ISMARA results: Nr4a2

Motif ID: Nr4a2

Z-value: 0.466

Transcription factors associated with Nr4a2:

Gene Symbol	Entrez ID	Gene Name
Nr4a2	ENSMUSG00000026826.7	Nr4a2

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Nr4a2	mm10_v2_chr2_-_57124003_57124071	0.52	4.2e-05	Click!

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Showing 1 to 20 of 116 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_26229707	4.926	ENSMUST00000060716.5 ENSMUST00000164660.1	Samd3	sterile alpha motif domain containing 3
chr18_+_86711059	3.729	ENSMUST00000068423.3	Cbln2	cerebellin 2 precursor protein
chr9_-_32344237	1.873	ENSMUST00000034533.5	Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5
chr2_+_121295437	1.581	ENSMUST00000110639.1	Map1a	microtubule-associated protein 1 A
chr2_-_129699833	1.454	ENSMUST00000028883.5	Pdyn	prodynorphin
chr9_-_106656081	1.419	ENSMUST00000023959.7	Grm2	glutamate receptor, metabotropic 2
chr8_+_68880491	1.272	ENSMUST00000015712.8	Lpl	lipoprotein lipase
chr13_+_94875600	1.197	ENSMUST00000022195.10	Otp	orthopedia homolog (Drosophila)
chr13_+_93304066	0.945	ENSMUST00000109493.1	Homer1	homer homolog 1 (Drosophila)
chr18_-_56975333	0.925	ENSMUST00000139243.2 ENSMUST00000025488.8	C330018D20Rik	RIKEN cDNA C330018D20 gene
chr4_-_36136463	0.882	ENSMUST00000098151.2	Lingo2	leucine rich repeat and Ig domain containing 2
chr17_+_29360923	0.813	ENSMUST00000024810.6	Fgd2	FYVE, RhoGEF and PH domain containing 2
chr6_-_99096196	0.774	ENSMUST00000175886.1	Foxp1	forkhead box P1
chr5_+_111581422	0.761	ENSMUST00000064930.3	C130026L21Rik	RIKEN cDNA C130026L21 gene
chr2_+_4976113	0.751	ENSMUST00000167607.1 ENSMUST00000115010.2	Ucma	upper zone of growth plate and cartilage matrix associated
chr6_-_124814288	0.729	ENSMUST00000172132.2	Tpi1	triosephosphate isomerase 1
chr5_+_150259922	0.728	ENSMUST00000087204.5	Fry	furry homolog (Drosophila)
chr13_+_93303757	0.713	ENSMUST00000109494.1	Homer1	homer homolog 1 (Drosophila)
chr2_+_75832168	0.681	ENSMUST00000047232.7 ENSMUST00000111952.2	Agps	alkylglycerone phosphate synthase
chr10_+_110920170	0.665	ENSMUST00000020403.5	Csrp2	cysteine and glycine-rich protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 42 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.4	1.9	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1	1.7	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.0	1.6	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	1.5	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	1.4	GO:0014047	glutamate secretion(GO:0014047)
0.3	1.3	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.4	1.2	GO:0032915	positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1	1.2	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.3	0.8	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.8	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.1	0.8	GO:0061470	interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1	0.8	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.8	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.2	0.7	GO:0019405	alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1	0.7	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.2	0.6	GO:0015866	ADP transport(GO:0015866)
0.1	0.6	GO:0032306	regulation of prostaglandin secretion(GO:0032306)
0.1	0.6	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.6	GO:0050832	defense response to fungus(GO:0050832)

Gene overrepresentation in cellular_component category:

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Showing 1 to 18 of 18 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.4	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.7	GO:0043034	costamere(GO:0043034)
0.0	1.4	GO:0042734	presynaptic membrane(GO:0042734)
0.2	1.3	GO:0042627	chylomicron(GO:0042627)
0.0	1.2	GO:0035861	site of double-strand break(GO:0035861)
0.1	0.8	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.8	GO:0016235	aggresome(GO:0016235)
0.0	0.7	GO:0005930	axoneme(GO:0005930)
0.1	0.6	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.2	0.5	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1	0.4	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.4	GO:0032156	septin cytoskeleton(GO:0032156)
0.0	0.4	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1	0.3	GO:0034715	U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0	0.3	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 28 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.9	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2	1.7	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	1.7	GO:0005518	collagen binding(GO:0005518)
0.3	1.4	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0	1.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.2	1.3	GO:0001515	opioid peptide activity(GO:0001515)
0.1	1.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	1.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.2	0.8	GO:0019808	polyamine binding(GO:0019808)
0.0	0.8	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	0.7	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1	0.6	GO:0015217	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1	0.6	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.6	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.5	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.5	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.5	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.1	0.4	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.4	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.4	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in C2:CP category:

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Showing 1 to 7 of 7 entries

Total log-likelihood	Term	Description
2.4	NABA_SECRETED_FACTORS	Genes encoding secreted soluble factors
1.9	ST_MYOCYTE_AD_PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.2	SA_B_CELL_RECEPTOR_COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.7	PID_ATF2_PATHWAY	ATF-2 transcription factor network
0.6	PID_EPHA_FWDPATHWAY	EPHA forward signaling
0.4	PID_ARF6_DOWNSTREAM_PATHWAY	Arf6 downstream pathway
0.4	PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY	Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 16 of 16 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	1.5	REACTOME_G_PROTEIN_ACTIVATION	Genes involved in G-protein activation
0.1	1.4	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	1.4	REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK	Genes involved in NRAGE signals death through JNK
0.1	1.3	REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.2	REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.2	REACTOME_SIGNALING_BY_RHO_GTPASES	Genes involved in Signaling by Rho GTPases
0.0	1.0	REACTOME_GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.7	REACTOME_PEROXISOMAL_LIPID_METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.6	REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.6	REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.5	REACTOME_METABOLISM_OF_POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.5	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME_SYNTHESIS_OF_PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)