Motif ID: Pou5f1
Z-value: 1.140
Transcription factors associated with Pou5f1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Pou5f1 | ENSMUSG00000024406.10 | Pou5f1 |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 148 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 24.2 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.4 | 14.8 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 1.1 | 14.7 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
| 0.3 | 14.7 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
| 0.2 | 14.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.2 | 13.5 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 3.9 | 11.6 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.4 | 11.4 | GO:0030325 | adrenal gland development(GO:0030325) |
| 2.3 | 9.3 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.6 | 9.0 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
| 0.6 | 8.6 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 1.6 | 8.2 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.6 | 8.1 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.1 | 8.1 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.6 | 8.0 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.6 | 7.9 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.2 | 6.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.9 | 6.0 | GO:0042756 | drinking behavior(GO:0042756) |
| 0.7 | 5.9 | GO:0032308 | positive regulation of prostaglandin secretion(GO:0032308) |
| 0.5 | 5.8 | GO:0072189 | ureter development(GO:0072189) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 66 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 16.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.8 | 15.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.1 | 14.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.8 | 14.0 | GO:0098839 | postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634) |
| 0.2 | 10.7 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 10.6 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 1.7 | 9.9 | GO:0044308 | axonal spine(GO:0044308) |
| 0.4 | 7.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 7.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 7.2 | GO:0005769 | early endosome(GO:0005769) |
| 0.2 | 7.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 6.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.4 | 5.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 5.4 | GO:0015629 | actin cytoskeleton(GO:0015629) |
| 0.3 | 5.2 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 4.8 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 4.8 | GO:0034702 | ion channel complex(GO:0034702) |
| 0.7 | 4.7 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.5 | 4.7 | GO:0000805 | X chromosome(GO:0000805) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 105 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 19.1 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 0.6 | 14.7 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 13.5 | GO:0003779 | actin binding(GO:0003779) |
| 0.3 | 13.3 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 11.9 | GO:0016887 | ATPase activity(GO:0016887) |
| 3.9 | 11.6 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.1 | 10.5 | GO:0005262 | calcium channel activity(GO:0005262) |
| 3.1 | 9.3 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 0.1 | 8.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 8.6 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 8.1 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.1 | 7.9 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 1.6 | 7.8 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.5 | 7.8 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 6.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.3 | 5.9 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.4 | 5.7 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 0.4 | 5.6 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.3 | 5.6 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.1 | 5.6 | GO:0030552 | cAMP binding(GO:0030552) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 14.8 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 12.4 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.3 | 12.1 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.2 | 10.1 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.2 | 9.8 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.3 | 9.3 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.2 | 7.9 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.1 | 6.7 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.3 | 5.9 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 5.9 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.0 | 5.8 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 5.8 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.3 | 4.8 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.1 | 4.8 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.3 | 4.7 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.2 | 4.4 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.1 | 3.8 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.1 | 3.5 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 3.5 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.1 | 3.3 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 39 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 18.5 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.2 | 10.7 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.3 | 10.3 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.3 | 10.1 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.5 | 7.0 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 5.7 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 5.5 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.2 | 4.6 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.2 | 4.1 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 4.0 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.1 | 4.0 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.1 | 3.7 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 3.5 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.8 | 3.1 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 3.1 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.1 | 3.1 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.3 | 2.9 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 2.8 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.8 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 2.2 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
