Motif ID: Sox2

Z-value: 3.229


Transcription factors associated with Sox2:

Gene SymbolEntrez IDGene Name
Sox2 ENSMUSG00000074637.4 Sox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox2mm10_v2_chr3_+_34649987_34650005-0.104.8e-01Click!


Activity profile for motif Sox2.

activity profile for motif Sox2


Sorted Z-values histogram for motif Sox2

Sorted Z-values for motif Sox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_138842429 23.971 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr7_-_49636847 20.294 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr7_-_115824699 19.947 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr1_+_6734827 17.661 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr5_-_112228633 16.903 ENSMUST00000182699.1
ENSMUST00000182258.1
ENSMUST00000183036.1
Miat


myocardial infarction associated transcript (non-protein coding)


chr7_-_116038734 16.788 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr9_+_118478851 16.350 ENSMUST00000150633.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478344 15.675 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr7_+_45216671 15.654 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr5_-_98030727 15.191 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr10_+_26229707 14.568 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr1_+_6487231 14.185 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chrX_-_143933089 13.212 ENSMUST00000087313.3
Dcx
doublecortin
chr14_+_61138445 13.149 ENSMUST00000089394.3
ENSMUST00000119509.1
Sacs

sacsin

chr2_+_181763315 13.066 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr4_+_62965560 12.899 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr17_-_35703971 12.790 ENSMUST00000148065.1
Ddr1
discoidin domain receptor family, member 1
chr7_-_37772868 12.673 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr6_-_56362356 12.278 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr3_-_75956888 12.145 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
Golim4


golgi integral membrane protein 4


chr11_-_114795888 11.900 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr4_-_63403330 11.773 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr8_+_45507768 11.661 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr17_-_35704000 11.375 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr1_+_136131382 11.035 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr5_-_112228900 10.886 ENSMUST00000182509.1
Miat
myocardial infarction associated transcript (non-protein coding)
chr2_-_33942111 10.582 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr11_+_119022962 10.512 ENSMUST00000026662.7
Cbx2
chromobox 2
chr1_+_6730051 10.443 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr6_-_67037399 10.409 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr7_+_99466004 10.315 ENSMUST00000037359.2
Klhl35
kelch-like 35
chr10_+_94036001 10.207 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr6_+_47244359 10.112 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chrX_-_16911774 9.955 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr6_-_23248264 9.937 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr8_-_69184177 9.904 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr10_+_80300997 9.825 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr2_+_146221921 9.708 ENSMUST00000089257.4
Insm1
insulinoma-associated 1
chr6_+_15185456 9.679 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr17_+_72918298 9.422 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr10_+_80150448 9.351 ENSMUST00000153477.1
Midn
midnolin
chr2_-_18048347 9.255 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr8_+_45628176 9.214 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr4_+_116221590 8.880 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr9_-_72111755 8.874 ENSMUST00000183492.1
ENSMUST00000184523.1
ENSMUST00000034755.6
Tcf12


transcription factor 12


chr1_+_66322102 8.789 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr14_+_31019159 8.775 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr7_+_45215753 8.700 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr1_-_64122256 8.694 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr15_+_25622525 8.692 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr2_+_124610573 8.627 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr2_+_68861564 8.567 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr1_-_139377094 8.563 ENSMUST00000131586.1
ENSMUST00000145244.1
Crb1

crumbs homolog 1 (Drosophila)

chr1_+_133246092 8.473 ENSMUST00000038295.8
ENSMUST00000105082.2
Plekha6

pleckstrin homology domain containing, family A member 6

chr3_-_108402589 8.428 ENSMUST00000147565.1
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr17_-_35704574 8.392 ENSMUST00000117301.1
ENSMUST00000134995.1
Ddr1

discoidin domain receptor family, member 1

chr5_+_75574916 8.355 ENSMUST00000144270.1
ENSMUST00000005815.6
Kit

kit oncogene

chr4_-_32923455 8.307 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr1_-_12991109 8.202 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr17_-_35697971 8.173 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr14_+_31019183 8.144 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr17_-_56476462 8.093 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chr1_+_6730135 8.036 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr4_+_9269285 8.017 ENSMUST00000038841.7
Clvs1
clavesin 1
chr4_-_20778527 8.002 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr9_-_75409951 7.945 ENSMUST00000049355.10
Mapk6
mitogen-activated protein kinase 6
chr2_-_84775420 7.871 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_-_115846080 7.799 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr11_-_19018956 7.776 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr7_+_112679327 7.748 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr7_-_37769624 7.706 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr6_-_38875965 7.669 ENSMUST00000160360.1
Hipk2
homeodomain interacting protein kinase 2
chr8_+_34807287 7.643 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr14_+_73237891 7.630 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr13_-_97747399 7.460 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_+_135584773 7.419 ENSMUST00000067468.4
Gm4793
predicted gene 4793
chr3_+_102010138 7.409 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr12_-_101028983 7.309 ENSMUST00000068411.3
ENSMUST00000085096.3
Ccdc88c

coiled-coil domain containing 88C

chr19_-_30175414 7.299 ENSMUST00000025778.7
Gldc
glycine decarboxylase
chr9_+_74976096 7.270 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr7_-_103853199 7.259 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr9_-_72111827 7.235 ENSMUST00000183404.1
ENSMUST00000184783.1
Tcf12

transcription factor 12

chr5_-_112228934 7.214 ENSMUST00000181535.2
Miat
myocardial infarction associated transcript (non-protein coding)
chr6_+_65042575 7.202 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr9_-_72111651 7.146 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr10_+_80151154 7.129 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr3_-_84040151 7.033 ENSMUST00000052342.7
D930015E06Rik
RIKEN cDNA D930015E06 gene
chr12_-_34528844 6.991 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr3_+_131110350 6.817 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr14_+_60378242 6.811 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr2_-_18048784 6.771 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr14_+_31019125 6.753 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr2_+_155381808 6.734 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr8_+_94977101 6.696 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr18_-_46212595 6.679 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr2_+_102706356 6.653 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr2_-_151973387 6.637 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr2_-_51149100 6.636 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr4_+_116221689 6.622 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr19_-_4334001 6.613 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr4_-_82705735 6.610 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr5_-_124352233 6.557 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr12_+_76072016 6.546 ENSMUST00000131480.1
Syne2
spectrin repeat containing, nuclear envelope 2
chr9_-_50727921 6.543 ENSMUST00000118707.1
ENSMUST00000034566.8
Dixdc1

DIX domain containing 1

chr17_-_35701937 6.518 ENSMUST00000155628.1
Ddr1
discoidin domain receptor family, member 1
chr8_-_122699066 6.480 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr9_+_109095427 6.433 ENSMUST00000072093.6
Plxnb1
plexin B1
chr17_+_80944611 6.417 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr10_-_60831571 6.376 ENSMUST00000077925.5
Unc5b
unc-5 homolog B (C. elegans)
chr11_+_78301529 6.359 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr11_-_90638062 6.358 ENSMUST00000020858.7
ENSMUST00000107875.1
ENSMUST00000107872.1
ENSMUST00000143203.1
Stxbp4



syntaxin binding protein 4



chr18_-_84086379 6.324 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr10_-_29144194 6.320 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr11_-_96005872 6.311 ENSMUST00000013559.2
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr1_+_62703667 6.301 ENSMUST00000114155.1
ENSMUST00000027112.6
ENSMUST00000063594.6
ENSMUST00000114157.2
Nrp2



neuropilin 2



chr12_+_24708984 6.273 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr1_-_182019927 6.268 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
Enah




enabled homolog (Drosophila)




chrX_-_143933204 6.242 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr5_-_44099220 6.231 ENSMUST00000165909.1
Prom1
prominin 1
chr3_+_88615367 6.211 ENSMUST00000176539.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr9_+_119402444 6.200 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr10_+_79996479 6.188 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr5_-_131538687 6.175 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr4_-_135272798 6.138 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr2_-_79456750 6.110 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr11_-_19018714 6.101 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr18_-_88927447 6.092 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr2_-_151973840 6.087 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr15_-_39943963 6.068 ENSMUST00000110305.2
Lrp12
low density lipoprotein-related protein 12
chr2_-_160367057 6.029 ENSMUST00000099126.3
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr9_-_75409352 6.020 ENSMUST00000168937.1
Mapk6
mitogen-activated protein kinase 6
chr17_+_43801823 5.970 ENSMUST00000044895.5
Rcan2
regulator of calcineurin 2
chr9_-_50728067 5.899 ENSMUST00000117646.1
Dixdc1
DIX domain containing 1
chr15_-_91049823 5.878 ENSMUST00000088614.5
ENSMUST00000100304.4
ENSMUST00000067205.8
ENSMUST00000109288.2
ENSMUST00000109287.2
Kif21a




kinesin family member 21A




chr3_-_38484831 5.854 ENSMUST00000120875.1
Ankrd50
ankyrin repeat domain 50
chr7_+_75643223 5.844 ENSMUST00000137959.1
Akap13
A kinase (PRKA) anchor protein 13
chr2_+_155382186 5.834 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr6_+_128375456 5.754 ENSMUST00000100926.2
4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr7_+_100493337 5.729 ENSMUST00000126534.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr10_+_29143996 5.701 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr4_-_34882919 5.697 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr12_-_54986328 5.666 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr6_+_83137089 5.643 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr13_-_95618442 5.604 ENSMUST00000059193.5
F2r
coagulation factor II (thrombin) receptor
chr7_-_105787544 5.586 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr15_-_84855093 5.585 ENSMUST00000016768.5
Phf21b
PHD finger protein 21B
chr2_+_52857844 5.574 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
Fmnl2


formin-like 2


chr18_-_47368446 5.573 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr17_+_35866056 5.551 ENSMUST00000122899.1
Ppp1r18
protein phosphatase 1, regulatory subunit 18
chr18_+_82914632 5.501 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr11_+_3289168 5.460 ENSMUST00000134089.1
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr17_-_29007925 5.454 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr4_+_59626189 5.453 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr4_-_155043143 5.442 ENSMUST00000135665.2
Plch2
phospholipase C, eta 2
chrX_+_38189829 5.426 ENSMUST00000131124.1
Zbtb33
zinc finger and BTB domain containing 33
chr2_+_15055274 5.407 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr13_-_54687644 5.387 ENSMUST00000129881.1
Rnf44
ring finger protein 44
chr17_+_52602700 5.298 ENSMUST00000039366.10
Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr17_-_70851189 5.276 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr4_+_48585276 5.264 ENSMUST00000123476.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr8_+_70863127 5.241 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr1_+_153749496 5.208 ENSMUST00000182722.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr4_+_116221633 5.185 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr2_-_60125651 5.162 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr1_-_55226768 5.157 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr5_+_90931196 5.148 ENSMUST00000071652.4
Mthfd2l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr13_-_97747373 5.132 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr12_+_80790532 5.125 ENSMUST00000068519.5
4933426M11Rik
RIKEN cDNA 4933426M11 gene
chr2_+_68861433 5.094 ENSMUST00000028426.2
Cers6
ceramide synthase 6
chr8_-_122678072 5.093 ENSMUST00000006525.7
ENSMUST00000064674.6
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr9_-_122903102 5.086 ENSMUST00000180877.1
ENSMUST00000180486.1
A530083I20Rik

RIKEN cDNA A530083I20 gene

chr12_-_54986363 5.081 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr2_+_156840966 5.076 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr13_-_8858762 5.069 ENSMUST00000176329.1
Wdr37
WD repeat domain 37
chr14_+_14703025 5.042 ENSMUST00000057015.6
Slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr15_-_79658749 5.023 ENSMUST00000109646.2
Fam227a
family with sequence similarity 227, member A
chr14_+_25607797 5.022 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr6_-_42693030 5.016 ENSMUST00000045140.4
Fam115a
family with sequence similarity 115, member A
chr14_+_59201418 5.013 ENSMUST00000140136.2
ENSMUST00000142326.1
Rcbtb1

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

chr14_-_62456286 5.007 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr9_+_102718424 5.005 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chrX_-_12128350 4.997 ENSMUST00000123004.1
Bcor
BCL6 interacting corepressor
chr2_-_130839683 4.973 ENSMUST00000119422.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr9_+_108826320 4.959 ENSMUST00000024238.5
Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr4_-_110290884 4.940 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr4_-_148130678 4.912 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr2_+_126552407 4.909 ENSMUST00000061491.7
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr9_+_58134535 4.906 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr9_-_58313189 4.906 ENSMUST00000061799.8
Loxl1
lysyl oxidase-like 1
chr16_+_20097554 4.881 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr5_-_50058908 4.852 ENSMUST00000030971.5
Gpr125
G protein-coupled receptor 125
chr6_-_86733218 4.846 ENSMUST00000113679.1
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr11_+_62077018 4.843 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr17_+_43667389 4.816 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr12_+_24708241 4.813 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr9_+_45430293 4.795 ENSMUST00000034592.8
Dscaml1
Down syndrome cell adhesion molecule like 1
chr3_+_88621436 4.740 ENSMUST00000170653.2
ENSMUST00000177303.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr18_+_64340225 4.719 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr11_+_3649759 4.714 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr7_+_112679314 4.694 ENSMUST00000084705.5
ENSMUST00000059768.10
Tead1

TEA domain family member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.7 32.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
7.9 23.7 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
5.1 55.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
4.8 24.0 GO:0035262 gonad morphogenesis(GO:0035262)
3.9 46.5 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
3.7 3.7 GO:0009786 regulation of asymmetric cell division(GO:0009786)
3.4 41.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
3.2 12.8 GO:0090235 regulation of metaphase plate congression(GO:0090235)
3.2 19.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
3.2 15.8 GO:0031022 nuclear migration along microfilament(GO:0031022)
3.2 6.3 GO:0060023 soft palate development(GO:0060023)
2.9 8.8 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
2.8 8.4 GO:1904347 intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770)
2.6 7.9 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
2.6 12.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
2.5 2.5 GO:1904412 regulation of cardiac ventricle development(GO:1904412)
2.5 27.7 GO:0060539 diaphragm development(GO:0060539)
2.5 10.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
2.4 7.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
2.4 9.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
2.4 9.7 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
2.4 9.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
2.3 35.0 GO:0046548 retinal rod cell development(GO:0046548)
2.2 35.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.1 6.4 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
2.1 8.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
2.1 6.3 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
2.1 6.2 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
2.1 6.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.0 6.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
2.0 4.1 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
2.0 10.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
2.0 2.0 GO:0070841 inclusion body assembly(GO:0070841) regulation of inclusion body assembly(GO:0090083)
2.0 12.1 GO:0003383 apical constriction(GO:0003383)
2.0 10.0 GO:0015671 oxygen transport(GO:0015671)
2.0 7.9 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
1.9 3.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
1.9 7.6 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
1.9 9.4 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
1.9 5.6 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
1.8 9.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.8 41.2 GO:0048368 lateral mesoderm development(GO:0048368)
1.7 6.8 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
1.7 8.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
1.7 13.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.7 9.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.7 11.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
1.7 6.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.6 4.9 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
1.6 4.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
1.6 8.1 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
1.6 6.5 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
1.6 6.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.6 6.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
1.6 6.2 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.5 6.2 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
1.5 12.1 GO:1990845 adaptive thermogenesis(GO:1990845)
1.5 16.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.5 6.0 GO:0021603 cranial nerve formation(GO:0021603)
1.5 4.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.5 19.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.4 4.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
1.4 4.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
1.4 12.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
1.4 6.8 GO:0007403 glial cell fate determination(GO:0007403)
1.3 22.9 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
1.3 4.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.3 3.9 GO:0043587 tongue morphogenesis(GO:0043587) fungiform papilla development(GO:0061196) fungiform papilla morphogenesis(GO:0061197)
1.3 5.1 GO:0006547 histidine metabolic process(GO:0006547)
1.3 5.0 GO:0046666 retinal cell programmed cell death(GO:0046666)
1.2 12.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
1.2 3.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
1.2 4.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.2 10.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
1.1 8.8 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
1.1 12.9 GO:0070932 histone H3 deacetylation(GO:0070932)
1.1 5.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
1.1 6.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.0 3.1 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
1.0 2.0 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.0 3.0 GO:0035973 aggrephagy(GO:0035973)
1.0 3.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
1.0 5.1 GO:0051684 maintenance of Golgi location(GO:0051684)
1.0 2.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
1.0 5.0 GO:0046684 response to pyrethroid(GO:0046684)
1.0 5.8 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.0 8.7 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
1.0 3.9 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.0 1.9 GO:0072553 terminal button organization(GO:0072553)
1.0 6.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.9 6.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.9 6.6 GO:0007296 vitellogenesis(GO:0007296)
0.9 7.3 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.9 2.7 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.9 3.6 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.9 13.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.9 5.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.9 4.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.9 2.6 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.9 2.6 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.9 2.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.9 2.6 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.9 6.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.8 1.7 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.8 4.2 GO:0046208 spermine catabolic process(GO:0046208)
0.8 3.4 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.8 5.8 GO:0033227 dsRNA transport(GO:0033227)
0.8 5.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.8 2.5 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.8 2.4 GO:1903334 positive regulation of protein folding(GO:1903334)
0.8 4.8 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.8 3.2 GO:0046898 response to cycloheximide(GO:0046898)
0.8 2.4 GO:0021972 corticospinal neuron axon guidance(GO:0021966) corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.8 2.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.8 2.3 GO:0007525 somatic muscle development(GO:0007525)
0.8 6.2 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.7 2.9 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.7 3.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.7 4.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.7 2.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.7 4.2 GO:0072697 protein localization to cell cortex(GO:0072697)
0.7 11.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.7 12.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.7 4.2 GO:0051013 microtubule severing(GO:0051013)
0.7 2.8 GO:0001880 Mullerian duct regression(GO:0001880)
0.7 2.8 GO:0010288 response to lead ion(GO:0010288)
0.7 2.0 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.7 12.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.7 12.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.7 10.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.7 12.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.7 2.0 GO:1990927 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.7 5.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.6 1.9 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.6 21.9 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.6 3.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.6 8.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.6 3.8 GO:0060017 parathyroid gland development(GO:0060017)
0.6 2.5 GO:0051133 regulation of NK T cell activation(GO:0051133) positive regulation of NK T cell activation(GO:0051135)
0.6 4.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6 4.8 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.6 10.6 GO:0060009 Sertoli cell development(GO:0060009)
0.6 9.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.6 4.0 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.6 8.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.6 1.7 GO:0003162 atrioventricular node development(GO:0003162)
0.6 4.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.6 2.8 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.5 7.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.5 4.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.5 3.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.5 4.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 4.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.5 1.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.5 2.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.5 2.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.5 1.5 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.5 2.6 GO:0006868 glutamine transport(GO:0006868)
0.5 1.5 GO:0045658 eosinophil differentiation(GO:0030222) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.5 4.6 GO:0015838 amino-acid betaine transport(GO:0015838)
0.5 2.5 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.5 1.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.5 4.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.5 9.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.5 11.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.5 4.8 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.5 2.4 GO:0061511 centriole elongation(GO:0061511)
0.5 1.9 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.5 5.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.5 3.2 GO:0050832 defense response to fungus(GO:0050832)
0.4 1.7 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 1.3 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.4 6.0 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 3.8 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.4 1.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 0.4 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.4 2.0 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.4 4.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 1.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.4 1.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.4 1.8 GO:0098543 detection of bacterium(GO:0016045) detection of molecule of bacterial origin(GO:0032490) detection of other organism(GO:0098543)
0.4 1.1 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.4 2.2 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.4 2.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.4 1.4 GO:0070307 lens fiber cell development(GO:0070307)
0.4 8.3 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.4 1.1 GO:0016598 protein arginylation(GO:0016598)
0.4 1.8 GO:0072718 response to cisplatin(GO:0072718)
0.4 9.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.3 1.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 1.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.3 3.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 2.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.3 3.7 GO:0006020 inositol metabolic process(GO:0006020)
0.3 2.4 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.3 1.7 GO:0060178 regulation of exocyst localization(GO:0060178)
0.3 2.7 GO:0006265 DNA topological change(GO:0006265)
0.3 1.0 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.3 2.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.0 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.3 0.3 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.3 3.0 GO:0030238 male sex determination(GO:0030238)
0.3 4.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.3 4.6 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.3 1.6 GO:0051012 microtubule sliding(GO:0051012)
0.3 13.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 0.3 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3 1.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.3 0.9 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.3 1.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3 3.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 5.9 GO:0070207 protein homotrimerization(GO:0070207)
0.3 1.5 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.3 6.5 GO:0007340 acrosome reaction(GO:0007340)
0.3 3.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3 7.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 6.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.3 5.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.3 3.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.3 2.0 GO:0045176 apical protein localization(GO:0045176)
0.3 2.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 3.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 0.5 GO:1902022 L-lysine transport(GO:1902022)
0.3 1.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.3 1.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 2.7 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.3 0.8 GO:1990859 cellular response to endothelin(GO:1990859)
0.3 4.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.3 2.3 GO:1902414 protein localization to cell junction(GO:1902414)
0.3 1.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 1.8 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.3 3.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.3 0.5 GO:2000646 negative regulation of PERK-mediated unfolded protein response(GO:1903898) positive regulation of receptor catabolic process(GO:2000646)
0.3 1.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 1.8 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.3 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.5 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.2 1.7 GO:0090091 microspike assembly(GO:0030035) regulation of microvillus assembly(GO:0032534) positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 1.5 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 5.6 GO:0007035 vacuolar acidification(GO:0007035)
0.2 1.0 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.2 6.9 GO:0035329 hippo signaling(GO:0035329)
0.2 2.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 8.6 GO:0007520 myoblast fusion(GO:0007520)
0.2 0.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 4.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 3.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 4.7 GO:0009749 response to glucose(GO:0009749)
0.2 0.9 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.2 3.8 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 1.2 GO:0006004 fucose metabolic process(GO:0006004)
0.2 1.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 0.7 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.2 1.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 1.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 5.5 GO:0009409 response to cold(GO:0009409)
0.2 3.7 GO:0008209 androgen metabolic process(GO:0008209)
0.2 2.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 1.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 2.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.2 11.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.2 1.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.2 1.9 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2 0.6 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 7.3 GO:0031648 protein destabilization(GO:0031648)
0.2 1.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.2 8.3 GO:1901998 toxin transport(GO:1901998)
0.2 1.9 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2 1.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 16.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 1.8 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 1.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 0.8 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 1.6 GO:0031639 plasminogen activation(GO:0031639)
0.2 13.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 2.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.2 3.6 GO:0060384 innervation(GO:0060384)
0.2 1.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.2 0.6 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.2 0.7 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.2 0.7 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 1.3 GO:0072176 nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
0.2 3.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 2.4 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.2 2.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 0.7 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.2 2.0 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819)
0.2 2.9 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 1.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 7.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 1.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 1.6 GO:0009301 snRNA transcription(GO:0009301)
0.2 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 2.9 GO:0001967 suckling behavior(GO:0001967)
0.2 6.2 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.2 5.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.8 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 5.1 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 0.5 GO:0060295 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) photoreceptor cell morphogenesis(GO:0008594) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.2 0.7 GO:0003266 regulation of secondary heart field cardioblast proliferation(GO:0003266) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 1.7 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 3.3 GO:0016180 snRNA processing(GO:0016180)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 2.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 1.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 1.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.3 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 7.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 2.4 GO:0050821 protein stabilization(GO:0050821)
0.1 1.9 GO:0021535 cell migration in hindbrain(GO:0021535)
0.1 7.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.5 GO:0090282 trophectodermal cell proliferation(GO:0001834) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.1 1.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 2.7 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 1.4 GO:0006012 galactose metabolic process(GO:0006012)
0.1 5.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.5 GO:1904526 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.1 5.4 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1 0.4 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 0.2 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 1.9 GO:0009299 mRNA transcription(GO:0009299)
0.1 0.4 GO:0051295 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) establishment of meiotic spindle localization(GO:0051295) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.6 GO:0098705 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.1 0.6 GO:0033762 response to glucagon(GO:0033762)
0.1 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.7 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 2.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 8.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 3.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.3 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 3.2 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 1.0 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 7.9 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 0.3 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 1.4 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148)
0.1 2.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.7 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.1 3.3 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.7 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.7 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1 1.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.7 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.8 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.7 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.8 GO:0061037 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037)
0.1 0.4 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 2.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.3 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.1 0.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 2.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593) negative regulation of lamellipodium organization(GO:1902744)
0.1 1.1 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.1 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.1 4.9 GO:0006986 response to unfolded protein(GO:0006986)
0.1 0.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 1.1 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 2.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.2 GO:0019319 hexose biosynthetic process(GO:0019319)
0.1 0.2 GO:0090190 positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 2.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.1 1.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 3.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.5 GO:0015074 DNA integration(GO:0015074)
0.1 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 2.1 GO:0006739 NADP metabolic process(GO:0006739)
0.1 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 1.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 1.6 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 2.7 GO:0051289 protein homotetramerization(GO:0051289)
0.1 0.3 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 0.9 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.4 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.1 0.7 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 6.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 1.1 GO:0001825 blastocyst formation(GO:0001825)
0.0 2.5 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 6.1 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 3.0 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 1.1 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.0 GO:0001824 blastocyst development(GO:0001824)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0090646 mitochondrial RNA 3'-end processing(GO:0000965) tRNA 3'-end processing(GO:0042780) mitochondrial tRNA processing(GO:0090646)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.0 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 2.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.5 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 2.6 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 2.2 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.7 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0002076 osteoblast development(GO:0002076)
0.0 0.8 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.4 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.3 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.0 0.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 24.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
4.1 12.4 GO:0071148 TEAD-1-YAP complex(GO:0071148)
2.7 10.7 GO:0008623 CHRAC(GO:0008623)
2.2 11.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
2.1 6.2 GO:0071914 prominosome(GO:0071914)
2.1 18.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
2.0 15.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.8 8.8 GO:0036449 microtubule minus-end(GO:0036449)
1.7 6.8 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
1.7 6.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.6 6.3 GO:0044307 dendritic branch(GO:0044307)
1.4 11.3 GO:0033269 internode region of axon(GO:0033269)
1.4 4.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
1.3 7.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
1.3 10.0 GO:0005833 hemoglobin complex(GO:0005833)
1.2 16.3 GO:0016342 catenin complex(GO:0016342)
1.1 4.5 GO:0099569 presynaptic cytoskeleton(GO:0099569)
1.0 3.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.0 3.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.0 16.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.9 5.6 GO:0031094 platelet dense tubular network(GO:0031094)
0.9 21.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.9 8.1 GO:0030478 actin cap(GO:0030478)
0.9 2.7 GO:0030905 retromer, tubulation complex(GO:0030905)
0.9 5.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.8 2.5 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.8 15.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.8 15.0 GO:0035102 PRC1 complex(GO:0035102)
0.8 4.8 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.8 6.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.7 2.1 GO:1990047 spindle matrix(GO:1990047)
0.7 2.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.7 2.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.7 2.7 GO:0001651 dense fibrillar component(GO:0001651)
0.7 9.3 GO:0042788 polysomal ribosome(GO:0042788)
0.7 7.8 GO:0043596 nuclear replication fork(GO:0043596)
0.6 6.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.6 5.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.6 4.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.6 2.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.6 5.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.6 3.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.5 2.1 GO:0008537 proteasome activator complex(GO:0008537)
0.5 12.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.5 5.1 GO:0070545 PeBoW complex(GO:0070545)
0.5 1.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.5 19.6 GO:0002102 podosome(GO:0002102)
0.4 4.9 GO:0030057 desmosome(GO:0030057)
0.4 3.5 GO:0002177 manchette(GO:0002177)
0.4 8.2 GO:0001891 phagocytic cup(GO:0001891)
0.4 14.6 GO:0090544 BAF-type complex(GO:0090544)
0.4 3.8 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.4 6.8 GO:0036038 MKS complex(GO:0036038)
0.4 6.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.4 26.7 GO:0005871 kinesin complex(GO:0005871)
0.4 3.1 GO:0097413 Lewy body(GO:0097413)
0.4 1.5 GO:1902737 dendritic filopodium(GO:1902737)
0.4 1.5 GO:0001652 granular component(GO:0001652)
0.4 47.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.4 3.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.4 1.5 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 3.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.4 2.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 1.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 0.3 GO:0035101 FACT complex(GO:0035101)
0.3 57.5 GO:0032993 protein-DNA complex(GO:0032993)
0.3 1.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 5.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 1.7 GO:0061689 tricellular tight junction(GO:0061689)
0.3 6.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 3.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.3 7.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 1.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.3 27.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 1.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 6.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 1.2 GO:0097165 nuclear stress granule(GO:0097165)
0.3 4.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 3.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 11.0 GO:1990391 DNA repair complex(GO:1990391)
0.3 3.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.3 1.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 3.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 5.2 GO:0000145 exocyst(GO:0000145)
0.3 4.6 GO:0016580 Sin3 complex(GO:0016580)
0.3 2.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 4.3 GO:0034399 nuclear periphery(GO:0034399)
0.3 8.2 GO:0031519 PcG protein complex(GO:0031519)
0.3 1.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 16.7 GO:0016459 myosin complex(GO:0016459)
0.3 0.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.3 1.6 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 16.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 4.7 GO:0031430 M band(GO:0031430)
0.2 13.8 GO:0030427 site of polarized growth(GO:0030427)
0.2 60.8 GO:0005667 transcription factor complex(GO:0005667)
0.2 1.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 3.8 GO:0032039 integrator complex(GO:0032039)
0.2 0.7 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 21.1 GO:0016363 nuclear matrix(GO:0016363)
0.2 8.0 GO:0001772 immunological synapse(GO:0001772)
0.2 8.7 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 23.0 GO:0070160 occluding junction(GO:0070160)
0.2 2.3 GO:0070938 contractile ring(GO:0070938)
0.2 0.6 GO:0031251 PAN complex(GO:0031251)
0.2 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 3.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 3.0 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.2 6.0 GO:0072562 blood microparticle(GO:0072562)
0.2 5.1 GO:0016592 mediator complex(GO:0016592)
0.2 1.9 GO:0045180 basal cortex(GO:0045180)
0.2 3.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.2 7.0 GO:0042641 actomyosin(GO:0042641)
0.2 2.2 GO:0098862 cluster of actin-based cell projections(GO:0098862)
0.2 6.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 1.2 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.0 GO:0071437 invadopodium(GO:0071437)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 2.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 1.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 10.7 GO:0005776 autophagosome(GO:0005776)
0.1 0.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.5 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 7.5 GO:0005902 microvillus(GO:0005902)
0.1 11.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.1 1.4 GO:0097470 ribbon synapse(GO:0097470)
0.1 22.0 GO:0005815 microtubule organizing center(GO:0005815)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 2.5 GO:0034704 calcium channel complex(GO:0034704)
0.1 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.3 GO:0044326 dendritic spine neck(GO:0044326)
0.1 25.5 GO:0043235 receptor complex(GO:0043235)
0.1 1.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 6.4 GO:0014069 postsynaptic density(GO:0014069)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 3.9 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.5 GO:0097443 sorting endosome(GO:0097443)
0.1 0.8 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.1 3.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.5 GO:0005876 spindle microtubule(GO:0005876)
0.1 4.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.1 GO:0008021 synaptic vesicle(GO:0008021)
0.1 4.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 5.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 4.2 GO:0005903 brush border(GO:0005903)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.8 GO:0031941 filamentous actin(GO:0031941)
0.1 3.2 GO:0005844 polysome(GO:0005844)
0.1 0.3 GO:0060091 kinocilium(GO:0060091)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 4.1 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 1.3 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 5.0 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 0.3 GO:0000322 storage vacuole(GO:0000322)
0.1 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.3 GO:0005921 gap junction(GO:0005921)
0.1 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 5.8 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 2.6 GO:0030880 RNA polymerase complex(GO:0030880)
0.0 50.0 GO:0005794 Golgi apparatus(GO:0005794)
0.0 3.3 GO:0005814 centriole(GO:0005814)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 63.8 GO:0005654 nucleoplasm(GO:0005654)
0.0 2.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 23.2 GO:0005730 nucleolus(GO:0005730)
0.0 0.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 4.6 GO:0030424 axon(GO:0030424)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 4.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 86.1 GO:0005634 nucleus(GO:0005634)
0.0 3.0 GO:0005929 cilium(GO:0005929)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 47.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
3.0 12.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
3.0 20.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
2.5 7.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.4 19.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
2.3 6.8 GO:0005118 sevenless binding(GO:0005118)
2.2 11.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.2 8.7 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
2.1 6.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
2.0 10.0 GO:0005344 oxygen transporter activity(GO:0005344)
1.9 7.6 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
1.9 36.1 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
1.8 5.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
1.8 12.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.7 5.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
1.6 24.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
1.6 3.2 GO:0070644 vitamin D response element binding(GO:0070644)
1.5 12.3 GO:0046790 virion binding(GO:0046790)
1.5 13.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
1.4 4.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
1.4 11.0 GO:0050693 LBD domain binding(GO:0050693)
1.4 5.5 GO:0038025 reelin receptor activity(GO:0038025)
1.4 4.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.3 4.0 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
1.2 23.3 GO:0035497 cAMP response element binding(GO:0035497)
1.1 6.8 GO:0030284 estrogen receptor activity(GO:0030284)
1.1 6.6 GO:0045322 unmethylated CpG binding(GO:0045322)
1.1 4.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
1.1 6.4 GO:0005042 netrin receptor activity(GO:0005042)
1.0 8.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
1.0 4.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.0 8.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.0 6.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.0 19.8 GO:0030215 semaphorin receptor binding(GO:0030215)
1.0 3.9 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
1.0 6.8 GO:0070087 DNA translocase activity(GO:0015616) chromo shadow domain binding(GO:0070087)
1.0 8.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.0 4.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.9 5.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.9 3.7 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.9 2.8 GO:0008527 taste receptor activity(GO:0008527)
0.9 14.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.9 12.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.9 2.7 GO:0030350 iron-responsive element binding(GO:0030350)
0.9 6.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.9 5.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.9 48.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.9 2.6 GO:0005124 scavenger receptor binding(GO:0005124)
0.8 2.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.8 2.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.8 2.5 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.8 4.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.8 10.5 GO:0005522 profilin binding(GO:0005522)
0.8 4.8 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.8 13.5 GO:0070410 co-SMAD binding(GO:0070410)
0.8 3.0 GO:0043426 MRF binding(GO:0043426)
0.7 8.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.7 3.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.7 3.7 GO:0005113 patched binding(GO:0005113)
0.7 3.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.7 4.1 GO:0097016 L27 domain binding(GO:0097016)
0.7 20.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.7 2.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.7 8.7 GO:0030957 Tat protein binding(GO:0030957)
0.7 2.7 GO:0097100 supercoiled DNA binding(GO:0097100)
0.7 2.7 GO:1990460 leptin receptor binding(GO:1990460)
0.7 38.4 GO:0030507 spectrin binding(GO:0030507)
0.7 8.5 GO:0043495 protein anchor(GO:0043495)
0.6 1.9 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.6 8.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.6 4.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.6 3.6 GO:0001972 retinoic acid binding(GO:0001972)
0.6 4.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.6 1.7 GO:0071723 lipopeptide binding(GO:0071723)
0.6 1.7 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.6 6.2 GO:0048185 activin binding(GO:0048185)
0.6 2.8 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.5 3.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.5 1.6 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.5 16.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5 13.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.5 2.1 GO:0050436 microfibril binding(GO:0050436)
0.5 2.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.5 9.2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.5 3.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.5 1.5 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.5 1.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.5 4.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.5 2.4 GO:0070051 fibrinogen binding(GO:0070051)
0.5 1.4 GO:0004335 galactokinase activity(GO:0004335)
0.5 7.8 GO:0004707 MAP kinase activity(GO:0004707)
0.5 5.9 GO:0070513 death domain binding(GO:0070513)
0.5 4.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.4 3.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.4 1.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 1.7 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.4 2.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 1.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.4 7.9 GO:0001848 complement binding(GO:0001848)
0.4 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 2.8 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.4 26.6 GO:0003777 microtubule motor activity(GO:0003777)
0.4 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.4 7.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.4 3.8 GO:0031996 thioesterase binding(GO:0031996)
0.4 16.5 GO:0030332 cyclin binding(GO:0030332)
0.4 8.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.4 3.7 GO:0001727 lipid kinase activity(GO:0001727)
0.4 24.7 GO:0035064 methylated histone binding(GO:0035064)
0.4 6.2 GO:0042805 actinin binding(GO:0042805)
0.4 3.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.4 10.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 2.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.4 2.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 5.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 2.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3 4.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.3 1.4 GO:0003883 CTP synthase activity(GO:0003883)
0.3 6.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 2.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.3 6.7 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.3 18.4 GO:0035326 enhancer binding(GO:0035326)
0.3 2.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 6.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 1.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 0.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 1.5 GO:0043559 insulin binding(GO:0043559)
0.3 10.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 5.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 1.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.3 0.9 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.3 6.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 2.4 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.3 5.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 2.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.3 5.0 GO:0017166 vinculin binding(GO:0017166)
0.3 10.5 GO:0017091 AU-rich element binding(GO:0017091)
0.3 8.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 2.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 9.2 GO:0045182 translation regulator activity(GO:0045182)
0.3 5.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 2.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 1.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 1.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.3 6.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 4.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 0.7 GO:0030492 hemoglobin binding(GO:0030492)
0.2 2.4 GO:0070097 delta-catenin binding(GO:0070097)
0.2 5.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.2 51.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 9.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 2.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 8.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 3.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 5.4 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 1.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 0.6 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.2 0.6 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 2.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 3.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 31.6 GO:0001047 core promoter binding(GO:0001047)
0.2 1.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 2.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 3.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 2.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 30.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 2.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 4.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 9.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 5.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 0.7 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 3.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 3.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 5.3 GO:0042169 SH2 domain binding(GO:0042169)
0.2 5.6 GO:0005109 frizzled binding(GO:0005109)
0.2 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.4 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 10.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 4.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.2 1.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.2 0.5 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.1 3.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 9.0 GO:0019843 rRNA binding(GO:0019843)
0.1 0.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 2.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 11.2 GO:0003682 chromatin binding(GO:0003682)
0.1 0.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 11.1 GO:0043130 ubiquitin binding(GO:0043130)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 23.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 4.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.1 1.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.5 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 29.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 3.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 1.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 2.3 GO:0005112 Notch binding(GO:0005112)
0.1 3.2 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.1 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 3.3 GO:0002039 p53 binding(GO:0002039)
0.1 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 6.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.1 3.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 2.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 16.2 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 2.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 0.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 69.6 GO:0003677 DNA binding(GO:0003677)
0.1 0.6 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.1 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.1 0.2 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 10.3 GO:0008017 microtubule binding(GO:0008017)
0.1 0.2 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.1 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.9 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 1.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.1 GO:0051287 NAD binding(GO:0051287)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 2.6 GO:0005178 integrin binding(GO:0005178)
0.0 1.8 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 1.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 1.6 GO:0002020 protease binding(GO:0002020)
0.0 2.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 3.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 3.6 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 24.3 GO:0003723 RNA binding(GO:0003723)
0.0 0.8 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.3 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.7 30.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.7 38.5 PID_IL12_2PATHWAY IL12-mediated signaling events
0.6 6.1 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.6 6.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.5 6.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.5 6.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.5 6.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 6.6 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.5 7.0 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.5 17.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.5 5.6 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 12.0 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.4 17.3 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.4 10.7 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.4 9.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.3 15.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.3 0.7 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.3 2.8 PID_ALK2_PATHWAY ALK2 signaling events
0.3 11.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 5.2 PID_CD40_PATHWAY CD40/CD40L signaling
0.3 30.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.3 5.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 3.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.3 6.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 8.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.3 2.4 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.3 12.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 2.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.2 11.7 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.2 7.2 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.2 3.8 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.2 11.7 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.2 5.8 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.2 14.8 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.2 15.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.2 7.3 PID_ERBB4_PATHWAY ErbB4 signaling events
0.2 10.3 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.2 7.2 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.2 2.4 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.2 2.0 PID_FGF_PATHWAY FGF signaling pathway
0.2 9.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.2 2.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.2 0.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.2 13.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.2 8.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.2 8.2 PID_E2F_PATHWAY E2F transcription factor network
0.2 2.9 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 2.9 PID_FOXO_PATHWAY FoxO family signaling
0.1 1.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 2.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.2 PID_ALK1_PATHWAY ALK1 signaling events
0.1 3.8 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 4.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 2.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 5.2 PID_LKB1_PATHWAY LKB1 signaling events
0.1 5.6 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 10.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.0 PID_MYC_PATHWAY C-MYC pathway
0.1 1.8 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.1 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 1.0 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 7.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.9 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.4 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 1.5 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.4 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.1 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 20.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
1.2 9.7 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
1.2 35.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.1 6.7 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.8 7.6 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.8 17.3 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.8 6.5 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.8 10.8 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.7 18.5 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.7 8.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.6 6.5 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.6 16.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.6 12.1 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6 4.0 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.6 11.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.5 19.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.5 6.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 2.6 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.5 16.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.4 4.4 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.4 4.2 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.4 17.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.4 6.2 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.4 6.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.4 6.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.4 15.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.4 4.5 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.4 12.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.3 2.8 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.3 7.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.3 6.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 3.1 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.3 19.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.3 4.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.3 2.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.3 4.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 2.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 7.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 2.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 6.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 6.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.2 8.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 2.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 8.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 3.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 14.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 5.0 REACTOME_KINESINS Genes involved in Kinesins
0.2 3.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.2 4.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 2.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 2.3 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.2 1.1 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 2.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 1.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 1.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 14.0 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 3.7 REACTOME_MEIOSIS Genes involved in Meiosis
0.2 2.0 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.6 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 2.6 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 9.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.0 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 2.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.1 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 1.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 8.5 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.1 2.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 9.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 1.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.1 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 3.6 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 7.1 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 2.0 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 0.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 1.1 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.7 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 1.4 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.4 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 0.8 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.1 2.6 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 4.9 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.7 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 13.4 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.3 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.1 REACTOME_BIOLOGICAL_OXIDATIONS Genes involved in Biological oxidations
0.0 1.3 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 2.1 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 0.5 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.1 REACTOME_IL_2_SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism