Motif ID: Pou2f3

Z-value: 0.658


Transcription factors associated with Pou2f3:

Gene SymbolEntrez IDGene Name
Pou2f3 ENSMUSG00000032015.9 Pou2f3



Activity profile for motif Pou2f3.

activity profile for motif Pou2f3


Sorted Z-values histogram for motif Pou2f3

Sorted Z-values for motif Pou2f3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou2f3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_53845086 6.976 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr5_-_109558957 2.717 ENSMUST00000044579.7
 Crlf2
cytokine receptor-like factor 2
chr13_+_94173992 2.427 ENSMUST00000121618.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr1_-_166002613 1.723 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
 Pou2f1



POU domain, class 2, transcription factor 1



chr9_-_58313189 1.640 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr18_-_82406777 1.595 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr6_-_136875794 1.466 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr6_+_125215551 1.466 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
 Vamp1


vesicle-associated membrane protein 1


chr3_+_66219909 1.445 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr1_-_75278345 1.376 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18
chr7_+_81523555 1.161 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
 2900076A07Rik



RIKEN cDNA 2900076A07 gene



chrX_-_23266751 1.140 ENSMUST00000115316.2
 Klhl13
kelch-like 13
chr17_-_47691403 1.108 ENSMUST00000113299.1
ENSMUST00000152214.1
 Gm21981
Prickle4
predicted gene 21981
prickle homolog 4 (Drosophila)
chr11_-_69605829 1.105 ENSMUST00000047889.6
 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_-_122611238 1.087 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr13_+_29016267 1.072 ENSMUST00000140415.1
 A330102I10Rik
RIKEN cDNA A330102I10 gene
chr7_+_81523531 1.054 ENSMUST00000181903.1
 2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr17_-_31636631 0.995 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
 Cbs


cystathionine beta-synthase


chr13_-_23710714 0.973 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
 Hfe


hemochromatosis


chr6_+_34476207 0.954 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
 Bpgm


2,3-bisphosphoglycerate mutase



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.7 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.3 2.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 1.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.8 GO:0051028 mRNA transport(GO:0051028)
0.5 1.6 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.3 1.4 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 1.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.4 1.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.3 1.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 1.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 1.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.3 1.0 GO:0002725 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of T cell cytokine production(GO:0002725)
0.3 1.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 1.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.3 0.9 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.2 0.8 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.8 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.0 1.6 GO:0070469 respiratory chain(GO:0070469)
0.3 1.5 GO:0070820 tertiary granule(GO:0070820)
0.3 1.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 1.0 GO:1990357 terminal web(GO:1990357)
0.0 0.9 GO:0005605 basal lamina(GO:0005605)
0.0 0.9 GO:0005902 microvillus(GO:0005902)
0.2 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.2 0.5 GO:0071920 cleavage body(GO:0071920)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.3 GO:0005125 cytokine activity(GO:0005125)
0.1 2.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.4 1.6 GO:0004966 galanin receptor activity(GO:0004966)
0.1 1.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 1.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.1 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.3 1.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 1.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 1.0 GO:1990459 beta-2-microglobulin binding(GO:0030881) transferrin receptor binding(GO:1990459)
0.1 1.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.3 0.8 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.2 0.8 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.0 ST_ADRENERGIC Adrenergic Pathway
0.0 1.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.3 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.5 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 0.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation