Motif ID: Ppara

Z-value: 1.869


Transcription factors associated with Ppara:

Gene SymbolEntrez IDGene Name
Ppara ENSMUSG00000022383.7 Ppara



Activity profile for motif Ppara.

activity profile for motif Ppara


Sorted Z-values histogram for motif Ppara

Sorted Z-values for motif Ppara



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppara

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 20.239 ENSMUST00000168589.1
Sla
src-like adaptor
chr12_+_61523889 17.182 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr11_+_67586520 14.827 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr11_+_67586675 14.722 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr13_-_9878998 14.131 ENSMUST00000063093.9
Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr1_-_162478004 13.742 ENSMUST00000086074.5
ENSMUST00000070330.7
Dnm3

dynamin 3

chr17_-_35910032 12.729 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr17_-_35909626 12.468 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr7_+_91090728 11.822 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr15_+_80091320 11.815 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1

synaptogyrin 1

chr11_+_42419729 11.680 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr8_+_124793061 11.586 ENSMUST00000041106.7
Trim67
tripartite motif-containing 67
chr5_-_44799643 11.559 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr8_+_124793013 11.260 ENSMUST00000167588.1
Trim67
tripartite motif-containing 67
chr17_-_91088726 11.135 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
Nrxn1



neurexin I



chr12_+_109545390 11.048 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr5_+_150259922 11.017 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr11_+_7063423 10.819 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chrX_-_72656135 10.799 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr15_+_100761741 10.508 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr11_-_6065538 10.440 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr10_+_123264076 10.341 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr15_-_45114926 10.336 ENSMUST00000022967.5
Kcnv1
potassium channel, subfamily V, member 1
chr17_+_5492558 10.080 ENSMUST00000089185.4
Zdhhc14
zinc finger, DHHC domain containing 14
chr14_-_23803304 10.046 ENSMUST00000179836.1
ENSMUST00000172099.2
ENSMUST00000065788.8
ENSMUST00000179097.1
ENSMUST00000177634.1
ENSMUST00000074983.6
ENSMUST00000163322.2
ENSMUST00000100831.4
Kcnma1







potassium large conductance calcium-activated channel, subfamily M, alpha member 1







chr7_-_25005895 10.025 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr8_+_118283719 9.936 ENSMUST00000117160.1
Cdh13
cadherin 13
chr19_-_57314896 9.788 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr2_+_71981184 9.520 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr7_-_98162318 9.500 ENSMUST00000107112.1
Capn5
calpain 5
chr16_-_44139630 9.474 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr6_-_142964404 9.312 ENSMUST00000032421.3
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr4_-_46991842 9.145 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr4_+_123183722 9.094 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr15_-_79804717 9.070 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr5_+_117781017 8.763 ENSMUST00000138579.2
Nos1
nitric oxide synthase 1, neuronal
chr11_-_42000532 8.594 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr6_-_124768330 8.515 ENSMUST00000135626.1
Eno2
enolase 2, gamma neuronal
chr10_-_64090265 8.414 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr1_-_167393826 8.373 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr5_+_35056813 8.347 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
Dok7


docking protein 7


chr1_+_32172711 7.905 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr11_+_97450136 7.884 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr2_+_170731807 7.786 ENSMUST00000029075.4
Dok5
docking protein 5
chr17_+_91088493 7.727 ENSMUST00000095183.1
Gm10308
predicted gene 10308
chr6_+_96115249 7.624 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr12_+_29528382 7.543 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr16_-_4523056 7.536 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr5_-_66514815 7.530 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr9_-_21037775 7.477 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr5_-_106696819 7.466 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr9_-_106656081 7.360 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr1_+_159737510 7.232 ENSMUST00000111669.3
Tnr
tenascin R
chr3_-_36690118 7.207 ENSMUST00000029271.4
Trpc3
transient receptor potential cation channel, subfamily C, member 3
chr6_-_138422898 7.160 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr10_-_81025521 7.114 ENSMUST00000144640.1
Diras1
DIRAS family, GTP-binding RAS-like 1
chr10_-_109764840 7.110 ENSMUST00000163071.1
Nav3
neuron navigator 3
chr1_+_75375271 7.091 ENSMUST00000087122.5
Speg
SPEG complex locus
chr14_+_58070547 7.058 ENSMUST00000165526.1
Fgf9
fibroblast growth factor 9
chr10_-_119240006 7.054 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chr15_+_80287234 7.006 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr4_-_134254076 6.946 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr19_-_46327121 6.883 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr4_+_13751297 6.864 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_158562199 6.835 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr12_-_67221221 6.828 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr1_-_136260873 6.791 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr7_+_121707189 6.777 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr11_-_33147400 6.766 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr11_-_75796048 6.755 ENSMUST00000021209.7
Doc2b
double C2, beta
chr11_-_74590065 6.735 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr2_-_7396192 6.713 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr11_-_37235882 6.711 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr15_+_30172570 6.676 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr2_+_178119166 6.646 ENSMUST00000108916.1
Phactr3
phosphatase and actin regulator 3
chr10_-_64090241 6.533 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr3_-_107517321 6.513 ENSMUST00000166892.1
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr1_-_84696182 6.440 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr10_-_89257790 6.399 ENSMUST00000045601.7
Ano4
anoctamin 4
chr2_+_178118975 6.373 ENSMUST00000108917.1
Phactr3
phosphatase and actin regulator 3
chr5_+_66968559 6.359 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr1_+_181352618 6.350 ENSMUST00000161880.1
ENSMUST00000027795.7
Cnih3

cornichon homolog 3 (Drosophila)

chr7_-_141429351 6.350 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
Cend1


cell cycle exit and neuronal differentiation 1


chr7_-_74554474 6.284 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr5_-_106696530 6.251 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chr12_+_87026564 6.189 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr7_-_141429433 6.148 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr2_-_13011747 6.016 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr11_-_3504766 5.982 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr6_-_118757974 5.948 ENSMUST00000112825.2
Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr11_+_98741805 5.923 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr2_-_32741016 5.906 ENSMUST00000009695.2
6330409D20Rik
RIKEN cDNA 6330409D20 gene
chr15_+_92161343 5.875 ENSMUST00000068378.5
Cntn1
contactin 1
chr11_-_3722189 5.872 ENSMUST00000102950.3
ENSMUST00000101632.3
Osbp2

oxysterol binding protein 2

chr1_-_134235420 5.858 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr6_-_85502858 5.808 ENSMUST00000161546.1
ENSMUST00000161078.1
Fbxo41

F-box protein 41

chr4_+_102760294 5.784 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr1_-_3671498 5.765 ENSMUST00000070533.4
Xkr4
X Kell blood group precursor related family member 4
chr19_-_37207293 5.758 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr10_-_33995054 5.716 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr10_-_18743691 5.678 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr1_+_134193432 5.663 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr10_-_125328957 5.627 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr17_-_24689901 5.626 ENSMUST00000007236.4
Syngr3
synaptogyrin 3
chr17_+_28575718 5.619 ENSMUST00000080780.6
Lhfpl5
lipoma HMGIC fusion partner-like 5
chr12_+_117516479 5.568 ENSMUST00000109691.2
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr11_-_42000834 5.567 ENSMUST00000070725.4
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_-_5676046 5.548 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr11_-_118248489 5.534 ENSMUST00000100181.4
Cyth1
cytohesin 1
chr16_+_11406618 5.517 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr4_+_128058962 5.516 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr2_+_72054598 5.472 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr11_+_70023905 5.464 ENSMUST00000124568.2
Dlg4
discs, large homolog 4 (Drosophila)
chr17_+_28142267 5.403 ENSMUST00000043503.3
Scube3
signal peptide, CUB domain, EGF-like 3
chr12_-_86988676 5.378 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr19_+_38264761 5.377 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr10_-_89257578 5.318 ENSMUST00000182341.1
ENSMUST00000182613.1
Ano4

anoctamin 4

chr12_-_83487708 5.312 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr4_-_20778527 5.296 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr9_-_77251829 5.293 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chr5_+_63649335 5.276 ENSMUST00000159584.1
3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr2_-_7395879 5.198 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr2_-_7081207 5.180 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr4_-_119492563 5.172 ENSMUST00000049994.7
Rimkla
ribosomal modification protein rimK-like family member A
chr15_+_84669565 5.110 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr17_+_27655572 5.093 ENSMUST00000045896.3
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr19_+_6400523 5.017 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr3_+_68572245 5.002 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr14_-_74947865 4.979 ENSMUST00000088970.5
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr2_+_112265809 4.979 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr18_+_63708689 4.954 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr2_+_136713444 4.926 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr19_+_43440404 4.901 ENSMUST00000165311.1
Cnnm1
cyclin M1
chr19_+_57611020 4.901 ENSMUST00000077282.5
Atrnl1
attractin like 1
chr1_+_127204986 4.879 ENSMUST00000038361.4
Mgat5
mannoside acetylglucosaminyltransferase 5
chr16_-_4679703 4.865 ENSMUST00000038552.6
ENSMUST00000090480.4
Coro7

coronin 7

chr4_-_141599835 4.852 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
Fblim1



filamin binding LIM protein 1



chr4_+_54945038 4.851 ENSMUST00000133895.1
Zfp462
zinc finger protein 462
chr19_-_37176055 4.847 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr5_+_35057059 4.807 ENSMUST00000050709.3
Dok7
docking protein 7
chr5_+_130144861 4.800 ENSMUST00000040616.2
Kctd7
potassium channel tetramerisation domain containing 7
chr4_+_138250403 4.796 ENSMUST00000105818.1
ENSMUST00000105824.1
ENSMUST00000124239.1
Kif17
Sh2d5

kinesin family member 17
SH2 domain containing 5

chr16_-_34095983 4.784 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr16_+_10545390 4.700 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr7_-_142095266 4.696 ENSMUST00000039926.3
Dusp8
dual specificity phosphatase 8
chr7_+_46397648 4.682 ENSMUST00000160433.1
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr3_-_127409014 4.681 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
Ank2


ankyrin 2, brain


chr11_+_103103051 4.625 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chr2_+_32628390 4.618 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr5_-_24995748 4.617 ENSMUST00000076306.5
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr7_+_45896941 4.579 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr5_-_113015473 4.532 ENSMUST00000065167.4
Adrbk2
adrenergic receptor kinase, beta 2
chr4_+_41941572 4.493 ENSMUST00000108028.2
ENSMUST00000153997.1
Gm20878

predicted gene, 20878

chr8_+_36457548 4.484 ENSMUST00000135373.1
ENSMUST00000147525.1
6430573F11Rik

RIKEN cDNA 6430573F11 gene

chr6_-_59024340 4.484 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr5_+_66968416 4.475 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr11_-_95699143 4.474 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr6_-_59024470 4.470 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr4_-_116017854 4.461 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr1_-_155417283 4.452 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chrX_-_136203637 4.450 ENSMUST00000151592.1
ENSMUST00000131510.1
ENSMUST00000066819.4
Tceal5


transcription elongation factor A (SII)-like 5


chr7_-_74554726 4.430 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr16_+_4036942 4.418 ENSMUST00000137748.1
ENSMUST00000006136.4
ENSMUST00000157044.1
ENSMUST00000120009.1
Dnase1



deoxyribonuclease I



chr7_+_43797567 4.391 ENSMUST00000085461.2
Klk8
kallikrein related-peptidase 8
chr2_-_152951456 4.391 ENSMUST00000123121.2
Dusp15
dual specificity phosphatase-like 15
chr5_-_18360384 4.389 ENSMUST00000074694.5
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr4_-_11966368 4.385 ENSMUST00000056050.4
ENSMUST00000108299.1
ENSMUST00000108297.2
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr4_+_138250462 4.370 ENSMUST00000105823.1
Sh2d5
SH2 domain containing 5
chr11_-_98775333 4.338 ENSMUST00000064941.6
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr11_+_85353156 4.331 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
Bcas3





breast carcinoma amplified sequence 3





chr15_+_80097866 4.326 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr2_+_166805506 4.310 ENSMUST00000099078.3
Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chrX_+_86191764 4.288 ENSMUST00000026036.4
Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr6_-_28830345 4.270 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr15_+_73723131 4.264 ENSMUST00000165541.1
ENSMUST00000167582.1
Ptp4a3

protein tyrosine phosphatase 4a3

chr1_-_87573825 4.237 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chrX_-_143933204 4.213 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr14_-_20794009 4.209 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr3_-_127408937 4.196 ENSMUST00000183095.1
ENSMUST00000182610.1
Ank2

ankyrin 2, brain

chr19_-_45998479 4.173 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr6_-_137571007 4.154 ENSMUST00000100841.2
Eps8
epidermal growth factor receptor pathway substrate 8
chr14_-_36968679 4.149 ENSMUST00000067700.6
Ccser2
coiled-coil serine rich 2
chr2_+_29965560 4.121 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
Sptan1





spectrin alpha, non-erythrocytic 1





chr2_-_80128834 4.110 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr11_+_97801917 4.104 ENSMUST00000127033.2
Lasp1
LIM and SH3 protein 1
chr6_-_99028874 4.103 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr10_+_127165118 4.102 ENSMUST00000006914.9
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr1_+_75400070 4.102 ENSMUST00000113589.1
Speg
SPEG complex locus
chr7_+_130865835 4.094 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr5_+_117120120 4.088 ENSMUST00000111978.1
Taok3
TAO kinase 3
chr1_-_13374072 4.080 ENSMUST00000068304.6
ENSMUST00000006037.6
Ncoa2

nuclear receptor coactivator 2

chr18_+_37955544 4.018 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr2_-_112480817 3.987 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr17_+_27655509 3.986 ENSMUST00000114873.1
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr17_+_27655643 3.977 ENSMUST00000114872.1
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr2_-_80129458 3.956 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr6_-_124863877 3.954 ENSMUST00000046893.7
Gpr162
G protein-coupled receptor 162
chr14_-_108914237 3.940 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chr9_-_77251871 3.922 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr6_-_8778439 3.903 ENSMUST00000115520.1
ENSMUST00000038403.5
ENSMUST00000115518.1
Ica1


islet cell autoantigen 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 25.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
4.2 12.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
4.2 12.5 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
4.0 16.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
3.9 11.7 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
3.7 15.0 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
3.6 18.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
3.5 10.4 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
3.4 13.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
3.3 29.5 GO:0071420 cellular response to histamine(GO:0071420)
2.9 8.8 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
2.8 11.1 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
2.4 7.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
2.1 18.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
2.0 9.9 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
2.0 5.9 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
2.0 5.9 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.8 5.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
1.8 7.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
1.7 6.8 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
1.7 11.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
1.6 4.7 GO:0045204 MAPK export from nucleus(GO:0045204)
1.4 4.3 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
1.4 4.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
1.4 8.5 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
1.4 5.6 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.3 2.7 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
1.3 6.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
1.3 3.8 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
1.2 11.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
1.2 22.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
1.2 5.8 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.1 5.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.1 3.4 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
1.1 4.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.1 4.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
1.1 9.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
1.1 2.1 GO:0006642 triglyceride mobilization(GO:0006642)
1.1 14.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
1.1 3.2 GO:0007341 penetration of zona pellucida(GO:0007341)
1.0 4.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
1.0 3.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
1.0 6.0 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
1.0 19.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
1.0 3.9 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
1.0 4.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.9 8.5 GO:0009644 response to high light intensity(GO:0009644)
0.9 4.7 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.9 12.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.9 5.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.9 12.8 GO:0030238 male sex determination(GO:0030238)
0.9 3.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.9 3.6 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278)
0.9 1.8 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.9 2.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.8 11.8 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.8 6.7 GO:0097264 self proteolysis(GO:0097264)
0.8 10.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.8 16.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8 2.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.8 20.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.8 15.0 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.8 2.4 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.8 7.8 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.8 3.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.8 7.0 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.8 4.6 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.8 7.7 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.8 2.3 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.8 6.0 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.7 4.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.7 2.9 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.7 2.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.7 3.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.7 2.8 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.7 3.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.7 4.7 GO:0006102 isocitrate metabolic process(GO:0006102)
0.7 8.0 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.6 7.0 GO:0014850 response to muscle activity(GO:0014850)
0.6 26.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.6 1.9 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.6 12.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.6 5.0 GO:0071472 cellular response to salt stress(GO:0071472)
0.6 15.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.6 3.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.6 4.8 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.6 2.9 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.6 2.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.6 3.5 GO:0015879 carnitine transport(GO:0015879)
0.6 1.7 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.6 5.1 GO:0038203 TORC2 signaling(GO:0038203)
0.6 10.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.6 3.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.6 2.8 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.6 7.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.5 4.4 GO:0031642 negative regulation of myelination(GO:0031642)
0.5 1.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.5 7.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.5 4.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.5 3.2 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 4.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.5 6.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.5 2.6 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.5 1.5 GO:0060003 copper ion export(GO:0060003) cellular response to manganese ion(GO:0071287)
0.5 6.4 GO:0007220 Notch receptor processing(GO:0007220)
0.5 16.7 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.5 3.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.5 2.4 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.5 1.8 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.5 4.1 GO:0001574 ganglioside biosynthetic process(GO:0001574) lipid glycosylation(GO:0030259)
0.5 5.5 GO:0099645 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645) regulation of grooming behavior(GO:2000821)
0.5 1.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 9.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.4 12.0 GO:0018345 protein palmitoylation(GO:0018345)
0.4 1.3 GO:0006532 aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.4 2.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 1.3 GO:0043181 vacuolar sequestering(GO:0043181)
0.4 0.9 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.4 1.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 1.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 6.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.4 2.5 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.4 1.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.4 4.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 6.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 1.6 GO:0006848 pyruvate transport(GO:0006848)
0.4 2.0 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.4 2.8 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.4 1.2 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.4 10.2 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.4 5.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.4 1.9 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.4 1.1 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.4 6.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.4 4.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.4 2.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 0.4 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.4 1.5 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.4 2.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 2.5 GO:0033227 dsRNA transport(GO:0033227)
0.4 9.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.3 1.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.3 4.8 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.3 2.4 GO:0051004 plasma membrane to endosome transport(GO:0048227) regulation of lipoprotein lipase activity(GO:0051004)
0.3 13.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.3 3.6 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 0.6 GO:0043173 nucleotide salvage(GO:0043173)
0.3 1.3 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.3 1.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 5.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 17.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3 2.2 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.3 2.2 GO:0030242 pexophagy(GO:0030242)
0.3 4.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 0.9 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 2.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.3 1.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 2.8 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.3 2.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.3 1.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 0.8 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.3 7.4 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.2 4.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.2 2.0 GO:0021684 cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.7 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 1.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 5.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 4.1 GO:0055013 cardiac muscle cell development(GO:0055013)
0.2 1.4 GO:0051665 membrane raft localization(GO:0051665)
0.2 4.0 GO:0015701 bicarbonate transport(GO:0015701)
0.2 1.4 GO:0023021 termination of signal transduction(GO:0023021)
0.2 0.2 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.2 1.6 GO:0048520 positive regulation of behavior(GO:0048520)
0.2 4.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.2 0.2 GO:0098705 plasma membrane copper ion transport(GO:0015679) copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.2 4.8 GO:0055119 relaxation of cardiac muscle(GO:0055119)
0.2 0.7 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 1.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 2.2 GO:0051683 establishment of Golgi localization(GO:0051683)
0.2 4.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 8.6 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 0.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534) ERK5 cascade(GO:0070375)
0.2 2.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.2 1.7 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 1.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 5.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.2 4.2 GO:0006308 DNA catabolic process(GO:0006308)
0.2 0.6 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 1.6 GO:2000232 regulation of rRNA processing(GO:2000232)
0.2 1.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.2 28.7 GO:0030041 actin filament polymerization(GO:0030041)
0.2 0.6 GO:0035523 protein K29-linked deubiquitination(GO:0035523)
0.2 4.6 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2 5.4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.2 2.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 9.2 GO:0034605 cellular response to heat(GO:0034605)
0.2 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 11.8 GO:0030641 regulation of cellular pH(GO:0030641)
0.2 3.9 GO:0016358 dendrite development(GO:0016358)
0.2 2.8 GO:0015809 arginine transport(GO:0015809)
0.2 2.4 GO:0033572 transferrin transport(GO:0033572)
0.2 1.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 1.8 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.2 1.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 3.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 3.0 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.2 2.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 4.3 GO:0034063 stress granule assembly(GO:0034063)
0.2 2.1 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.2 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 2.2 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 0.6 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.2 1.2 GO:1902255 fat pad development(GO:0060613) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.2 2.1 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.1 2.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 1.5 GO:0000022 mitotic spindle elongation(GO:0000022) spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 3.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.5 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 1.8 GO:0072348 sulfur compound transport(GO:0072348)
0.1 0.8 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 3.9 GO:0010771 negative regulation of cell morphogenesis involved in differentiation(GO:0010771)
0.1 0.2 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 2.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 1.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 2.2 GO:0015858 nucleoside transport(GO:0015858)
0.1 0.5 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.1 1.1 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.2 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.3 GO:0002922 positive regulation of humoral immune response(GO:0002922) progesterone receptor signaling pathway(GO:0050847)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 2.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 1.2 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.1 1.7 GO:0015813 L-glutamate transport(GO:0015813)
0.1 1.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.2 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.1 0.8 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 2.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 4.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 23.3 GO:0051260 protein homooligomerization(GO:0051260)
0.1 1.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 5.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 7.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 14.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 2.0 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.4 GO:0060539 diaphragm development(GO:0060539)
0.1 2.4 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.5 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.1 6.5 GO:0007286 spermatid development(GO:0007286)
0.1 1.9 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.3 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.7 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.7 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 1.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 3.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 1.9 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 1.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 15.0 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.1 0.8 GO:0097484 dendrite extension(GO:0097484)
0.0 5.1 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 2.3 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 1.6 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 3.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.9 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.5 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0010612 regulation of cardiac muscle adaptation(GO:0010612)
0.0 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.2 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 2.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 5.1 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032434)
0.0 5.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.8 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 1.1 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 3.7 GO:0008361 regulation of cell size(GO:0008361)
0.0 0.4 GO:0048536 spleen development(GO:0048536)
0.0 3.3 GO:0007030 Golgi organization(GO:0007030)
0.0 2.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 1.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.7 GO:0001707 mesoderm formation(GO:0001707)
0.0 1.3 GO:0000045 autophagosome assembly(GO:0000045)
0.0 1.9 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.5 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.1 GO:0006511 ubiquitin-dependent protein catabolic process(GO:0006511)
0.0 0.3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0072534 perineuronal net(GO:0072534)
3.4 13.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
3.0 15.0 GO:0044316 cone cell pedicle(GO:0044316)
2.7 40.3 GO:1902711 GABA-A receptor complex(GO:1902711)
2.2 20.1 GO:0097427 microtubule bundle(GO:0097427)
2.0 18.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.8 9.1 GO:1902710 G-protein coupled receptor heterodimeric complex(GO:0038039) GABA receptor complex(GO:1902710)
1.8 7.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.4 4.3 GO:1990075 periciliary membrane compartment(GO:1990075)
1.4 12.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
1.3 10.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
1.2 12.4 GO:0044326 dendritic spine neck(GO:0044326)
1.2 24.4 GO:0032279 asymmetric synapse(GO:0032279)
1.0 2.1 GO:0016939 kinesin II complex(GO:0016939)
0.9 5.7 GO:0005859 muscle myosin complex(GO:0005859)
0.9 17.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.9 4.3 GO:1990130 Iml1 complex(GO:1990130)
0.8 4.1 GO:0032437 cuticular plate(GO:0032437)
0.8 13.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.8 8.8 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.8 2.4 GO:0098855 HCN channel complex(GO:0098855)
0.7 2.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.6 1.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.6 16.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.6 1.2 GO:1990812 growth cone filopodium(GO:1990812)
0.6 5.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 2.9 GO:0070826 paraferritin complex(GO:0070826)
0.6 1.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.6 2.3 GO:1902636 kinociliary basal body(GO:1902636)
0.6 4.6 GO:0001520 outer dense fiber(GO:0001520)
0.6 10.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.6 12.3 GO:0031430 M band(GO:0031430)
0.6 5.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.6 2.8 GO:0032389 MutLalpha complex(GO:0032389)
0.5 5.4 GO:0032426 stereocilium tip(GO:0032426)
0.5 1.0 GO:0097444 spine apparatus(GO:0097444)
0.4 4.3 GO:0042788 polysomal ribosome(GO:0042788)
0.4 2.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.4 4.3 GO:0000815 ESCRT III complex(GO:0000815)
0.4 2.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4 15.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.4 1.6 GO:0001651 dense fibrillar component(GO:0001651)
0.4 34.0 GO:0031594 neuromuscular junction(GO:0031594)
0.4 4.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.4 3.8 GO:0071141 SMAD protein complex(GO:0071141)
0.4 1.5 GO:0005745 m-AAA complex(GO:0005745)
0.4 11.9 GO:0051233 spindle midzone(GO:0051233)
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 6.8 GO:0043194 axon initial segment(GO:0043194)
0.4 5.3 GO:0031932 TORC2 complex(GO:0031932)
0.3 2.7 GO:0097413 Lewy body(GO:0097413)
0.3 4.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 2.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 0.9 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 2.3 GO:0042629 mast cell granule(GO:0042629)
0.3 37.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 2.2 GO:0097433 dense body(GO:0097433)
0.3 0.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 8.2 GO:0032420 stereocilium(GO:0032420)
0.2 11.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 12.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 30.2 GO:0005884 actin filament(GO:0005884)
0.2 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 10.2 GO:0031901 early endosome membrane(GO:0031901)
0.2 4.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 14.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 5.3 GO:0071565 nBAF complex(GO:0071565)
0.2 6.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 8.2 GO:0009925 basal plasma membrane(GO:0009925)
0.2 1.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 1.4 GO:0042599 lamellar body(GO:0042599)
0.2 1.8 GO:0032433 filopodium tip(GO:0032433)
0.2 4.1 GO:0048786 presynaptic active zone(GO:0048786)
0.2 2.1 GO:0030057 desmosome(GO:0030057)
0.2 2.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 5.9 GO:0097440 apical dendrite(GO:0097440)
0.2 33.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 26.9 GO:0030427 site of polarized growth(GO:0030427)
0.2 7.4 GO:0042734 presynaptic membrane(GO:0042734)
0.2 0.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 6.2 GO:0031201 SNARE complex(GO:0031201)
0.2 0.8 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.2 2.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 7.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 5.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 6.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 2.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.7 GO:0071439 clathrin complex(GO:0071439)
0.1 9.4 GO:0043204 perikaryon(GO:0043204)
0.1 1.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 7.8 GO:0005604 basement membrane(GO:0005604)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.3 GO:0043679 axon terminus(GO:0043679)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 14.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 2.3 GO:0016235 aggresome(GO:0016235)
0.1 30.3 GO:0005635 nuclear envelope(GO:0005635)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 5.4 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 2.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 4.3 GO:0032587 ruffle membrane(GO:0032587)
0.1 4.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 3.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.4 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.1 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 6.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 18.3 GO:0045202 synapse(GO:0045202)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 1.8 GO:0005776 autophagosome(GO:0005776)
0.0 2.6 GO:0005770 late endosome(GO:0005770)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0030133 transport vesicle(GO:0030133)
0.0 0.8 GO:0030141 secretory granule(GO:0030141)
0.0 38.2 GO:0016021 integral component of membrane(GO:0016021)
0.0 4.3 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
4.2 25.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
3.9 15.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
3.5 14.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
3.3 10.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
2.9 8.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
2.3 9.1 GO:0001847 opsonin receptor activity(GO:0001847)
2.3 6.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
2.0 6.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
2.0 9.9 GO:0055100 adiponectin binding(GO:0055100)
2.0 5.9 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
1.8 7.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
1.8 7.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.7 28.6 GO:0004890 GABA-A receptor activity(GO:0004890)
1.5 10.7 GO:0015198 oligopeptide transporter activity(GO:0015198)
1.5 9.1 GO:0016917 G-protein coupled GABA receptor activity(GO:0004965) GABA receptor activity(GO:0016917)
1.5 9.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.5 5.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.5 4.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.5 7.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
1.4 4.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
1.4 5.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.4 16.6 GO:0097109 neuroligin family protein binding(GO:0097109)
1.2 3.6 GO:0035500 MH2 domain binding(GO:0035500)
1.2 3.5 GO:0005124 scavenger receptor binding(GO:0005124)
1.2 8.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.1 5.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.1 4.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.1 11.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.0 3.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.0 17.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.0 4.9 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.9 12.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.9 2.6 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.8 5.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.8 3.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.8 5.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.8 2.4 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.8 10.4 GO:0050897 cobalt ion binding(GO:0050897)
0.8 30.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.8 5.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.8 15.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.7 4.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.7 2.9 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.7 4.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.7 11.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.7 10.0 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.7 2.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.7 5.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.7 2.8 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.7 20.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.7 2.7 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.7 2.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.7 4.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.7 3.9 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.6 2.5 GO:0001851 complement component C3b binding(GO:0001851)
0.6 2.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.6 1.9 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.6 2.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.6 2.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.6 1.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.6 17.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.6 5.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 2.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.6 12.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.5 1.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.5 3.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.5 4.8 GO:0030274 LIM domain binding(GO:0030274)
0.5 8.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.5 1.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.5 8.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.5 27.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.5 1.5 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.5 20.7 GO:0005158 insulin receptor binding(GO:0005158)
0.5 9.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 4.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.5 3.9 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.5 15.0 GO:0030552 cAMP binding(GO:0030552)
0.5 1.9 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.5 2.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 1.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.4 1.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 7.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.4 8.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 9.9 GO:0043274 phospholipase binding(GO:0043274)
0.4 1.7 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.4 7.2 GO:0046625 sphingolipid binding(GO:0046625)
0.4 2.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.4 4.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.4 12.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.4 3.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 2.8 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 4.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.4 1.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.4 5.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.4 1.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.4 15.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 8.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.3 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.3 4.9 GO:0031005 filamin binding(GO:0031005)
0.3 2.8 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 7.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 4.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 3.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 1.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.3 2.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 4.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 0.9 GO:0016417 S-acyltransferase activity(GO:0016417)
0.3 1.9 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.3 2.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 4.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.3 1.2 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.3 16.4 GO:0030507 spectrin binding(GO:0030507)
0.3 6.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 1.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 1.4 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.3 9.6 GO:0050699 WW domain binding(GO:0050699)
0.3 1.5 GO:0017040 ceramidase activity(GO:0017040)
0.3 0.8 GO:0009378 four-way junction helicase activity(GO:0009378)
0.3 1.8 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 7.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 1.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.2 21.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 4.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 3.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 0.6 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 5.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 2.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 5.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 0.9 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 4.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 2.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 6.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 2.4 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.2 GO:0015288 porin activity(GO:0015288)
0.2 5.6 GO:0042169 SH2 domain binding(GO:0042169)
0.2 4.3 GO:0000217 DNA secondary structure binding(GO:0000217)
0.2 7.7 GO:0070888 E-box binding(GO:0070888)
0.2 2.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 4.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 0.9 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 1.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 4.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 3.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.4 GO:0019003 GDP binding(GO:0019003)
0.1 7.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.5 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.8 GO:0002135 CTP binding(GO:0002135) sulfonylurea receptor binding(GO:0017098) TPR domain binding(GO:0030911)
0.1 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.1 GO:0048156 tau protein binding(GO:0048156)
0.1 5.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 7.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.8 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.5 GO:0004103 choline kinase activity(GO:0004103)
0.1 4.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.8 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 14.7 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 3.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 4.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 2.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 36.8 GO:0003779 actin binding(GO:0003779)
0.1 0.6 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.3 GO:0031403 lithium ion binding(GO:0031403)
0.1 3.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 12.6 GO:0005543 phospholipid binding(GO:0005543)
0.1 2.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 6.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 13.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.7 GO:0005243 gap junction channel activity(GO:0005243) wide pore channel activity(GO:0022829)
0.1 2.2 GO:0051117 ATPase binding(GO:0051117)
0.1 3.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.8 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 4.7 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.5 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 12.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 8.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 1.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 11.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 2.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 7.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 2.9 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0030249 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.0 1.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 13.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.7 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 2.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 1.3 GO:0000149 SNARE binding(GO:0000149)
0.0 4.6 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.6 3.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.6 8.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.5 9.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.4 7.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.3 14.7 PID_FGF_PATHWAY FGF signaling pathway
0.3 4.1 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.3 4.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.3 11.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.3 20.6 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.3 8.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 4.8 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.3 7.6 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 6.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.2 28.1 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.2 3.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 6.1 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.5 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 9.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 5.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.2 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 1.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.2 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 2.6 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.4 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.1 0.5 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 4.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 1.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 3.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 2.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 2.4 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 2.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 2.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.7 PID_SHP2_PATHWAY SHP2 signaling
0.0 1.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 40.3 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
1.9 15.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
1.8 14.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.3 10.7 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
1.3 16.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.2 38.7 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.9 13.4 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.8 21.2 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.7 7.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.7 4.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.5 6.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.5 13.7 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.5 21.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.5 4.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 5.9 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.5 13.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.5 9.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.5 1.4 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.4 9.8 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.4 2.2 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.4 6.9 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.4 4.9 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 11.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.3 4.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 3.3 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.3 8.4 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.3 8.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 1.8 REACTOME_SHC_MEDIATED_SIGNALLING Genes involved in SHC-mediated signalling
0.3 7.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 3.1 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 4.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.2 1.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 8.8 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 6.9 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 22.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 6.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 3.3 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 2.8 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.2 5.0 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2 1.5 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
0.2 2.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 1.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 6.8 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 6.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.2 7.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 8.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 2.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.5 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.2 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1 2.0 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 3.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.9 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.0 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.6 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 0.9 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.6 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.8 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.9 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.2 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.1 1.7 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.3 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 0.6 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 2.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.3 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 3.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.2 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 2.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.0 0.1 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock