Motif ID: Rarg

Z-value: 1.076


Transcription factors associated with Rarg:

Gene SymbolEntrez IDGene Name
Rarg ENSMUSG00000001288.8 Rarg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rargmm10_v2_chr15_-_102257306_1022573700.302.7e-02Click!


Activity profile for motif Rarg.

activity profile for motif Rarg


Sorted Z-values histogram for motif Rarg

Sorted Z-values for motif Rarg



Network of associatons between targets according to the STRING database.



First level regulatory network of Rarg

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_70501116 5.564 ENSMUST00000127983.1
 Crlf1
cytokine receptor-like factor 1
chr1_-_171059390 4.091 ENSMUST00000164044.1
ENSMUST00000169017.1
 Fcgr3

Fc receptor, IgG, low affinity III

chr5_-_113015473 3.769 ENSMUST00000065167.4
 Adrbk2
adrenergic receptor kinase, beta 2
chr12_-_54203860 3.561 ENSMUST00000039516.3
 Egln3
EGL nine homolog 3 (C. elegans)
chr10_+_58813359 3.472 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr19_-_57008187 3.344 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr16_+_41532999 3.226 ENSMUST00000099761.3
 Lsamp
limbic system-associated membrane protein
chr16_+_17276291 2.982 ENSMUST00000164950.1
ENSMUST00000159242.1
 Tmem191c

transmembrane protein 191C

chr16_+_17276337 2.979 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
 Tmem191c


transmembrane protein 191C


chr13_-_51567084 2.961 ENSMUST00000021898.5
 Shc3
src homology 2 domain-containing transforming protein C3
chr6_+_135362931 2.950 ENSMUST00000032330.9
 Emp1
epithelial membrane protein 1
chr3_+_86070915 2.945 ENSMUST00000182666.1
 Sh3d19
SH3 domain protein D19
chr12_+_81026800 2.922 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
 Smoc1


SPARC related modular calcium binding 1


chr9_+_56865104 2.864 ENSMUST00000035661.5
 Cspg4
chondroitin sulfate proteoglycan 4
chr9_-_107668967 2.752 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr14_-_70207637 2.717 ENSMUST00000022682.5
 Sorbs3
sorbin and SH3 domain containing 3
chr18_-_31949571 2.716 ENSMUST00000064016.5
 Gpr17
G protein-coupled receptor 17
chr9_+_27790947 2.715 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr14_+_101840602 2.648 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr8_+_40862379 2.608 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
 Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 252 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 5.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.5 4.4 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.7 4.4 GO:1904426 positive regulation of GTP binding(GO:1904426)
0.6 4.4 GO:0015862 uridine transport(GO:0015862)
1.2 3.6 GO:1900673 olefin metabolic process(GO:1900673)
0.4 3.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.4 3.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 3.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 3.3 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 3.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.2 3.0 GO:0032060 bleb assembly(GO:0032060)
0.2 2.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 2.9 GO:0097435 fibril organization(GO:0097435)
0.1 2.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7 2.8 GO:0015817 histidine transport(GO:0015817)
0.3 2.7 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 2.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 2.7 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.9 2.6 GO:1902022 L-lysine transport(GO:1902022)
0.1 2.6 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 7.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.7 GO:0005604 basement membrane(GO:0005604)
1.9 5.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 5.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 5.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.9 3.7 GO:0044307 dendritic branch(GO:0044307)
0.1 3.1 GO:0002080 acrosomal membrane(GO:0002080)
0.6 2.5 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 2.5 GO:0043197 dendritic spine(GO:0043197)
0.0 2.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.5 GO:0000139 Golgi membrane(GO:0000139)
0.1 2.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.7 2.0 GO:0098855 HCN channel complex(GO:0098855)
0.5 2.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.9 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.8 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.4 1.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 174 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 5.6 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 5.3 GO:0005518 collagen binding(GO:0005518)
0.1 4.7 GO:0042805 actinin binding(GO:0042805)
0.9 4.4 GO:0019770 IgG receptor activity(GO:0019770)
0.2 4.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.5 3.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 3.7 GO:0070064 proline-rich region binding(GO:0070064)
0.6 3.6 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4 3.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 3.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 3.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.9 2.8 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.2 2.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.7 2.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 2.6 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.3 2.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 2.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.8 2.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 2.4 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 7.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 3.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.7 PID_IL12_2PATHWAY IL12-mediated signaling events
0.1 2.5 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.2 1.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.8 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 1.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.7 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.6 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.6 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 4.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 4.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 4.3 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.2 4.0 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 4.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 3.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 3.0 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 3.0 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 2.9 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 2.9 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.9 2.7 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.2 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.0 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 1.8 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.3 1.7 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse