Motif ID: Ptf1a

Z-value: 0.738


Transcription factors associated with Ptf1a:

Gene SymbolEntrez IDGene Name
Ptf1a ENSMUSG00000026735.2 Ptf1a



Activity profile for motif Ptf1a.

activity profile for motif Ptf1a


Sorted Z-values histogram for motif Ptf1a

Sorted Z-values for motif Ptf1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Ptf1a

PNG image of the network

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Top targets:


Showing 1 to 20 of 83 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_91269759 9.232 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr11_+_78324200 8.614 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr14_-_70207637 6.251 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr4_-_64046925 6.125 ENSMUST00000107377.3
 Tnc
tenascin C
chr15_-_98004634 5.093 ENSMUST00000131560.1
ENSMUST00000088355.5
 Col2a1

collagen, type II, alpha 1

chr7_-_79386943 5.029 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr15_-_98004695 4.937 ENSMUST00000023123.8
 Col2a1
collagen, type II, alpha 1
chr5_+_64970069 2.926 ENSMUST00000031080.8
 Fam114a1
family with sequence similarity 114, member A1
chr9_-_21852603 2.253 ENSMUST00000034728.7
 Dock6
dedicator of cytokinesis 6
chr19_+_16435616 2.116 ENSMUST00000025602.2
 Gna14
guanine nucleotide binding protein, alpha 14
chr7_-_4532419 1.963 ENSMUST00000094897.4
 Dnaaf3
dynein, axonemal assembly factor 3
chr2_+_31470207 1.750 ENSMUST00000102840.4
 Ass1
argininosuccinate synthetase 1
chr19_+_7056731 1.569 ENSMUST00000040261.5
 Macrod1
MACRO domain containing 1
chr10_-_126901315 1.329 ENSMUST00000026504.5
ENSMUST00000168520.1
 Xrcc6bp1

XRCC6 binding protein 1

chr11_-_109611417 1.312 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
 Wipi1


WD repeat domain, phosphoinositide interacting 1


chr11_-_82871133 1.276 ENSMUST00000071152.7
ENSMUST00000108173.3
 Rffl

ring finger and FYVE like domain containing protein

chr11_-_93965957 1.217 ENSMUST00000021220.3
 Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr7_-_140102367 1.183 ENSMUST00000142105.1
 Fuom
fucose mutarotase
chr10_-_75932468 1.169 ENSMUST00000120281.1
ENSMUST00000000924.6
 Mmp11

matrix metallopeptidase 11

chr9_-_112187898 1.061 ENSMUST00000178410.1
ENSMUST00000172380.3
 Arpp21

cyclic AMP-regulated phosphoprotein, 21


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 10.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 9.2 GO:0048663 neuron fate commitment(GO:0048663)
0.9 8.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 6.3 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
1.5 6.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 4.1 GO:0007601 visual perception(GO:0007601)
0.4 2.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 2.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.4 1.7 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.4 1.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.3 1.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.3 GO:0048199 protein localization to pre-autophagosomal structure(GO:0034497) vesicle targeting, to, from or within Golgi(GO:0048199)
0.1 1.2 GO:0006004 fucose metabolic process(GO:0006004)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.0 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.2 0.9 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 10.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 9.2 GO:0005667 transcription factor complex(GO:0005667)
0.4 6.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 5.9 GO:0005925 focal adhesion(GO:0005925)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.7 GO:0070852 cell body fiber(GO:0070852)
0.0 1.5 GO:0000776 kinetochore(GO:0000776)
0.1 1.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.1 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.1 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 10.0 GO:0042289 MHC class II protein binding(GO:0042289)
1.4 8.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 6.3 GO:0017166 vinculin binding(GO:0017166)
1.0 6.1 GO:0045545 syndecan binding(GO:0045545)
0.8 5.0 GO:0019841 retinol binding(GO:0019841)
0.1 2.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.6 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.3 GO:0002039 p53 binding(GO:0002039)
0.3 1.2 GO:0042806 fucose binding(GO:0042806)
0.1 1.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.0 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 1.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 0.9 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 0.9 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 0.7 GO:0035877 death effector domain binding(GO:0035877)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 17.2 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 3.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 2.5 PID_TNF_PATHWAY TNF receptor signaling pathway
0.2 2.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 10.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 8.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 6.3 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 5.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.3 2.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.0 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.2 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.9 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.7 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.5 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis