Motif ID: Phox2a

Z-value: 0.488


Transcription factors associated with Phox2a:

Gene SymbolEntrez IDGene Name
Phox2a ENSMUSG00000007946.9 Phox2a



Activity profile for motif Phox2a.

activity profile for motif Phox2a


Sorted Z-values histogram for motif Phox2a

Sorted Z-values for motif Phox2a



Network of associatons between targets according to the STRING database.



First level regulatory network of Phox2a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_60893430 4.649 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr2_+_20737306 3.955 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr4_-_14621805 3.065 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr2_-_168767136 2.552 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr2_-_168767029 2.549 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr4_-_14621669 2.065 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr4_-_14621494 1.947 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr13_-_102906046 1.584 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr9_+_119063429 1.556 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr15_-_67113909 1.474 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr13_-_102905740 1.470 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr16_-_42340595 0.783 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr6_-_147264124 0.566 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr19_-_41933276 0.438 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr7_-_38019505 0.368 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr8_-_84662841 0.349 ENSMUST00000060427.4
Ier2
immediate early response 2
chrX_-_139871637 0.340 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr1_-_89933290 0.335 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr19_+_41933464 0.287 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr5_-_34660068 0.236 ENSMUST00000041364.9
Nop14
NOP14 nucleolar protein
chr14_+_4198185 0.231 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr1_-_172027269 0.205 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr4_+_134930898 0.142 ENSMUST00000030622.2
Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)
chr14_-_5863663 0.136 ENSMUST00000178594.1
Gm8237
predicted gene 8237
chr2_+_36230426 0.068 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr11_+_116843278 0.064 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr8_+_107031218 0.031 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.1 GO:0019532 oxalate transport(GO:0019532)
0.3 5.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 4.6 GO:0007530 sex determination(GO:0007530)
0.1 0.6 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.8 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 1.6 GO:0051693 actin filament capping(GO:0051693)
0.0 1.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 4.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.0 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0030689 Noc complex(GO:0030689)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 5.1 GO:0000792 heterochromatin(GO:0000792)
0.0 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 7.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.4 1.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 5.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 3.1 GO:0000287 magnesium ion binding(GO:0000287)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 5.1 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.4 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 7.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease