ENSMUST00000067556.3
4930503L19Rik
RIKEN cDNA 4930503L19 gene
chr9_+_107576915 1.947 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr4_+_110397764 1.937 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr8_-_116993459 1.931 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr17_+_27029259 1.907 ENSMUST00000053683.6
Ggnbp1
gametogenetin binding protein 1
chr15_-_89425856 1.904 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chrX_-_134541847 1.896 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr15_-_76009440 1.865 ENSMUST00000170153.1
Fam83h
family with sequence similarity 83, member H
chr19_+_36554661 1.841 ENSMUST00000169036.2
ENSMUST00000047247.5
Hectd2

HECT domain containing 2

chr19_+_5474681 1.796 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr10_+_77581774 1.790 ENSMUST00000162429.1
Pttg1ip
pituitary tumor-transforming 1 interacting protein
chr10_+_93589413 1.778 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr7_+_45639964 1.776 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr9_-_106158109 1.771 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr11_-_78751656 1.762 ENSMUST00000059468.4
Fam58b
family with sequence similarity 58, member B
chr1_-_183221529 1.761 ENSMUST00000003035.5
Disp1
dispatched homolog 1 (Drosophila)
chr3_-_104818539 1.711 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr8_-_4275886 1.687 ENSMUST00000003029.7
Timm44
translocase of inner mitochondrial membrane 44
chr4_+_118428078 1.653 ENSMUST00000006557.6
ENSMUST00000167636.1
ENSMUST00000102673.4
Elovl1


elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1


chr17_-_87265866 1.653 ENSMUST00000145895.1
ENSMUST00000129616.1
ENSMUST00000155904.1
ENSMUST00000151155.1
ENSMUST00000144236.1
ENSMUST00000024963.3
Mcfd2





multiple coagulation factor deficiency 2





chr2_+_75832168 1.646 ENSMUST00000047232.7
ENSMUST00000111952.2
Agps

alkylglycerone phosphate synthase

chr12_+_108792946 1.643 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr13_-_29984219 1.622 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr4_+_118409331 1.618 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chrX_+_9885622 1.613 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr15_-_89425795 1.602 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr1_-_74284636 1.601 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr16_-_18248697 1.599 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr11_-_93955718 1.583 ENSMUST00000072566.4
Nme2
NME/NM23 nucleoside diphosphate kinase 2
chr4_-_137048695 1.532 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr11_+_69991633 1.530 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr1_+_171329376 1.515 ENSMUST00000111299.1
ENSMUST00000064950.4
Dedd

death effector domain-containing

chr11_+_23666479 1.513 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chr13_-_41358990 1.513 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr5_+_136116631 1.502 ENSMUST00000111127.1
ENSMUST00000041366.7
ENSMUST00000111129.1
Polr2j


polymerase (RNA) II (DNA directed) polypeptide J


chr4_+_118429701 1.496 ENSMUST00000067896.3
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr15_-_102189032 1.476 ENSMUST00000023805.1
Csad
cysteine sulfinic acid decarboxylase
chr3_-_58525867 1.470 ENSMUST00000029385.7
Serp1
stress-associated endoplasmic reticulum protein 1
chr2_-_25356319 1.468 ENSMUST00000028332.7
Dpp7
dipeptidylpeptidase 7
chr19_+_45015198 1.466 ENSMUST00000179108.1
Lzts2
leucine zipper, putative tumor suppressor 2
chr5_+_129725063 1.465 ENSMUST00000086046.3
Gbas
glioblastoma amplified sequence
chr11_-_101095367 1.439 ENSMUST00000019447.8
Psmc3ip
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 15.8 GO:0030421 defecation(GO:0030421)
3.9 19.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
2.5 7.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
2.3 16.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
2.1 6.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
1.9 5.8 GO:0006553 lysine metabolic process(GO:0006553)
1.8 7.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.7 5.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
1.7 6.6 GO:0035262 gonad morphogenesis(GO:0035262)
1.5 6.1 GO:0003360 brainstem development(GO:0003360)
1.3 4.0 GO:0072034 renal vesicle induction(GO:0072034)
1.3 3.9 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.3 6.3 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
1.2 2.3 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
1.1 5.7 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.1 5.5 GO:1990034 calcium ion export from cell(GO:1990034)
1.1 4.3 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.1 3.2 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.0 4.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
1.0 3.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
1.0 9.0 GO:0048251 elastic fiber assembly(GO:0048251)
1.0 3.0 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
1.0 7.8 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
1.0 2.9 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.9 4.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.9 2.7 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.9 2.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.9 12.1 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.9 8.6 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.8 7.6 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.8 8.8 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.8 2.3 GO:0045004 DNA replication proofreading(GO:0045004)
0.7 2.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.7 2.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.7 5.3 GO:0015074 DNA integration(GO:0015074)
0.7 2.6 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.6 1.9 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.6 1.9 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6 6.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.6 3.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.6 5.3 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.6 0.6 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.5 1.6 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.5 4.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.5 1.5 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.5 7.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.5 7.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.5 4.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 2.8 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.5 6.0 GO:0048664 neuron fate determination(GO:0048664)
0.4 3.6 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 2.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.4 2.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 2.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.4 5.3 GO:0001675 acrosome assembly(GO:0001675)
0.4 0.8 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.4 3.6 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.4 5.2 GO:0072189 ureter development(GO:0072189)
0.4 1.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.4 1.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.4 2.2 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086)
0.4 1.1 GO:0046032 ADP catabolic process(GO:0046032)
0.4 4.2 GO:0035336 cardiolipin metabolic process(GO:0032048) long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.3 1.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.3 1.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3 2.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.3 1.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 0.9 GO:0072174 metanephric tubule formation(GO:0072174) metanephric nephron tubule formation(GO:0072289)
0.3 1.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 1.5 GO:0019530 taurine metabolic process(GO:0019530)
0.3 1.7 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.3 3.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 3.4 GO:0009404 toxin metabolic process(GO:0009404)
0.3 1.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 0.8 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 1.6 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.3 1.8 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.3 0.8 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.3 2.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 5.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.3 1.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.2 4.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2 13.3 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.2 4.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.2 2.7 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.2 2.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.9 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.7 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.2 0.7 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.2 0.4 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 0.4 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.2 1.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.8 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.2 1.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 3.5 GO:0030574 collagen catabolic process(GO:0030574)
0.2 1.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 2.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 2.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 1.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 2.2 GO:0046697 decidualization(GO:0046697)
0.2 1.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 0.8 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.2 1.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.8 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 0.9 GO:1990839 response to endothelin(GO:1990839)
0.2 2.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 2.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 1.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.2 1.4 GO:0031053 primary miRNA processing(GO:0031053)
0.2 1.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.2 1.8 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 0.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.2 1.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.9 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 3.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 7.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 1.8 GO:0060539 diaphragm development(GO:0060539)
0.2 0.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 4.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 9.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.2 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 1.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.9 GO:2000483 detection of bacterium(GO:0016045) response to bacterial lipoprotein(GO:0032493) detection of other organism(GO:0098543) negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.6 GO:1905076 interleukin-17 secretion(GO:0072615) regulation of interleukin-17 secretion(GO:1905076) positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 2.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 5.5 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 1.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 3.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 4.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 4.4 GO:0046677 response to antibiotic(GO:0046677)
0.1 5.2 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 1.0 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 2.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 2.7 GO:0046033 AMP metabolic process(GO:0046033)
0.1 1.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 3.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 2.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 1.0 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585)
0.1 1.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 3.3 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.3 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.1 1.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 2.0 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 0.3 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 0.5 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 2.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.7 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.6 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.1 2.0 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 2.3 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 4.2 GO:0015914 phospholipid transport(GO:0015914)
0.1 3.5 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 5.5 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 0.9 GO:0007141 male meiosis I(GO:0007141) seminiferous tubule development(GO:0072520)
0.1 3.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.9 GO:0006379 mRNA cleavage(GO:0006379)
0.1 1.1 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 0.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.7 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 1.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 3.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 2.1 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.1 GO:0030224 monocyte differentiation(GO:0030224)
0.1 1.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.8 GO:0042407 cristae formation(GO:0042407)
0.1 0.4 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.1 6.5 GO:0051028 mRNA transport(GO:0051028)
0.1 1.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 1.2 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.6 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 3.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.3 GO:0050686 negative regulation of mRNA splicing, via spliceosome(GO:0048025) negative regulation of mRNA processing(GO:0050686)
0.0 1.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 5.9 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.3 GO:0051346 negative regulation of hydrolase activity(GO:0051346)
0.0 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 1.7 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.5 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 3.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.9 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.8 GO:0001754 eye photoreceptor cell differentiation(GO:0001754)
0.0 0.3 GO:0022029 cerebral cortex cell migration(GO:0021795) forebrain cell migration(GO:0021885) telencephalon cell migration(GO:0022029)
0.0 1.2 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.7 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 6.1 GO:0051604 protein maturation(GO:0051604)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.5 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.9 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 1.0 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 2.6 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.5 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 2.4 GO:0006364 rRNA processing(GO:0006364)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 1.5 GO:0006997 nucleus organization(GO:0006997)
0.0 0.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:0032620 interleukin-17 production(GO:0032620)
0.0 2.3 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.2 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0071953 elastic fiber(GO:0071953)
2.0 6.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.8 7.4 GO:0014802 terminal cisterna(GO:0014802)
1.2 4.9 GO:0032021 NELF complex(GO:0032021)
1.1 6.9 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
1.1 4.3 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
1.1 12.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.0 10.9 GO:0031080 nuclear pore outer ring(GO:0031080)
1.0 3.9 GO:0060187 cell pole(GO:0060187)
0.8 2.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.8 3.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.8 3.0 GO:0008623 CHRAC(GO:0008623)
0.7 19.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.7 2.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.5 2.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.5 3.4 GO:0001740 Barr body(GO:0001740)
0.5 4.2 GO:0061574 ASAP complex(GO:0061574)
0.5 2.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 2.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 8.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 2.9 GO:0001520 outer dense fiber(GO:0001520)
0.4 2.8 GO:0070652 HAUS complex(GO:0070652)
0.3 5.2 GO:0042555 MCM complex(GO:0042555)
0.3 4.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 1.0 GO:0031251 PAN complex(GO:0031251)
0.3 17.0 GO:0000791 euchromatin(GO:0000791)
0.3 1.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 2.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.3 6.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 1.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 4.0 GO:0031105 septin complex(GO:0031105)
0.3 2.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 4.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 1.2 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.2 6.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 0.7 GO:0055087 Ski complex(GO:0055087)
0.2 1.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 7.5 GO:0034707 chloride channel complex(GO:0034707)
0.2 1.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 3.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 2.5 GO:0005682 U5 snRNP(GO:0005682)
0.2 1.1 GO:0031415 NatA complex(GO:0031415)
0.2 2.5 GO:0031045 dense core granule(GO:0031045)
0.2 7.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.1 GO:0005687 U4 snRNP(GO:0005687)
0.1 2.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.9 GO:0045095 keratin filament(GO:0045095)
0.1 1.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.6 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.5 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 2.0 GO:0010369 chromocenter(GO:0010369)
0.1 1.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 5.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.6 GO:1904115 axon cytoplasm(GO:1904115)
0.1 23.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 7.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.8 GO:0061617 MICOS complex(GO:0061617)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 9.5 GO:0005875 microtubule associated complex(GO:0005875)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.1 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 5.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.1 GO:0001772 immunological synapse(GO:0001772)
0.1 1.5 GO:0016592 mediator complex(GO:0016592)
0.1 1.9 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 4.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 5.1 GO:0005814 centriole(GO:0005814)
0.0 1.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 17.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.6 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 6.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.9 GO:0000922 spindle pole(GO:0000922)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 1.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.1 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 3.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 5.0 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 1.1 GO:0030496 midbody(GO:0030496)
0.0 1.8 GO:0030141 secretory granule(GO:0030141)
0.0 1.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
3.0 12.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
2.5 7.6 GO:0004774 succinate-CoA ligase activity(GO:0004774)
1.9 5.7 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.5 5.8 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.2 6.2 GO:0032027 myosin light chain binding(GO:0032027)
1.2 4.8 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
1.1 4.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.0 3.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.9 2.8 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.9 3.4 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.8 4.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.7 2.9 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.7 2.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.7 3.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.6 2.6 GO:0004111 creatine kinase activity(GO:0004111)
0.6 1.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 5.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.6 2.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 4.7 GO:0043237 laminin-1 binding(GO:0043237)
0.5 8.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.5 1.9 GO:1990254 keratin filament binding(GO:1990254)
0.4 1.3 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.4 2.2 GO:0070404 NADH binding(GO:0070404)
0.4 0.4 GO:0031893 vasopressin receptor binding(GO:0031893)
0.4 4.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.4 2.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.3 1.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.3 2.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 1.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3 1.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 2.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 1.2 GO:0004064 arylesterase activity(GO:0004064)
0.3 2.7 GO:0034711 inhibin binding(GO:0034711)
0.3 4.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 6.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 3.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 4.3 GO:0003680 AT DNA binding(GO:0003680)
0.3 1.0 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.3 3.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.9 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 3.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 6.0 GO:0071837 HMG box domain binding(GO:0071837)
0.2 1.6 GO:0004673 protein histidine kinase activity(GO:0004673)
0.2 1.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 1.9 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 2.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.8 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.2 2.1 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 0.7 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 5.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 3.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.1 GO:0015197 peptide transporter activity(GO:0015197)
0.2 1.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 2.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.6 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 1.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 6.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 4.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 11.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.3 GO:0001727 lipid kinase activity(GO:0001727)
0.1 2.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 7.5 GO:0005254 chloride channel activity(GO:0005254)
0.1 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 5.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 4.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.3 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 3.3 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.1 9.9 GO:0008083 growth factor activity(GO:0008083)
0.1 1.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.3 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.1 0.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.8 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 1.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.6 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 5.3 GO:0002039 p53 binding(GO:0002039)
0.1 11.6 GO:0004386 helicase activity(GO:0004386)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 11.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 3.8 GO:0016209 antioxidant activity(GO:0016209)
0.1 1.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 3.7 GO:0008201 heparin binding(GO:0008201)
0.1 9.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 10.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.8 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 3.1 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 8.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 1.5 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.9 GO:0008168 methyltransferase activity(GO:0008168)
0.0 1.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 3.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 3.8 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 5.1 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 2.0 GO:0051087 chaperone binding(GO:0051087)
0.0 3.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 1.8 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 10.9 GO:0003677 DNA binding(GO:0003677)
0.0 1.0 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 3.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.2 8.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 9.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.2 3.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.2 6.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 14.0 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 4.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 7.4 PID_PLK1_PATHWAY PLK1 signaling events
0.1 4.9 PID_BARD1_PATHWAY BARD1 signaling events
0.1 7.7 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 8.4 PID_E2F_PATHWAY E2F transcription factor network
0.1 2.0 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 3.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 2.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.0 NABA_COLLAGENS Genes encoding collagen proteins
0.1 2.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 0.8 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 1.3 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 2.6 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 6.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.6 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.1 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.6 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 2.3 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 4.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID_P73PATHWAY p73 transcription factor network
0.0 0.8 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID_IL1_PATHWAY IL1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 11.8 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.8 19.7 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.6 3.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.5 2.1 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.4 7.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 10.9 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.3 5.2 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.3 2.8 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 3.0 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.3 4.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 5.8 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 3.4 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.2 4.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.0 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 1.9 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 11.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.2 3.0 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.2 1.7 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 1.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.9 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 3.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 2.0 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 1.9 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 4.5 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 3.4 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 0.6 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.2 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 5.6 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.9 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.3 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 3.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 0.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.5 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 0.9 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.0 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 4.2 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.3 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.4 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism