Motif ID: Obox1

Z-value: 0.735


Transcription factors associated with Obox1:

Gene SymbolEntrez IDGene Name
Obox1 ENSMUSG00000054310.10 Obox1



Activity profile for motif Obox1.

activity profile for motif Obox1


Sorted Z-values histogram for motif Obox1

Sorted Z-values for motif Obox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_53975246 7.135 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chr2_-_104257400 5.592 ENSMUST00000141159.1
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chr4_+_141368116 5.384 ENSMUST00000006380.4
 Fam131c
family with sequence similarity 131, member C
chr5_-_37717122 5.304 ENSMUST00000094836.4
 Stk32b
serine/threonine kinase 32B
chr4_+_74013442 4.785 ENSMUST00000098006.2
ENSMUST00000084474.5
 Frmd3

FERM domain containing 3

chr8_-_109251698 4.666 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr10_-_86732409 4.368 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chrX_-_165327376 4.277 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr6_+_58833689 4.242 ENSMUST00000041401.8
 Herc3
hect domain and RLD 3
chr11_+_70017199 4.186 ENSMUST00000133140.1
 Dlg4
discs, large homolog 4 (Drosophila)
chr15_-_84065329 3.903 ENSMUST00000156187.1
 Efcab6
EF-hand calcium binding domain 6
chr11_+_70017085 3.848 ENSMUST00000108589.2
 Dlg4
discs, large homolog 4 (Drosophila)
chr18_-_43393346 3.685 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr12_+_12262139 3.685 ENSMUST00000069066.6
ENSMUST00000069005.8
 Fam49a

family with sequence similarity 49, member A

chr7_-_134938264 3.296 ENSMUST00000171394.1
 Fam196a
family with sequence similarity 196, member A
chr16_+_31422268 3.146 ENSMUST00000089759.2
 Bdh1
3-hydroxybutyrate dehydrogenase, type 1
chrX_+_134295225 2.989 ENSMUST00000037687.7
 Tmem35
transmembrane protein 35
chr18_+_37489465 2.978 ENSMUST00000055949.2
 Pcdhb18
protocadherin beta 18
chr14_-_19977249 2.974 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr16_+_23290464 2.969 ENSMUST00000115335.1
 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 113 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 13.2 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 6.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 5.7 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.0 5.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.7 4.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 4.2 GO:0006869 lipid transport(GO:0006869)
0.0 4.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.2 4.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 3.5 GO:0008272 sulfate transport(GO:0008272)
0.1 3.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.2 3.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 3.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.7 3.0 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 3.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 2.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.9 2.7 GO:0015747 urate transport(GO:0015747)
0.7 2.7 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.4 2.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.4 2.7 GO:0032596 protein transport into membrane raft(GO:0032596)
0.3 2.7 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.4 8.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 7.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.7 GO:0005768 endosome(GO:0005768)
0.1 5.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.1 GO:0043204 perikaryon(GO:0043204)
0.4 3.5 GO:0002177 manchette(GO:0002177)
0.0 3.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.3 GO:0005770 late endosome(GO:0005770)
0.3 3.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 3.0 GO:0005811 lipid particle(GO:0005811)
0.7 2.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 2.5 GO:0044754 autolysosome(GO:0044754)
0.0 2.5 GO:0031941 filamentous actin(GO:0031941)
0.0 2.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 2.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.6 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.2 1.5 GO:0001739 sex chromatin(GO:0001739)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 8.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 7.4 GO:0043394 proteoglycan binding(GO:0043394)
0.4 7.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 6.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 5.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 4.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 4.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
1.4 4.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 4.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.4 3.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 3.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
1.0 3.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.6 3.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.4 2.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.9 2.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.7 2.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.7 2.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.7 2.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.2 ST_GA12_PATHWAY G alpha 12 Pathway
0.6 7.4 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 5.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.8 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 3.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 3.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.8 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.5 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 8.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 4.7 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 4.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 4.2 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.2 3.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.4 2.7 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 2.7 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.7 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 2.7 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 2.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 2.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.5 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.8 2.3 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.5 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.5 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.2 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism