Motif ID: Sox30

Z-value: 0.273


Transcription factors associated with Sox30:

Gene SymbolEntrez IDGene Name
Sox30 ENSMUSG00000040489.5 Sox30



Activity profile for motif Sox30.

activity profile for motif Sox30


Sorted Z-values histogram for motif Sox30

Sorted Z-values for motif Sox30



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox30

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 3.482 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr3_+_34649987 1.936 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr1_+_135729147 1.617 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr5_+_92809372 1.480 ENSMUST00000113054.2
 Shroom3
shroom family member 3
chr9_+_7764041 1.383 ENSMUST00000052865.9
 Tmem123
transmembrane protein 123
chr18_-_88927447 1.191 ENSMUST00000147313.1
 Socs6
suppressor of cytokine signaling 6
chrX_-_134161928 1.136 ENSMUST00000033611.4
 Xkrx
X Kell blood group precursor related X linked
chr12_-_99883429 1.112 ENSMUST00000046485.3
 Efcab11
EF-hand calcium binding domain 11
chr6_-_3494587 0.935 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr10_+_17796256 0.923 ENSMUST00000037964.6
 Txlnb
taxilin beta
chr9_-_103480328 0.892 ENSMUST00000124310.2
 Bfsp2
beaded filament structural protein 2, phakinin
chr18_-_62756275 0.756 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr9_-_72111651 0.689 ENSMUST00000185117.1
 Tcf12
transcription factor 12
chr14_+_116925379 0.607 ENSMUST00000088483.3
 Gpc6
glypican 6
chr10_-_62792243 0.607 ENSMUST00000020268.5
 Ccar1
cell division cycle and apoptosis regulator 1
chr13_-_97747373 0.547 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_101883010 0.505 ENSMUST00000154525.1
 Prr5l
proline rich 5 like
chr2_-_58052832 0.385 ENSMUST00000090940.5
 Ermn
ermin, ERM-like protein
chr1_+_37997975 0.384 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr13_-_56135629 0.369 ENSMUST00000016081.6
ENSMUST00000045788.7
 H2afy

H2A histone family, member Y

chr13_-_102958084 0.341 ENSMUST00000099202.3
ENSMUST00000172264.1
 Mast4

microtubule associated serine/threonine kinase family member 4

chr10_-_53647080 0.337 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr7_+_127800604 0.328 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
 Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr9_-_60511003 0.326 ENSMUST00000098660.3
 Thsd4
thrombospondin, type I, domain containing 4
chr14_-_19823807 0.320 ENSMUST00000022341.5
 2700060E02Rik
RIKEN cDNA 2700060E02 gene
chrX_+_56786527 0.299 ENSMUST00000144600.1
 Fhl1
four and a half LIM domains 1
chr4_+_137993445 0.286 ENSMUST00000105831.2
ENSMUST00000084214.5
 Eif4g3

eukaryotic translation initiation factor 4 gamma, 3

chr7_+_90426312 0.283 ENSMUST00000061391.7
 Ccdc89
coiled-coil domain containing 89
chr18_-_74961252 0.265 ENSMUST00000066532.4
 Lipg
lipase, endothelial
chr2_-_181599128 0.231 ENSMUST00000060173.8
 Samd10
sterile alpha motif domain containing 10
chr11_+_3983636 0.231 ENSMUST00000078757.1
 Gal3st1
galactose-3-O-sulfotransferase 1
chr2_-_119787504 0.229 ENSMUST00000110793.1
ENSMUST00000099529.2
ENSMUST00000048493.5
 Rpap1


RNA polymerase II associated protein 1


chr17_-_79355082 0.216 ENSMUST00000068958.7
 Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr11_+_3983704 0.214 ENSMUST00000063004.7
 Gal3st1
galactose-3-O-sulfotransferase 1
chr1_+_10056922 0.191 ENSMUST00000149214.1
 Cspp1
centrosome and spindle pole associated protein 1
chr19_+_44293676 0.165 ENSMUST00000026221.5
 Scd2
stearoyl-Coenzyme A desaturase 2
chr11_+_21091291 0.112 ENSMUST00000093290.5
 Peli1
pellino 1
chr4_+_109343029 0.109 ENSMUST00000030281.5
 Eps15
epidermal growth factor receptor pathway substrate 15
chr12_+_8674224 0.097 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr13_-_97747399 0.083 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_+_134396320 0.072 ENSMUST00000105869.2
 Pafah2
platelet-activating factor acetylhydrolase 2
chr4_+_137993016 0.068 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
 Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr15_+_100038635 0.068 ENSMUST00000100203.3
 Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr10_+_90829538 0.053 ENSMUST00000179694.2
 Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr3_-_8964037 0.052 ENSMUST00000091354.5
ENSMUST00000094381.4
 Tpd52

tumor protein D52

chr4_+_48585135 0.052 ENSMUST00000030032.6
 Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr12_+_8674129 0.050 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr5_-_17835857 0.049 ENSMUST00000082367.6
 Cd36
CD36 antigen
chr4_+_83417715 0.047 ENSMUST00000030206.3
ENSMUST00000071544.4
 Snapc3

small nuclear RNA activating complex, polypeptide 3

chr11_+_51261719 0.024 ENSMUST00000130641.1
 Clk4
CDC like kinase 4
chr19_-_24477356 0.023 ENSMUST00000099556.1
 Fam122a
family with sequence similarity 122, member A
chr3_-_127837419 0.002 ENSMUST00000051737.6
 Ap1ar
adaptor-related protein complex 1 associated regulatory protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.9 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.4 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.1 1.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.4 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 1.6 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.5 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0070543 response to linoleic acid(GO:0070543)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 1.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.1 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)
0.0 2.6 GO:0044798 nuclear transcription factor complex(GO:0044798)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 1.9 GO:0035198 miRNA binding(GO:0035198)
0.1 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.3 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism