Motif ID: Sox3_Sox10

Z-value: 1.587

Transcription factors associated with Sox3_Sox10:

Gene SymbolEntrez IDGene Name
Sox10 ENSMUSG00000033006.9 Sox10
Sox3 ENSMUSG00000045179.8 Sox3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox3mm10_v2_chrX_-_60893430_60893440-0.641.1e-07Click!
Sox10mm10_v2_chr15_-_79164477_79164496-0.256.8e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Sox3_Sox10

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_67586675 25.143 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr11_+_67586520 24.986 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr6_-_13839916 16.808 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr6_+_51432663 15.911 ENSMUST00000005103.5
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chrX_-_143933089 15.867 ENSMUST00000087313.3
Dcx
doublecortin
chr2_+_158666690 15.845 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr18_+_37484955 14.713 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr6_-_136171722 14.116 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr17_-_68004075 13.517 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr5_+_66968559 13.054 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr1_+_34579693 12.327 ENSMUST00000052670.8
Amer3
APC membrane recruitment 3
chrX_-_167209149 11.985 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr6_+_51432678 11.774 ENSMUST00000160133.1
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr1_+_66321708 11.495 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr10_-_29144194 11.007 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr17_+_55445550 10.667 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr4_+_102254739 10.477 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_+_66322102 10.286 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr2_-_64975762 10.172 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr12_-_31713873 10.113 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chr14_-_121698417 10.049 ENSMUST00000040700.7
Dock9
dedicator of cytokinesis 9
chr15_-_95528228 10.003 ENSMUST00000075275.2
Nell2
NEL-like 2
chr11_+_97415527 9.581 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr9_+_112234257 9.432 ENSMUST00000149308.3
ENSMUST00000144424.2
ENSMUST00000139552.2
2900079G21Rik


RIKEN cDNA 2900079G21 gene


chr16_-_76373014 9.397 ENSMUST00000054178.1
Nrip1
nuclear receptor interacting protein 1
chr5_+_66968416 9.306 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr1_-_134235420 9.148 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr13_-_14523178 9.072 ENSMUST00000110516.2
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr10_-_94035789 8.991 ENSMUST00000123201.1
ENSMUST00000119818.1
Vezt

vezatin, adherens junctions transmembrane protein

chr3_+_65109343 8.952 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr19_+_44992127 8.871 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr7_-_74013676 8.754 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr11_+_104231573 8.751 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chrX_-_143933204 8.558 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr2_+_65845833 8.548 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr11_+_104231515 8.439 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr2_-_119271202 8.380 ENSMUST00000037360.7
Rhov
ras homolog gene family, member V
chr7_-_47132698 8.283 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr5_+_148265202 8.182 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr9_-_75597643 8.180 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr5_-_34187670 8.179 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr18_+_37489465 8.121 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr16_+_13986596 8.108 ENSMUST00000056521.5
ENSMUST00000118412.1
ENSMUST00000131608.1
2900011O08Rik


RIKEN cDNA 2900011O08 gene


chr11_+_104231465 7.898 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr12_+_81631369 7.879 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr11_-_76468396 7.873 ENSMUST00000065028.7
Abr
active BCR-related gene
chr4_-_116405986 7.831 ENSMUST00000123072.1
ENSMUST00000144281.1
Mast2

microtubule associated serine/threonine kinase 2

chr7_+_29303938 7.770 ENSMUST00000108231.1
Dpf1
D4, zinc and double PHD fingers family 1
chr10_-_116473418 7.692 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr13_+_93304940 7.690 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
Homer1





homer homolog 1 (Drosophila)





chr7_+_29309429 7.608 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr11_+_104231390 7.525 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr14_-_79771305 7.516 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr7_+_29303958 7.515 ENSMUST00000049977.6
Dpf1
D4, zinc and double PHD fingers family 1
chr19_+_26623419 7.454 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_+_148265265 7.424 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr5_+_148265307 7.423 ENSMUST00000110514.1
Mtus2
microtubule associated tumor suppressor candidate 2
chr10_-_94035705 7.415 ENSMUST00000118077.1
ENSMUST00000118205.1
ENSMUST00000047711.6
Vezt


vezatin, adherens junctions transmembrane protein


chr5_-_8622855 7.394 ENSMUST00000047485.8
ENSMUST00000115378.1
Rundc3b

RUN domain containing 3B

chr5_+_26904682 7.387 ENSMUST00000120555.1
Dpp6
dipeptidylpeptidase 6
chr1_-_64122256 7.374 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr2_-_6722187 7.183 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr15_-_95528702 7.124 ENSMUST00000166170.1
Nell2
NEL-like 2
chr10_+_29143996 7.099 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr13_+_43615950 6.941 ENSMUST00000161817.1
Rnf182
ring finger protein 182
chr2_+_68117713 6.904 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_+_4559742 6.889 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr2_-_6721890 6.843 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr13_+_83504032 6.818 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr4_+_47208005 6.767 ENSMUST00000082303.6
ENSMUST00000102917.4
Col15a1

collagen, type XV, alpha 1

chr5_+_37245792 6.760 ENSMUST00000031004.7
Crmp1
collapsin response mediator protein 1
chr2_+_65845767 6.643 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr13_-_54749627 6.635 ENSMUST00000099506.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr18_-_43393346 6.592 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr3_-_122619663 6.566 ENSMUST00000162409.1
Fnbp1l
formin binding protein 1-like
chr10_+_80300997 6.555 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr6_+_17463749 6.553 ENSMUST00000115443.1
Met
met proto-oncogene
chr10_-_83533383 6.461 ENSMUST00000146640.1
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr12_+_109545390 6.394 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr10_-_83534130 6.387 ENSMUST00000020497.7
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr6_+_17065129 6.244 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr2_-_11502025 6.177 ENSMUST00000114846.2
Pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_-_72236692 6.085 ENSMUST00000021497.9
ENSMUST00000137990.1
Rtn1

reticulon 1

chr11_-_102296618 6.058 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr1_-_56972437 6.048 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr6_+_137252297 6.047 ENSMUST00000077115.6
ENSMUST00000167679.1
Ptpro

protein tyrosine phosphatase, receptor type, O

chr19_+_8664005 5.950 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr12_+_29528382 5.906 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr1_-_93101825 5.848 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr6_+_17491216 5.821 ENSMUST00000080469.5
Met
met proto-oncogene
chr10_+_43579161 5.784 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr2_-_6884940 5.714 ENSMUST00000183091.1
ENSMUST00000182851.1
Celf2

CUGBP, Elav-like family member 2

chr18_-_23038656 5.690 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr12_+_73997749 5.666 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr18_+_37294840 5.617 ENSMUST00000056522.3
Pcdhb2
protocadherin beta 2
chr4_-_141599835 5.580 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
Fblim1



filamin binding LIM protein 1



chr8_+_123411424 5.578 ENSMUST00000071134.3
Tubb3
tubulin, beta 3 class III
chr1_+_161142706 5.577 ENSMUST00000111608.1
ENSMUST00000052245.8
Ankrd45

ankyrin repeat domain 45

chr13_-_110280103 5.470 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chr7_-_142095266 5.467 ENSMUST00000039926.3
Dusp8
dual specificity phosphatase 8
chr18_-_43059418 5.467 ENSMUST00000025377.7
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr1_+_66386968 5.435 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr13_-_54749849 5.392 ENSMUST00000135343.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr2_-_11502090 5.362 ENSMUST00000179584.1
ENSMUST00000170196.2
ENSMUST00000171188.2
ENSMUST00000114845.3
ENSMUST00000114844.1
ENSMUST00000100411.2
Pfkfb3





6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3





chr4_+_43406435 5.358 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr8_-_84773381 5.347 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr18_-_61536522 5.314 ENSMUST00000171629.1
Arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr4_-_148130678 5.275 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr6_+_17463826 5.260 ENSMUST00000140070.1
Met
met proto-oncogene
chr1_-_25228814 5.175 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr2_-_65567465 5.135 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr16_-_30550560 5.123 ENSMUST00000140402.1
Tmem44
transmembrane protein 44
chr14_+_3412614 5.075 ENSMUST00000170123.1
Gm10409
predicted gene 10409
chr11_-_69560186 5.066 ENSMUST00000004036.5
Efnb3
ephrin B3
chr15_-_58214882 5.022 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr11_-_107794557 4.995 ENSMUST00000021066.3
Cacng4
calcium channel, voltage-dependent, gamma subunit 4
chr7_+_128688480 4.994 ENSMUST00000118605.1
Inpp5f
inositol polyphosphate-5-phosphatase F
chr2_-_65567505 4.988 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr13_+_93304799 4.942 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chr18_-_37020679 4.900 ENSMUST00000097612.2
Gm10545
predicted gene 10545
chr6_+_65671590 4.879 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr11_-_74590065 4.872 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr14_+_61138445 4.865 ENSMUST00000089394.3
ENSMUST00000119509.1
Sacs

sacsin

chr16_+_20097554 4.856 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr2_-_11502067 4.731 ENSMUST00000028114.6
ENSMUST00000049849.6
Pfkfb3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

chr11_-_98329641 4.680 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr11_+_42419729 4.659 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr2_+_32621750 4.652 ENSMUST00000113278.2
Ak1
adenylate kinase 1
chr17_-_35838259 4.628 ENSMUST00000001566.8
Tubb5
tubulin, beta 5 class I
chr7_+_82175156 4.624 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr4_+_116221590 4.621 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr10_+_60106198 4.607 ENSMUST00000121820.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr10_-_109010955 4.588 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr4_+_48049080 4.576 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr5_-_136244865 4.563 ENSMUST00000005188.9
Sh2b2
SH2B adaptor protein 2
chr7_+_82174796 4.559 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr16_+_17146937 4.539 ENSMUST00000115706.1
ENSMUST00000069064.4
Ydjc

YdjC homolog (bacterial)

chr7_+_96210107 4.533 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr2_-_52676571 4.514 ENSMUST00000178799.1
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr11_-_68957445 4.510 ENSMUST00000108671.1
Arhgef15
Rho guanine nucleotide exchange factor (GEF) 15
chr9_+_40269273 4.473 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr1_-_22805994 4.453 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr2_+_32625431 4.444 ENSMUST00000113277.1
Ak1
adenylate kinase 1
chr7_-_16874845 4.436 ENSMUST00000181501.1
9330104G04Rik
RIKEN cDNA 9330104G04 gene
chr9_+_40269202 4.429 ENSMUST00000114956.3
ENSMUST00000049941.5
Scn3b

sodium channel, voltage-gated, type III, beta

chr5_+_3928033 4.412 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr8_-_41054771 4.389 ENSMUST00000093534.4
Mtus1
mitochondrial tumor suppressor 1
chr18_+_37421418 4.373 ENSMUST00000053073.4
Pcdhb11
protocadherin beta 11
chr2_+_61804453 4.359 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr13_-_34130345 4.358 ENSMUST00000075774.3
Tubb2b
tubulin, beta 2B class IIB
chr13_+_109685994 4.319 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr17_+_52602700 4.306 ENSMUST00000039366.10
Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr5_+_137553517 4.281 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chrX_-_59568068 4.272 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr9_+_49518336 4.266 ENSMUST00000068730.3
Gm11149
predicted gene 11149
chr4_+_48585276 4.235 ENSMUST00000123476.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_-_113347273 4.158 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr3_-_127499095 4.130 ENSMUST00000182594.1
Ank2
ankyrin 2, brain
chr14_+_80000292 4.128 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr11_-_76577701 4.121 ENSMUST00000176179.1
Abr
active BCR-related gene
chr6_-_99028874 4.101 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr1_-_93101854 4.097 ENSMUST00000171796.1
ENSMUST00000171556.1
Kif1a

kinesin family member 1A

chr17_-_35838208 4.090 ENSMUST00000134978.2
Tubb5
tubulin, beta 5 class I
chr14_+_101840501 4.073 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr18_+_67088287 4.059 ENSMUST00000025402.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chrX_-_104857228 4.037 ENSMUST00000033575.5
Magee2
melanoma antigen, family E, 2
chr5_-_8367982 4.036 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr4_-_82705735 4.033 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr7_-_83884289 3.983 ENSMUST00000094216.3
Mesdc1
mesoderm development candidate 1
chrX_+_93675088 3.946 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr5_+_107331157 3.942 ENSMUST00000031215.8
ENSMUST00000112677.3
Brdt

bromodomain, testis-specific

chr13_-_84064772 3.889 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr5_+_30711849 3.880 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5

dihydropyrimidinase-like 5

chr1_+_135584773 3.865 ENSMUST00000067468.4
Gm4793
predicted gene 4793
chr4_+_13743424 3.863 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_96318014 3.855 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr14_-_124677089 3.829 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr3_+_117575227 3.792 ENSMUST00000106473.2
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr3_-_88458876 3.785 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr12_-_24252181 3.734 ENSMUST00000169148.1
Gm9312
predicted gene 9312
chr4_-_14621805 3.726 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr4_+_102421518 3.687 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr9_-_112187766 3.683 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr13_+_42709482 3.676 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr4_-_129121889 3.674 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr12_-_25096080 3.674 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr8_+_11312805 3.668 ENSMUST00000033899.7
Col4a2
collagen, type IV, alpha 2
chr8_+_70493156 3.664 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr8_+_95703037 3.660 ENSMUST00000073139.7
ENSMUST00000080666.7
Ndrg4

N-myc downstream regulated gene 4

chr5_-_110343009 3.658 ENSMUST00000058016.9
ENSMUST00000112478.3
P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr6_-_121003099 3.657 ENSMUST00000098457.2
ENSMUST00000150503.1
Mical3

microtubule associated monooxygenase, calponin and LIM domain containing 3

chr18_-_43438280 3.629 ENSMUST00000121805.1
Dpysl3
dihydropyrimidinase-like 3
chr9_-_15045378 3.619 ENSMUST00000164273.1
Panx1
pannexin 1
chr14_+_101840602 3.607 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr1_-_180483410 3.584 ENSMUST00000136521.1
ENSMUST00000179826.1
6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr3_-_88459047 3.575 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr11_+_79660532 3.573 ENSMUST00000155381.1
Rab11fip4
RAB11 family interacting protein 4 (class II)
chr17_+_55445375 3.570 ENSMUST00000133899.1
ENSMUST00000086878.3
St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr3_+_117575268 3.550 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr15_-_81697256 3.549 ENSMUST00000072910.5
Chadl
chondroadherin-like

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 12.8 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
3.6 32.6 GO:1900034 regulation of cellular response to heat(GO:1900034)
3.5 14.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
3.4 10.2 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
3.4 13.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
3.4 16.8 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
3.3 9.9 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
3.1 9.4 GO:0001543 ovarian follicle rupture(GO:0001543)
3.1 9.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
3.0 15.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
2.7 19.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
2.7 8.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
2.3 11.7 GO:2001025 positive regulation of response to drug(GO:2001025)
2.3 6.8 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374)
2.3 6.8 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
2.3 9.0 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
2.1 17.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
2.0 10.1 GO:0046684 response to pyrethroid(GO:0046684)
2.0 5.9 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
1.9 25.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
1.9 15.1 GO:0005513 detection of calcium ion(GO:0005513)
1.8 5.5 GO:0060912 cardiac cell fate specification(GO:0060912)
1.8 5.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
1.8 16.0 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
1.7 11.9 GO:0086018 SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
1.7 5.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.7 5.0 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.7 5.0 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
1.6 24.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.6 4.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
1.6 3.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
1.6 17.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
1.5 4.6 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.5 6.0 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
1.4 8.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.4 12.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
1.3 5.4 GO:0046898 response to cycloheximide(GO:0046898)
1.3 3.9 GO:0016598 protein arginylation(GO:0016598)
1.3 6.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.3 2.6 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
1.3 9.1 GO:0046103 inosine biosynthetic process(GO:0046103)
1.3 5.2 GO:0001922 B-1 B cell homeostasis(GO:0001922)
1.3 11.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
1.2 3.7 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.2 3.7 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
1.2 7.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
1.2 3.6 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703)
1.2 9.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
1.2 6.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
1.2 4.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.2 1.2 GO:0021940 regulation of cerebellar granule cell precursor proliferation(GO:0021936) cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
1.1 3.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.1 3.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
1.1 4.5 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
1.1 1.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.1 9.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.0 2.1 GO:0021586 pons maturation(GO:0021586)
1.0 18.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
1.0 4.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.0 7.8 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
1.0 2.9 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
1.0 2.9 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.0 3.8 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.0 3.8 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.9 2.8 GO:0070428 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.9 6.6 GO:0019532 oxalate transport(GO:0019532)
0.9 3.6 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.9 1.8 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.9 13.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.9 1.8 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.9 4.4 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.8 1.7 GO:0060025 regulation of synaptic activity(GO:0060025)
0.8 2.5 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.8 8.1 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.8 3.2 GO:2000830 vacuolar phosphate transport(GO:0007037) vitamin D3 metabolic process(GO:0070640) positive regulation of parathyroid hormone secretion(GO:2000830)
0.8 6.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.8 2.4 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.8 30.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.8 11.7 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.8 2.3 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.8 0.8 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.8 3.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.8 5.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.8 6.8 GO:0071420 cellular response to histamine(GO:0071420)
0.7 4.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.7 4.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.7 4.4 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.7 2.2 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.7 4.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.7 2.2 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.7 9.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.7 2.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.7 2.8 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.7 2.7 GO:0045054 constitutive secretory pathway(GO:0045054)
0.7 2.0 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.7 4.1 GO:0009405 pathogenesis(GO:0009405)
0.7 6.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.7 2.7 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.7 2.0 GO:0017085 response to insecticide(GO:0017085)
0.6 1.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.6 2.5 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.6 10.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.6 6.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.6 3.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.6 3.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.6 1.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.6 1.8 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.6 1.8 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.6 3.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.6 1.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.6 3.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.6 1.7 GO:0018377 N-terminal protein lipidation(GO:0006498) N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.6 3.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6 5.1 GO:0016198 axon choice point recognition(GO:0016198)
0.6 4.4 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.5 6.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.5 6.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.5 10.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.5 1.6 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.5 5.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.5 2.5 GO:0061073 anterior commissure morphogenesis(GO:0021960) ciliary body morphogenesis(GO:0061073)
0.5 3.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.5 2.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.5 1.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.5 3.4 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.5 1.4 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 4.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.5 1.9 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.5 2.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.5 3.7 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.5 3.7 GO:0014848 urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.5 1.4 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.4 18.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.4 1.3 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.4 15.4 GO:0050919 negative chemotaxis(GO:0050919)
0.4 1.2 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.2 GO:0061744 motor behavior(GO:0061744)
0.4 1.2 GO:1900365 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.4 1.2 GO:0009597 detection of virus(GO:0009597)
0.4 2.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.4 5.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.4 1.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.4 1.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382)
0.4 3.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.4 1.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.4 0.7 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.4 1.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.4 2.9 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.4 2.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.4 1.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.4 8.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.4 1.8 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.4 2.5 GO:0015808 L-alanine transport(GO:0015808)
0.4 3.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.4 3.9 GO:0007141 male meiosis I(GO:0007141)
0.4 7.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.3 5.6 GO:0048240 sperm capacitation(GO:0048240)
0.3 5.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.3 1.0 GO:0060017 parathyroid gland development(GO:0060017)
0.3 48.0 GO:0007416 synapse assembly(GO:0007416)
0.3 2.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 11.8 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 2.7 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.3 1.0 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.3 2.3 GO:0046549 retinal cone cell development(GO:0046549)
0.3 0.6 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.3 8.7 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.3 52.1 GO:0030041 actin filament polymerization(GO:0030041)
0.3 0.9 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.3 0.3 GO:2000646 negative regulation of PERK-mediated unfolded protein response(GO:1903898) positive regulation of receptor catabolic process(GO:2000646)
0.3 0.9 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 5.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 1.6 GO:0021626 hindbrain maturation(GO:0021578) cerebellum maturation(GO:0021590) central nervous system maturation(GO:0021626) cerebellar cortex maturation(GO:0021699)
0.3 1.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 0.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.3 8.0 GO:0016578 histone deubiquitination(GO:0016578)
0.3 3.8 GO:0030042 actin filament depolymerization(GO:0030042)
0.3 5.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.3 2.9 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.3 1.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 0.6 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.3 0.9 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.3 0.6 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.3 1.7 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.3 3.0 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.3 20.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.3 3.5 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.3 1.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.3 0.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 2.7 GO:0014010 Schwann cell proliferation(GO:0014010)
0.3 4.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 1.9 GO:0045760 positive regulation of action potential(GO:0045760)
0.3 1.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.3 1.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 2.5 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.3 3.0 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.2 2.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.2 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.2 0.7 GO:0090649 cellular response to manganese ion(GO:0071287) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 2.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 3.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 0.7 GO:0051036 regulation of endosome size(GO:0051036)
0.2 0.7 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 2.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 1.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 2.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 2.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 3.7 GO:0033198 response to ATP(GO:0033198)
0.2 1.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.2 3.5 GO:0008210 estrogen metabolic process(GO:0008210)
0.2 1.8 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.2 2.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 1.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.2 1.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 0.9 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.2 3.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2 3.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 2.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 1.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 1.8 GO:0015838 amino-acid betaine transport(GO:0015838)
0.2 4.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.2 0.5 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 0.5 GO:1902950 regulation of dendritic spine maintenance(GO:1902950) negative regulation of dendritic spine maintenance(GO:1902951)
0.2 1.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 1.0 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 4.6 GO:0019228 neuronal action potential(GO:0019228)
0.2 0.3 GO:0009838 abscission(GO:0009838)
0.2 0.9 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 1.8 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.2 0.7 GO:0048675 axon extension(GO:0048675)
0.2 6.2 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.2 0.2 GO:0002339 B cell selection(GO:0002339)
0.2 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.5 GO:0006868 glutamine transport(GO:0006868)
0.2 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.2 1.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 4.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 1.7 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.2 0.6 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 1.9 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.7 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.9 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 2.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 2.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.3 GO:0009212 dTTP biosynthetic process(GO:0006235) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 1.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.7 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) Golgi reassembly(GO:0090168)
0.1 0.9 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.9 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.1 1.0 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 2.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 2.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.4 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.1 0.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.2 GO:0032274 gonadotropin secretion(GO:0032274)
0.1 0.3 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 1.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.6 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.1 1.8 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.9 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 2.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 2.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.9 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.4 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164)
0.1 0.9 GO:0051503 calcium ion transmembrane import into mitochondrion(GO:0036444) adenine nucleotide transport(GO:0051503)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 1.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.3 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 1.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 8.7 GO:0000045 autophagosome assembly(GO:0000045)
0.1 0.3 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 1.1 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 6.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 3.1 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.1 0.7 GO:0001675 acrosome assembly(GO:0001675)
0.1 1.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 3.3 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.8 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 1.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.1 GO:0030516 regulation of axon extension(GO:0030516)
0.1 11.6 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 1.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 2.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 1.8 GO:0048167 regulation of synaptic plasticity(GO:0048167)
0.1 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 1.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 9.6 GO:0006906 vesicle fusion(GO:0006906)
0.1 1.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 1.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 1.5 GO:0043113 receptor clustering(GO:0043113)
0.1 1.2 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.7 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.2 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 1.0 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 1.5 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 4.9 GO:0051225 spindle assembly(GO:0051225)
0.1 2.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.1 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 3.8 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.1 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.4 GO:0015813 L-glutamate transport(GO:0015813)
0.1 12.5 GO:0006914 autophagy(GO:0006914)
0.1 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 2.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 2.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 1.1 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.1 1.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 0.3 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 1.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.0 GO:0006308 DNA catabolic process(GO:0006308)
0.1 1.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 5.3 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.5 GO:0048536 spleen development(GO:0048536)
0.0 2.7 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 1.6 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0072678 T cell migration(GO:0072678)
0.0 0.9 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.3 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 1.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 1.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.6 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.3 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
0.0 0.8 GO:0031333 negative regulation of protein complex assembly(GO:0031333)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0035633 negative regulation of heterotypic cell-cell adhesion(GO:0034115) maintenance of blood-brain barrier(GO:0035633) chemokine (C-C motif) ligand 2 secretion(GO:0035926) cell-cell adhesion involved in gastrulation(GO:0070586) regulation of cell-cell adhesion involved in gastrulation(GO:0070587) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 1.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.9 GO:0048477 oogenesis(GO:0048477)
0.0 0.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0006821 chloride transport(GO:0006821)
0.0 0.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0099536 synaptic signaling(GO:0099536)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.4 GO:0002142 stereocilia ankle link complex(GO:0002142)
3.9 39.0 GO:0045298 tubulin complex(GO:0045298)
3.0 27.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.7 1.7 GO:0033093 Weibel-Palade body(GO:0033093)
1.5 4.5 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
1.5 5.9 GO:0090537 CERF complex(GO:0090537)
1.5 36.3 GO:0071565 nBAF complex(GO:0071565)
1.4 5.7 GO:0044307 dendritic branch(GO:0044307)
1.4 5.6 GO:0099569 presynaptic cytoskeleton(GO:0099569)
1.4 6.8 GO:0044305 calyx of Held(GO:0044305)
1.3 20.4 GO:1990635 proximal dendrite(GO:1990635)
1.3 19.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.2 3.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.2 5.9 GO:0032437 cuticular plate(GO:0032437)
1.2 14.1 GO:0043083 synaptic cleft(GO:0043083)
1.2 4.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
1.1 9.1 GO:0001520 outer dense fiber(GO:0001520)
1.1 46.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
1.1 4.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
1.0 3.0 GO:0098855 HCN channel complex(GO:0098855)
0.9 15.6 GO:0032279 asymmetric synapse(GO:0032279)
0.8 4.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.8 3.3 GO:0031673 H zone(GO:0031673)
0.8 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.7 2.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 16.0 GO:0031430 M band(GO:0031430)
0.6 2.5 GO:0036449 microtubule minus-end(GO:0036449)
0.6 2.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.6 9.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.6 37.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.5 2.7 GO:1902710 GABA receptor complex(GO:1902710)
0.5 4.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5 1.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.5 1.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.5 5.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 7.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.5 4.8 GO:0032426 stereocilium tip(GO:0032426)
0.5 8.1 GO:0000124 SAGA complex(GO:0000124)
0.5 3.7 GO:0031012 extracellular matrix(GO:0031012)
0.4 1.3 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.4 6.9 GO:0031528 microvillus membrane(GO:0031528)
0.4 7.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.4 1.3 GO:0044308 axonal spine(GO:0044308)
0.4 3.7 GO:0044327 dendritic spine head(GO:0044327)
0.4 1.5 GO:0032444 activin responsive factor complex(GO:0032444)
0.4 20.0 GO:0031941 filamentous actin(GO:0031941)
0.4 3.0 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.4 2.6 GO:0000322 storage vacuole(GO:0000322)
0.4 1.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.4 2.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.4 7.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 1.8 GO:1990761 dendritic spine neck(GO:0044326) growth cone lamellipodium(GO:1990761)
0.4 2.5 GO:0005638 lamin filament(GO:0005638)
0.4 4.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.4 2.8 GO:1990909 Wnt signalosome(GO:1990909)
0.3 7.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 4.1 GO:0042581 specific granule(GO:0042581)
0.3 4.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 1.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 4.2 GO:0030057 desmosome(GO:0030057)
0.3 3.6 GO:0098845 postsynaptic endosome(GO:0098845)
0.3 7.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.3 5.4 GO:0034704 calcium channel complex(GO:0034704)
0.3 2.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 14.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 18.5 GO:0009925 basal plasma membrane(GO:0009925)
0.3 2.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 2.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 0.5 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.3 1.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 2.9 GO:0034464 BBSome(GO:0034464)
0.3 8.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3 22.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 5.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.3 2.0 GO:0060091 kinocilium(GO:0060091)
0.3 1.8 GO:0005916 fascia adherens(GO:0005916)
0.3 44.9 GO:0001726 ruffle(GO:0001726)
0.2 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 7.8 GO:0097440 apical dendrite(GO:0097440)
0.2 6.4 GO:0030425 dendrite(GO:0030425)
0.2 6.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 2.2 GO:0001739 sex chromatin(GO:0001739)
0.2 0.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 1.9 GO:0002177 manchette(GO:0002177)
0.2 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 21.5 GO:0030017 sarcomere(GO:0030017)
0.2 19.6 GO:0043204 perikaryon(GO:0043204)
0.2 5.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 2.6 GO:0032420 stereocilium(GO:0032420)
0.2 1.6 GO:0042382 paraspeckles(GO:0042382)
0.2 1.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 2.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 4.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.9 GO:0051233 spindle midzone(GO:0051233)
0.1 2.4 GO:0030139 endocytic vesicle(GO:0030139)
0.1 2.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.8 GO:0099512 supramolecular fiber(GO:0099512) polymeric cytoskeletal fiber(GO:0099513)
0.1 2.2 GO:0043679 axon terminus(GO:0043679)
0.1 26.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 3.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.6 GO:0031143 pseudopodium(GO:0031143)
0.1 1.4 GO:0000812 Swr1 complex(GO:0000812)
0.1 5.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 44.0 GO:0005874 microtubule(GO:0005874)
0.1 1.2 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.1 3.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 4.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 6.6 GO:0005581 collagen trimer(GO:0005581)
0.1 0.9 GO:0005871 kinesin complex(GO:0005871)
0.1 0.3 GO:0097443 sorting endosome(GO:0097443)
0.1 10.4 GO:0055037 recycling endosome(GO:0055037)
0.1 6.0 GO:0005776 autophagosome(GO:0005776)
0.1 2.8 GO:0030496 midbody(GO:0030496)
0.1 1.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 4.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.7 GO:0045180 basal cortex(GO:0045180)
0.1 6.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 14.2 GO:0000139 Golgi membrane(GO:0000139)
0.1 3.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.2 GO:0045177 apical part of cell(GO:0045177)
0.1 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 2.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 2.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.0 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 1.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0044432 endoplasmic reticulum part(GO:0044432)
0.0 0.7 GO:0044298 cell body membrane(GO:0044298)
0.0 1.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 2.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 8.4 GO:0097708 cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708)
0.0 1.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 2.3 GO:0005643 nuclear pore(GO:0005643)
0.0 1.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:0098797 plasma membrane protein complex(GO:0098797)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 5.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0042383 sarcolemma(GO:0042383)
0.0 1.8 GO:0030133 transport vesicle(GO:0030133)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 6.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 8.8 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 32.6 GO:0099609 microtubule lateral binding(GO:0099609)
4.4 17.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
4.3 12.8 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
3.6 28.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
3.3 16.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.0 5.9 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
1.8 25.6 GO:0031005 filamin binding(GO:0031005)
1.8 16.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.8 14.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.7 6.9 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.6 4.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
1.5 8.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.4 9.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.4 6.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.4 13.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.4 5.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.3 8.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.2 6.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.1 4.6 GO:0030348 syntaxin-3 binding(GO:0030348)
1.1 6.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
1.1 4.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.0 7.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.0 5.0 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.0 14.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
1.0 2.9 GO:0005119 smoothened binding(GO:0005119)
0.9 4.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.9 28.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.8 3.4 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.8 7.3 GO:0005523 tropomyosin binding(GO:0005523)
0.8 2.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.8 4.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.8 51.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.8 3.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.7 4.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.7 7.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.7 9.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.7 9.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.7 3.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.7 0.7 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.6 1.9 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.6 2.6 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.6 5.4 GO:0051434 BH3 domain binding(GO:0051434)
0.6 6.6 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.6 1.8 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.6 1.8 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.6 1.8 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.6 4.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.6 6.6 GO:0050897 cobalt ion binding(GO:0050897)
0.6 16.1 GO:0003785 actin monomer binding(GO:0003785)
0.5 2.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 4.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.5 1.6 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.5 2.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.5 1.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.5 5.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 10.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.5 1.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.5 8.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.5 4.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 8.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.5 3.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.5 1.4 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.4 3.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.4 2.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 2.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 1.3 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.4 1.8 GO:0070012 oligopeptidase activity(GO:0070012)
0.4 7.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.4 5.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.4 14.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 2.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.4 2.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 5.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 1.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.4 1.6 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.4 3.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.4 5.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.4 8.2 GO:0031489 myosin V binding(GO:0031489)
0.4 1.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.4 1.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.4 5.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 4.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.4 7.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 2.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 19.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 6.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 16.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 7.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3 1.0 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.3 5.1 GO:0003680 AT DNA binding(GO:0003680)
0.3 0.9 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.3 78.4 GO:0008017 microtubule binding(GO:0008017)
0.3 1.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.3 2.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 1.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.3 2.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 3.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.3 3.6 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.3 0.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 1.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.8 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3 4.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.3 22.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.3 9.9 GO:0017022 myosin binding(GO:0017022)
0.3 5.9 GO:0030506 ankyrin binding(GO:0030506)
0.3 2.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 10.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 1.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.3 0.8 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.3 6.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 2.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 6.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 0.7 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 5.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 3.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 2.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 0.7 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.2 5.8 GO:0042805 actinin binding(GO:0042805)
0.2 1.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 2.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 1.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 3.7 GO:0005521 lamin binding(GO:0005521)
0.2 5.7 GO:0070325 lipoprotein particle receptor binding(GO:0070325)
0.2 1.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 12.3 GO:0030276 clathrin binding(GO:0030276)
0.2 4.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.6 GO:0008527 taste receptor activity(GO:0008527)
0.2 0.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 2.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.2 GO:0048039 ubiquinone binding(GO:0048039)
0.2 9.3 GO:0015485 cholesterol binding(GO:0015485)
0.2 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.6 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.2 0.8 GO:0071532 ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 2.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 19.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 7.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 14.2 GO:0030674 protein binding, bridging(GO:0030674)
0.2 0.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 0.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 1.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 0.9 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 3.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 0.8 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 2.9 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 9.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 1.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 1.5 GO:0042287 MHC protein binding(GO:0042287)
0.2 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 1.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 11.2 GO:0044325 ion channel binding(GO:0044325)
0.1 0.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.1 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 12.9 GO:0008201 heparin binding(GO:0008201)
0.1 36.0 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 6.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 2.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.7 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 0.9 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 2.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 4.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 2.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808)
0.1 29.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 1.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 1.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 4.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 3.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 3.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 2.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 6.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.6 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 20.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 4.8 GO:0051117 ATPase binding(GO:0051117)
0.1 0.3 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 7.4 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 2.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 1.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.2 GO:0035240 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) dopamine binding(GO:0035240)
0.1 0.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 3.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 19.8 GO:0003779 actin binding(GO:0003779)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 1.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 3.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.3 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.0 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.1 0.2 GO:0043559 insulin binding(GO:0043559)
0.1 0.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 4.4 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.0 GO:0005496 steroid binding(GO:0005496)
0.1 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 10.7 GO:0016887 ATPase activity(GO:0016887)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 8.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.4 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 34.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.7 29.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.7 8.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.6 4.7 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.5 20.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.5 27.1 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.5 16.3 PID_IL3_PATHWAY IL3-mediated signaling events
0.5 20.6 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.5 21.0 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.4 26.7 PID_LKB1_PATHWAY LKB1 signaling events
0.3 8.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.3 12.3 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 4.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 11.0 PID_INSULIN_PATHWAY Insulin Pathway
0.2 2.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.2 7.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.2 5.0 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.2 4.9 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.2 15.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.2 4.4 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.2 3.4 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 8.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.2 8.3 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 4.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.2 3.7 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.2 1.2 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 0.9 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 1.7 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 8.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 2.6 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.1 1.7 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 7.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 1.8 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 2.1 PID_SHP2_PATHWAY SHP2 signaling
0.1 1.4 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 5.0 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.1 7.9 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 1.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 3.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.1 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 0.8 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 12.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 1.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.7 PID_BMP_PATHWAY BMP receptor signaling
0.1 1.3 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 7.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.5 PID_FOXO_PATHWAY FoxO family signaling
0.1 6.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.3 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.7 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.7 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.6 PID_P73PATHWAY p73 transcription factor network
0.0 0.3 PID_ARF_3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 27.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
1.0 23.4 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.0 6.8 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
1.0 15.2 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.9 9.0 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.9 22.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.8 4.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.8 29.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.8 0.8 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.7 6.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.7 11.5 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.7 13.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.6 9.0 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.6 16.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.6 10.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.6 13.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.5 7.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.5 6.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.4 15.0 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.4 8.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.4 15.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.4 14.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4 18.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.4 1.1 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.4 47.7 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.3 1.7 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 12.8 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.3 5.0 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.3 8.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.3 2.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 6.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.3 6.6 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.3 4.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 1.6 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 2.1 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 3.0 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.3 5.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 17.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 1.6 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.2 21.7 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.2 2.8 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 3.0 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 2.9 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 0.8 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.2 2.5 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 5.0 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 2.7 REACTOME_IL_3_5_AND_GM_CSF_SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.2 7.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 10.7 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 4.3 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 1.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.8 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 0.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.1 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 2.0 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 0.6 REACTOME_SIGNAL_AMPLIFICATION Genes involved in Signal amplification
0.1 12.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.6 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 4.4 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.2 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 9.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.8 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.1 2.4 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.8 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 0.6 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 1.1 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.2 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.2 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 0.9 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.6 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 3.4 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 3.8 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.1 2.4 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.3 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.9 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 1.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase