Motif ID: Pitx2_Otx2
Z-value: 1.599
Transcription factors associated with Pitx2_Otx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Otx2 | ENSMUSG00000021848.9 | Otx2 |
Pitx2 | ENSMUSG00000028023.10 | Pitx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Otx2 | mm10_v2_chr14_-_48665098_48665246 | 0.60 | 1.1e-06 | Click! |
Pitx2 | mm10_v2_chr3_+_129213920_129213938 | 0.36 | 7.5e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 12.2 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356) |
4.0 | 12.1 | GO:0042732 | D-xylose metabolic process(GO:0042732) |
3.1 | 9.2 | GO:0021557 | oculomotor nerve development(GO:0021557) |
2.7 | 8.2 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
2.7 | 13.3 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
2.3 | 9.0 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
2.2 | 6.7 | GO:1904975 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
2.1 | 6.3 | GO:1990523 | bone regeneration(GO:1990523) |
1.9 | 5.6 | GO:0002865 | immune response-inhibiting signal transduction(GO:0002765) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) |
1.9 | 18.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
1.8 | 5.3 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
1.8 | 5.3 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
1.8 | 5.3 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
1.7 | 5.2 | GO:0045004 | DNA replication proofreading(GO:0045004) |
1.7 | 6.8 | GO:0015825 | L-serine transport(GO:0015825) |
1.7 | 5.0 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
1.6 | 4.8 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
1.5 | 4.5 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
1.5 | 6.0 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
1.4 | 7.1 | GO:0015705 | iodide transport(GO:0015705) |
1.4 | 6.9 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
1.3 | 5.3 | GO:0045950 | negative regulation of mitotic recombination(GO:0045950) |
1.3 | 5.2 | GO:1902990 | mitotic telomere maintenance via semi-conservative replication(GO:1902990) |
1.2 | 3.7 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
1.2 | 6.1 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
1.2 | 1.2 | GO:0071726 | response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) |
1.2 | 7.0 | GO:0003383 | apical constriction(GO:0003383) |
1.1 | 6.8 | GO:0046502 | uroporphyrinogen III metabolic process(GO:0046502) |
1.1 | 4.5 | GO:0033087 | negative regulation of immature T cell proliferation(GO:0033087) |
1.1 | 5.6 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
1.1 | 3.3 | GO:0016095 | polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310) |
1.1 | 3.2 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
1.1 | 3.2 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
1.1 | 7.4 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
1.0 | 3.1 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
1.0 | 3.1 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
1.0 | 24.0 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
1.0 | 3.0 | GO:0036292 | DNA rewinding(GO:0036292) |
1.0 | 3.0 | GO:0050787 | glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) |
1.0 | 8.9 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
1.0 | 1.9 | GO:1902071 | regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
1.0 | 9.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.9 | 3.7 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
0.9 | 2.8 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
0.9 | 8.3 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.9 | 2.6 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.9 | 3.5 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
0.8 | 2.5 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166) |
0.8 | 4.0 | GO:0019244 | lactate biosynthetic process from pyruvate(GO:0019244) |
0.8 | 4.7 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.8 | 2.3 | GO:0015920 | regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920) |
0.7 | 3.7 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.7 | 3.0 | GO:1903519 | apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
0.7 | 0.7 | GO:0014016 | neuroblast differentiation(GO:0014016) |
0.7 | 3.7 | GO:0019236 | response to pheromone(GO:0019236) |
0.7 | 2.9 | GO:0046210 | nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346) |
0.7 | 2.1 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.7 | 2.6 | GO:0006203 | dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061) |
0.6 | 1.9 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
0.6 | 1.9 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
0.6 | 1.9 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
0.6 | 5.7 | GO:0033504 | floor plate development(GO:0033504) |
0.6 | 3.1 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.6 | 6.9 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
0.6 | 2.4 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.6 | 1.8 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.6 | 3.5 | GO:0048318 | axial mesoderm development(GO:0048318) |
0.6 | 2.3 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
0.6 | 4.0 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.6 | 4.0 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
0.6 | 1.7 | GO:0007525 | somatic muscle development(GO:0007525) |
0.6 | 1.1 | GO:0006566 | threonine metabolic process(GO:0006566) |
0.5 | 19.0 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.5 | 2.2 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
0.5 | 2.1 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.5 | 1.6 | GO:2000409 | positive regulation of T cell extravasation(GO:2000409) |
0.5 | 1.0 | GO:0090202 | transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579) |
0.5 | 4.1 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
0.5 | 3.1 | GO:0032229 | negative regulation of synaptic transmission, GABAergic(GO:0032229) |
0.5 | 2.5 | GO:0019614 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
0.5 | 3.5 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.5 | 2.0 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.5 | 2.9 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
0.5 | 5.8 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.5 | 3.8 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.5 | 1.4 | GO:1901355 | response to rapamycin(GO:1901355) |
0.5 | 3.3 | GO:0042148 | strand invasion(GO:0042148) |
0.4 | 2.6 | GO:0086028 | bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) |
0.4 | 1.3 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
0.4 | 1.3 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
0.4 | 2.5 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
0.4 | 2.0 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
0.4 | 4.0 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
0.4 | 1.6 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
0.4 | 2.8 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.4 | 3.1 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) |
0.4 | 1.2 | GO:0016598 | protein arginylation(GO:0016598) |
0.4 | 1.2 | GO:1904719 | excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
0.4 | 3.5 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
0.4 | 11.2 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.4 | 1.9 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
0.4 | 1.9 | GO:0090666 | telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666) |
0.4 | 3.7 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
0.4 | 2.6 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
0.4 | 1.9 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
0.4 | 1.5 | GO:0097694 | leptotene(GO:0000237) establishment of RNA localization to telomere(GO:0097694) |
0.4 | 1.5 | GO:0030043 | actin filament fragmentation(GO:0030043) |
0.4 | 1.1 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.4 | 1.1 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
0.4 | 2.9 | GO:0051024 | positive regulation of immunoglobulin secretion(GO:0051024) |
0.4 | 3.9 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.4 | 0.7 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
0.4 | 1.1 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
0.4 | 1.8 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.3 | 1.4 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.3 | 5.1 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.3 | 1.0 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.3 | 1.6 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.3 | 2.0 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.3 | 0.3 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
0.3 | 0.9 | GO:0021972 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
0.3 | 3.5 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.3 | 1.6 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.3 | 1.6 | GO:0015822 | ornithine transport(GO:0015822) |
0.3 | 4.1 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.3 | 2.8 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
0.3 | 3.4 | GO:0070836 | caveola assembly(GO:0070836) |
0.3 | 1.9 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
0.3 | 11.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.3 | 2.7 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
0.3 | 2.1 | GO:0031424 | keratinization(GO:0031424) |
0.3 | 1.2 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
0.3 | 1.7 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
0.3 | 1.4 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.3 | 2.9 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
0.3 | 1.7 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
0.3 | 2.5 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
0.3 | 2.8 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.3 | 1.1 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
0.3 | 1.3 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.3 | 0.8 | GO:0036166 | phenotypic switching(GO:0036166) |
0.3 | 1.6 | GO:0036337 | Fas signaling pathway(GO:0036337) |
0.3 | 1.6 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.3 | 1.8 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
0.3 | 1.3 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
0.3 | 4.1 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
0.3 | 1.0 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.3 | 1.3 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.3 | 1.0 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.3 | 0.8 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
0.3 | 1.8 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
0.3 | 1.0 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
0.3 | 1.5 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
0.3 | 1.3 | GO:0030423 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) |
0.3 | 0.8 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
0.2 | 10.9 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.2 | 8.3 | GO:0016572 | histone phosphorylation(GO:0016572) |
0.2 | 0.7 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.2 | 7.2 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.2 | 3.1 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.2 | 1.2 | GO:0010831 | positive regulation of myotube differentiation(GO:0010831) |
0.2 | 4.5 | GO:0031297 | replication fork processing(GO:0031297) |
0.2 | 1.4 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.2 | 1.1 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.2 | 5.7 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.2 | 0.5 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
0.2 | 1.4 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.2 | 1.1 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.2 | 3.2 | GO:0003334 | keratinocyte development(GO:0003334) |
0.2 | 0.9 | GO:0002339 | B cell selection(GO:0002339) |
0.2 | 0.9 | GO:0015817 | histidine transport(GO:0015817) |
0.2 | 4.3 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.2 | 1.3 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
0.2 | 2.2 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.2 | 1.1 | GO:1905155 | apolipoprotein A-I-mediated signaling pathway(GO:0038027) positive regulation of phagocytosis, engulfment(GO:0060100) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of membrane invagination(GO:1905155) |
0.2 | 2.4 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.2 | 2.4 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.2 | 4.5 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.2 | 1.5 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
0.2 | 5.4 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.2 | 0.9 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
0.2 | 3.2 | GO:0006085 | acetyl-CoA biosynthetic process(GO:0006085) |
0.2 | 6.0 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.2 | 6.2 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.2 | 1.4 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
0.2 | 1.8 | GO:0070475 | rRNA base methylation(GO:0070475) |
0.2 | 2.8 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.2 | 2.0 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.2 | 1.2 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
0.2 | 0.6 | GO:0036506 | maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.2 | 0.6 | GO:0036233 | glycine import(GO:0036233) |
0.2 | 3.8 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.2 | 1.7 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.2 | 3.4 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.2 | 1.5 | GO:0008343 | adult feeding behavior(GO:0008343) |
0.2 | 1.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.2 | 0.4 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
0.2 | 2.0 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.2 | 0.4 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.2 | 0.9 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
0.2 | 0.4 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
0.2 | 0.4 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
0.2 | 2.7 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.2 | 1.6 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
0.2 | 0.9 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
0.2 | 3.9 | GO:0045760 | positive regulation of action potential(GO:0045760) |
0.2 | 0.7 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.2 | 0.7 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
0.2 | 3.9 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.2 | 2.7 | GO:0030903 | notochord development(GO:0030903) |
0.2 | 0.7 | GO:0030576 | Cajal body organization(GO:0030576) |
0.2 | 1.1 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
0.2 | 2.3 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
0.2 | 3.3 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
0.2 | 1.7 | GO:1903894 | regulation of IRE1-mediated unfolded protein response(GO:1903894) |
0.2 | 5.1 | GO:0006739 | NADP metabolic process(GO:0006739) |
0.2 | 0.9 | GO:0071494 | cellular response to UV-C(GO:0071494) |
0.2 | 1.2 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.1 | 0.7 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
0.1 | 7.7 | GO:0009060 | aerobic respiration(GO:0009060) |
0.1 | 1.9 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.1 | 0.7 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.1 | 1.5 | GO:1990403 | embryonic brain development(GO:1990403) |
0.1 | 0.3 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
0.1 | 11.1 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
0.1 | 1.0 | GO:0055070 | copper ion homeostasis(GO:0055070) |
0.1 | 2.1 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.1 | 0.8 | GO:1901836 | regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) |
0.1 | 1.2 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.1 | 0.8 | GO:0036006 | response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006) |
0.1 | 1.8 | GO:0042407 | cristae formation(GO:0042407) |
0.1 | 1.5 | GO:0036035 | osteoclast development(GO:0036035) |
0.1 | 2.2 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.1 | 8.3 | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) |
0.1 | 0.9 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
0.1 | 1.6 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
0.1 | 3.2 | GO:0006825 | copper ion transport(GO:0006825) |
0.1 | 3.3 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
0.1 | 1.2 | GO:0060347 | heart trabecula formation(GO:0060347) amyloid fibril formation(GO:1990000) |
0.1 | 0.3 | GO:0031622 | positive regulation of fever generation(GO:0031622) |
0.1 | 1.0 | GO:0045023 | G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317) |
0.1 | 1.0 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 16.8 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
0.1 | 5.0 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.1 | 0.7 | GO:2000096 | regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.1 | 2.4 | GO:0001779 | natural killer cell differentiation(GO:0001779) |
0.1 | 3.3 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.1 | 1.6 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.1 | 1.3 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.1 | 1.6 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.1 | 7.5 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.1 | 0.2 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.1 | 0.3 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
0.1 | 0.9 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
0.1 | 1.9 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.1 | 4.7 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
0.1 | 0.3 | GO:0015960 | diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) |
0.1 | 1.3 | GO:0043248 | proteasome assembly(GO:0043248) |
0.1 | 2.0 | GO:0046686 | response to cadmium ion(GO:0046686) |
0.1 | 1.3 | GO:0060325 | head morphogenesis(GO:0060323) face morphogenesis(GO:0060325) |
0.1 | 5.3 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.1 | 1.6 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.1 | 0.3 | GO:1904046 | seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046) |
0.1 | 4.1 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.1 | 0.4 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
0.1 | 0.6 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.1 | 2.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.1 | 1.2 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.1 | 0.6 | GO:0030223 | neutrophil differentiation(GO:0030223) |
0.1 | 0.1 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
0.1 | 1.5 | GO:0006582 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
0.1 | 1.0 | GO:0000963 | mitochondrial RNA processing(GO:0000963) |
0.1 | 0.7 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.1 | 1.2 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
0.1 | 0.9 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
0.1 | 11.1 | GO:0031109 | microtubule polymerization or depolymerization(GO:0031109) |
0.1 | 1.5 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.1 | 5.1 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.1 | 0.3 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) positive regulation of DNA-templated transcription, elongation(GO:0032786) positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
0.1 | 1.3 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
0.1 | 0.2 | GO:0072526 | pyridine-containing compound catabolic process(GO:0072526) |
0.1 | 1.0 | GO:0051601 | exocyst localization(GO:0051601) |
0.1 | 1.4 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
0.1 | 0.8 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.1 | 0.4 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.1 | 0.4 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.1 | 0.4 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.1 | 0.2 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) |
0.1 | 2.1 | GO:1903427 | negative regulation of reactive oxygen species biosynthetic process(GO:1903427) |
0.1 | 0.2 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 1.2 | GO:0007398 | ectoderm development(GO:0007398) |
0.1 | 0.5 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
0.1 | 1.0 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
0.1 | 0.2 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
0.1 | 0.6 | GO:0021554 | optic nerve development(GO:0021554) |
0.1 | 0.5 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.1 | 1.0 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.1 | 0.5 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.1 | 0.5 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
0.1 | 3.3 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.1 | 1.3 | GO:0006625 | protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
0.1 | 0.7 | GO:0035413 | positive regulation of catenin import into nucleus(GO:0035413) |
0.1 | 1.7 | GO:0001702 | gastrulation with mouth forming second(GO:0001702) |
0.1 | 0.9 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.1 | 1.6 | GO:0016180 | snRNA processing(GO:0016180) |
0.1 | 2.3 | GO:0016445 | somatic diversification of immunoglobulins(GO:0016445) |
0.1 | 0.4 | GO:0090383 | phagosome acidification(GO:0090383) |
0.1 | 3.0 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.1 | 2.2 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.1 | 1.7 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
0.1 | 1.0 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.1 | 0.8 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
0.1 | 1.5 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.1 | 0.7 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
0.1 | 0.6 | GO:0001675 | acrosome assembly(GO:0001675) |
0.1 | 0.7 | GO:1902083 | cellular response to hydroperoxide(GO:0071447) negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.1 | 1.7 | GO:0033522 | histone H2A ubiquitination(GO:0033522) |
0.1 | 0.1 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
0.1 | 2.8 | GO:0016925 | protein sumoylation(GO:0016925) |
0.1 | 0.3 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
0.1 | 0.6 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.1 | 1.3 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.1 | 0.8 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
0.1 | 0.4 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.1 | 0.5 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.1 | 2.2 | GO:0048709 | oligodendrocyte differentiation(GO:0048709) |
0.1 | 0.2 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
0.1 | 0.2 | GO:0006788 | heme oxidation(GO:0006788) |
0.1 | 0.5 | GO:0016926 | protein desumoylation(GO:0016926) |
0.1 | 0.4 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 0.2 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
0.0 | 1.1 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.8 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.3 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 1.7 | GO:0051881 | regulation of mitochondrial membrane potential(GO:0051881) |
0.0 | 0.3 | GO:0070474 | regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474) |
0.0 | 2.7 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 0.1 | GO:0090343 | positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774) |
0.0 | 1.2 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.3 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
0.0 | 0.3 | GO:0016139 | glycoside catabolic process(GO:0016139) |
0.0 | 0.2 | GO:0044068 | modulation by symbiont of host cellular process(GO:0044068) |
0.0 | 1.2 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.2 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
0.0 | 0.1 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
0.0 | 1.6 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
0.0 | 0.9 | GO:1901796 | regulation of signal transduction by p53 class mediator(GO:1901796) |
0.0 | 0.2 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.0 | 1.5 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 1.1 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
0.0 | 0.2 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) actin filament severing(GO:0051014) negative regulation of actin nucleation(GO:0051126) |
0.0 | 0.7 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.3 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 0.2 | GO:0060149 | negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) |
0.0 | 0.9 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
0.0 | 0.3 | GO:0071353 | response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353) |
0.0 | 0.1 | GO:1901185 | negative regulation of ERBB signaling pathway(GO:1901185) |
0.0 | 0.3 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
0.0 | 0.3 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.0 | 1.0 | GO:0007566 | embryo implantation(GO:0007566) |
0.0 | 0.1 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.0 | 0.2 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
0.0 | 1.2 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.0 | 0.4 | GO:0052548 | regulation of endopeptidase activity(GO:0052548) |
0.0 | 0.2 | GO:0017144 | drug metabolic process(GO:0017144) |
0.0 | 0.1 | GO:0019321 | pentose metabolic process(GO:0019321) |
0.0 | 0.3 | GO:0036037 | CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.2 | GO:0002507 | tolerance induction(GO:0002507) |
0.0 | 0.1 | GO:0032988 | ribonucleoprotein complex disassembly(GO:0032988) |
0.0 | 0.7 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.0 | 1.2 | GO:0006405 | RNA export from nucleus(GO:0006405) |
0.0 | 0.2 | GO:0045333 | cellular respiration(GO:0045333) |
0.0 | 1.3 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.2 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.2 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.0 | 0.3 | GO:0043039 | tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039) |
0.0 | 0.3 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
0.0 | 0.5 | GO:0045580 | regulation of T cell differentiation(GO:0045580) |
0.0 | 0.6 | GO:0007098 | centrosome cycle(GO:0007098) |
0.0 | 0.0 | GO:0006702 | androgen biosynthetic process(GO:0006702) |
0.0 | 0.3 | GO:0043966 | histone H3 acetylation(GO:0043966) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.7 | 21.3 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
2.0 | 14.1 | GO:0001940 | male pronucleus(GO:0001940) |
1.9 | 5.8 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
1.6 | 6.2 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
1.4 | 4.3 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
1.3 | 7.9 | GO:1990393 | 3M complex(GO:1990393) |
1.3 | 5.1 | GO:0032021 | NELF complex(GO:0032021) |
1.2 | 6.2 | GO:0044316 | cone cell pedicle(GO:0044316) |
1.2 | 19.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
1.1 | 3.2 | GO:0035101 | FACT complex(GO:0035101) |
1.1 | 3.2 | GO:0071914 | prominosome(GO:0071914) |
1.0 | 5.2 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
1.0 | 3.1 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
1.0 | 5.1 | GO:0000235 | astral microtubule(GO:0000235) |
1.0 | 6.0 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
1.0 | 16.7 | GO:0005652 | nuclear lamina(GO:0005652) |
1.0 | 3.9 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
0.9 | 2.8 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
0.9 | 8.3 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
0.9 | 4.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.9 | 7.0 | GO:0033269 | internode region of axon(GO:0033269) |
0.8 | 2.4 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.8 | 3.2 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
0.8 | 3.0 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
0.7 | 5.6 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.7 | 9.1 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.7 | 2.1 | GO:1990047 | spindle matrix(GO:1990047) |
0.7 | 1.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.7 | 3.3 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.6 | 2.5 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.6 | 1.9 | GO:0000811 | GINS complex(GO:0000811) |
0.6 | 6.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.6 | 1.8 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.6 | 3.5 | GO:0033010 | paranodal junction(GO:0033010) |
0.5 | 2.1 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
0.5 | 6.7 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.5 | 3.1 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.5 | 1.5 | GO:0000801 | central element(GO:0000801) |
0.5 | 5.3 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.5 | 35.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.5 | 5.6 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.5 | 1.9 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
0.5 | 6.9 | GO:0031105 | septin complex(GO:0031105) |
0.4 | 1.8 | GO:0070552 | BRISC complex(GO:0070552) |
0.4 | 4.0 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.4 | 4.8 | GO:0005688 | U6 snRNP(GO:0005688) |
0.4 | 1.7 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
0.4 | 5.9 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.4 | 5.8 | GO:0000974 | Prp19 complex(GO:0000974) |
0.4 | 5.0 | GO:0031528 | microvillus membrane(GO:0031528) |
0.4 | 2.1 | GO:0001533 | cornified envelope(GO:0001533) |
0.4 | 3.7 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.4 | 21.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.4 | 1.6 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.4 | 1.6 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.4 | 1.6 | GO:0005745 | m-AAA complex(GO:0005745) |
0.4 | 8.9 | GO:0031527 | filopodium membrane(GO:0031527) |
0.4 | 1.2 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
0.3 | 2.0 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.3 | 2.7 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.3 | 2.5 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
0.3 | 3.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.3 | 1.8 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.3 | 16.0 | GO:0005871 | kinesin complex(GO:0005871) |
0.3 | 23.6 | GO:0005643 | nuclear pore(GO:0005643) |
0.3 | 1.6 | GO:0005796 | Golgi lumen(GO:0005796) |
0.3 | 1.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.3 | 1.3 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.3 | 1.6 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.3 | 0.8 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
0.3 | 3.0 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.2 | 2.8 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.2 | 16.8 | GO:0070469 | respiratory chain(GO:0070469) |
0.2 | 2.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.2 | 3.0 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.2 | 1.5 | GO:0070187 | telosome(GO:0070187) |
0.2 | 1.0 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.2 | 1.2 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.2 | 1.8 | GO:0061617 | MICOS complex(GO:0061617) |
0.2 | 0.9 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
0.2 | 0.9 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.2 | 7.1 | GO:0034707 | chloride channel complex(GO:0034707) |
0.2 | 4.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.2 | 1.5 | GO:0036157 | outer dynein arm(GO:0036157) |
0.2 | 1.4 | GO:0031415 | NatA complex(GO:0031415) |
0.2 | 1.6 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.2 | 1.3 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
0.2 | 3.2 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.2 | 1.9 | GO:0042555 | MCM complex(GO:0042555) |
0.2 | 0.8 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
0.2 | 2.5 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.1 | 2.0 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 1.0 | GO:0022626 | cytosolic ribosome(GO:0022626) |
0.1 | 5.3 | GO:1990204 | oxidoreductase complex(GO:1990204) |
0.1 | 3.7 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.1 | 1.8 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 2.8 | GO:0005686 | U2 snRNP(GO:0005686) |
0.1 | 6.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 1.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.1 | 6.2 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 11.7 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
0.1 | 1.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.1 | 2.3 | GO:0043596 | nuclear replication fork(GO:0043596) |
0.1 | 2.7 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.1 | 1.6 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 1.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 2.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.1 | 10.6 | GO:0016363 | nuclear matrix(GO:0016363) |
0.1 | 0.6 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.1 | 6.5 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.1 | 0.9 | GO:0070652 | HAUS complex(GO:0070652) |
0.1 | 1.1 | GO:0046930 | pore complex(GO:0046930) |
0.1 | 1.2 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.1 | 1.9 | GO:0071564 | npBAF complex(GO:0071564) |
0.1 | 1.9 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.1 | 1.0 | GO:0000812 | Swr1 complex(GO:0000812) |
0.1 | 4.2 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.1 | 7.1 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 0.6 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 0.4 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.1 | 0.9 | GO:0043218 | compact myelin(GO:0043218) |
0.1 | 5.5 | GO:0016459 | myosin complex(GO:0016459) |
0.1 | 1.1 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.1 | 1.4 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.1 | 1.1 | GO:0090544 | BAF-type complex(GO:0090544) |
0.1 | 4.2 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.1 | 1.0 | GO:0035770 | ribonucleoprotein granule(GO:0035770) |
0.1 | 1.0 | GO:0000145 | exocyst(GO:0000145) |
0.1 | 0.9 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.1 | 0.6 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.1 | 1.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.1 | 5.7 | GO:0005811 | lipid particle(GO:0005811) |
0.1 | 5.1 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.1 | 0.5 | GO:0090543 | Flemming body(GO:0090543) |
0.1 | 0.5 | GO:0070847 | core mediator complex(GO:0070847) |
0.1 | 1.9 | GO:0030904 | retromer complex(GO:0030904) |
0.1 | 1.5 | GO:0030914 | STAGA complex(GO:0030914) |
0.1 | 3.2 | GO:0005902 | microvillus(GO:0005902) |
0.1 | 0.7 | GO:0016272 | prefoldin complex(GO:0016272) |
0.1 | 1.5 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 23.3 | GO:0016607 | nuclear speck(GO:0016607) |
0.1 | 7.2 | GO:0000776 | kinetochore(GO:0000776) |
0.1 | 6.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 0.6 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.1 | 2.0 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.1 | 0.9 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 7.0 | GO:0005903 | brush border(GO:0005903) |
0.1 | 0.3 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.1 | 2.0 | GO:0097546 | ciliary base(GO:0097546) |
0.1 | 0.4 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.1 | 10.8 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 5.0 | GO:0005814 | centriole(GO:0005814) |
0.1 | 5.9 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.1 | 0.2 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
0.1 | 1.2 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 0.9 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.1 | 1.2 | GO:0030286 | dynein complex(GO:0030286) |
0.1 | 0.4 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.1 | 1.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.1 | 0.1 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.1 | 1.1 | GO:0001891 | phagocytic cup(GO:0001891) |
0.1 | 3.3 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.1 | 1.8 | GO:0005840 | ribosome(GO:0005840) |
0.1 | 1.1 | GO:0030686 | 90S preribosome(GO:0030686) |
0.1 | 1.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.1 | 0.9 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.7 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 1.8 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 5.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 2.1 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.6 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 2.6 | GO:0014704 | intercalated disc(GO:0014704) |
0.0 | 0.6 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.0 | 0.2 | GO:0030891 | VCB complex(GO:0030891) |
0.0 | 0.5 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 10.1 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 0.8 | GO:0002102 | podosome(GO:0002102) |
0.0 | 1.1 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.3 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 0.3 | GO:0031011 | Ino80 complex(GO:0031011) INO80-type complex(GO:0097346) |
0.0 | 0.4 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.5 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 1.4 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.3 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 1.0 | GO:0036126 | sperm flagellum(GO:0036126) |
0.0 | 0.6 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.7 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
0.0 | 0.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.2 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 4.1 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 0.2 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.3 | GO:0032590 | dendrite membrane(GO:0032590) |
0.0 | 0.4 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 0.1 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.0 | GO:0070852 | cell body fiber(GO:0070852) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 12.2 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
3.0 | 9.0 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
2.8 | 14.2 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
2.1 | 6.2 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
1.8 | 7.1 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
1.7 | 5.2 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
1.7 | 5.2 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
1.5 | 4.6 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
1.3 | 18.6 | GO:0003688 | DNA replication origin binding(GO:0003688) |
1.2 | 18.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
1.2 | 3.5 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
1.1 | 4.4 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
1.1 | 3.3 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
1.1 | 4.4 | GO:0016842 | amidine-lyase activity(GO:0016842) |
1.1 | 5.4 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
1.1 | 4.3 | GO:0050436 | microfibril binding(GO:0050436) |
1.1 | 3.2 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
1.0 | 8.4 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
1.0 | 3.1 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
1.0 | 4.0 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
1.0 | 4.0 | GO:0003998 | acylphosphatase activity(GO:0003998) |
1.0 | 4.0 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
1.0 | 3.0 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
1.0 | 5.7 | GO:0042731 | PH domain binding(GO:0042731) |
1.0 | 3.8 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
0.9 | 3.7 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
0.9 | 5.6 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
0.9 | 3.7 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.9 | 4.6 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.9 | 2.7 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
0.9 | 5.3 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.9 | 2.6 | GO:0098770 | FBXO family protein binding(GO:0098770) |
0.9 | 9.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.8 | 2.5 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.8 | 4.2 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
0.8 | 3.3 | GO:0035877 | death effector domain binding(GO:0035877) |
0.8 | 4.0 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
0.8 | 2.3 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.8 | 22.9 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.8 | 8.3 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.7 | 10.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.7 | 5.1 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
0.7 | 12.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.7 | 5.8 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.7 | 2.9 | GO:0016708 | nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726) |
0.7 | 3.6 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.7 | 2.1 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
0.7 | 0.7 | GO:0005402 | cation:sugar symporter activity(GO:0005402) |
0.7 | 3.3 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.7 | 2.6 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
0.6 | 6.8 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.6 | 0.6 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.6 | 4.1 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.6 | 1.7 | GO:0030172 | troponin C binding(GO:0030172) |
0.6 | 8.4 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.6 | 4.5 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.6 | 1.1 | GO:0070905 | serine binding(GO:0070905) |
0.6 | 1.7 | GO:0003979 | UDP-glucose 6-dehydrogenase activity(GO:0003979) |
0.5 | 2.7 | GO:0030620 | U2 snRNA binding(GO:0030620) |
0.5 | 1.5 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
0.5 | 3.1 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.5 | 4.0 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.5 | 5.9 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.5 | 3.3 | GO:0000150 | recombinase activity(GO:0000150) |
0.5 | 1.4 | GO:0051870 | methotrexate binding(GO:0051870) |
0.4 | 2.6 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.4 | 1.3 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.4 | 1.3 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.4 | 1.7 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.4 | 9.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.4 | 1.6 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.4 | 6.5 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.4 | 1.6 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
0.4 | 4.0 | GO:0015266 | protein channel activity(GO:0015266) |
0.4 | 1.2 | GO:0071723 | lipopeptide binding(GO:0071723) |
0.4 | 1.6 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
0.4 | 2.3 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.4 | 6.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.4 | 1.9 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.4 | 1.9 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.4 | 9.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.4 | 1.1 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
0.4 | 5.8 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.4 | 1.4 | GO:0019808 | polyamine binding(GO:0019808) |
0.4 | 1.1 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) |
0.4 | 1.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.4 | 1.1 | GO:0098973 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
0.3 | 1.7 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.3 | 1.7 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.3 | 4.1 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.3 | 2.0 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.3 | 1.0 | GO:0034618 | arginine binding(GO:0034618) |
0.3 | 5.6 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.3 | 3.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.3 | 9.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.3 | 2.8 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
0.3 | 54.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.3 | 7.9 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
0.3 | 1.2 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.3 | 3.0 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.3 | 3.2 | GO:0008430 | selenium binding(GO:0008430) |
0.3 | 1.8 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.3 | 6.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.3 | 2.6 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.3 | 1.1 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
0.3 | 1.4 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.3 | 0.8 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629) |
0.3 | 3.0 | GO:0036310 | annealing helicase activity(GO:0036310) |
0.3 | 4.6 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
0.3 | 5.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.3 | 5.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.2 | 0.7 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.2 | 0.7 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
0.2 | 2.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.2 | 3.8 | GO:0070402 | NADPH binding(GO:0070402) |
0.2 | 1.9 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
0.2 | 0.9 | GO:0005290 | L-histidine transmembrane transporter activity(GO:0005290) |
0.2 | 0.7 | GO:0070140 | isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140) |
0.2 | 1.1 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.2 | 5.5 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.2 | 2.5 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.2 | 1.1 | GO:0000403 | Y-form DNA binding(GO:0000403) |
0.2 | 1.3 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
0.2 | 1.5 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.2 | 1.6 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.2 | 5.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.2 | 1.1 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.2 | 1.5 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.2 | 1.3 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
0.2 | 2.0 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.2 | 0.7 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.2 | 4.9 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.2 | 3.1 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.2 | 0.5 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.2 | 1.8 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
0.2 | 5.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.2 | 0.9 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.2 | 1.4 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.2 | 1.9 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.2 | 3.4 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.2 | 5.6 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.2 | 1.7 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.2 | 2.6 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.2 | 7.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.2 | 1.0 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
0.2 | 0.6 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.2 | 0.5 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.2 | 1.1 | GO:1990405 | protein antigen binding(GO:1990405) |
0.1 | 6.7 | GO:0070888 | E-box binding(GO:0070888) |
0.1 | 1.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.1 | 7.4 | GO:0016651 | oxidoreductase activity, acting on NAD(P)H(GO:0016651) |
0.1 | 5.0 | GO:0097472 | cyclin-dependent protein kinase activity(GO:0097472) |
0.1 | 0.9 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.1 | 2.3 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.1 | 1.1 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.1 | 2.0 | GO:0016594 | glycine binding(GO:0016594) |
0.1 | 0.4 | GO:0001129 | transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
0.1 | 1.9 | GO:0032183 | SUMO binding(GO:0032183) |
0.1 | 2.8 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.1 | 2.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.1 | 0.7 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.1 | 4.1 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.1 | 0.2 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
0.1 | 15.7 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
0.1 | 0.2 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.1 | 0.7 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
0.1 | 2.0 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.1 | 2.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.1 | 1.2 | GO:0048185 | activin binding(GO:0048185) |
0.1 | 1.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.1 | 1.9 | GO:0001848 | complement binding(GO:0001848) |
0.1 | 2.7 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.1 | 0.3 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
0.1 | 2.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.1 | 0.3 | GO:0015928 | alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928) |
0.1 | 2.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.1 | 2.1 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 2.8 | GO:0070717 | poly-purine tract binding(GO:0070717) |
0.1 | 0.7 | GO:0051400 | BH domain binding(GO:0051400) |
0.1 | 1.3 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.1 | 1.1 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.1 | 1.4 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 1.6 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.1 | 0.6 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
0.1 | 1.4 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.1 | 1.1 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
0.1 | 8.6 | GO:0003774 | motor activity(GO:0003774) |
0.1 | 1.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 1.1 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.1 | 1.0 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
0.1 | 1.2 | GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) |
0.1 | 1.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 0.6 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.1 | 0.7 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.1 | 1.4 | GO:0042165 | neurotransmitter binding(GO:0042165) |
0.1 | 0.4 | GO:0008494 | translation activator activity(GO:0008494) |
0.1 | 3.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.1 | 0.4 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
0.1 | 2.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.1 | 1.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 0.5 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.1 | 1.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 0.4 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
0.1 | 0.9 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.1 | 0.3 | GO:0019211 | phosphatase activator activity(GO:0019211) |
0.1 | 2.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.1 | 0.9 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.1 | 0.9 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 0.2 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.1 | 2.0 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.1 | 2.2 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.1 | 1.0 | GO:0015923 | mannosidase activity(GO:0015923) |
0.1 | 0.3 | GO:0070878 | primary miRNA binding(GO:0070878) |
0.1 | 1.5 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.1 | 0.9 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.1 | 1.9 | GO:0005504 | fatty acid binding(GO:0005504) |
0.1 | 0.2 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) |
0.1 | 18.6 | GO:0045296 | cadherin binding(GO:0045296) |
0.1 | 0.4 | GO:0015099 | nickel cation transmembrane transporter activity(GO:0015099) |
0.1 | 8.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.1 | 0.5 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.1 | 0.4 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.1 | 0.4 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 2.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.6 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.0 | 1.0 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 2.0 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 3.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 1.0 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
0.0 | 0.6 | GO:0016646 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
0.0 | 0.2 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
0.0 | 2.4 | GO:0008237 | metallopeptidase activity(GO:0008237) |
0.0 | 0.1 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
0.0 | 1.8 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 0.2 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.0 | 0.4 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 1.1 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.0 | 8.6 | GO:0005198 | structural molecule activity(GO:0005198) |
0.0 | 2.0 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 1.9 | GO:0008173 | RNA methyltransferase activity(GO:0008173) |
0.0 | 0.8 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
0.0 | 0.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.3 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 1.2 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
0.0 | 0.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.8 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.3 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 0.3 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 0.6 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
0.0 | 0.5 | GO:0019843 | rRNA binding(GO:0019843) |
0.0 | 0.1 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
0.0 | 0.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.4 | GO:0017069 | snRNA binding(GO:0017069) |
0.0 | 0.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.1 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
0.0 | 0.2 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.0 | 0.9 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 2.0 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.3 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
0.0 | 0.0 | GO:0016635 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
0.0 | 0.8 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.3 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 0.0 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
0.0 | 0.1 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.0 | 0.0 | GO:0019779 | Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779) |
0.0 | 0.3 | GO:0002020 | protease binding(GO:0002020) |
0.0 | 0.5 | GO:0016835 | carbon-oxygen lyase activity(GO:0016835) |
0.0 | 0.9 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.0 | 0.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.0 | 0.0 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
0.0 | 0.4 | GO:0020037 | heme binding(GO:0020037) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 12.4 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.8 | 24.0 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.7 | 32.9 | PID_ATR_PATHWAY | ATR signaling pathway |
0.5 | 23.3 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.5 | 20.3 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.5 | 4.7 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
0.4 | 3.1 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.4 | 7.2 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.4 | 14.0 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.3 | 9.4 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.3 | 2.3 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.3 | 1.9 | PID_MYC_PATHWAY | C-MYC pathway |
0.2 | 1.2 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.2 | 11.3 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
0.2 | 5.2 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.2 | 4.4 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.2 | 5.5 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.2 | 4.8 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.2 | 1.3 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.2 | 4.8 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
0.2 | 15.8 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 1.5 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.1 | 5.1 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.1 | 1.5 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.1 | 1.0 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.1 | 2.8 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
0.1 | 4.5 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
0.1 | 2.4 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.1 | 2.9 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.1 | 0.1 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.1 | 5.7 | PID_E2F_PATHWAY | E2F transcription factor network |
0.1 | 8.8 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.1 | 1.4 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.1 | 1.7 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
0.1 | 1.3 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.1 | 8.1 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.1 | 0.3 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.1 | 2.1 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.1 | 1.0 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.1 | 1.6 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.1 | 1.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.1 | 3.0 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
0.1 | 0.8 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.1 | 0.1 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.1 | 1.2 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
0.1 | 0.6 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
0.1 | 1.7 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 1.8 | PID_CD8_TCR_DOWNSTREAM_PATHWAY | Downstream signaling in naïve CD8+ T cells |
0.0 | 3.2 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 1.2 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
0.0 | 1.3 | ST_FAS_SIGNALING_PATHWAY | Fas Signaling Pathway |
0.0 | 1.2 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 1.6 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 1.0 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 0.6 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 0.8 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 0.6 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
0.0 | 3.3 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.0 | 0.9 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.0 | 0.5 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.3 | 2.3 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
1.4 | 4.2 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
1.3 | 22.4 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
1.3 | 20.4 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.7 | 8.9 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Activation of the pre-replicative complex |
0.7 | 6.7 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.7 | 5.4 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.6 | 17.3 | REACTOME_KINESINS | Genes involved in Kinesins |
0.6 | 19.1 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
0.6 | 9.7 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.5 | 50.2 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.4 | 4.2 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.4 | 2.8 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
0.4 | 8.5 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.3 | 4.8 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.3 | 17.7 | REACTOME_SYNTHESIS_OF_DNA | Genes involved in Synthesis of DNA |
0.3 | 5.2 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.3 | 10.4 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.3 | 1.2 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
0.3 | 23.7 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.3 | 4.8 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.3 | 9.2 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
0.3 | 3.4 | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
0.3 | 14.1 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.2 | 5.8 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.2 | 6.0 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.2 | 1.9 | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | Genes involved in Cytokine Signaling in Immune system |
0.2 | 5.9 | REACTOME_MRNA_CAPPING | Genes involved in mRNA Capping |
0.2 | 15.3 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.2 | 2.0 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
0.2 | 5.1 | REACTOME_LIPOPROTEIN_METABOLISM | Genes involved in Lipoprotein metabolism |
0.2 | 19.2 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.2 | 4.7 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.2 | 11.0 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.2 | 1.7 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.2 | 2.7 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
0.2 | 3.1 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.2 | 2.8 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.2 | 2.3 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.2 | 8.4 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
0.2 | 4.1 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.1 | 7.0 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 2.3 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.1 | 3.8 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.1 | 3.4 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.1 | 4.9 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.1 | 5.4 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.1 | 1.1 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.1 | 2.0 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.1 | 1.8 | REACTOME_TRNA_AMINOACYLATION | Genes involved in tRNA Aminoacylation |
0.1 | 1.5 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.1 | 2.6 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.1 | 1.1 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.1 | 0.5 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 1.1 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.1 | 1.8 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.1 | 2.2 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.1 | 0.9 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.1 | 0.6 | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | Genes involved in Formation of RNA Pol II elongation complex |
0.1 | 1.8 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.1 | 0.9 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.1 | 1.7 | REACTOME_IRON_UPTAKE_AND_TRANSPORT | Genes involved in Iron uptake and transport |
0.0 | 0.9 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.7 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 0.4 | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | Genes involved in Integration of energy metabolism |
0.0 | 3.3 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 0.3 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 2.0 | REACTOME_TRANSLATION | Genes involved in Translation |
0.0 | 1.5 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.0 | 0.8 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 0.9 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.0 | 1.5 | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
0.0 | 1.1 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
0.0 | 0.3 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 2.0 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 2.0 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 0.8 | REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION | Genes involved in PPARA Activates Gene Expression |
0.0 | 0.2 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.0 | 0.2 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.0 | 0.3 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 0.2 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 0.5 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |