Motif ID: Olig2_Olig3
Z-value: 0.533
Transcription factors associated with Olig2_Olig3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Olig2 | ENSMUSG00000039830.8 | Olig2 |
Olig3 | ENSMUSG00000045591.5 | Olig3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Olig2 | mm10_v2_chr16_+_91225550_91225579 | -0.19 | 1.7e-01 | Click! |
Olig3 | mm10_v2_chr10_+_19356558_19356565 | 0.14 | 3.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 4.8 | GO:0098734 | protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734) |
0.7 | 2.1 | GO:0021759 | globus pallidus development(GO:0021759) |
0.5 | 1.6 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
0.5 | 1.6 | GO:0002159 | desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496) |
0.5 | 2.0 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
0.5 | 2.0 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.5 | 1.5 | GO:2000373 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
0.5 | 1.4 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.5 | 2.4 | GO:0015671 | oxygen transport(GO:0015671) |
0.4 | 1.8 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
0.4 | 1.5 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.4 | 2.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.3 | 1.4 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
0.3 | 1.0 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
0.3 | 1.6 | GO:0046950 | cellular ketone body metabolic process(GO:0046950) |
0.3 | 1.6 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
0.3 | 0.9 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
0.3 | 0.9 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.3 | 0.8 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) |
0.3 | 6.9 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
0.3 | 0.8 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.3 | 1.6 | GO:1904426 | positive regulation of GTP binding(GO:1904426) |
0.2 | 1.4 | GO:0032796 | uropod organization(GO:0032796) |
0.2 | 0.9 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.2 | 0.9 | GO:1902990 | leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
0.2 | 2.0 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.2 | 0.6 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
0.2 | 0.8 | GO:0006751 | glutathione catabolic process(GO:0006751) |
0.2 | 2.6 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
0.2 | 1.2 | GO:0003431 | growth plate cartilage chondrocyte development(GO:0003431) |
0.2 | 0.8 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
0.2 | 0.5 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
0.2 | 0.5 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
0.2 | 1.8 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
0.2 | 1.8 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.2 | 1.2 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
0.2 | 0.8 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
0.2 | 0.6 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
0.2 | 0.6 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
0.1 | 0.4 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.1 | 0.4 | GO:1904975 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
0.1 | 0.8 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.1 | 0.4 | GO:1902071 | positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
0.1 | 0.6 | GO:0090164 | asymmetric Golgi ribbon formation(GO:0090164) |
0.1 | 2.3 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.1 | 0.2 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
0.1 | 0.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.1 | 0.9 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
0.1 | 0.3 | GO:0032829 | tolerance induction to self antigen(GO:0002513) positive regulation of T cell anergy(GO:0002669) negative regulation of T cell cytokine production(GO:0002725) positive regulation of lymphocyte anergy(GO:0002913) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of transforming growth factor beta1 production(GO:0032914) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.1 | 0.6 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
0.1 | 0.3 | GO:1990859 | cellular response to endothelin(GO:1990859) |
0.1 | 1.6 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
0.1 | 0.5 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
0.1 | 0.3 | GO:0015866 | ADP transport(GO:0015866) |
0.1 | 0.6 | GO:0043654 | skeletal muscle satellite cell activation(GO:0014719) skeletal muscle satellite cell differentiation(GO:0014816) recognition of apoptotic cell(GO:0043654) |
0.1 | 0.5 | GO:1990928 | response to amino acid starvation(GO:1990928) |
0.1 | 2.8 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.1 | 0.3 | GO:0051030 | snRNA transport(GO:0051030) |
0.1 | 0.6 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.1 | 0.1 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
0.1 | 1.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.1 | 1.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
0.1 | 0.6 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.1 | 0.5 | GO:0061092 | bile acid secretion(GO:0032782) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
0.1 | 1.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.1 | 0.9 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 1.0 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.1 | 0.7 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.1 | 0.5 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
0.1 | 0.7 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
0.1 | 0.4 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
0.1 | 0.6 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
0.1 | 1.4 | GO:0048368 | lateral mesoderm development(GO:0048368) |
0.1 | 0.2 | GO:0097278 | transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278) |
0.1 | 0.2 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.1 | 0.4 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 0.4 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 0.8 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.2 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
0.0 | 0.2 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
0.0 | 0.2 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
0.0 | 1.2 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.0 | 0.4 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
0.0 | 2.7 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
0.0 | 0.2 | GO:1904690 | adenosine to inosine editing(GO:0006382) regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
0.0 | 0.5 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.3 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) |
0.0 | 0.7 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.0 | 0.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.6 | GO:0006517 | protein deglycosylation(GO:0006517) |
0.0 | 0.4 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
0.0 | 0.3 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.0 | 1.5 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
0.0 | 0.1 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.0 | 0.2 | GO:0007632 | visual behavior(GO:0007632) |
0.0 | 0.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.0 | 0.2 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.0 | 0.5 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 0.1 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
0.0 | 0.4 | GO:0046697 | decidualization(GO:0046697) |
0.0 | 0.3 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 1.7 | GO:0002066 | columnar/cuboidal epithelial cell development(GO:0002066) |
0.0 | 1.1 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
0.0 | 0.1 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
0.0 | 0.1 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.0 | 0.1 | GO:0009249 | protein lipoylation(GO:0009249) |
0.0 | 0.3 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.1 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.0 | 0.1 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.0 | 0.5 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 0.1 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.0 | 0.3 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 1.4 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 0.2 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.0 | 0.2 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.0 | 0.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.0 | 0.3 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 0.1 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.0 | 1.4 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.1 | GO:1903894 | regulation of IRE1-mediated unfolded protein response(GO:1903894) |
0.0 | 0.2 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
0.0 | 1.1 | GO:0050868 | negative regulation of T cell activation(GO:0050868) |
0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.0 | 0.5 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
0.0 | 0.2 | GO:0021924 | cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930) |
0.0 | 0.1 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.0 | 0.3 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
0.0 | 0.5 | GO:1902750 | negative regulation of cell cycle G2/M phase transition(GO:1902750) |
0.0 | 0.5 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
0.0 | 0.1 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
0.0 | 3.0 | GO:0016042 | lipid catabolic process(GO:0016042) |
0.0 | 0.4 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.0 | 0.1 | GO:0060324 | face development(GO:0060324) |
0.0 | 0.2 | GO:0001893 | maternal placenta development(GO:0001893) |
0.0 | 0.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.1 | GO:0030539 | male genitalia development(GO:0030539) |
0.0 | 0.2 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.0 | 0.2 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.0 | 2.0 | GO:0007612 | learning(GO:0007612) |
0.0 | 0.1 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 0.1 | GO:0070327 | thyroid hormone transport(GO:0070327) |
0.0 | 0.1 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
0.0 | 0.5 | GO:0032330 | regulation of chondrocyte differentiation(GO:0032330) |
0.0 | 0.2 | GO:0050667 | drug metabolic process(GO:0017144) homocysteine metabolic process(GO:0050667) |
0.0 | 0.1 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.0 | 0.3 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0044299 | C-fiber(GO:0044299) |
0.5 | 1.4 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
0.4 | 2.7 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.4 | 1.1 | GO:0034457 | Mpp10 complex(GO:0034457) |
0.3 | 0.9 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.3 | 2.4 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.3 | 1.6 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.3 | 1.1 | GO:0070552 | BRISC complex(GO:0070552) |
0.3 | 1.6 | GO:0030870 | Mre11 complex(GO:0030870) |
0.3 | 1.3 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.2 | 1.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.2 | 2.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.2 | 2.9 | GO:0030057 | desmosome(GO:0030057) |
0.2 | 0.6 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
0.2 | 1.6 | GO:0005775 | vacuolar lumen(GO:0005775) |
0.2 | 2.1 | GO:0005642 | annulate lamellae(GO:0005642) |
0.2 | 0.9 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.2 | 0.9 | GO:0097149 | centralspindlin complex(GO:0097149) |
0.1 | 0.4 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.1 | 0.6 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.1 | 1.4 | GO:0032426 | stereocilium tip(GO:0032426) |
0.1 | 7.7 | GO:0044295 | axonal growth cone(GO:0044295) |
0.1 | 0.6 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.1 | 0.8 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.1 | 1.5 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 0.3 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.1 | 0.2 | GO:0031417 | NatC complex(GO:0031417) |
0.1 | 1.2 | GO:0031105 | septin complex(GO:0031105) |
0.1 | 1.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 1.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.1 | 0.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 0.3 | GO:0033391 | chromatoid body(GO:0033391) |
0.1 | 0.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.1 | 1.4 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.1 | 0.7 | GO:0000974 | Prp19 complex(GO:0000974) |
0.1 | 0.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.0 | 2.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.0 | 0.2 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.0 | 0.5 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.2 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
0.0 | 0.7 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.0 | 0.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
0.0 | 0.3 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) |
0.0 | 0.5 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 0.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 1.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 1.1 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.3 | GO:0071664 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
0.0 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
0.0 | 0.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 1.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 1.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.6 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.2 | GO:0036157 | outer dynein arm(GO:0036157) |
0.0 | 0.2 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.0 | 1.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 1.5 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.0 | 0.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.5 | GO:0032040 | small-subunit processome(GO:0032040) |
0.0 | 0.9 | GO:0031201 | SNARE complex(GO:0031201) |
0.0 | 0.2 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.0 | 0.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.0 | 0.2 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 0.2 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.0 | GO:0044194 | cytolytic granule(GO:0044194) |
0.0 | 0.2 | GO:0031045 | dense core granule(GO:0031045) |
0.0 | 1.9 | GO:0043296 | apical junction complex(GO:0043296) |
0.0 | 0.1 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.0 | 0.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 0.0 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.4 | GO:0015030 | Cajal body(GO:0015030) |
0.0 | 0.2 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 0.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 5.0 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.5 | 1.4 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.5 | 4.8 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.5 | 2.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.5 | 1.4 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
0.4 | 1.8 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
0.4 | 2.0 | GO:0043532 | angiostatin binding(GO:0043532) |
0.4 | 1.6 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.4 | 2.0 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.4 | 1.1 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.3 | 1.0 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.3 | 2.3 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.3 | 0.9 | GO:0032139 | DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139) |
0.3 | 1.7 | GO:0008494 | translation activator activity(GO:0008494) |
0.3 | 0.8 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.3 | 0.8 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
0.2 | 0.7 | GO:0051870 | methotrexate binding(GO:0051870) |
0.2 | 2.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.2 | 0.9 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 2.6 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.2 | 1.5 | GO:0034046 | poly(G) binding(GO:0034046) |
0.2 | 0.6 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
0.2 | 0.6 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.1 | 0.5 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
0.1 | 2.1 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.1 | 0.5 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.1 | 1.4 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.1 | 1.6 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.1 | 0.4 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
0.1 | 0.5 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.1 | 0.8 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.1 | 0.6 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.1 | 0.2 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
0.1 | 0.4 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.1 | 0.5 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
0.1 | 0.5 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.1 | 1.6 | GO:0005537 | mannose binding(GO:0005537) |
0.1 | 0.4 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
0.1 | 0.5 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554) |
0.1 | 1.9 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.1 | 1.2 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
0.1 | 0.6 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.1 | 0.6 | GO:0000150 | recombinase activity(GO:0000150) |
0.1 | 0.6 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.2 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
0.1 | 1.4 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.1 | 0.2 | GO:0001729 | ceramide kinase activity(GO:0001729) |
0.1 | 0.2 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
0.1 | 0.2 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
0.1 | 1.0 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.1 | 0.7 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.1 | 0.4 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.1 | 0.3 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.1 | 0.6 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 0.9 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 0.3 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.1 | 0.8 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.1 | 1.1 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
0.0 | 0.6 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 1.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.0 | 0.5 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.0 | 0.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.0 | 0.7 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.0 | 0.3 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
0.0 | 0.7 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.5 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.3 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 0.6 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.0 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.0 | 2.5 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 0.3 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 0.5 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.0 | 0.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.3 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.9 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 0.9 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.2 | GO:0050815 | phosphoserine binding(GO:0050815) |
0.0 | 1.0 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.9 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.5 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
0.0 | 0.9 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
0.0 | 0.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 1.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.6 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.0 | 0.2 | GO:0042923 | neuropeptide binding(GO:0042923) |
0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
0.0 | 0.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.5 | GO:0052866 | phosphatidylinositol phosphate phosphatase activity(GO:0052866) |
0.0 | 0.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 2.0 | GO:0015399 | primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.0 | 0.4 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 1.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.0 | 2.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 1.1 | GO:0008026 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035) |
0.0 | 0.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.1 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
0.0 | 0.9 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.3 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 0.1 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
0.0 | 1.3 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.1 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) |
0.0 | 1.9 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.2 | GO:0015172 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
0.0 | 0.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.0 | 1.0 | GO:0004519 | endonuclease activity(GO:0004519) |
0.0 | 0.4 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
0.0 | 0.2 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 6.9 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 1.3 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.1 | 2.9 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.1 | 3.5 | PID_ATR_PATHWAY | ATR signaling pathway |
0.1 | 1.4 | PID_IL27_PATHWAY | IL27-mediated signaling events |
0.0 | 0.5 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
0.0 | 1.3 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.9 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.7 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 0.7 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 1.0 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 2.2 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.4 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 1.6 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 0.2 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.5 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.0 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.2 | 7.7 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.2 | 2.3 | REACTOME_POL_SWITCHING | Genes involved in Polymerase switching |
0.1 | 5.0 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.1 | 0.5 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.1 | 2.3 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.1 | 1.6 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.1 | 2.1 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.1 | 1.5 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.1 | 2.2 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.1 | 2.1 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 0.7 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.1 | 1.4 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 0.8 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 1.6 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | Genes involved in Activation of ATR in response to replication stress |
0.0 | 1.1 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.0 | 2.0 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
0.0 | 2.9 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.5 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.4 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 1.4 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.9 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 0.5 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.2 | REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
0.0 | 0.8 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.2 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.0 | 0.2 | REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
0.0 | 0.4 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.0 | 0.4 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.3 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.4 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.3 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 0.2 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.0 | 1.7 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 0.5 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 1.6 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |