Motif ID: Prdm14

Z-value: 0.315


Transcription factors associated with Prdm14:

Gene SymbolEntrez IDGene Name
Prdm14 ENSMUSG00000042414.7 Prdm14



Activity profile for motif Prdm14.

activity profile for motif Prdm14


Sorted Z-values histogram for motif Prdm14

Sorted Z-values for motif Prdm14



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm14

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_72355425 1.970 ENSMUST00000069695.2
ENSMUST00000132243.1
 Tmem150a

transmembrane protein 150A

chr16_+_43235856 1.758 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr4_+_119814495 1.393 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr15_+_18818895 1.360 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr7_+_18987518 1.353 ENSMUST00000063563.7
 Nanos2
nanos homolog 2 (Drosophila)
chr12_+_74297474 1.169 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr4_-_88438900 1.152 ENSMUST00000132493.1
ENSMUST00000030221.2
ENSMUST00000151280.1
 Ptplad2


protein tyrosine phosphatase-like A domain containing 2


chr7_+_114745685 1.124 ENSMUST00000136645.1
ENSMUST00000169913.1
 Insc

inscuteable homolog (Drosophila)

chr10_-_128744014 1.079 ENSMUST00000026414.7
 Dgka
diacylglycerol kinase, alpha
chr7_+_27810813 0.881 ENSMUST00000080175.6
 Zfp626
zinc finger protein 626
chr15_+_99601372 0.676 ENSMUST00000023754.5
 Aqp6
aquaporin 6
chr15_-_76307231 0.590 ENSMUST00000023222.6
ENSMUST00000164189.1
 Oplah

5-oxoprolinase (ATP-hydrolysing)

chr8_+_46492789 0.553 ENSMUST00000110371.1
 Acsl1
acyl-CoA synthetase long-chain family member 1
chr1_-_64121389 0.545 ENSMUST00000055001.3
 Klf7
Kruppel-like factor 7 (ubiquitous)
chr15_-_76307101 0.503 ENSMUST00000171340.1
 Oplah
5-oxoprolinase (ATP-hydrolysing)
chr9_+_94669876 0.480 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr2_+_91730127 0.471 ENSMUST00000099712.3
ENSMUST00000111317.2
ENSMUST00000111316.2
ENSMUST00000045705.7
 Ambra1



autophagy/beclin 1 regulator 1



chr1_-_64121456 0.442 ENSMUST00000142009.1
ENSMUST00000114086.1
 Klf7

Kruppel-like factor 7 (ubiquitous)

chr18_+_37307445 0.432 ENSMUST00000056712.2
 Pcdhb4
protocadherin beta 4
chrX_+_99042581 0.411 ENSMUST00000036606.7
 Stard8
START domain containing 8
chrM_+_7759 0.316 ENSMUST00000082407.1
ENSMUST00000082408.1
 mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr6_+_91684061 0.279 ENSMUST00000032185.7
 Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr12_-_69893162 0.256 ENSMUST00000049239.7
ENSMUST00000110570.1
 Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr18_-_70530138 0.222 ENSMUST00000161542.1
ENSMUST00000159389.1
 Poli

polymerase (DNA directed), iota

chr19_-_6067785 0.221 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
 Tm7sf2






transmembrane 7 superfamily member 2






chr17_+_33555719 0.184 ENSMUST00000087605.5
ENSMUST00000174695.1
 Myo1f

myosin IF

chr1_+_88103229 0.165 ENSMUST00000113135.3
ENSMUST00000113138.1
 Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chrX_+_13280970 0.161 ENSMUST00000000804.6
 Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr9_-_108083330 0.125 ENSMUST00000159372.1
ENSMUST00000160249.1
 Rnf123

ring finger protein 123

chr18_-_70530313 0.122 ENSMUST00000043286.8
 Poli
polymerase (DNA directed), iota
chr15_-_50890396 0.111 ENSMUST00000185183.1
 Trps1
trichorhinophalangeal syndrome I (human)
chr11_-_35980473 0.103 ENSMUST00000018993.6
 Wwc1
WW, C2 and coiled-coil domain containing 1
chr18_-_15063560 0.100 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr1_+_88134786 0.094 ENSMUST00000113134.1
ENSMUST00000140092.1
 Ugt1a6a

UDP glucuronosyltransferase 1 family, polypeptide A6A

chr6_+_92940572 0.088 ENSMUST00000181145.1
ENSMUST00000181840.1
 9530026P05Rik

RIKEN cDNA 9530026P05 gene

chr15_+_44428073 0.072 ENSMUST00000060652.3
 Eny2
enhancer of yellow 2 homolog (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0044838 germ-line stem cell population maintenance(GO:0030718) cell quiescence(GO:0044838)
0.1 1.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 2.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.7 GO:0006833 water transport(GO:0006833)
0.0 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 1.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 1.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.5 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.2 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 1.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 0.6 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 1.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism