Motif ID: Nr2f1_Nr4a1
Z-value: 0.943
Transcription factors associated with Nr2f1_Nr4a1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr2f1 | ENSMUSG00000069171.7 | Nr2f1 |
Nr4a1 | ENSMUSG00000023034.6 | Nr4a1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr4a1 | mm10_v2_chr15_+_101266839_101266859 | -0.55 | 1.2e-05 | Click! |
Nr2f1 | mm10_v2_chr13_-_78197815_78197930 | 0.14 | 3.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.7 | 8.2 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
2.1 | 8.2 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
1.7 | 9.9 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
1.5 | 4.6 | GO:0042823 | pyridoxal phosphate biosynthetic process(GO:0042823) |
1.4 | 4.3 | GO:0046544 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544) |
1.2 | 5.0 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
1.2 | 4.7 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
1.1 | 4.3 | GO:0003360 | brainstem development(GO:0003360) |
1.1 | 4.2 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
1.0 | 6.1 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
1.0 | 5.9 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
0.9 | 4.6 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.9 | 2.6 | GO:0046133 | pyrimidine ribonucleoside catabolic process(GO:0046133) |
0.8 | 2.4 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
0.8 | 4.7 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.8 | 3.0 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.7 | 4.5 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
0.7 | 3.0 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
0.7 | 3.6 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
0.7 | 2.1 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
0.7 | 2.0 | GO:0030210 | heparin biosynthetic process(GO:0030210) |
0.7 | 3.4 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
0.6 | 1.9 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.6 | 1.8 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.6 | 1.8 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
0.6 | 2.9 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.6 | 1.2 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
0.6 | 1.7 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
0.6 | 1.7 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
0.6 | 1.7 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.5 | 2.2 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.5 | 2.2 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
0.5 | 1.6 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
0.5 | 1.6 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
0.5 | 2.5 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
0.5 | 5.5 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.5 | 1.4 | GO:0009814 | defense response, incompatible interaction(GO:0009814) |
0.5 | 2.3 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.4 | 1.8 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) |
0.4 | 2.2 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.4 | 1.3 | GO:0035622 | intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705) |
0.4 | 3.6 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.4 | 1.3 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
0.4 | 3.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.4 | 1.3 | GO:1902162 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) |
0.4 | 1.3 | GO:0032493 | response to bacterial lipoprotein(GO:0032493) |
0.4 | 1.7 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
0.4 | 2.0 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
0.4 | 2.4 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.4 | 1.5 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.4 | 1.8 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
0.3 | 1.0 | GO:0035672 | regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672) |
0.3 | 1.7 | GO:0015817 | glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365) |
0.3 | 2.7 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.3 | 1.4 | GO:0061198 | fungiform papilla formation(GO:0061198) |
0.3 | 8.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.3 | 1.0 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
0.3 | 1.9 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.3 | 1.9 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
0.3 | 0.9 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
0.3 | 2.2 | GO:0090234 | cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234) |
0.3 | 1.2 | GO:0035262 | gonad morphogenesis(GO:0035262) |
0.3 | 0.9 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
0.3 | 0.9 | GO:0006578 | amino-acid betaine biosynthetic process(GO:0006578) |
0.3 | 1.1 | GO:0015889 | cobalamin transport(GO:0015889) |
0.3 | 0.8 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
0.3 | 1.9 | GO:0007144 | female meiosis I(GO:0007144) |
0.3 | 0.8 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.3 | 1.3 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
0.3 | 0.8 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
0.3 | 2.1 | GO:0006105 | succinate metabolic process(GO:0006105) |
0.3 | 0.8 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
0.3 | 6.4 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.3 | 1.8 | GO:0072257 | metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307) |
0.2 | 0.7 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
0.2 | 0.7 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
0.2 | 1.5 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.2 | 0.7 | GO:0021546 | rhombomere development(GO:0021546) |
0.2 | 3.3 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.2 | 1.7 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.2 | 0.7 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.2 | 0.9 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449) |
0.2 | 0.7 | GO:0046110 | xanthine metabolic process(GO:0046110) |
0.2 | 0.7 | GO:0006106 | fumarate metabolic process(GO:0006106) |
0.2 | 1.1 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
0.2 | 0.9 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
0.2 | 0.9 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.2 | 0.4 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
0.2 | 0.7 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.2 | 2.2 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.2 | 0.9 | GO:0018343 | protein farnesylation(GO:0018343) |
0.2 | 1.7 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.2 | 3.5 | GO:0001967 | suckling behavior(GO:0001967) |
0.2 | 1.8 | GO:0046060 | dATP metabolic process(GO:0046060) |
0.2 | 5.6 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.2 | 7.1 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.2 | 0.6 | GO:0019043 | establishment of viral latency(GO:0019043) |
0.2 | 1.0 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
0.2 | 0.8 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.2 | 1.5 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.2 | 0.7 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
0.2 | 1.0 | GO:0002681 | somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) |
0.2 | 0.5 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.2 | 0.3 | GO:0003169 | coronary vein morphogenesis(GO:0003169) |
0.2 | 2.9 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
0.2 | 1.8 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.2 | 0.7 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
0.2 | 0.3 | GO:0019530 | taurine metabolic process(GO:0019530) |
0.2 | 0.5 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.2 | 5.9 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
0.2 | 0.2 | GO:0046135 | pyrimidine nucleoside catabolic process(GO:0046135) |
0.2 | 0.5 | GO:1990859 | cellular response to endothelin(GO:1990859) |
0.2 | 0.8 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.2 | 4.1 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.1 | 0.4 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
0.1 | 0.6 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.1 | 9.6 | GO:0051384 | response to glucocorticoid(GO:0051384) |
0.1 | 2.2 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 0.1 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) |
0.1 | 1.3 | GO:0043586 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) tongue development(GO:0043586) |
0.1 | 1.6 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.1 | 1.1 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
0.1 | 1.0 | GO:1903689 | regulation of wound healing, spreading of epidermal cells(GO:1903689) |
0.1 | 0.4 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
0.1 | 2.6 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
0.1 | 1.5 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.1 | 1.0 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
0.1 | 1.9 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.1 | 0.9 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.1 | 0.5 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
0.1 | 0.5 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
0.1 | 0.5 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
0.1 | 6.3 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.1 | 0.9 | GO:1903301 | regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301) |
0.1 | 0.4 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) |
0.1 | 1.1 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.1 | 1.2 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.1 | 5.4 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.1 | 1.7 | GO:0035584 | calcium-mediated signaling using intracellular calcium source(GO:0035584) |
0.1 | 1.1 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.1 | 0.2 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
0.1 | 0.2 | GO:0061344 | regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189) |
0.1 | 1.7 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.1 | 0.6 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
0.1 | 0.3 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
0.1 | 0.5 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.1 | 0.3 | GO:0098886 | modification of dendritic spine(GO:0098886) |
0.1 | 0.6 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.1 | 1.0 | GO:0046512 | sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.1 | 1.3 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.1 | 0.8 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.1 | 0.6 | GO:1903755 | regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755) |
0.1 | 1.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 0.9 | GO:0033572 | transferrin transport(GO:0033572) |
0.1 | 0.7 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.1 | 0.2 | GO:1903795 | regulation of inorganic anion transmembrane transport(GO:1903795) |
0.1 | 1.4 | GO:0002052 | positive regulation of neuroblast proliferation(GO:0002052) |
0.1 | 0.1 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
0.1 | 0.4 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.1 | 1.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
0.1 | 0.7 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
0.1 | 0.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.1 | 0.3 | GO:0000189 | MAPK import into nucleus(GO:0000189) |
0.1 | 0.8 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.1 | 0.8 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
0.1 | 3.2 | GO:0035082 | axoneme assembly(GO:0035082) |
0.1 | 0.4 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
0.1 | 0.9 | GO:0015732 | prostaglandin transport(GO:0015732) |
0.1 | 0.6 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.1 | 0.4 | GO:0060056 | mammary gland involution(GO:0060056) |
0.1 | 0.3 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
0.1 | 0.3 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
0.1 | 0.2 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
0.1 | 0.5 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.1 | 0.3 | GO:0045346 | regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347) apoptotic process involved in patterning of blood vessels(GO:1902262) |
0.1 | 0.1 | GO:0046078 | dUMP metabolic process(GO:0046078) |
0.1 | 0.3 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
0.1 | 1.0 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
0.1 | 0.7 | GO:0060539 | diaphragm development(GO:0060539) |
0.1 | 3.3 | GO:0051290 | protein heterotetramerization(GO:0051290) |
0.1 | 0.6 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.1 | 0.2 | GO:0019695 | choline metabolic process(GO:0019695) |
0.1 | 0.2 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
0.1 | 0.2 | GO:0035811 | negative regulation of urine volume(GO:0035811) |
0.1 | 0.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.1 | 0.5 | GO:0060347 | heart trabecula formation(GO:0060347) |
0.1 | 1.1 | GO:0032060 | bleb assembly(GO:0032060) |
0.1 | 1.4 | GO:0001709 | cell fate determination(GO:0001709) |
0.1 | 4.4 | GO:0046847 | filopodium assembly(GO:0046847) |
0.1 | 0.8 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 1.6 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
0.1 | 0.5 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.1 | 1.3 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
0.1 | 0.4 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
0.1 | 0.8 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.1 | 0.2 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
0.1 | 0.2 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
0.1 | 0.4 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
0.1 | 1.0 | GO:0045116 | protein neddylation(GO:0045116) |
0.1 | 0.4 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.1 | 0.4 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.1 | 1.1 | GO:0031065 | positive regulation of histone deacetylation(GO:0031065) |
0.0 | 0.5 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 0.3 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.0 | 0.8 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
0.0 | 0.6 | GO:0061436 | establishment of skin barrier(GO:0061436) |
0.0 | 0.1 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) |
0.0 | 0.2 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.0 | 0.3 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.0 | 0.4 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
0.0 | 0.5 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
0.0 | 0.1 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
0.0 | 4.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.0 | 1.0 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 2.6 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 0.6 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.0 | 0.5 | GO:0046051 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
0.0 | 0.3 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.0 | 0.2 | GO:0043649 | dicarboxylic acid catabolic process(GO:0043649) |
0.0 | 0.2 | GO:0010694 | positive regulation of alkaline phosphatase activity(GO:0010694) |
0.0 | 1.3 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
0.0 | 0.5 | GO:0090344 | negative regulation of cell aging(GO:0090344) |
0.0 | 0.3 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.0 | 0.1 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 1.1 | GO:0042026 | protein refolding(GO:0042026) |
0.0 | 1.9 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.0 | 0.4 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
0.0 | 0.0 | GO:1904956 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of mesodermal cell fate specification(GO:0042662) Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
0.0 | 0.6 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 1.0 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.0 | 0.6 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
0.0 | 2.2 | GO:0046785 | microtubule polymerization(GO:0046785) |
0.0 | 0.4 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 0.6 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.2 | GO:0051231 | mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256) |
0.0 | 0.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.0 | 0.6 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) negative regulation of collateral sprouting(GO:0048671) |
0.0 | 0.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.0 | 0.8 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.0 | 3.3 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
0.0 | 0.4 | GO:0034389 | lipid particle organization(GO:0034389) |
0.0 | 0.3 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.0 | 0.3 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.0 | 0.0 | GO:0097066 | response to thyroid hormone(GO:0097066) |
0.0 | 0.1 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
0.0 | 1.0 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.0 | 0.2 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
0.0 | 0.9 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
0.0 | 0.2 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.0 | 2.1 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
0.0 | 0.8 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
0.0 | 0.1 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
0.0 | 0.1 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.0 | 0.9 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.6 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.0 | 0.2 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476) |
0.0 | 0.1 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 0.2 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.3 | GO:0048643 | positive regulation of skeletal muscle tissue development(GO:0048643) |
0.0 | 0.2 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
0.0 | 0.2 | GO:0070508 | sterol import(GO:0035376) cholesterol import(GO:0070508) |
0.0 | 0.7 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.2 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) |
0.0 | 0.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.0 | 0.1 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
0.0 | 0.2 | GO:0050892 | intestinal absorption(GO:0050892) |
0.0 | 0.1 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) pyridine-containing compound catabolic process(GO:0072526) |
0.0 | 0.6 | GO:0030317 | sperm motility(GO:0030317) |
0.0 | 0.5 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.0 | 0.7 | GO:0051145 | smooth muscle cell differentiation(GO:0051145) |
0.0 | 0.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.0 | 0.3 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.0 | 0.3 | GO:0043507 | positive regulation of JUN kinase activity(GO:0043507) |
0.0 | 0.5 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 0.0 | GO:0060372 | regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) |
0.0 | 1.6 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 1.1 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.0 | 0.4 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.0 | 0.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.5 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
0.0 | 0.4 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.0 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 0.1 | GO:0010155 | regulation of proton transport(GO:0010155) |
0.0 | 0.3 | GO:0048255 | mRNA stabilization(GO:0048255) |
0.0 | 0.4 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
0.0 | 0.6 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
0.0 | 0.9 | GO:2000278 | regulation of DNA biosynthetic process(GO:2000278) |
0.0 | 0.1 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
0.0 | 0.8 | GO:0090090 | negative regulation of canonical Wnt signaling pathway(GO:0090090) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.8 | 2.8 | GO:0097427 | microtubule bundle(GO:0097427) |
2.0 | 6.1 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
1.8 | 5.4 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
1.5 | 5.9 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
1.4 | 4.3 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
1.1 | 4.2 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.7 | 7.4 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.7 | 3.0 | GO:0000939 | nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939) |
0.6 | 2.5 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.6 | 4.2 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.6 | 4.4 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.5 | 7.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.4 | 3.0 | GO:0097452 | GAIT complex(GO:0097452) |
0.4 | 4.6 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.4 | 1.8 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.3 | 3.1 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.3 | 5.5 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
0.3 | 1.7 | GO:0032426 | stereocilium tip(GO:0032426) |
0.3 | 0.9 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.3 | 2.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.3 | 0.9 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.3 | 12.4 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.3 | 1.8 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.2 | 4.1 | GO:0031528 | microvillus membrane(GO:0031528) |
0.2 | 2.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.2 | 5.8 | GO:0001891 | phagocytic cup(GO:0001891) |
0.2 | 2.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.2 | 2.8 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.2 | 2.4 | GO:0005915 | zonula adherens(GO:0005915) |
0.2 | 0.9 | GO:0070069 | cytochrome complex(GO:0070069) |
0.2 | 1.0 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
0.2 | 3.9 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.2 | 2.3 | GO:0005844 | polysome(GO:0005844) |
0.2 | 1.5 | GO:0031415 | NatA complex(GO:0031415) |
0.2 | 0.9 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
0.2 | 1.6 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
0.2 | 0.5 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
0.2 | 1.6 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.2 | 0.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.2 | 2.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 0.6 | GO:0032021 | NELF complex(GO:0032021) |
0.1 | 2.3 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
0.1 | 1.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.1 | 1.7 | GO:0030057 | desmosome(GO:0030057) |
0.1 | 1.2 | GO:0046930 | pore complex(GO:0046930) |
0.1 | 1.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.1 | 1.1 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.1 | 8.5 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.1 | 1.9 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 0.3 | GO:0036125 | mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125) |
0.1 | 0.6 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.1 | 0.8 | GO:0032009 | early phagosome(GO:0032009) |
0.1 | 0.6 | GO:1990356 | sumoylated E2 ligase complex(GO:1990356) |
0.1 | 1.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 0.5 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
0.1 | 0.9 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.1 | 2.5 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.1 | 0.8 | GO:0002177 | manchette(GO:0002177) |
0.1 | 0.9 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 1.9 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.1 | 0.5 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 0.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 0.2 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
0.1 | 0.5 | GO:0030056 | hemidesmosome(GO:0030056) |
0.1 | 7.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.1 | 4.1 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.1 | 0.6 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
0.1 | 1.6 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 0.7 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.1 | 0.4 | GO:0000125 | PCAF complex(GO:0000125) |
0.1 | 0.6 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.1 | 4.7 | GO:0000786 | nucleosome(GO:0000786) |
0.1 | 0.3 | GO:0097444 | spine apparatus(GO:0097444) |
0.1 | 0.3 | GO:0031983 | vesicle lumen(GO:0031983) |
0.1 | 3.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.1 | 0.8 | GO:1990635 | proximal dendrite(GO:1990635) |
0.1 | 0.4 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.1 | 1.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 0.1 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
0.1 | 10.6 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.1 | 2.9 | GO:0005882 | intermediate filament(GO:0005882) |
0.1 | 3.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.1 | 0.4 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 1.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 3.1 | GO:0000793 | condensed chromosome(GO:0000793) |
0.0 | 0.3 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.0 | 0.2 | GO:0097443 | sorting endosome(GO:0097443) |
0.0 | 0.2 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.0 | 0.5 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.3 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.8 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.0 | 0.9 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 0.7 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.2 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.0 | 2.9 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 1.6 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.6 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.0 | 0.7 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 0.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 12.2 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 1.1 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.9 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.1 | GO:0031523 | Myb complex(GO:0031523) |
0.0 | 0.5 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 1.7 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 1.6 | GO:0015934 | large ribosomal subunit(GO:0015934) |
0.0 | 1.1 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 0.2 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.3 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.2 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.0 | 0.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.0 | 6.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 2.8 | GO:0031012 | extracellular matrix(GO:0031012) |
0.0 | 0.3 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
0.0 | 1.1 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 5.3 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 0.1 | GO:0098800 | inner mitochondrial membrane protein complex(GO:0098800) |
0.0 | 1.8 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 1.2 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 0.4 | GO:0015030 | Cajal body(GO:0015030) |
0.0 | 0.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.7 | GO:0010008 | endosome membrane(GO:0010008) |
0.0 | 1.7 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 1.0 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
0.0 | 1.1 | GO:0005814 | centriole(GO:0005814) |
0.0 | 0.1 | GO:0071986 | Ragulator complex(GO:0071986) |
0.0 | 0.6 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.4 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 2.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 0.5 | GO:0030118 | clathrin coat(GO:0030118) |
0.0 | 0.1 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.1 | GO:0005642 | annulate lamellae(GO:0005642) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.0 | 5.9 | GO:0030172 | troponin C binding(GO:0030172) |
1.5 | 4.6 | GO:0031403 | lithium ion binding(GO:0031403) |
1.4 | 4.2 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
1.4 | 4.2 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
1.4 | 5.4 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
1.3 | 8.9 | GO:0001849 | complement component C1q binding(GO:0001849) |
1.1 | 7.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
1.0 | 3.0 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
1.0 | 5.0 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.9 | 10.4 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.8 | 3.4 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.8 | 2.5 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
0.8 | 2.3 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
0.7 | 2.2 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.7 | 3.4 | GO:0043532 | angiostatin binding(GO:0043532) |
0.7 | 2.0 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
0.6 | 1.9 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.6 | 2.5 | GO:1990254 | keratin filament binding(GO:1990254) |
0.6 | 3.7 | GO:0043199 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) sulfate binding(GO:0043199) |
0.6 | 4.9 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.6 | 3.6 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
0.6 | 2.9 | GO:0004359 | glutaminase activity(GO:0004359) |
0.6 | 1.7 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
0.6 | 1.7 | GO:0015182 | L-asparagine transmembrane transporter activity(GO:0015182) |
0.6 | 2.3 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.6 | 3.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.5 | 4.9 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.5 | 2.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.5 | 1.9 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
0.5 | 2.9 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.4 | 1.7 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.4 | 2.0 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
0.4 | 8.9 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.4 | 1.5 | GO:1990239 | steroid hormone binding(GO:1990239) |
0.4 | 5.7 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.4 | 2.9 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.3 | 3.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.3 | 1.4 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
0.3 | 2.0 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.3 | 1.6 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.3 | 2.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.3 | 0.9 | GO:0016015 | morphogen activity(GO:0016015) |
0.3 | 0.9 | GO:0004998 | transferrin receptor activity(GO:0004998) |
0.3 | 0.9 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.3 | 3.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.3 | 1.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.3 | 0.8 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
0.3 | 5.4 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.3 | 1.3 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
0.3 | 0.8 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.3 | 1.0 | GO:0004064 | arylesterase activity(GO:0004064) |
0.3 | 1.3 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.2 | 0.7 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
0.2 | 1.7 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.2 | 1.7 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.2 | 3.6 | GO:0003680 | AT DNA binding(GO:0003680) |
0.2 | 0.4 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
0.2 | 0.9 | GO:0070991 | medium-chain-acyl-CoA dehydrogenase activity(GO:0070991) |
0.2 | 0.7 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.2 | 0.6 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.2 | 0.8 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
0.2 | 2.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.2 | 0.6 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.2 | 1.9 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.2 | 7.5 | GO:0005109 | frizzled binding(GO:0005109) |
0.2 | 1.1 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.2 | 0.5 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
0.2 | 0.7 | GO:0043546 | molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546) |
0.2 | 0.5 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
0.2 | 1.4 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.2 | 0.9 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.2 | 1.0 | GO:0017040 | ceramidase activity(GO:0017040) |
0.2 | 1.1 | GO:0031419 | cobalamin binding(GO:0031419) |
0.2 | 1.1 | GO:0048018 | receptor agonist activity(GO:0048018) |
0.2 | 4.3 | GO:0009055 | electron carrier activity(GO:0009055) |
0.2 | 0.2 | GO:0002054 | nucleobase binding(GO:0002054) |
0.1 | 0.7 | GO:0070404 | NADH binding(GO:0070404) |
0.1 | 4.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 0.9 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.1 | 1.5 | GO:0015266 | protein channel activity(GO:0015266) |
0.1 | 3.5 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.1 | 1.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.1 | 1.0 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.1 | 0.9 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.1 | 1.5 | GO:0005167 | neurotrophin TRK receptor binding(GO:0005167) |
0.1 | 1.0 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.1 | 0.8 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
0.1 | 2.0 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 1.3 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.1 | 3.1 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.1 | 1.1 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.1 | 1.1 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.1 | 1.4 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.1 | 0.3 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.1 | 0.7 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.1 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.1 | 1.5 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.1 | 0.7 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.1 | 1.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.1 | 0.3 | GO:0008311 | double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311) |
0.1 | 2.3 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 0.6 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
0.1 | 0.4 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.1 | 16.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.1 | 5.8 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.1 | 0.5 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
0.1 | 1.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.1 | 0.8 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.1 | 0.6 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.1 | 0.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.1 | 1.2 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
0.1 | 0.8 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 0.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 0.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.4 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.1 | 0.3 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
0.1 | 0.2 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
0.1 | 0.5 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.1 | 0.6 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.1 | 0.2 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.1 | 0.2 | GO:0032052 | bile acid binding(GO:0032052) |
0.1 | 1.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 1.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.1 | 0.8 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.1 | 1.1 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.1 | 0.8 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.1 | 0.8 | GO:0008227 | G-protein coupled amine receptor activity(GO:0008227) |
0.1 | 1.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.1 | 0.6 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.1 | 5.3 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.1 | 2.6 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
0.1 | 1.4 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
0.1 | 0.3 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.1 | 2.5 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 0.5 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.1 | 0.2 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.1 | 0.5 | GO:0001848 | complement binding(GO:0001848) |
0.1 | 0.7 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.0 | 0.7 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.0 | 0.2 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
0.0 | 0.7 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 0.5 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.4 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
0.0 | 1.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 1.3 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.0 | 1.4 | GO:0001067 | regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212) |
0.0 | 3.3 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.4 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.0 | 2.8 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 2.0 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.3 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 0.9 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) |
0.0 | 0.7 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 2.2 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.8 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.0 | 0.4 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.0 | 1.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.0 | 0.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.2 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.0 | 0.2 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.0 | 0.4 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.4 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.6 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.5 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 1.0 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
0.0 | 1.9 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.0 | 0.9 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
0.0 | 0.5 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.0 | 0.5 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 0.3 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.0 | 1.0 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
0.0 | 1.5 | GO:0072341 | modified amino acid binding(GO:0072341) |
0.0 | 0.1 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.0 | 0.0 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
0.0 | 0.4 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 0.5 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.0 | 3.3 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 0.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.5 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.2 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
0.0 | 0.2 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.0 | 0.7 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 3.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 1.9 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.4 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
0.0 | 0.1 | GO:0016936 | galactoside binding(GO:0016936) |
0.0 | 1.7 | GO:0008201 | heparin binding(GO:0008201) |
0.0 | 1.1 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.0 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.0 | 1.0 | GO:0045309 | protein phosphorylated amino acid binding(GO:0045309) |
0.0 | 0.3 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.3 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.7 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 0.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.4 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.0 | 0.1 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.0 | 0.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.1 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
0.0 | 0.3 | GO:0046906 | tetrapyrrole binding(GO:0046906) |
0.0 | 1.9 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.1 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.0 | 0.1 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.0 | 0.5 | GO:0005507 | copper ion binding(GO:0005507) |
0.0 | 0.1 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
0.0 | 0.5 | GO:0061650 | ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
0.0 | 0.4 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.0 | 0.1 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.0 | 0.7 | GO:0008186 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
0.0 | 0.3 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.5 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.3 | 2.9 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.2 | 1.8 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.2 | 12.9 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.1 | 2.0 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.1 | 15.2 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.1 | 4.3 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.1 | 3.3 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.1 | 4.2 | PID_ATR_PATHWAY | ATR signaling pathway |
0.1 | 2.9 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.1 | 3.1 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.1 | 7.7 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.1 | 2.6 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.1 | 2.5 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.1 | 0.1 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.1 | 0.9 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
0.1 | 1.6 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.1 | 2.2 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.1 | 0.5 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.1 | 5.3 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 2.8 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.1 | 1.7 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.1 | 1.3 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.1 | 0.7 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 0.8 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 1.4 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 1.0 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 2.9 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.0 | 0.4 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 6.2 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.0 | 4.5 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.6 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 4.1 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 1.9 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 0.5 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 1.1 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 1.1 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.7 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.6 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 1.7 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 0.6 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 0.2 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.0 | 0.3 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 0.4 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 0.3 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 5.3 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.4 | 4.9 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.4 | 1.3 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.4 | 30.4 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.3 | 6.1 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.3 | 2.9 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
0.3 | 8.1 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.3 | 3.1 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.3 | 4.3 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.3 | 6.6 | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
0.2 | 3.2 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.2 | 8.0 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.2 | 1.5 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.2 | 15.5 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.2 | 8.8 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.2 | 1.9 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.2 | 5.7 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.2 | 3.9 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.2 | 2.6 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.1 | 1.0 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.1 | 4.2 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.1 | 5.4 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.1 | 1.1 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.1 | 2.9 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.1 | 6.9 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.1 | 1.9 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
0.1 | 1.4 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.1 | 1.8 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.1 | 3.1 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.1 | 0.8 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.1 | 1.6 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.1 | 3.2 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.1 | 2.6 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
0.1 | 1.4 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.1 | 1.3 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.1 | 0.9 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.1 | 3.8 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 0.6 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
0.1 | 0.8 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.1 | 0.6 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.1 | 4.7 | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Late Phase of HIV Life Cycle |
0.1 | 2.0 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
0.1 | 0.6 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.1 | 1.1 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.1 | 0.5 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.1 | 0.5 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.1 | 0.5 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
0.1 | 0.6 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.0 | 1.1 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.0 | 0.8 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.0 | 1.3 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 5.8 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.0 | 0.4 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.0 | 0.5 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 2.0 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 3.0 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
0.0 | 1.1 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.5 | REACTOME_CIRCADIAN_CLOCK | Genes involved in Circadian Clock |
0.0 | 1.0 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.3 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 1.4 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.4 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 0.2 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.0 | 0.7 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.5 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.6 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.2 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 0.3 | REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.0 | 0.4 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
0.0 | 0.5 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.0 | 0.9 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 1.8 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 1.2 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.2 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 0.2 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.0 | 0.3 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 0.5 | REACTOME_TRANSLATION | Genes involved in Translation |
0.0 | 0.3 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.1 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |