Motif ID: Sox11

Z-value: 0.442


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.656.6e-08Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_16378231 1.938 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr6_-_23248264 1.622 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr16_-_50330987 1.214 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr2_+_154548888 1.174 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr14_-_47418407 1.127 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr9_+_65890237 1.114 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr2_-_79456750 1.016 ENSMUST00000041099.4
 Neurod1
neurogenic differentiation 1
chr4_-_97584612 0.908 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584605 0.906 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr1_+_82233112 0.891 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr5_+_64812336 0.863 ENSMUST00000166409.1
 Klf3
Kruppel-like factor 3 (basic)
chr5_+_14514918 0.819 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr5_-_131616599 0.792 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr13_-_99516537 0.729 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr2_+_15055274 0.698 ENSMUST00000069870.3
 Arl5b
ADP-ribosylation factor-like 5B
chr7_+_70388305 0.697 ENSMUST00000080024.5
 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr7_+_83631959 0.632 ENSMUST00000075418.7
ENSMUST00000117410.1
 Stard5

StAR-related lipid transfer (START) domain containing 5

chr9_+_52047150 0.624 ENSMUST00000163153.1
 Rdx
radixin
chr16_+_8830093 0.621 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr14_-_52213379 0.615 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0010842 retina layer formation(GO:0010842)
0.3 1.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 1.0 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 0.8 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 0.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.7 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.2 0.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.6 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.6 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.6 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.2 0.5 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.3 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.3 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.2 0.8 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 0.6 GO:0051286 cell tip(GO:0051286)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)

Gene overrepresentation in molecular_function category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 0.6 GO:0032052 bile acid binding(GO:0032052)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism