Motif ID: Nr2c2
Z-value: 1.142
Transcription factors associated with Nr2c2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr2c2 | ENSMUSG00000005893.8 | Nr2c2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr2c2 | mm10_v2_chr6_+_92091378_92091390 | -0.67 | 1.9e-08 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.3 | 15.8 | GO:0030421 | defecation(GO:0030421) |
3.9 | 19.4 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
2.5 | 7.4 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
2.3 | 16.3 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
2.1 | 6.4 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
1.9 | 5.8 | GO:0006553 | lysine metabolic process(GO:0006553) |
1.8 | 7.3 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
1.7 | 5.2 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
1.7 | 6.6 | GO:0035262 | gonad morphogenesis(GO:0035262) |
1.5 | 6.1 | GO:0003360 | brainstem development(GO:0003360) |
1.3 | 4.0 | GO:0072034 | renal vesicle induction(GO:0072034) |
1.3 | 3.9 | GO:0060489 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
1.3 | 6.3 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
1.2 | 2.3 | GO:0060853 | arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101) |
1.1 | 5.7 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
1.1 | 5.5 | GO:1990034 | calcium ion export from cell(GO:1990034) |
1.1 | 4.3 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
1.1 | 3.2 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
1.0 | 4.1 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
1.0 | 3.0 | GO:0090118 | receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) |
1.0 | 9.0 | GO:0048251 | elastic fiber assembly(GO:0048251) |
1.0 | 3.0 | GO:0046544 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544) |
1.0 | 7.8 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
1.0 | 2.9 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) |
0.9 | 4.7 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.9 | 2.7 | GO:0050748 | negative regulation of lipoprotein metabolic process(GO:0050748) |
0.9 | 2.7 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
0.9 | 12.1 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
0.9 | 8.6 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.8 | 7.6 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
0.8 | 8.8 | GO:0046643 | regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643) |
0.8 | 2.3 | GO:0045004 | DNA replication proofreading(GO:0045004) |
0.7 | 2.2 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) |
0.7 | 2.9 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.7 | 5.3 | GO:0015074 | DNA integration(GO:0015074) |
0.7 | 2.6 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.6 | 1.9 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
0.6 | 1.9 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
0.6 | 6.2 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
0.6 | 3.1 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
0.6 | 5.3 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
0.6 | 0.6 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
0.5 | 1.6 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.5 | 4.8 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.5 | 1.5 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
0.5 | 7.1 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
0.5 | 7.4 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.5 | 4.8 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.5 | 2.8 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.5 | 6.0 | GO:0048664 | neuron fate determination(GO:0048664) |
0.4 | 3.6 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.4 | 2.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.4 | 2.9 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.4 | 2.9 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
0.4 | 5.3 | GO:0001675 | acrosome assembly(GO:0001675) |
0.4 | 0.8 | GO:0072053 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
0.4 | 3.6 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.4 | 5.2 | GO:0072189 | ureter development(GO:0072189) |
0.4 | 1.1 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.4 | 1.1 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
0.4 | 2.2 | GO:0072081 | proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086) |
0.4 | 1.1 | GO:0046032 | ADP catabolic process(GO:0046032) |
0.4 | 4.2 | GO:0035336 | cardiolipin metabolic process(GO:0032048) long-chain fatty-acyl-CoA metabolic process(GO:0035336) |
0.3 | 1.3 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
0.3 | 1.0 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.3 | 2.2 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
0.3 | 1.9 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.3 | 0.9 | GO:0072174 | metanephric tubule formation(GO:0072174) metanephric nephron tubule formation(GO:0072289) |
0.3 | 1.5 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.3 | 1.5 | GO:0019530 | taurine metabolic process(GO:0019530) |
0.3 | 1.7 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.3 | 3.1 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.3 | 3.4 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.3 | 1.7 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.3 | 0.8 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.3 | 1.6 | GO:0045618 | positive regulation of keratinocyte differentiation(GO:0045618) |
0.3 | 1.8 | GO:0043383 | negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060) |
0.3 | 0.8 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
0.3 | 2.1 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
0.3 | 5.7 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.3 | 1.0 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.2 | 4.1 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
0.2 | 13.3 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
0.2 | 4.4 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
0.2 | 2.7 | GO:0060836 | lymphatic endothelial cell differentiation(GO:0060836) |
0.2 | 2.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.2 | 1.8 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
0.2 | 0.9 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
0.2 | 0.7 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.2 | 0.7 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
0.2 | 0.4 | GO:0031394 | positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
0.2 | 0.4 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
0.2 | 1.3 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.2 | 0.8 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.2 | 1.0 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.2 | 3.5 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.2 | 1.6 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
0.2 | 2.2 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
0.2 | 2.2 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.2 | 1.2 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
0.2 | 2.2 | GO:0046697 | decidualization(GO:0046697) |
0.2 | 1.2 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
0.2 | 0.8 | GO:0060161 | positive regulation of dopamine receptor signaling pathway(GO:0060161) |
0.2 | 1.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.2 | 0.8 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
0.2 | 0.9 | GO:1990839 | response to endothelin(GO:1990839) |
0.2 | 2.6 | GO:0006337 | nucleosome disassembly(GO:0006337) |
0.2 | 2.9 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.2 | 1.4 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.2 | 1.4 | GO:0031053 | primary miRNA processing(GO:0031053) |
0.2 | 1.1 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
0.2 | 1.8 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.2 | 0.4 | GO:0060700 | regulation of ribonuclease activity(GO:0060700) |
0.2 | 1.9 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.2 | 0.9 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
0.2 | 3.4 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.2 | 7.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.2 | 1.8 | GO:0060539 | diaphragm development(GO:0060539) |
0.2 | 0.6 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.2 | 1.6 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
0.2 | 4.0 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.2 | 9.8 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
0.2 | 2.1 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 0.6 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.1 | 1.5 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.1 | 1.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.1 | 0.9 | GO:2000483 | detection of bacterium(GO:0016045) response to bacterial lipoprotein(GO:0032493) detection of other organism(GO:0098543) negative regulation of interleukin-8 secretion(GO:2000483) |
0.1 | 0.6 | GO:1905076 | interleukin-17 secretion(GO:0072615) regulation of interleukin-17 secretion(GO:1905076) positive regulation of T-helper 17 type immune response(GO:2000318) |
0.1 | 2.5 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
0.1 | 5.5 | GO:0035411 | catenin import into nucleus(GO:0035411) |
0.1 | 1.3 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
0.1 | 0.6 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.1 | 1.0 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.1 | 3.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.1 | 4.9 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.1 | 4.4 | GO:0046677 | response to antibiotic(GO:0046677) |
0.1 | 5.2 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.1 | 2.0 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
0.1 | 1.0 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.1 | 2.2 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
0.1 | 2.7 | GO:0046033 | AMP metabolic process(GO:0046033) |
0.1 | 1.0 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.1 | 3.8 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
0.1 | 2.0 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
0.1 | 1.0 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
0.1 | 0.5 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
0.1 | 0.4 | GO:0002489 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) |
0.1 | 1.1 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.1 | 3.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.1 | 0.3 | GO:1903961 | positive regulation of anion transmembrane transport(GO:1903961) |
0.1 | 1.4 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
0.1 | 2.0 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
0.1 | 0.3 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.1 | 0.5 | GO:0010831 | positive regulation of myotube differentiation(GO:0010831) |
0.1 | 2.5 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.1 | 0.7 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
0.1 | 1.0 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.1 | 0.6 | GO:0050942 | positive regulation of pigment cell differentiation(GO:0050942) |
0.1 | 2.0 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
0.1 | 2.3 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
0.1 | 4.2 | GO:0015914 | phospholipid transport(GO:0015914) |
0.1 | 3.5 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
0.1 | 5.5 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.1 | 0.9 | GO:0007141 | male meiosis I(GO:0007141) seminiferous tubule development(GO:0072520) |
0.1 | 3.3 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
0.1 | 0.7 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.1 | 1.9 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.1 | 1.1 | GO:0072673 | lamellipodium morphogenesis(GO:0072673) |
0.1 | 0.5 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.1 | 0.7 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.1 | 1.9 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.1 | 3.2 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
0.1 | 0.5 | GO:0016559 | peroxisome fission(GO:0016559) |
0.1 | 0.3 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
0.1 | 0.2 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
0.1 | 0.4 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.1 | 2.1 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
0.1 | 0.2 | GO:0070459 | prolactin secretion(GO:0070459) |
0.1 | 0.5 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.1 | 1.1 | GO:0030224 | monocyte differentiation(GO:0030224) |
0.1 | 1.4 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
0.1 | 0.8 | GO:0042407 | cristae formation(GO:0042407) |
0.1 | 0.4 | GO:0045616 | regulation of keratinocyte differentiation(GO:0045616) |
0.1 | 6.5 | GO:0051028 | mRNA transport(GO:0051028) |
0.1 | 1.3 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.1 | 0.6 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.1 | 1.2 | GO:2000637 | positive regulation of gene silencing by miRNA(GO:2000637) |
0.0 | 0.6 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
0.0 | 3.9 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
0.0 | 1.3 | GO:0050686 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) negative regulation of mRNA processing(GO:0050686) |
0.0 | 1.2 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 5.9 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
0.0 | 0.3 | GO:0051346 | negative regulation of hydrolase activity(GO:0051346) |
0.0 | 0.4 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 1.7 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.5 | GO:0002031 | G-protein coupled receptor internalization(GO:0002031) |
0.0 | 0.8 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 3.5 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
0.0 | 0.9 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
0.0 | 0.4 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
0.0 | 1.2 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.8 | GO:0001754 | eye photoreceptor cell differentiation(GO:0001754) |
0.0 | 0.3 | GO:0022029 | cerebral cortex cell migration(GO:0021795) forebrain cell migration(GO:0021885) telencephalon cell migration(GO:0022029) |
0.0 | 1.2 | GO:0044380 | protein localization to cytoskeleton(GO:0044380) |
0.0 | 0.5 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.0 | 2.0 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 1.2 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 0.7 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
0.0 | 1.0 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.0 | 0.3 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
0.0 | 0.5 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.2 | GO:1903020 | positive regulation of glycoprotein metabolic process(GO:1903020) |
0.0 | 6.1 | GO:0051604 | protein maturation(GO:0051604) |
0.0 | 0.5 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
0.0 | 0.2 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
0.0 | 0.5 | GO:0043388 | positive regulation of DNA binding(GO:0043388) |
0.0 | 0.7 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.9 | GO:0048016 | inositol phosphate-mediated signaling(GO:0048016) |
0.0 | 1.0 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
0.0 | 1.1 | GO:0097120 | receptor localization to synapse(GO:0097120) |
0.0 | 2.6 | GO:0051321 | meiotic cell cycle(GO:0051321) |
0.0 | 0.5 | GO:0032006 | regulation of TOR signaling(GO:0032006) |
0.0 | 2.4 | GO:0006364 | rRNA processing(GO:0006364) |
0.0 | 0.0 | GO:0007521 | muscle cell fate determination(GO:0007521) |
0.0 | 1.5 | GO:0006997 | nucleus organization(GO:0006997) |
0.0 | 0.2 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.0 | 0.1 | GO:0032620 | interleukin-17 production(GO:0032620) |
0.0 | 2.3 | GO:0007059 | chromosome segregation(GO:0007059) |
0.0 | 0.2 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
0.0 | 0.7 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.1 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.3 | GO:2000378 | negative regulation of reactive oxygen species metabolic process(GO:2000378) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.0 | 9.0 | GO:0071953 | elastic fiber(GO:0071953) |
2.0 | 6.1 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
1.8 | 7.4 | GO:0014802 | terminal cisterna(GO:0014802) |
1.2 | 4.9 | GO:0032021 | NELF complex(GO:0032021) |
1.1 | 6.9 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
1.1 | 4.3 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
1.1 | 12.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
1.0 | 10.9 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
1.0 | 3.9 | GO:0060187 | cell pole(GO:0060187) |
0.8 | 2.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.8 | 3.0 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.8 | 3.0 | GO:0008623 | CHRAC(GO:0008623) |
0.7 | 19.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.7 | 2.7 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
0.5 | 2.0 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.5 | 3.4 | GO:0001740 | Barr body(GO:0001740) |
0.5 | 4.2 | GO:0061574 | ASAP complex(GO:0061574) |
0.5 | 2.3 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.4 | 2.7 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.4 | 8.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.4 | 2.9 | GO:0001520 | outer dense fiber(GO:0001520) |
0.4 | 2.8 | GO:0070652 | HAUS complex(GO:0070652) |
0.3 | 5.2 | GO:0042555 | MCM complex(GO:0042555) |
0.3 | 4.8 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.3 | 1.0 | GO:0031251 | PAN complex(GO:0031251) |
0.3 | 17.0 | GO:0000791 | euchromatin(GO:0000791) |
0.3 | 1.2 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.3 | 2.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.3 | 6.5 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.3 | 1.1 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
0.3 | 4.0 | GO:0031105 | septin complex(GO:0031105) |
0.3 | 2.9 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.3 | 4.4 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
0.2 | 1.2 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.2 | 6.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.2 | 0.7 | GO:0055087 | Ski complex(GO:0055087) |
0.2 | 1.1 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.2 | 1.0 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.2 | 7.5 | GO:0034707 | chloride channel complex(GO:0034707) |
0.2 | 1.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.2 | 3.0 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.2 | 2.5 | GO:0005682 | U5 snRNP(GO:0005682) |
0.2 | 1.1 | GO:0031415 | NatA complex(GO:0031415) |
0.2 | 2.5 | GO:0031045 | dense core granule(GO:0031045) |
0.2 | 7.5 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.2 | 0.9 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.2 | 1.1 | GO:0005687 | U4 snRNP(GO:0005687) |
0.1 | 2.6 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.1 | 1.9 | GO:0045095 | keratin filament(GO:0045095) |
0.1 | 1.3 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.1 | 1.6 | GO:0031011 | Ino80 complex(GO:0031011) |
0.1 | 0.5 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
0.1 | 2.0 | GO:0010369 | chromocenter(GO:0010369) |
0.1 | 1.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.1 | 5.6 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 0.5 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.1 | 1.6 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.1 | 23.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.1 | 7.3 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.1 | 0.6 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 0.8 | GO:0061617 | MICOS complex(GO:0061617) |
0.1 | 1.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 4.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.1 | 1.5 | GO:0097225 | sperm midpiece(GO:0097225) |
0.1 | 1.1 | GO:0031209 | SCAR complex(GO:0031209) |
0.1 | 9.5 | GO:0005875 | microtubule associated complex(GO:0005875) |
0.1 | 0.6 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.1 | 0.8 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 0.5 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.1 | 0.7 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.1 | 0.4 | GO:0042825 | TAP complex(GO:0042825) |
0.1 | 1.6 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.1 | 5.1 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 4.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.1 | 2.1 | GO:0001772 | immunological synapse(GO:0001772) |
0.1 | 1.5 | GO:0016592 | mediator complex(GO:0016592) |
0.1 | 1.9 | GO:1990204 | oxidoreductase complex(GO:1990204) |
0.1 | 4.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.1 | 0.5 | GO:0031931 | TORC1 complex(GO:0031931) |
0.1 | 5.1 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.3 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 17.5 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 1.6 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
0.0 | 0.8 | GO:0002080 | acrosomal membrane(GO:0002080) |
0.0 | 0.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 1.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.6 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.3 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.0 | 0.8 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.0 | 1.1 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 6.8 | GO:0005681 | spliceosomal complex(GO:0005681) |
0.0 | 1.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 1.9 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.2 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.5 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.2 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.0 | 1.9 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 1.1 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.8 | GO:0036126 | sperm flagellum(GO:0036126) |
0.0 | 1.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 3.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 1.1 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.1 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 1.1 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.9 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 5.0 | GO:0000785 | chromatin(GO:0000785) |
0.0 | 0.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.0 | 0.1 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.0 | 1.1 | GO:0030496 | midbody(GO:0030496) |
0.0 | 1.8 | GO:0030141 | secretory granule(GO:0030141) |
0.0 | 1.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 1.1 | GO:0031012 | extracellular matrix(GO:0031012) |
0.0 | 0.2 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.0 | 0.1 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.5 | 19.4 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
3.0 | 12.1 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
2.5 | 7.6 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
1.9 | 5.7 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
1.5 | 5.8 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
1.2 | 6.2 | GO:0032027 | myosin light chain binding(GO:0032027) |
1.2 | 4.8 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
1.1 | 4.4 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
1.0 | 3.8 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.9 | 2.8 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
0.9 | 3.4 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
0.8 | 4.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.7 | 2.9 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
0.7 | 2.1 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
0.7 | 3.5 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.6 | 2.6 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.6 | 1.9 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.6 | 5.0 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.6 | 2.9 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.5 | 4.7 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.5 | 8.6 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.5 | 1.9 | GO:1990254 | keratin filament binding(GO:1990254) |
0.4 | 1.3 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.4 | 2.2 | GO:0070404 | NADH binding(GO:0070404) |
0.4 | 0.4 | GO:0031893 | vasopressin receptor binding(GO:0031893) |
0.4 | 4.4 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
0.4 | 2.7 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
0.3 | 1.3 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
0.3 | 2.0 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.3 | 1.3 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.3 | 1.0 | GO:0019966 | interleukin-1 binding(GO:0019966) |
0.3 | 2.5 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.3 | 1.2 | GO:0004064 | arylesterase activity(GO:0004064) |
0.3 | 2.7 | GO:0034711 | inhibin binding(GO:0034711) |
0.3 | 4.8 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.3 | 6.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.3 | 3.1 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.3 | 4.3 | GO:0003680 | AT DNA binding(GO:0003680) |
0.3 | 1.0 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
0.3 | 3.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.2 | 1.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.2 | 1.2 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.2 | 0.9 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.2 | 3.0 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.2 | 6.0 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.2 | 1.6 | GO:0004673 | protein histidine kinase activity(GO:0004673) |
0.2 | 1.1 | GO:0030621 | U4 snRNA binding(GO:0030621) |
0.2 | 1.9 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
0.2 | 2.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.2 | 0.8 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
0.2 | 1.2 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.2 | 2.1 | GO:0038191 | neuropilin binding(GO:0038191) |
0.2 | 0.8 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.2 | 0.7 | GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
0.2 | 5.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.2 | 3.0 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.2 | 1.3 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.2 | 2.1 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.2 | 1.5 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.1 | 2.1 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.1 | 2.6 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
0.1 | 1.0 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.1 | 6.0 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.1 | 0.9 | GO:0042731 | PH domain binding(GO:0042731) |
0.1 | 1.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.1 | 4.1 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 11.5 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.1 | 1.1 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
0.1 | 1.2 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.1 | 1.3 | GO:0001727 | lipid kinase activity(GO:0001727) |
0.1 | 2.8 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.1 | 3.9 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 2.2 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
0.1 | 1.3 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.1 | 7.5 | GO:0005254 | chloride channel activity(GO:0005254) |
0.1 | 0.6 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.1 | 5.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.1 | 4.9 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
0.1 | 0.3 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.1 | 1.8 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.1 | 1.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 3.3 | GO:0016409 | palmitoyltransferase activity(GO:0016409) |
0.1 | 9.9 | GO:0008083 | growth factor activity(GO:0008083) |
0.1 | 1.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.1 | 0.3 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
0.1 | 0.9 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.1 | 1.1 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.1 | 0.7 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.1 | 0.8 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
0.1 | 1.6 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.1 | 1.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 1.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 1.6 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.1 | 0.6 | GO:0042301 | phosphate ion binding(GO:0042301) |
0.1 | 0.6 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.1 | 0.5 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.1 | 5.3 | GO:0002039 | p53 binding(GO:0002039) |
0.1 | 11.6 | GO:0004386 | helicase activity(GO:0004386) |
0.1 | 0.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.1 | 11.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.1 | 0.7 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.1 | 1.3 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 1.2 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.1 | 0.7 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
0.1 | 0.5 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 0.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.1 | 0.6 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.1 | 3.8 | GO:0016209 | antioxidant activity(GO:0016209) |
0.1 | 1.6 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.1 | 0.5 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.1 | 3.7 | GO:0008201 | heparin binding(GO:0008201) |
0.1 | 9.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.9 | GO:0001968 | fibronectin binding(GO:0001968) |
0.0 | 0.8 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.6 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 3.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.2 | GO:0008494 | translation activator activity(GO:0008494) |
0.0 | 0.5 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 10.4 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.0 | 1.0 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.2 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
0.0 | 0.8 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
0.0 | 3.1 | GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) |
0.0 | 1.1 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
0.0 | 8.1 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
0.0 | 1.5 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
0.0 | 0.9 | GO:0008168 | methyltransferase activity(GO:0008168) |
0.0 | 1.1 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.0 | 1.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 2.3 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.8 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.0 | 0.2 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 3.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 3.8 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
0.0 | 0.9 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 5.1 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
0.0 | 2.0 | GO:0051087 | chaperone binding(GO:0051087) |
0.0 | 3.9 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
0.0 | 0.3 | GO:0070403 | NAD+ binding(GO:0070403) |
0.0 | 1.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.2 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 1.0 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 2.3 | GO:0019903 | protein phosphatase binding(GO:0019903) |
0.0 | 0.3 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.0 | 1.1 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.4 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.0 | 1.8 | GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity(GO:0008757) |
0.0 | 10.9 | GO:0003677 | DNA binding(GO:0003677) |
0.0 | 1.0 | GO:0016782 | transferase activity, transferring sulfur-containing groups(GO:0016782) |
0.0 | 0.4 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.0 | 0.9 | GO:0004519 | endonuclease activity(GO:0004519) |
0.0 | 0.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.2 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.3 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 12.0 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.2 | 3.2 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.2 | 8.9 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.2 | 9.1 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
0.2 | 3.0 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.2 | 6.8 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.1 | 14.0 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.1 | 4.7 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.1 | 7.4 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.1 | 4.9 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.1 | 7.7 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.1 | 8.4 | PID_E2F_PATHWAY | E2F transcription factor network |
0.1 | 2.0 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.1 | 3.3 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.1 | 2.3 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 2.0 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.1 | 2.0 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.1 | 0.8 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.1 | 1.3 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.1 | 2.6 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
0.1 | 6.3 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.9 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 1.6 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 0.8 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 1.4 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 1.1 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 0.6 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.0 | 2.3 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.9 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 4.3 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 1.7 | PID_P73PATHWAY | p73 transcription factor network |
0.0 | 0.8 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 1.8 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.5 | PID_IL1_PATHWAY | IL1-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 11.8 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
0.8 | 19.7 | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
0.6 | 3.2 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
0.5 | 2.1 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
0.4 | 7.2 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.3 | 10.9 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.3 | 5.2 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.3 | 2.8 | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.3 | 3.0 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.3 | 4.3 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.3 | 5.8 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.3 | 3.4 | REACTOME_POL_SWITCHING | Genes involved in Polymerase switching |
0.2 | 4.2 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.2 | 3.0 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.2 | 1.9 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.2 | 11.8 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.2 | 3.0 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
0.2 | 1.7 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.2 | 1.3 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.2 | 2.5 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.1 | 2.9 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.1 | 2.7 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.1 | 3.6 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.1 | 2.0 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
0.1 | 1.9 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.1 | 4.5 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.1 | 1.2 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.1 | 2.7 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.1 | 3.4 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.1 | 0.5 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
0.1 | 0.6 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
0.1 | 1.2 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
0.1 | 0.6 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.1 | 5.6 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.1 | 1.3 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.1 | 0.5 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.1 | 1.6 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.1 | 1.5 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.1 | 0.6 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.1 | 0.9 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.1 | 1.3 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.1 | 3.2 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.1 | 0.5 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.1 | 0.5 | REACTOME_MRNA_CAPPING | Genes involved in mRNA Capping |
0.0 | 0.9 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.0 | 0.4 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.0 | 1.0 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 4.2 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 1.3 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
0.0 | 0.2 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.0 | 0.7 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.2 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
0.0 | 0.6 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
0.0 | 0.3 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.0 | 0.4 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.2 | REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ | Genes involved in Cleavage of Growing Transcript in the Termination Region |
0.0 | 0.4 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.9 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.0 | 0.7 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.3 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |