Motif ID: Nr4a3

Z-value: 0.598


Transcription factors associated with Nr4a3:

Gene SymbolEntrez IDGene Name
Nr4a3 ENSMUSG00000028341.3 Nr4a3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a3mm10_v2_chr4_+_48045144_480451600.172.3e-01Click!


Activity profile for motif Nr4a3.

activity profile for motif Nr4a3


Sorted Z-values histogram for motif Nr4a3

Sorted Z-values for motif Nr4a3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr4a3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_154960915 5.432 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chrY_-_1245685 3.629 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
 Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr5_+_66968559 2.511 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chrY_-_1245753 2.181 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr8_+_124793013 2.027 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr8_+_124793061 1.932 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr5_+_66968416 1.910 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr9_-_54661666 1.702 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_-_55033398 1.394 ENSMUST00000108883.3
ENSMUST00000102727.2
 Anxa6

annexin A6

chr5_+_111581422 1.372 ENSMUST00000064930.3
 C130026L21Rik
RIKEN cDNA C130026L21 gene
chr7_-_109616548 1.254 ENSMUST00000077909.1
ENSMUST00000084738.3
 St5

suppression of tumorigenicity 5

chr2_+_59160838 1.092 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
 Pkp4


plakophilin 4


chr15_+_25773985 1.047 ENSMUST00000125667.1
 Myo10
myosin X
chr6_-_138426735 1.017 ENSMUST00000162932.1
 Lmo3
LIM domain only 3
chr4_+_99955715 0.962 ENSMUST00000102783.4
 Pgm2
phosphoglucomutase 2
chr3_-_104818539 0.932 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
 Mov10



Moloney leukemia virus 10



chr6_-_76497631 0.928 ENSMUST00000097218.5
 Gm9008
predicted pseudogene 9008
chr7_-_98162318 0.879 ENSMUST00000107112.1
 Capn5
calpain 5
chr15_-_79804717 0.825 ENSMUST00000023057.8
 Nptxr
neuronal pentraxin receptor
chr19_-_4334001 0.816 ENSMUST00000176653.1
 Kdm2a
lysine (K)-specific demethylase 2A
chr1_-_152386589 0.786 ENSMUST00000162371.1
 Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr7_+_102267795 0.739 ENSMUST00000033289.4
 Stim1
stromal interaction molecule 1
chr1_-_152386675 0.717 ENSMUST00000015124.8
 Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr5_+_16553488 0.673 ENSMUST00000030683.3
 Hgf
hepatocyte growth factor
chr12_+_4082574 0.632 ENSMUST00000020986.7
 Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr7_+_45896941 0.536 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr12_-_110978981 0.530 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
 Ankrd9


ankyrin repeat domain 9


chr7_+_30712209 0.529 ENSMUST00000005692.6
ENSMUST00000170371.1
 Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr10_-_20725023 0.492 ENSMUST00000020165.7
 Pde7b
phosphodiesterase 7B
chr1_+_137966529 0.460 ENSMUST00000182158.1
 A430106G13Rik
RIKEN cDNA A430106G13 gene
chr7_+_45897429 0.457 ENSMUST00000140243.1
 Tmem143
transmembrane protein 143
chr7_-_19715395 0.413 ENSMUST00000032555.9
ENSMUST00000093552.5
 Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr14_-_21848924 0.401 ENSMUST00000124549.1
 Comtd1
catechol-O-methyltransferase domain containing 1
chr7_-_79466167 0.387 ENSMUST00000073889.7
 Polg
polymerase (DNA directed), gamma
chr8_-_120668121 0.349 ENSMUST00000034277.7
 Emc8
ER membrane protein complex subunit 8
chr11_-_115267236 0.344 ENSMUST00000106554.1
 Grin2c
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr4_+_116075269 0.333 ENSMUST00000030471.8
 Lrrc41
leucine rich repeat containing 41
chr2_+_157279026 0.329 ENSMUST00000116380.2
 Rpn2
ribophorin II
chr12_-_84194007 0.309 ENSMUST00000110294.1
 Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr16_+_10545339 0.306 ENSMUST00000066345.7
ENSMUST00000115824.3
ENSMUST00000155633.1
 Clec16a


C-type lectin domain family 16, member A


chr11_-_4704334 0.301 ENSMUST00000058407.5
 Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr8_-_120668058 0.297 ENSMUST00000181950.1
ENSMUST00000181333.1
 Emc8
Gm27021
ER membrane protein complex subunit 8
predicted gene, 27021
chr2_+_157279065 0.294 ENSMUST00000029171.5
 Rpn2
ribophorin II
chr2_-_165283599 0.278 ENSMUST00000155289.1
 Slc35c2
solute carrier family 35, member C2
chr19_-_45998479 0.276 ENSMUST00000045396.7
 9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr8_+_120668222 0.264 ENSMUST00000034276.6
ENSMUST00000181586.1
 Cox4i1

cytochrome c oxidase subunit IV isoform 1

chr8_+_120668308 0.260 ENSMUST00000181795.1
 Cox4i1
cytochrome c oxidase subunit IV isoform 1
chr9_+_22003035 0.259 ENSMUST00000115331.2
ENSMUST00000003493.7
 Prkcsh

protein kinase C substrate 80K-H

chr15_+_79141324 0.259 ENSMUST00000040077.6
 Polr2f
polymerase (RNA) II (DNA directed) polypeptide F
chr16_-_4523056 0.257 ENSMUST00000090500.3
ENSMUST00000023161.7
 Srl

sarcalumenin

chrX_+_101299143 0.255 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
 Nlgn3


neuroligin 3


chr2_-_167492826 0.247 ENSMUST00000109211.2
ENSMUST00000057627.9
 Spata2

spermatogenesis associated 2

chr3_-_59210881 0.245 ENSMUST00000040622.1
 P2ry13
purinergic receptor P2Y, G-protein coupled 13
chr9_-_70141484 0.245 ENSMUST00000034749.8
 Fam81a
family with sequence similarity 81, member A
chr4_-_126202583 0.236 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
 Thrap3


thyroid hormone receptor associated protein 3


chr11_+_115475645 0.234 ENSMUST00000035240.6
 Armc7
armadillo repeat containing 7
chr6_+_91156772 0.230 ENSMUST00000143621.1
 Hdac11
histone deacetylase 11
chr9_-_22002599 0.211 ENSMUST00000115336.2
ENSMUST00000044926.5
 Ccdc151

coiled-coil domain containing 151

chr19_-_37207293 0.210 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
 Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr1_+_75435930 0.200 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
 Gmppa






GDP-mannose pyrophosphorylase A






chr4_+_43578921 0.198 ENSMUST00000030190.8
 Rgp1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr15_-_76918010 0.197 ENSMUST00000048854.7
 Zfp647
zinc finger protein 647
chr18_-_60624304 0.196 ENSMUST00000097566.3
 Synpo
synaptopodin
chr8_+_119862239 0.196 ENSMUST00000034287.8
 Klhl36
kelch-like 36
chr7_-_28598140 0.190 ENSMUST00000108283.1
ENSMUST00000040531.8
 Pak4
Samd4b
p21 protein (Cdc42/Rac)-activated kinase 4
sterile alpha motif domain containing 4B
chr4_+_134396320 0.178 ENSMUST00000105869.2
 Pafah2
platelet-activating factor acetylhydrolase 2
chr12_-_111672290 0.172 ENSMUST00000001304.7
 Ckb
creatine kinase, brain
chr2_+_92375306 0.169 ENSMUST00000028650.8
 Pex16
peroxisomal biogenesis factor 16
chrX_+_101299207 0.163 ENSMUST00000065858.2
 Nlgn3
neuroligin 3
chr17_-_35909626 0.160 ENSMUST00000141132.1
 Atat1
alpha tubulin acetyltransferase 1
chr11_-_3504766 0.158 ENSMUST00000044507.5
 Inpp5j
inositol polyphosphate 5-phosphatase J
chr6_-_113531575 0.149 ENSMUST00000032425.5
 Emc3
ER membrane protein complex subunit 3
chr6_+_41546730 0.145 ENSMUST00000103299.1
 Trbc2
T cell receptor beta, constant 2
chr4_-_150914401 0.138 ENSMUST00000105675.1
 Park7
Parkinson disease (autosomal recessive, early onset) 7
chr6_-_112946754 0.119 ENSMUST00000113169.2
 Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr7_-_126475082 0.113 ENSMUST00000032978.6
 Sh2b1
SH2B adaptor protein 1
chr2_-_180273488 0.111 ENSMUST00000108891.1
 Cables2
CDK5 and Abl enzyme substrate 2
chr2_+_79707780 0.100 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
 Ppp1r1c


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr15_-_79141197 0.099 ENSMUST00000169604.1
 1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr2_+_158794807 0.099 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
 Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr17_+_34605855 0.099 ENSMUST00000037489.8
 Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr11_+_90638127 0.087 ENSMUST00000020851.8
 Cox11
cytochrome c oxidase assembly protein 11
chr4_-_116075022 0.082 ENSMUST00000050580.4
ENSMUST00000078676.5
 Uqcrh

ubiquinol-cytochrome c reductase hinge protein

chr4_-_139131058 0.080 ENSMUST00000143971.1
 Minos1
mitochondrial inner membrane organizing system 1
chr6_+_91156665 0.067 ENSMUST00000041736.4
 Hdac11
histone deacetylase 11
chr2_-_163417092 0.063 ENSMUST00000127038.1
 Oser1
oxidative stress responsive serine rich 1
chr2_-_59160644 0.059 ENSMUST00000077687.5
 Ccdc148
coiled-coil domain containing 148
chr1_+_36691487 0.043 ENSMUST00000081180.4
 Cox5b
cytochrome c oxidase subunit Vb
chr6_+_91157373 0.042 ENSMUST00000155007.1
 Hdac11
histone deacetylase 11
chr13_-_73328442 0.041 ENSMUST00000022097.5
 Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr3_-_89213840 0.039 ENSMUST00000173477.1
ENSMUST00000119222.1
 Mtx1

metaxin 1

chr6_-_28421680 0.024 ENSMUST00000090511.3
 Gcc1
golgi coiled coil 1
chr2_-_33468493 0.018 ENSMUST00000113156.1
ENSMUST00000028125.5
ENSMUST00000126442.1
 Zbtb43


zinc finger and BTB domain containing 43


chr9_-_22085391 0.015 ENSMUST00000179422.1
ENSMUST00000098937.3
ENSMUST00000177967.1
ENSMUST00000180180.1
 Ecsit



ECSIT homolog (Drosophila)



chr4_+_126058557 0.006 ENSMUST00000035497.4
 Oscp1
organic solute carrier partner 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.6 4.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 4.0 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 0.7 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.4 GO:2000331 regulation of terminal button organization(GO:2000331)
0.1 1.0 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.7 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.1 1.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.8 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 0.2 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.3 GO:0015786 UDP-glucose transport(GO:0015786)
0.1 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 1.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.9 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 3.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0001964 startle response(GO:0001964)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0097444 spine apparatus(GO:0097444)
0.0 1.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 1.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 0.8 GO:0001847 opsonin receptor activity(GO:0001847)
0.2 1.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 0.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 5.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 5.2 PID_CDC42_PATHWAY CDC42 signaling events
0.0 1.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.7 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 5.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.9 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis