Motif ID: Pitx2_Otx2

Z-value: 1.599

Transcription factors associated with Pitx2_Otx2:

Gene SymbolEntrez IDGene Name
Otx2 ENSMUSG00000021848.9 Otx2
Pitx2 ENSMUSG00000028023.10 Pitx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Otx2mm10_v2_chr14_-_48665098_486652460.601.1e-06Click!
Pitx2mm10_v2_chr3_+_129213920_1292139380.367.5e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx2_Otx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_75782080 21.811 ENSMUST00000181224.1
AU020206
expressed sequence AU020206
chr6_-_88898664 18.552 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr2_+_164562579 14.197 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr9_-_70421533 14.109 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr11_-_106998483 14.048 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr4_-_117182623 13.348 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr14_-_47411666 10.731 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr18_+_34751803 10.470 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr17_+_35861318 10.126 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr14_-_20181773 9.543 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr16_+_30065333 9.214 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr9_+_119357381 9.209 ENSMUST00000039610.8
Xylb
xylulokinase homolog (H. influenzae)
chr18_-_74207771 9.050 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr14_-_47418407 8.901 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr11_+_97029925 8.418 ENSMUST00000021249.4
Scrn2
secernin 2
chr3_-_36571952 8.279 ENSMUST00000029270.3
Ccna2
cyclin A2
chr14_+_55824795 8.221 ENSMUST00000024179.5
ENSMUST00000172271.1
Nfatc4

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4

chr7_+_16992708 7.933 ENSMUST00000094805.4
Ccdc8
coiled-coil domain containing 8
chr10_-_128180265 7.585 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr1_-_175979114 7.432 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr7_+_16781341 7.372 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr7_-_99353104 7.351 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr11_-_60811228 7.235 ENSMUST00000018744.8
Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr6_+_56017489 7.039 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr8_+_127447669 6.975 ENSMUST00000159511.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr17_+_80127447 6.796 ENSMUST00000039205.4
Galm
galactose mutarotase
chr10_+_128238034 6.725 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr1_+_135232045 6.693 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr15_-_82244716 6.667 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr8_+_114133557 6.474 ENSMUST00000073521.5
ENSMUST00000066514.6
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr17_+_35861343 6.429 ENSMUST00000172931.1
Nrm
nurim (nuclear envelope membrane protein)
chr5_-_135251209 6.309 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr10_-_92722356 6.237 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr3_+_85915722 6.199 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr2_+_158610731 6.155 ENSMUST00000045738.4
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr18_-_60501983 5.971 ENSMUST00000042710.6
Smim3
small integral membrane protein 3
chr17_+_87635974 5.968 ENSMUST00000053577.8
Epcam
epithelial cell adhesion molecule
chr2_-_93957040 5.751 ENSMUST00000148314.2
Gm13889
predicted gene 13889
chr8_+_114133635 5.684 ENSMUST00000147605.1
ENSMUST00000134593.1
Nudt7

nudix (nucleoside diphosphate linked moiety X)-type motif 7

chr9_-_100486788 5.593 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr4_+_80910646 5.553 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr15_+_25752860 5.534 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chr11_+_117199641 5.494 ENSMUST00000093907.4
Sept9
septin 9
chr18_+_34736359 5.484 ENSMUST00000105038.2
Gm3550
predicted gene 3550
chr3_+_116878227 5.443 ENSMUST00000040260.6
Frrs1
ferric-chelate reductase 1
chr14_+_65806066 5.417 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr10_+_62947011 5.368 ENSMUST00000131422.1
Dna2
DNA replication helicase 2 homolog (yeast)
chr12_+_118846329 5.355 ENSMUST00000063918.2
Sp8
trans-acting transcription factor 8
chr10_+_20347788 5.337 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr8_+_71406003 5.327 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr3_+_131112785 5.302 ENSMUST00000098611.3
Lef1
lymphoid enhancer binding factor 1
chr3_+_55112080 5.260 ENSMUST00000044116.7
ENSMUST00000107971.2
ENSMUST00000118118.1
Spg20


spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)


chr17_+_50698525 5.252 ENSMUST00000061681.7
Gm7334
predicted gene 7334
chr5_+_110330697 5.249 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr8_+_33653238 5.241 ENSMUST00000033992.8
Gsr
glutathione reductase
chr11_-_84068554 5.159 ENSMUST00000164891.1
Dusp14
dual specificity phosphatase 14
chr11_-_84069179 5.103 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr6_+_134929118 5.088 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr6_+_134929089 5.080 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr11_-_102925086 5.080 ENSMUST00000021311.9
Kif18b
kinesin family member 18B
chr10_-_77089428 5.064 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr4_-_149137536 4.995 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
Apitd1



apoptosis-inducing, TAF9-like domain 1



chr8_-_116993459 4.958 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr11_-_106999482 4.956 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr1_-_5070281 4.938 ENSMUST00000147158.1
ENSMUST00000118000.1
Rgs20

regulator of G-protein signaling 20

chr6_-_124814288 4.915 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chr10_-_80320506 4.880 ENSMUST00000020341.8
2310011J03Rik
RIKEN cDNA 2310011J03 gene
chr11_-_84068766 4.838 ENSMUST00000018792.5
Dusp14
dual specificity phosphatase 14
chr6_-_23248264 4.691 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr11_-_106999369 4.666 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr2_+_157737401 4.649 ENSMUST00000029178.6
Ctnnbl1
catenin, beta like 1
chr11_-_73138245 4.601 ENSMUST00000052140.2
Gsg2
germ cell-specific gene 2
chr2_-_34913976 4.590 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr14_+_27039001 4.579 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr17_-_25727364 4.579 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr11_+_101442298 4.523 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr3_-_115715031 4.488 ENSMUST00000055676.2
S1pr1
sphingosine-1-phosphate receptor 1
chr14_+_67745229 4.487 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr3_-_97610156 4.479 ENSMUST00000029730.4
Chd1l
chromodomain helicase DNA binding protein 1-like
chr2_+_174415804 4.452 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr3_-_153912966 4.447 ENSMUST00000089950.4
Rabggtb
RAB geranylgeranyl transferase, b subunit
chr15_-_102667749 4.427 ENSMUST00000075630.3
Atp5g2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr1_+_92906959 4.405 ENSMUST00000060913.6
Dusp28
dual specificity phosphatase 28
chr15_+_80948484 4.399 ENSMUST00000023043.2
ENSMUST00000168756.1
ENSMUST00000164806.1
Adsl


adenylosuccinate lyase


chr7_-_118116128 4.381 ENSMUST00000128482.1
ENSMUST00000131840.1
Rps15a

ribosomal protein S15A

chr19_-_41896132 4.315 ENSMUST00000038677.3
Rrp12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr1_-_119648903 4.203 ENSMUST00000163147.1
ENSMUST00000052404.6
ENSMUST00000027632.7
Epb4.1l5


erythrocyte protein band 4.1-like 5


chr16_-_4719078 4.172 ENSMUST00000120056.1
ENSMUST00000074970.7
Nmral1

NmrA-like family domain containing 1

chr7_-_38107490 4.166 ENSMUST00000108023.3
Ccne1
cyclin E1
chr6_-_72235559 4.131 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr15_+_99006056 4.129 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr14_+_47472547 4.126 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr9_-_114982739 4.118 ENSMUST00000053150.5
Gm9846
predicted gene 9846
chr10_+_82954344 4.114 ENSMUST00000095396.3
Gm4799
predicted gene 4799
chr5_+_137778849 4.103 ENSMUST00000126126.1
ENSMUST00000031739.4
Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr8_+_85026833 4.099 ENSMUST00000047281.8
2310036O22Rik
RIKEN cDNA 2310036O22 gene
chr7_-_143460989 4.096 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr11_+_115403734 4.055 ENSMUST00000153983.1
ENSMUST00000106539.3
ENSMUST00000103036.4
Ict1


immature colon carcinoma transcript 1


chr10_+_80292453 4.048 ENSMUST00000068408.7
ENSMUST00000062674.6
Rps15

ribosomal protein S15

chr19_+_6061176 4.045 ENSMUST00000162726.3
Znhit2
zinc finger, HIT domain containing 2
chr1_-_153549697 4.045 ENSMUST00000041874.7
Npl
N-acetylneuraminate pyruvate lyase
chr11_+_44617310 4.008 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr17_-_70924958 4.004 ENSMUST00000180468.1
Gm26510
predicted gene, 26510
chr6_+_42349826 3.976 ENSMUST00000070635.6
Zyx
zyxin
chr17_+_24426676 3.968 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr19_+_37376359 3.964 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr7_-_144738520 3.949 ENSMUST00000118556.2
ENSMUST00000033393.8
Ano1

anoctamin 1, calcium activated chloride channel

chr6_-_124779686 3.942 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr11_+_61956779 3.940 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr16_-_4719148 3.923 ENSMUST00000115851.3
Nmral1
NmrA-like family domain containing 1
chr17_-_25880236 3.901 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr6_+_42350000 3.893 ENSMUST00000164375.1
Zyx
zyxin
chr14_-_8309770 3.889 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chr8_-_105707933 3.883 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr11_-_120796369 3.832 ENSMUST00000143139.1
ENSMUST00000129955.1
ENSMUST00000026151.4
ENSMUST00000167023.1
ENSMUST00000106133.1
ENSMUST00000106135.1
Dus1l





dihydrouridine synthase 1-like (S. cerevisiae)





chr6_+_83349446 3.827 ENSMUST00000136501.1
Bola3
bolA-like 3 (E. coli)
chr7_-_34812677 3.815 ENSMUST00000078686.6
Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr11_-_5152218 3.793 ENSMUST00000163299.1
ENSMUST00000062821.6
Emid1

EMI domain containing 1

chr16_+_59471775 3.746 ENSMUST00000023407.5
ENSMUST00000120667.1
ENSMUST00000120674.1
Mina


myc induced nuclear antigen


chr4_-_116994374 3.729 ENSMUST00000030446.8
Urod
uroporphyrinogen decarboxylase
chr4_-_15945359 3.712 ENSMUST00000029877.8
Decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr19_+_34922351 3.683 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr5_+_134582690 3.678 ENSMUST00000023867.6
Rfc2
replication factor C (activator 1) 2
chr7_+_16891755 3.657 ENSMUST00000078182.4
Gng8
guanine nucleotide binding protein (G protein), gamma 8
chr12_-_69159109 3.609 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr4_-_130279205 3.533 ENSMUST00000120126.2
Serinc2
serine incorporator 2
chr2_-_28466266 3.502 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr16_+_38902305 3.500 ENSMUST00000023478.7
Igsf11
immunoglobulin superfamily, member 11
chr9_-_27155418 3.497 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr7_-_118584669 3.489 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr5_+_74195281 3.476 ENSMUST00000051937.7
Rasl11b
RAS-like, family 11, member B
chr4_+_89137122 3.466 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr16_+_38562806 3.399 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr4_+_62559825 3.388 ENSMUST00000065870.7
Rgs3
regulator of G-protein signaling 3
chr8_+_70152754 3.365 ENSMUST00000072500.6
ENSMUST00000164040.1
ENSMUST00000110146.2
ENSMUST00000110143.1
ENSMUST00000110141.2
ENSMUST00000110140.1
2310045N01Rik

Mef2b



RIKEN cDNA 2310045N01 gene

myocyte enhancer factor 2B



chr8_-_71511762 3.360 ENSMUST00000048452.4
Plvap
plasmalemma vesicle associated protein
chr4_+_115000156 3.352 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr19_-_47919269 3.337 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr1_-_139377041 3.337 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr5_-_25705791 3.330 ENSMUST00000030773.7
Xrcc2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr7_-_126792469 3.303 ENSMUST00000032936.6
Ppp4c
protein phosphatase 4, catalytic subunit
chr4_-_116994354 3.300 ENSMUST00000130273.1
Urod
uroporphyrinogen decarboxylase
chr6_+_34354119 3.296 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr6_+_149582012 3.261 ENSMUST00000144085.2
Gm21814
predicted gene, 21814
chr17_-_35673738 3.246 ENSMUST00000001565.8
Gtf2h4
general transcription factor II H, polypeptide 4
chr7_+_102225812 3.225 ENSMUST00000142873.1
Pgap2
post-GPI attachment to proteins 2
chr2_-_151973840 3.223 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr14_+_74735641 3.187 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr15_-_76639840 3.182 ENSMUST00000166974.1
ENSMUST00000168185.1
Tonsl

tonsoku-like, DNA repair protein

chr8_+_70673198 3.182 ENSMUST00000034311.8
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_-_44099220 3.176 ENSMUST00000165909.1
Prom1
prominin 1
chr15_-_36308956 3.176 ENSMUST00000090170.4
Rpl7a-ps3
ribosomal protein L7A, pseudogene 3
chr14_+_7817957 3.163 ENSMUST00000052678.8
Flnb
filamin, beta
chr7_-_144738478 3.153 ENSMUST00000121758.1
Ano1
anoctamin 1, calcium activated chloride channel
chr9_-_20898592 3.148 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr11_-_84068357 3.148 ENSMUST00000100705.4
Dusp14
dual specificity phosphatase 14
chr5_-_4758216 3.139 ENSMUST00000054294.4
Fzd1
frizzled homolog 1 (Drosophila)
chr6_-_120357422 3.137 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr17_+_29090969 3.127 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr5_+_107900502 3.113 ENSMUST00000082223.6
Rpl5
ribosomal protein L5
chr10_-_130280218 3.100 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr5_-_8422582 3.090 ENSMUST00000168500.1
ENSMUST00000002368.9
Dbf4

DBF4 homolog (S. cerevisiae)

chr16_-_88056176 3.058 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
Grik1


glutamate receptor, ionotropic, kainate 1


chrM_+_8600 3.057 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr11_-_58801944 3.055 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr14_+_52110939 3.028 ENSMUST00000111600.4
Rpgrip1
retinitis pigmentosa GTPase regulator interacting protein 1
chr16_+_32419696 3.027 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1d2

Tctex1 domain containing 2

chr3_+_95111013 3.027 ENSMUST00000009102.8
Vps72
vacuolar protein sorting 72 (yeast)
chr7_+_27486910 3.026 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr3_-_90243073 3.025 ENSMUST00000107369.1
Creb3l4
cAMP responsive element binding protein 3-like 4
chr7_-_122101735 3.014 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
Ndufab1



NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1



chr13_-_119408985 3.011 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chrX_-_53269786 3.010 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr5_-_8422695 2.995 ENSMUST00000171808.1
Dbf4
DBF4 homolog (S. cerevisiae)
chr1_-_128102412 2.984 ENSMUST00000112538.1
ENSMUST00000086614.5
Zranb3

zinc finger, RAN-binding domain containing 3

chr7_+_46841475 2.967 ENSMUST00000147535.1
Ldha
lactate dehydrogenase A
chr11_-_120727226 2.938 ENSMUST00000106148.3
ENSMUST00000026144.4
Dcxr

dicarbonyl L-xylulose reductase

chr7_-_118995211 2.920 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr9_-_96478660 2.917 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr16_+_38562821 2.887 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr15_+_76904070 2.874 ENSMUST00000004072.8
Rpl8
ribosomal protein L8
chr9_-_44344159 2.873 ENSMUST00000077353.7
Hmbs
hydroxymethylbilane synthase
chr14_+_73173825 2.869 ENSMUST00000166875.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr5_+_135725713 2.857 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr9_-_96478596 2.856 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr10_-_80406811 2.842 ENSMUST00000020372.5
Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr7_-_100514800 2.823 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr11_+_69995874 2.817 ENSMUST00000101526.2
Phf23
PHD finger protein 23
chr8_+_84901928 2.816 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr1_-_93342734 2.814 ENSMUST00000027493.3
Pask
PAS domain containing serine/threonine kinase
chr6_-_134792596 2.807 ENSMUST00000100857.3
Dusp16
dual specificity phosphatase 16
chr14_-_25927672 2.784 ENSMUST00000185006.1
Tmem254a
transmembrane protein 254a
chr4_+_108579445 2.783 ENSMUST00000102744.3
Orc1
origin recognition complex, subunit 1
chr6_+_113531675 2.782 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr11_+_32205411 2.750 ENSMUST00000039601.3
ENSMUST00000149043.1
Snrnp25

small nuclear ribonucleoprotein 25 (U11/U12)

chr9_-_107635330 2.745 ENSMUST00000055704.6
Gnai2
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr11_+_69995777 2.737 ENSMUST00000018716.3
Phf23
PHD finger protein 23
chr8_+_70131327 2.730 ENSMUST00000095273.5
Nr2c2ap
nuclear receptor 2C2-associated protein
chr7_+_45163915 2.726 ENSMUST00000085374.5
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr7_+_66060338 2.725 ENSMUST00000153609.1
Snrpa1
small nuclear ribonucleoprotein polypeptide A'

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
4.0 12.1 GO:0042732 D-xylose metabolic process(GO:0042732)
3.1 9.2 GO:0021557 oculomotor nerve development(GO:0021557)
2.7 8.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
2.7 13.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
2.3 9.0 GO:0006545 glycine biosynthetic process(GO:0006545)
2.2 6.7 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
2.1 6.3 GO:1990523 bone regeneration(GO:1990523)
1.9 5.6 GO:0002865 immune response-inhibiting signal transduction(GO:0002765) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
1.9 18.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.8 5.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.8 5.3 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.8 5.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
1.7 5.2 GO:0045004 DNA replication proofreading(GO:0045004)
1.7 6.8 GO:0015825 L-serine transport(GO:0015825)
1.7 5.0 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.6 4.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
1.5 4.5 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.5 6.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.4 7.1 GO:0015705 iodide transport(GO:0015705)
1.4 6.9 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
1.3 5.3 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
1.3 5.2 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.2 3.7 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.2 6.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.2 1.2 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
1.2 7.0 GO:0003383 apical constriction(GO:0003383)
1.1 6.8 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
1.1 4.5 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
1.1 5.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.1 3.3 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
1.1 3.2 GO:0046294 formaldehyde catabolic process(GO:0046294)
1.1 3.2 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
1.1 7.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.0 3.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
1.0 3.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
1.0 24.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
1.0 3.0 GO:0036292 DNA rewinding(GO:0036292)
1.0 3.0 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
1.0 8.9 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
1.0 1.9 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
1.0 9.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.9 3.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.9 2.8 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.9 8.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.9 2.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.9 3.5 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.8 2.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166)
0.8 4.0 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.8 4.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.8 2.3 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.7 3.7 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.7 3.0 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.7 0.7 GO:0014016 neuroblast differentiation(GO:0014016)
0.7 3.7 GO:0019236 response to pheromone(GO:0019236)
0.7 2.9 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.7 2.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.7 2.6 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.6 1.9 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.6 1.9 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.6 1.9 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.6 5.7 GO:0033504 floor plate development(GO:0033504)
0.6 3.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.6 6.9 GO:0018065 protein-cofactor linkage(GO:0018065)
0.6 2.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.6 1.8 GO:0006597 spermine biosynthetic process(GO:0006597)
0.6 3.5 GO:0048318 axial mesoderm development(GO:0048318)
0.6 2.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.6 4.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.6 4.0 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.6 1.7 GO:0007525 somatic muscle development(GO:0007525)
0.6 1.1 GO:0006566 threonine metabolic process(GO:0006566)
0.5 19.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.5 2.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.5 2.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5 1.6 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.5 1.0 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.5 4.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.5 3.1 GO:0032229 negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.5 2.5 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.5 3.5 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.5 2.0 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.5 2.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.5 5.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.5 3.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.5 1.4 GO:1901355 response to rapamycin(GO:1901355)
0.5 3.3 GO:0042148 strand invasion(GO:0042148)
0.4 2.6 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.4 1.3 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4 1.3 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.4 2.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.4 2.0 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.4 4.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.4 1.6 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.4 2.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 3.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.4 1.2 GO:0016598 protein arginylation(GO:0016598)
0.4 1.2 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.4 3.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.4 11.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.4 1.9 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.4 1.9 GO:0090666 telomere assembly(GO:0032202) scaRNA localization to Cajal body(GO:0090666)
0.4 3.7 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4 2.6 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.4 1.9 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.4 1.5 GO:0097694 leptotene(GO:0000237) establishment of RNA localization to telomere(GO:0097694)
0.4 1.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 1.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.4 1.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.4 2.9 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.4 3.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.4 0.7 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.4 1.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.4 1.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 1.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 5.1 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.3 1.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.3 1.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.3 2.0 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 0.3 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.3 0.9 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.3 3.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.3 1.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 1.6 GO:0015822 ornithine transport(GO:0015822)
0.3 4.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 2.8 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 3.4 GO:0070836 caveola assembly(GO:0070836)
0.3 1.9 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.3 11.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 2.7 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.3 2.1 GO:0031424 keratinization(GO:0031424)
0.3 1.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.3 1.7 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.3 1.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.3 2.9 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.3 1.7 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.3 2.5 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.3 2.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 1.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 0.8 GO:0036166 phenotypic switching(GO:0036166)
0.3 1.6 GO:0036337 Fas signaling pathway(GO:0036337)
0.3 1.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 1.8 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.3 1.3 GO:0097194 execution phase of apoptosis(GO:0097194)
0.3 4.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 1.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.3 1.3 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.3 1.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 0.8 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 1.8 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 1.0 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.3 1.5 GO:0044375 regulation of peroxisome size(GO:0044375)
0.3 1.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.3 0.8 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 10.9 GO:0043029 T cell homeostasis(GO:0043029)
0.2 8.3 GO:0016572 histone phosphorylation(GO:0016572)
0.2 0.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 7.2 GO:0006270 DNA replication initiation(GO:0006270)
0.2 3.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 1.2 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.2 4.5 GO:0031297 replication fork processing(GO:0031297)
0.2 1.4 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 1.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 5.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 0.5 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 1.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 1.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 3.2 GO:0003334 keratinocyte development(GO:0003334)
0.2 0.9 GO:0002339 B cell selection(GO:0002339)
0.2 0.9 GO:0015817 histidine transport(GO:0015817)
0.2 4.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 1.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 2.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.1 GO:1905155 apolipoprotein A-I-mediated signaling pathway(GO:0038027) positive regulation of phagocytosis, engulfment(GO:0060100) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of membrane invagination(GO:1905155)
0.2 2.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.2 2.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 4.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.2 5.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 0.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 3.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.2 6.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 6.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 1.8 GO:0070475 rRNA base methylation(GO:0070475)
0.2 2.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 2.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 1.2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 0.6 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 0.6 GO:0036233 glycine import(GO:0036233)
0.2 3.8 GO:0016486 peptide hormone processing(GO:0016486)
0.2 1.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 3.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 1.5 GO:0008343 adult feeding behavior(GO:0008343)
0.2 1.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 2.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 0.9 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 0.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 0.4 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 2.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 1.6 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.9 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 3.9 GO:0045760 positive regulation of action potential(GO:0045760)
0.2 0.7 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 0.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 3.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.2 2.7 GO:0030903 notochord development(GO:0030903)
0.2 0.7 GO:0030576 Cajal body organization(GO:0030576)
0.2 1.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 2.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.2 3.3 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 1.7 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.2 5.1 GO:0006739 NADP metabolic process(GO:0006739)
0.2 0.9 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 1.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.7 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 7.7 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.7 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.5 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 11.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 1.0 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 2.1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.8 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.1 1.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.8 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 1.8 GO:0042407 cristae formation(GO:0042407)
0.1 1.5 GO:0036035 osteoclast development(GO:0036035)
0.1 2.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 8.3 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.1 0.9 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.1 1.6 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 3.2 GO:0006825 copper ion transport(GO:0006825)
0.1 3.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 1.2 GO:0060347 heart trabecula formation(GO:0060347) amyloid fibril formation(GO:1990000)
0.1 0.3 GO:0031622 positive regulation of fever generation(GO:0031622)
0.1 1.0 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 1.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 16.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 5.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.7 GO:2000096 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 2.4 GO:0001779 natural killer cell differentiation(GO:0001779)
0.1 3.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 7.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 4.7 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.1 0.3 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.0 GO:0046686 response to cadmium ion(GO:0046686)
0.1 1.3 GO:0060325 head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.1 5.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:1904046 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 4.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.4 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 2.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.6 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 1.5 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 1.0 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 1.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.9 GO:1900194 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 11.1 GO:0031109 microtubule polymerization or depolymerization(GO:0031109)
0.1 1.5 GO:0060009 Sertoli cell development(GO:0060009)
0.1 5.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.3 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368) positive regulation of DNA-templated transcription, elongation(GO:0032786) positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.1 1.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 1.0 GO:0051601 exocyst localization(GO:0051601)
0.1 1.4 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 0.8 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.4 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 2.1 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.1 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.2 GO:0007398 ectoderm development(GO:0007398)
0.1 0.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 0.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.6 GO:0021554 optic nerve development(GO:0021554)
0.1 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 1.0 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 3.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.7 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 1.7 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.6 GO:0016180 snRNA processing(GO:0016180)
0.1 2.3 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.1 0.4 GO:0090383 phagosome acidification(GO:0090383)
0.1 3.0 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 2.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 1.7 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.1 1.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.7 GO:1902083 cellular response to hydroperoxide(GO:0071447) negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.7 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.1 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 2.8 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.3 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.4 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 2.2 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788)
0.1 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 1.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 1.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.3 GO:0070474 regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 2.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0 1.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0044068 modulation by symbiont of host cellular process(GO:0044068)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 1.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.9 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.1 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) actin filament severing(GO:0051014) negative regulation of actin nucleation(GO:0051126)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.9 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.3 GO:0071353 response to interleukin-4(GO:0070670) cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 1.0 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 1.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.4 GO:0052548 regulation of endopeptidase activity(GO:0052548)
0.0 0.2 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.3 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.2 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.2 GO:0045333 cellular respiration(GO:0045333)
0.0 1.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0043039 tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039)
0.0 0.3 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.5 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.0 GO:0006702 androgen biosynthetic process(GO:0006702)
0.0 0.3 GO:0043966 histone H3 acetylation(GO:0043966)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 21.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.0 14.1 GO:0001940 male pronucleus(GO:0001940)
1.9 5.8 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.6 6.2 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.4 4.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.3 7.9 GO:1990393 3M complex(GO:1990393)
1.3 5.1 GO:0032021 NELF complex(GO:0032021)
1.2 6.2 GO:0044316 cone cell pedicle(GO:0044316)
1.2 19.6 GO:0031616 spindle pole centrosome(GO:0031616)
1.1 3.2 GO:0035101 FACT complex(GO:0035101)
1.1 3.2 GO:0071914 prominosome(GO:0071914)
1.0 5.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.0 3.1 GO:0070557 PCNA-p21 complex(GO:0070557)
1.0 5.1 GO:0000235 astral microtubule(GO:0000235)
1.0 6.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.0 16.7 GO:0005652 nuclear lamina(GO:0005652)
1.0 3.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.9 2.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.9 8.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.9 4.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.9 7.0 GO:0033269 internode region of axon(GO:0033269)
0.8 2.4 GO:0000814 ESCRT II complex(GO:0000814)
0.8 3.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.8 3.0 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.7 5.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.7 9.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.7 2.1 GO:1990047 spindle matrix(GO:1990047)
0.7 1.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.7 3.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.6 2.5 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.6 1.9 GO:0000811 GINS complex(GO:0000811)
0.6 6.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.6 1.8 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.6 3.5 GO:0033010 paranodal junction(GO:0033010)
0.5 2.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.5 6.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.5 3.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 1.5 GO:0000801 central element(GO:0000801)
0.5 5.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.5 35.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.5 5.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.5 1.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 6.9 GO:0031105 septin complex(GO:0031105)
0.4 1.8 GO:0070552 BRISC complex(GO:0070552)
0.4 4.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.4 4.8 GO:0005688 U6 snRNP(GO:0005688)
0.4 1.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 5.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.4 5.8 GO:0000974 Prp19 complex(GO:0000974)
0.4 5.0 GO:0031528 microvillus membrane(GO:0031528)
0.4 2.1 GO:0001533 cornified envelope(GO:0001533)
0.4 3.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.4 21.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 1.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.4 1.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.4 1.6 GO:0005745 m-AAA complex(GO:0005745)
0.4 8.9 GO:0031527 filopodium membrane(GO:0031527)
0.4 1.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.3 2.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 2.7 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.3 2.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.3 3.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.3 1.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 16.0 GO:0005871 kinesin complex(GO:0005871)
0.3 23.6 GO:0005643 nuclear pore(GO:0005643)
0.3 1.6 GO:0005796 Golgi lumen(GO:0005796)
0.3 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 1.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 1.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 0.8 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 3.0 GO:0035253 ciliary rootlet(GO:0035253)
0.2 2.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 16.8 GO:0070469 respiratory chain(GO:0070469)
0.2 2.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 3.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.5 GO:0070187 telosome(GO:0070187)
0.2 1.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.8 GO:0061617 MICOS complex(GO:0061617)
0.2 0.9 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 0.9 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 7.1 GO:0034707 chloride channel complex(GO:0034707)
0.2 4.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 1.5 GO:0036157 outer dynein arm(GO:0036157)
0.2 1.4 GO:0031415 NatA complex(GO:0031415)
0.2 1.6 GO:0000815 ESCRT III complex(GO:0000815)
0.2 1.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 3.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 1.9 GO:0042555 MCM complex(GO:0042555)
0.2 0.8 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 2.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 5.3 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 3.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.8 GO:0005686 U2 snRNP(GO:0005686)
0.1 6.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 6.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 11.7 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 1.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.3 GO:0043596 nuclear replication fork(GO:0043596)
0.1 2.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 10.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 6.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 1.1 GO:0046930 pore complex(GO:0046930)
0.1 1.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 1.9 GO:0071564 npBAF complex(GO:0071564)
0.1 1.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.0 GO:0000812 Swr1 complex(GO:0000812)
0.1 4.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 7.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.9 GO:0043218 compact myelin(GO:0043218)
0.1 5.5 GO:0016459 myosin complex(GO:0016459)
0.1 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.1 GO:0090544 BAF-type complex(GO:0090544)
0.1 4.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.0 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.1 1.0 GO:0000145 exocyst(GO:0000145)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 5.7 GO:0005811 lipid particle(GO:0005811)
0.1 5.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.5 GO:0090543 Flemming body(GO:0090543)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 1.9 GO:0030904 retromer complex(GO:0030904)
0.1 1.5 GO:0030914 STAGA complex(GO:0030914)
0.1 3.2 GO:0005902 microvillus(GO:0005902)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 23.3 GO:0016607 nuclear speck(GO:0016607)
0.1 7.2 GO:0000776 kinetochore(GO:0000776)
0.1 6.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 7.0 GO:0005903 brush border(GO:0005903)
0.1 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 2.0 GO:0097546 ciliary base(GO:0097546)
0.1 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 10.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 5.0 GO:0005814 centriole(GO:0005814)
0.1 5.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.2 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.2 GO:0030286 dynein complex(GO:0030286)
0.1 0.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 3.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.8 GO:0005840 ribosome(GO:0005840)
0.1 1.1 GO:0030686 90S preribosome(GO:0030686)
0.1 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.9 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 5.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 10.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) INO80-type complex(GO:0097346)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 4.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
3.0 9.0 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
2.8 14.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
2.1 6.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.8 7.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.7 5.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.7 5.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
1.5 4.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.3 18.6 GO:0003688 DNA replication origin binding(GO:0003688)
1.2 18.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.2 3.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.1 4.4 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.1 3.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.1 4.4 GO:0016842 amidine-lyase activity(GO:0016842)
1.1 5.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
1.1 4.3 GO:0050436 microfibril binding(GO:0050436)
1.1 3.2 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
1.0 8.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.0 3.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.0 4.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.0 4.0 GO:0003998 acylphosphatase activity(GO:0003998)
1.0 4.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.0 3.0 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
1.0 5.7 GO:0042731 PH domain binding(GO:0042731)
1.0 3.8 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.9 3.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.9 5.6 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.9 3.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.9 4.6 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.9 2.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.9 5.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.9 2.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.9 9.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.8 2.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.8 4.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.8 3.3 GO:0035877 death effector domain binding(GO:0035877)
0.8 4.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.8 2.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.8 22.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.8 8.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.7 10.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.7 5.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.7 12.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.7 5.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.7 2.9 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.7 3.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.7 2.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.7 0.7 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.7 3.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.7 2.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.6 6.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6 0.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 4.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.6 1.7 GO:0030172 troponin C binding(GO:0030172)
0.6 8.4 GO:0016805 dipeptidase activity(GO:0016805)
0.6 4.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.6 1.1 GO:0070905 serine binding(GO:0070905)
0.6 1.7 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.5 2.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.5 1.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.5 3.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 4.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 5.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.5 3.3 GO:0000150 recombinase activity(GO:0000150)
0.5 1.4 GO:0051870 methotrexate binding(GO:0051870)
0.4 2.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.4 1.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 1.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.4 1.7 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.4 9.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 1.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 6.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.4 1.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.4 4.0 GO:0015266 protein channel activity(GO:0015266)
0.4 1.2 GO:0071723 lipopeptide binding(GO:0071723)
0.4 1.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.4 2.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.4 6.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.4 1.9 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.4 1.9 GO:0008097 5S rRNA binding(GO:0008097)
0.4 9.2 GO:0008432 JUN kinase binding(GO:0008432)
0.4 1.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 5.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 1.4 GO:0019808 polyamine binding(GO:0019808)
0.4 1.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.4 1.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 1.1 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 1.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.3 4.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 2.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 1.0 GO:0034618 arginine binding(GO:0034618)
0.3 5.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 3.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 9.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 2.8 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.3 54.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 7.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.3 1.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.3 3.0 GO:0008301 DNA binding, bending(GO:0008301)
0.3 3.2 GO:0008430 selenium binding(GO:0008430)
0.3 1.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 6.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 2.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.1 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 1.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3 0.8 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.3 3.0 GO:0036310 annealing helicase activity(GO:0036310)
0.3 4.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 5.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 5.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 0.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 0.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 3.8 GO:0070402 NADPH binding(GO:0070402)
0.2 1.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 0.9 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.2 0.7 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.2 1.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 5.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 2.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 1.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 1.3 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 1.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 5.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 1.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 1.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 1.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.2 2.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 0.7 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.2 4.9 GO:0008198 ferrous iron binding(GO:0008198)
0.2 3.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 5.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.9 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 1.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 3.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 5.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 1.7 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 2.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 7.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.0 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 0.6 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.2 0.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 1.1 GO:1990405 protein antigen binding(GO:1990405)
0.1 6.7 GO:0070888 E-box binding(GO:0070888)
0.1 1.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 7.4 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 5.0 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 2.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.0 GO:0016594 glycine binding(GO:0016594)
0.1 0.4 GO:0001129 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 1.9 GO:0032183 SUMO binding(GO:0032183)
0.1 2.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 2.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 4.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 15.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 0.2 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.7 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 2.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.3 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.2 GO:0048185 activin binding(GO:0048185)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.9 GO:0001848 complement binding(GO:0001848)
0.1 2.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 2.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.3 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 2.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.8 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 0.7 GO:0051400 BH domain binding(GO:0051400)
0.1 1.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 1.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.1 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 8.6 GO:0003774 motor activity(GO:0003774)
0.1 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.2 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.1 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.4 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 0.4 GO:0008494 translation activator activity(GO:0008494)
0.1 3.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.4 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 2.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.9 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 2.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.0 GO:0015923 mannosidase activity(GO:0015923)
0.1 0.3 GO:0070878 primary miRNA binding(GO:0070878)
0.1 1.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 18.6 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.1 8.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 2.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.6 GO:0016504 peptidase activator activity(GO:0016504)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.0 GO:0002039 p53 binding(GO:0002039)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 2.4 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 1.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 8.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 2.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.9 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.8 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.2 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 2.0 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.0 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.3 GO:0002020 protease binding(GO:0002020)
0.0 0.5 GO:0016835 carbon-oxygen lyase activity(GO:0016835)
0.0 0.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.0 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.4 GO:0020037 heme binding(GO:0020037)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8 24.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.7 32.9 PID_ATR_PATHWAY ATR signaling pathway
0.5 23.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.5 20.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.5 4.7 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.4 3.1 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.4 7.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.4 14.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 9.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.3 2.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 1.9 PID_MYC_PATHWAY C-MYC pathway
0.2 1.2 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 11.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.2 5.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 4.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 5.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.2 4.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.2 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.2 4.8 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.2 15.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.5 PID_ALK2_PATHWAY ALK2 signaling events
0.1 5.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 1.5 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.0 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 2.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 4.5 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 2.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 2.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 0.1 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 5.7 PID_E2F_PATHWAY E2F transcription factor network
0.1 8.8 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.4 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 1.7 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 1.3 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 8.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 2.1 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 1.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.6 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 1.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 0.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 0.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 1.2 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 0.6 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 1.7 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.8 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.2 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.2 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 1.3 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.2 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.0 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 3.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 2.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
1.4 4.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
1.3 22.4 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.3 20.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.7 8.9 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.7 6.7 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.7 5.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.6 17.3 REACTOME_KINESINS Genes involved in Kinesins
0.6 19.1 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.6 9.7 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.5 50.2 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.4 4.2 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.4 2.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.4 8.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 4.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 17.7 REACTOME_SYNTHESIS_OF_DNA Genes involved in Synthesis of DNA
0.3 5.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.3 10.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.3 1.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 23.7 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.3 4.8 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 9.2 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.3 3.4 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3 14.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 5.8 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 6.0 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.2 1.9 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM Genes involved in Cytokine Signaling in Immune system
0.2 5.9 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.2 15.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.2 2.0 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 5.1 REACTOME_LIPOPROTEIN_METABOLISM Genes involved in Lipoprotein metabolism
0.2 19.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 4.7 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.2 11.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 1.7 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.2 2.7 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.2 3.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.8 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 2.3 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 8.4 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.2 4.1 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 7.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 3.8 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 5.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.8 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation
0.1 1.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.5 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.1 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.8 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 2.2 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.9 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 0.6 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ Genes involved in Formation of RNA Pol II elongation complex
0.1 1.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.9 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.7 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.9 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM Genes involved in Integration of energy metabolism
0.0 3.3 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.0 REACTOME_TRANSLATION Genes involved in Translation
0.0 1.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.5 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 1.1 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)