Motif ID: Rarb

Z-value: 0.451


Transcription factors associated with Rarb:

Gene SymbolEntrez IDGene Name
Rarb ENSMUSG00000017491.8 Rarb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rarbmm10_v2_chr14_-_16575456_16575501-0.114.2e-01Click!


Activity profile for motif Rarb.

activity profile for motif Rarb


Sorted Z-values histogram for motif Rarb

Sorted Z-values for motif Rarb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rarb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_116031047 6.601 ENSMUST00000106612.1
 Sox6
SRY-box containing gene 6
chr3_+_88081997 6.524 ENSMUST00000071812.5
 Iqgap3
IQ motif containing GTPase activating protein 3
chr1_+_90203980 5.546 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr1_+_191821444 5.372 ENSMUST00000027931.7
 Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr5_+_92897981 4.216 ENSMUST00000113051.2
 Shroom3
shroom family member 3
chr10_-_92722356 2.880 ENSMUST00000020163.6
 Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr3_-_52104891 2.810 ENSMUST00000121440.1
 Maml3
mastermind like 3 (Drosophila)
chr2_-_163417092 1.335 ENSMUST00000127038.1
 Oser1
oxidative stress responsive serine rich 1
chr1_+_4807823 1.247 ENSMUST00000027036.4
ENSMUST00000119612.2
ENSMUST00000137887.1
ENSMUST00000115529.1
ENSMUST00000150971.1
 Lypla1




lysophospholipase 1




chr15_-_98662858 1.071 ENSMUST00000162384.1
ENSMUST00000003450.8
 Ddx23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

chr2_+_30281043 0.812 ENSMUST00000143119.2
 RP23-395P6.9
RP23-395P6.9
chr16_+_38346986 0.591 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
 Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr7_+_127904079 0.581 ENSMUST00000071056.7
 Bckdk
branched chain ketoacid dehydrogenase kinase
chr19_-_8786272 0.415 ENSMUST00000176610.1
ENSMUST00000177056.1
 Taf6l

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor

chr18_+_65582390 0.388 ENSMUST00000169679.1
ENSMUST00000183326.1
 Zfp532

zinc finger protein 532

chr8_+_106683052 0.370 ENSMUST00000048359.4
 Tango6
transport and golgi organization 6
chr19_-_8786245 0.364 ENSMUST00000177216.1
 Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr7_+_108934405 0.220 ENSMUST00000033342.6
 Eif3f
eukaryotic translation initiation factor 3, subunit F
chr1_+_24177610 0.144 ENSMUST00000054588.8
 Col9a1
collagen, type IX, alpha 1
chr19_-_8786408 0.136 ENSMUST00000176496.1
 Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr11_+_105178765 0.120 ENSMUST00000106939.2
 Tlk2
tousled-like kinase 2 (Arabidopsis)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.7 6.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.6 6.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 2.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.2 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.2 0.6 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.1 5.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 2.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 4.2 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 1.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.9 GO:0043966 histone H3 acetylation(GO:0043966)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 6.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 5.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 5.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.9 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 4.2 GO:0043296 apical junction complex(GO:0043296)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 6.6 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
1.6 6.5 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0016531 copper chaperone activity(GO:0016531)
0.0 6.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 5.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 1.1 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 2.8 GO:0003713 transcription coactivator activity(GO:0003713)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 6.5 PID_RAC1_PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 5.4 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 2.8 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.1 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import