Motif ID: Pax7

Z-value: 0.571


Transcription factors associated with Pax7:

Gene SymbolEntrez IDGene Name
Pax7 ENSMUSG00000028736.7 Pax7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax7mm10_v2_chr4_-_139833524_139833535-0.221.0e-01Click!


Activity profile for motif Pax7.

activity profile for motif Pax7


Sorted Z-values histogram for motif Pax7

Sorted Z-values for motif Pax7



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax7

PNG image of the network

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Top targets:


Showing 1 to 20 of 55 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_67113909 8.140 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr4_-_14621805 5.347 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr10_+_85386813 4.276 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr3_+_55461758 3.023 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr4_-_14621669 2.925 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr4_-_14621494 2.864 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr4_+_102589687 2.822 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr10_-_62379852 2.673 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
 Hk1



hexokinase 1



chr2_+_65620829 2.571 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr15_-_37459327 2.424 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chr15_-_64922290 2.234 ENSMUST00000023007.5
 Adcy8
adenylate cyclase 8
chr5_+_26817357 2.099 ENSMUST00000071500.6
 Dpp6
dipeptidylpeptidase 6
chr2_+_125136692 1.906 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr4_+_136286061 1.776 ENSMUST00000069195.4
ENSMUST00000130658.1
 Zfp46

zinc finger protein 46

chr11_-_115276973 1.641 ENSMUST00000021078.2
 Fdxr
ferredoxin reductase
chr4_+_108719649 1.542 ENSMUST00000178992.1
 3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr5_-_92348871 1.499 ENSMUST00000038816.6
ENSMUST00000118006.1
 Cxcl10

chemokine (C-X-C motif) ligand 10

chr1_+_72284367 1.393 ENSMUST00000027380.5
ENSMUST00000141783.1
 Tmem169

transmembrane protein 169

chr8_-_34965631 1.353 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr19_+_8802486 1.304 ENSMUST00000172175.1
 Zbtb3
zinc finger and BTB domain containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 11.1 GO:0019532 oxalate transport(GO:0019532)
0.2 8.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 4.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 3.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 2.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 2.7 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 2.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.1 2.2 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 2.1 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 1.6 GO:0070995 NADPH oxidation(GO:0070995)
0.5 1.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.5 1.4 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.3 1.0 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.6 GO:0015791 polyol transport(GO:0015791) bile acid secretion(GO:0032782)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.3 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 8.1 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 2.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.0 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 11.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
2.0 8.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 4.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 2.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.5 2.7 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 2.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 2.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 2.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.6 GO:0070402 NADPH binding(GO:0070402)
0.3 1.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 0.6 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.2 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.2 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 1.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.8 8.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 2.7 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.1 2.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 0.8 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.6 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA