Motif ID: Obox3

Z-value: 0.323


Transcription factors associated with Obox3:

Gene SymbolEntrez IDGene Name
Obox3 ENSMUSG00000066772.6 Obox3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Obox3mm10_v2_chr7_-_15627876_156278760.066.4e-01Click!


Activity profile for motif Obox3.

activity profile for motif Obox3


Sorted Z-values histogram for motif Obox3

Sorted Z-values for motif Obox3



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox3

PNG image of the network

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Top targets:


Showing 1 to 20 of 53 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_43393346 1.440 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr6_+_4902913 1.146 ENSMUST00000175889.1
ENSMUST00000168998.2
 Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr6_-_91807318 1.000 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr7_-_103843154 0.943 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr14_+_61138445 0.940 ENSMUST00000089394.3
ENSMUST00000119509.1
 Sacs

sacsin

chr4_+_74013442 0.937 ENSMUST00000098006.2
ENSMUST00000084474.5
 Frmd3

FERM domain containing 3

chr6_-_91807424 0.905 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr1_-_119836999 0.856 ENSMUST00000163621.1
ENSMUST00000168303.1
 Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr11_+_70459940 0.834 ENSMUST00000147289.1
ENSMUST00000126105.1
 Zmynd15

zinc finger, MYND-type containing 15

chr1_+_118389058 0.785 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
 Clasp1



CLIP associating protein 1



chr14_-_19977040 0.783 ENSMUST00000159028.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr14_-_19977249 0.783 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr1_+_178187721 0.757 ENSMUST00000159284.1
 Desi2
desumoylating isopeptidase 2
chr2_+_136892168 0.745 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chr14_-_19977151 0.740 ENSMUST00000055100.7
ENSMUST00000162425.1
 Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr19_+_3768112 0.599 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
 Suv420h1






suppressor of variegation 4-20 homolog 1 (Drosophila)






chr14_-_69805524 0.597 ENSMUST00000022665.2
 Rhobtb2
Rho-related BTB domain containing 2
chr7_+_35802593 0.581 ENSMUST00000052454.2
 E130304I02Rik
RIKEN cDNA E130304I02 gene
chr1_-_52232296 0.543 ENSMUST00000114512.1
 Gls
glutaminase
chr4_+_74242468 0.492 ENSMUST00000077851.3
 Kdm4c
lysine (K)-specific demethylase 4C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.9 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.4 1.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.9 GO:0015671 oxygen transport(GO:0015671)
0.1 0.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0033504 floor plate development(GO:0033504)
0.1 0.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.4 GO:0031941 filamentous actin(GO:0031941)
0.2 1.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.2 0.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.9 GO:0035254 glutamate receptor binding(GO:0035254)
0.2 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.9 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 0.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.7 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.3 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.7 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines