Motif ID: Nr2f2
Z-value: 0.673

Transcription factors associated with Nr2f2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr2f2 | ENSMUSG00000030551.7 | Nr2f2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr2f2 | mm10_v2_chr7_-_70360593_70360746 | -0.36 | 6.6e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 164 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.4 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.2 | 3.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 3.0 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
0.6 | 2.5 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
0.2 | 2.3 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.2 | 2.2 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
0.3 | 1.9 | GO:2001023 | regulation of response to drug(GO:2001023) |
0.0 | 1.9 | GO:0006836 | neurotransmitter transport(GO:0006836) |
0.4 | 1.8 | GO:1905169 | protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171) |
0.0 | 1.8 | GO:0007601 | visual perception(GO:0007601) |
0.2 | 1.7 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.1 | 1.7 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
0.1 | 1.7 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
0.0 | 1.7 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.5 | 1.6 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
0.2 | 1.6 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.0 | 1.6 | GO:0061512 | protein localization to cilium(GO:0061512) |
0.2 | 1.5 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
0.0 | 1.5 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.4 | 1.3 | GO:1902528 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 80 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 5.2 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 4.4 | GO:0005795 | Golgi stack(GO:0005795) |
0.2 | 2.5 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 2.2 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 2.1 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 2.0 | GO:0031461 | cullin-RING ubiquitin ligase complex(GO:0031461) |
0.1 | 1.9 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.0 | 1.9 | GO:0097440 | apical dendrite(GO:0097440) |
0.3 | 1.8 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.0 | 1.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.3 | 1.6 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.1 | 1.3 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.0 | 1.3 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 1.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 1.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 1.2 | GO:0099738 | cell cortex region(GO:0099738) |
0.3 | 1.1 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.1 | 1.1 | GO:0000145 | exocyst(GO:0000145) |
0.0 | 1.1 | GO:0055037 | recycling endosome(GO:0055037) |
0.2 | 1.0 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 119 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 4.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.2 | 4.4 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
0.2 | 3.0 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.3 | 2.3 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 2.3 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
0.1 | 2.1 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.1 | 2.0 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 1.9 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 1.8 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 1.8 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 1.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 1.8 | GO:0035254 | glutamate receptor binding(GO:0035254) |
0.3 | 1.7 | GO:0019841 | retinol binding(GO:0019841) |
0.3 | 1.6 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
0.0 | 1.6 | GO:0008201 | heparin binding(GO:0008201) |
0.4 | 1.5 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
0.0 | 1.5 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 1.5 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 1.4 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
Gene overrepresentation in C2:CP category:
Showing 1 to 19 of 19 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 5.9 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 2.1 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
0.0 | 2.1 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
0.0 | 2.1 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 1.8 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.0 | 1.8 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.0 | 1.2 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
0.1 | 0.7 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 0.7 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 0.7 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.5 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.0 | 0.5 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 0.4 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.0 | 0.4 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.4 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 0.4 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 0.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.0 | 0.3 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.1 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 50 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.2 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.1 | 4.0 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 4.0 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 2.3 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 1.9 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
0.1 | 1.9 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.1 | 1.7 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.0 | 1.6 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.0 | 1.6 | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
0.0 | 1.5 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 1.4 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 1.3 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 1.3 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 0.9 | REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
0.0 | 0.9 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.0 | 0.8 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
0.0 | 0.8 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 0.7 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.0 | 0.7 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.7 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |