Motif ID: Rhox4e_Rhox6_Vax2

Z-value: 1.205

Transcription factors associated with Rhox4e_Rhox6_Vax2:

Gene SymbolEntrez IDGene Name
Rhox4e ENSMUSG00000071770.4 Rhox4e
Rhox6 ENSMUSG00000006200.3 Rhox6
Vax2 ENSMUSG00000034777.1 Vax2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Vax2mm10_v2_chr6_+_83711232_83711288-0.292.9e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rhox4e_Rhox6_Vax2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_67113909 16.552 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr6_-_23248264 12.438 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr9_+_53771499 10.769 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr4_-_14621805 8.295 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr14_+_5517172 6.819 ENSMUST00000178220.1
Gm3488
predicted gene, 3488
chr14_+_5164535 6.819 ENSMUST00000179659.1
Gm3317
predicted gene 3317
chr14_+_3667518 6.632 ENSMUST00000112801.3
Gm3020
predicted gene 3020
chr7_-_25005895 6.090 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr4_-_14621669 5.736 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr1_+_72284367 5.606 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr16_-_42340595 5.548 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr14_-_7473073 5.399 ENSMUST00000167833.2
Gm3752
predicted gene 3752
chr14_+_3348089 5.341 ENSMUST00000178722.1
Gm2956
predicted gene 2956
chr14_-_6411578 5.199 ENSMUST00000179312.1
Gm3591
predicted gene 3591
chr4_-_14621494 5.175 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr14_-_5863663 5.078 ENSMUST00000178594.1
Gm8237
predicted gene 8237
chr14_+_3428103 5.071 ENSMUST00000178060.1
Gm3005
predicted gene 3005
chr14_+_4514758 5.053 ENSMUST00000112776.2
Gm3173
predicted gene 3173
chr14_+_4198185 4.944 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr14_+_4871156 4.941 ENSMUST00000166410.2
Gm3264
predicted gene 3264
chr14_+_4126066 4.930 ENSMUST00000167397.2
Gm8108
predicted gene 8108
chr13_-_102906046 4.895 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr14_+_4741737 4.871 ENSMUST00000178748.1
Gm3252
predicted gene 3252
chr14_-_6874257 4.811 ENSMUST00000178298.1
ENSMUST00000179374.1
Gm3667
Gm3629
predicted gene 3667
predicted gene 3629
chr14_+_4430992 4.745 ENSMUST00000164603.1
ENSMUST00000166848.1
Gm3173

predicted gene 3173

chr2_+_125136692 4.634 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr12_-_112511136 4.541 ENSMUST00000066791.5
Tmem179
transmembrane protein 179
chr14_-_6741430 4.417 ENSMUST00000100904.4
Gm3636
predicted gene 3636
chr14_-_19569553 4.387 ENSMUST00000112595.2
Gm2237
predicted gene 2237
chr14_-_6266620 4.383 ENSMUST00000096172.5
Gm3411
predicted gene 3411
chr14_+_3825596 4.346 ENSMUST00000178256.1
Gm3002
predicted gene 3002
chr2_+_65845767 4.245 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr12_+_109545390 4.205 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr13_-_102905740 4.083 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr14_+_4665094 4.043 ENSMUST00000169675.2
Gm3239
predicted gene 3239
chr2_+_65845833 3.961 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr5_+_37185897 3.790 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr3_+_55782500 3.311 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr2_+_65620829 3.293 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr12_-_40037387 2.938 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr5_-_118244861 2.859 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr3_+_55461758 2.858 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr9_-_75597643 2.845 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr9_-_55919605 2.684 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr8_-_54724317 2.675 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr8_+_107031218 2.671 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr9_-_112187766 2.454 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr15_-_60824942 2.441 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr1_-_89933290 2.192 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr18_+_12741324 1.977 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr7_+_57387304 1.967 ENSMUST00000085241.5
Gm9962
predicted gene 9962
chr15_+_59315088 1.892 ENSMUST00000100640.4
Sqle
squalene epoxidase
chr15_+_59315030 1.877 ENSMUST00000022977.7
Sqle
squalene epoxidase
chr6_+_37870786 1.825 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr3_+_121953213 1.735 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr9_+_102720287 1.721 ENSMUST00000130602.1
Amotl2
angiomotin-like 2
chr4_+_15881255 1.560 ENSMUST00000029876.1
Calb1
calbindin 1
chrM_+_7759 1.547 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr13_+_75967704 1.421 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chr6_+_145934113 1.419 ENSMUST00000032383.7
Sspn
sarcospan
chr18_+_38418946 1.410 ENSMUST00000025293.3
Ndfip1
Nedd4 family interacting protein 1
chr17_-_15527281 1.387 ENSMUST00000154293.1
ENSMUST00000054450.6
Pdcd2

programmed cell death 2

chr1_+_109983737 1.366 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr3_-_10440054 1.340 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr13_+_67833235 1.339 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr13_-_53473074 1.328 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr7_+_126950687 1.278 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr14_+_57524734 1.167 ENSMUST00000089494.4
Il17d
interleukin 17D
chr8_-_35495487 1.152 ENSMUST00000033927.6
Eri1
exoribonuclease 1
chr4_+_43493345 1.145 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr2_+_170731807 1.131 ENSMUST00000029075.4
Dok5
docking protein 5
chr5_+_29195983 1.126 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chrM_+_8600 1.111 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr13_-_92030897 1.088 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr19_-_32196393 1.024 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr2_-_69712461 1.013 ENSMUST00000102706.3
ENSMUST00000073152.6
Fastkd1

FAST kinase domains 1

chr8_+_66386292 0.985 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr14_+_3224440 0.982 ENSMUST00000112797.4
D830030K20Rik
RIKEN cDNA D830030K20 gene
chr3_-_90389884 0.935 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr4_+_108719649 0.931 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr6_+_125552948 0.913 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr3_+_103575275 0.910 ENSMUST00000090697.4
Syt6
synaptotagmin VI
chr8_+_64947177 0.863 ENSMUST00000079896.7
ENSMUST00000026595.5
Tmem192

transmembrane protein 192

chr2_-_71367749 0.852 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chrX_-_143933204 0.847 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr19_-_11604828 0.841 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr2_+_69897220 0.840 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr3_+_103575231 0.832 ENSMUST00000121834.1
Syt6
synaptotagmin VI
chr7_-_38019505 0.794 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr12_-_80643799 0.792 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr7_+_38183217 0.781 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chrX_+_150589907 0.771 ENSMUST00000080884.4
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_+_25406661 0.755 ENSMUST00000146647.1
Kank1
KN motif and ankyrin repeat domains 1
chr12_+_10390756 0.747 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr5_-_136986829 0.745 ENSMUST00000034953.7
ENSMUST00000085941.5
Znhit1

zinc finger, HIT domain containing 1

chr3_-_86548268 0.743 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr18_+_4993795 0.740 ENSMUST00000153016.1
Svil
supervillin
chr14_+_3846245 0.731 ENSMUST00000180934.1
Gm3033
predicted gene 3033
chrX_-_143933089 0.703 ENSMUST00000087313.3
Dcx
doublecortin
chr13_-_66852017 0.665 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr17_-_57031468 0.655 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr1_+_87183310 0.653 ENSMUST00000044533.8
Prss56
protease, serine 56
chr17_+_47688992 0.600 ENSMUST00000156118.1
Frs3
fibroblast growth factor receptor substrate 3
chr19_+_41933464 0.599 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr9_+_119063429 0.585 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr11_+_69838514 0.567 ENSMUST00000133967.1
ENSMUST00000094065.4
Tmem256

transmembrane protein 256

chr15_+_82256023 0.548 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr5_-_34660068 0.539 ENSMUST00000041364.9
Nop14
NOP14 nucleolar protein
chr9_+_108339048 0.529 ENSMUST00000082429.5
Gpx1
glutathione peroxidase 1
chr10_+_128337761 0.516 ENSMUST00000005826.7
Cs
citrate synthase
chr9_-_71163224 0.504 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr17_+_8849974 0.488 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr18_+_59062462 0.486 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr2_+_109917639 0.483 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr18_+_59062282 0.472 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chr2_-_168767136 0.465 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr12_-_85824506 0.462 ENSMUST00000021676.5
ENSMUST00000142331.1
0610007P14Rik

RIKEN cDNA 0610007P14 gene

chr1_-_135284075 0.458 ENSMUST00000077340.7
ENSMUST00000074357.7
Rnpep

arginyl aminopeptidase (aminopeptidase B)

chr2_-_150255591 0.454 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr15_-_36794498 0.450 ENSMUST00000110361.1
ENSMUST00000022894.7
ENSMUST00000110359.1
Ywhaz


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide


chr5_-_137531204 0.444 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr18_-_24603791 0.430 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr12_+_72536342 0.428 ENSMUST00000044352.6
Pcnxl4
pecanex-like 4 (Drosophila)
chr12_-_79190955 0.425 ENSMUST00000085254.6
Rdh11
retinol dehydrogenase 11
chr9_+_72806874 0.424 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr19_+_60811574 0.420 ENSMUST00000128357.1
ENSMUST00000119633.1
ENSMUST00000025957.8
Fam45a


family with sequence similarity 45, member A


chr2_+_121956411 0.417 ENSMUST00000110578.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr18_-_56975333 0.414 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr6_-_118479237 0.411 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr12_+_100110148 0.411 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr18_+_24603952 0.405 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr17_-_48432723 0.399 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr14_-_7450917 0.398 ENSMUST00000169555.1
Gm3755
predicted gene 3755
chr3_-_67515487 0.392 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr5_-_17888884 0.358 ENSMUST00000169095.1
Cd36
CD36 antigen
chr12_+_52699297 0.331 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr8_+_121116163 0.325 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr18_+_55057557 0.325 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr9_-_99568849 0.320 ENSMUST00000035043.5
Armc8
armadillo repeat containing 8
chr2_+_155751117 0.318 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr7_+_3645267 0.306 ENSMUST00000038913.9
Cnot3
CCR4-NOT transcription complex, subunit 3
chr2_-_168767029 0.304 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr2_+_121956651 0.289 ENSMUST00000110574.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr19_+_8802486 0.287 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr12_+_80644212 0.277 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr18_-_24603464 0.271 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr17_+_66111605 0.269 ENSMUST00000116556.2
Wash
WAS protein family homolog
chr18_+_60212080 0.250 ENSMUST00000031549.5
Gm4951
predicted gene 4951
chrM_+_7005 0.242 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr16_+_58408443 0.241 ENSMUST00000046663.7
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr2_+_174450678 0.240 ENSMUST00000016399.5
Tubb1
tubulin, beta 1 class VI
chr3_+_122274371 0.224 ENSMUST00000035776.8
Dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr17_+_27839974 0.223 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chr4_-_40722307 0.216 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr5_-_137531952 0.212 ENSMUST00000140139.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr2_-_155074447 0.209 ENSMUST00000137242.1
ENSMUST00000054607.9
Ahcy

S-adenosylhomocysteine hydrolase

chr4_+_100478806 0.207 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chr19_-_41933276 0.205 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr12_+_55303241 0.203 ENSMUST00000184766.1
ENSMUST00000183475.1
ENSMUST00000183654.1
1110008L16Rik


RIKEN cDNA 1110008L16 gene


chr4_-_118489755 0.201 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr8_+_113635550 0.184 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr13_+_59585259 0.173 ENSMUST00000168367.1
ENSMUST00000022038.7
ENSMUST00000166923.1
Naa35


N(alpha)-acetyltransferase 35, NatC auxiliary subunit


chr5_-_134946917 0.164 ENSMUST00000051401.2
Cldn4
claudin 4
chr8_-_21906412 0.159 ENSMUST00000051965.4
Defb11
defensin beta 11
chr6_-_124779686 0.150 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr5_-_43981757 0.142 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chrX_+_101429555 0.138 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chr10_-_127121125 0.134 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr6_-_54972603 0.131 ENSMUST00000060655.8
Nod1
nucleotide-binding oligomerization domain containing 1
chr13_+_90089705 0.121 ENSMUST00000012566.8
Tmem167
transmembrane protein 167
chr8_+_113635787 0.119 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr10_-_33951190 0.111 ENSMUST00000048222.4
Zufsp
zinc finger with UFM1-specific peptidase domain
chr16_+_11406618 0.110 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr5_+_135994796 0.101 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
Dtx2




deltex 2 homolog (Drosophila)




chr17_-_55915870 0.100 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr5_-_138171216 0.097 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_-_117873433 0.096 ENSMUST00000033230.7
Tha1
threonine aldolase 1
chr2_-_125782834 0.091 ENSMUST00000053699.6
Secisbp2l
SECIS binding protein 2-like
chr7_+_12927410 0.089 ENSMUST00000045870.4
2310014L17Rik
RIKEN cDNA 2310014L17 gene
chr13_-_67332525 0.083 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr10_-_61784014 0.082 ENSMUST00000020283.4
H2afy2
H2A histone family, member Y2
chr6_+_71909046 0.078 ENSMUST00000055296.8
Polr1a
polymerase (RNA) I polypeptide A
chr12_+_110601439 0.070 ENSMUST00000018851.7
Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr4_-_108118504 0.048 ENSMUST00000149106.1
Scp2
sterol carrier protein 2, liver
chr4_+_103143052 0.040 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chrX_+_150547375 0.038 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr17_+_66111529 0.030 ENSMUST00000072383.6
Wash
WAS protein family homolog
chr12_+_102128718 0.029 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chrX_-_160138375 0.027 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr2_+_36230426 0.013 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr11_-_4095344 0.012 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr18_+_4920509 0.011 ENSMUST00000126977.1
Svil
supervillin
chr18_-_34651703 0.011 ENSMUST00000025228.5
ENSMUST00000133181.1
Cdc23

CDC23 cell division cycle 23

chr5_+_31526989 0.010 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
Slc4a1ap


solute carrier family 4 (anion exchanger), member 1, adaptor protein



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 19.2 GO:0019532 oxalate transport(GO:0019532)
2.1 12.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.9 2.7 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.6 5.5 GO:0016198 axon choice point recognition(GO:0016198)
0.6 6.1 GO:0036376 sodium ion export from cell(GO:0036376)
0.6 1.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.5 2.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 1.4 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.4 1.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.4 16.6 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.3 2.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.3 1.6 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.3 1.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.3 0.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 0.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.2 0.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 0.5 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 4.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:0070543 response to linoleic acid(GO:0070543)
0.1 2.0 GO:0048240 sperm capacitation(GO:0048240)
0.1 9.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.2 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 2.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.5 GO:0015791 polyol transport(GO:0015791) bile acid secretion(GO:0032782)
0.1 1.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.7 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862) protein oxidation(GO:0018158)
0.1 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 2.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.7 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 3.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 1.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 1.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 2.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.7 GO:0035329 hippo signaling(GO:0035329)
0.0 1.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0042228 positive regulation of dendritic cell antigen processing and presentation(GO:0002606) interleukin-8 biosynthetic process(GO:0042228)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.8 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.4 GO:1904892 regulation of JAK-STAT cascade(GO:0046425) regulation of STAT cascade(GO:1904892)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 9.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.0 0.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0051225 spindle assembly(GO:0051225)
0.0 1.1 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.0 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.3 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.9 GO:0030168 platelet activation(GO:0030168)
0.0 0.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 2.7 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.3 1.8 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 0.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 5.5 GO:0031527 filopodium membrane(GO:0031527)
0.2 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 2.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.5 GO:0030689 Noc complex(GO:0030689)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.8 GO:0034709 methylosome(GO:0034709)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:0097413 Lewy body(GO:0097413)
0.1 17.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.1 17.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.5 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
1.7 19.2 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.8 5.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.6 6.1 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.4 1.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.3 1.3 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.3 2.8 GO:0005523 tropomyosin binding(GO:0005523)
0.3 1.8 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.9 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.2 0.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 3.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.2 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 12.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.0 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0050897 cobalt ion binding(GO:0050897)
0.0 9.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 1.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.6 GO:0005496 steroid binding(GO:0005496)
0.0 2.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.1 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 4.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 2.7 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 1.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.6 PID_SHP2_PATHWAY SHP2 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 16.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 19.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 6.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.2 3.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.9 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 2.7 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 1.8 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_FRS2_MEDIATED_CASCADE Genes involved in FRS2-mediated cascade
0.0 1.6 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation