Motif ID: Sox15

Z-value: 0.460


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Showing 1 to 20 of 131 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_55445550 1.778 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr2_-_65567465 1.637 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567505 1.581 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr3_-_8964037 1.575 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr6_-_23248264 1.483 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr6_+_17491216 1.413 ENSMUST00000080469.5
Met
met proto-oncogene
chr6_+_17463927 1.342 ENSMUST00000115442.1
Met
met proto-oncogene
chr5_+_148265202 1.337 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr5_+_148265307 1.307 ENSMUST00000110514.1
Mtus2
microtubule associated tumor suppressor candidate 2
chr6_+_17463749 1.294 ENSMUST00000115443.1
Met
met proto-oncogene
chr6_+_17463826 1.151 ENSMUST00000140070.1
Met
met proto-oncogene
chr6_+_125552948 1.131 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr5_+_148265265 1.119 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr7_+_82174796 1.086 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr7_+_82175156 0.999 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr10_-_116473418 0.952 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr3_+_31902666 0.942 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chrX_+_109095359 0.917 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chrX_+_112604274 0.873 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr12_+_40446050 0.857 ENSMUST00000037488.6
Dock4
dedicator of cytokinesis 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 5.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.6 3.2 GO:0046684 response to pyrethroid(GO:0046684)
0.2 2.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.9 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 1.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.1 GO:0030168 platelet activation(GO:0030168)
0.1 1.0 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 0.9 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 0.7 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.7 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 0.6 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.6 GO:0050904 diapedesis(GO:0050904)
0.1 0.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.6 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:0072697 protein localization to cell cortex(GO:0072697)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.8 GO:0045171 intercellular bridge(GO:0045171)
0.2 3.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.0 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.2 0.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.1 0.3 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 5.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 3.2 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.4 1.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.5 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0030350 iron-responsive element binding(GO:0030350)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.2 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.3 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.7 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.6 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 1.5 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine