Motif ID: Sox5_Sry

Z-value: 1.624

Transcription factors associated with Sox5_Sry:

Gene SymbolEntrez IDGene Name
Sox5 ENSMUSG00000041540.10 Sox5
Sry ENSMUSG00000069036.3 Sry

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox5mm10_v2_chr6_-_143947092_1439471110.393.3e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Sox5_Sry

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_115824699 14.946 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr11_+_94044111 10.556 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr3_+_127633134 9.728 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr2_-_60125651 9.203 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr2_+_102658640 7.789 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr18_-_84086379 7.683 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr4_-_82505707 7.678 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr1_+_6730051 7.336 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr10_-_130280218 7.022 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr1_+_34005872 7.010 ENSMUST00000182296.1
Dst
dystonin
chr10_+_69706326 6.254 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr7_-_37770757 6.093 ENSMUST00000176680.1
Zfp536
zinc finger protein 536
chr6_+_15185456 5.835 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr2_+_124610573 5.777 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr1_+_6730135 5.468 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr1_-_119837613 5.382 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr4_-_82505274 5.329 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr12_-_99393010 5.268 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr9_-_72111172 5.216 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr5_+_17574268 5.193 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_+_109978004 5.133 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr18_-_62756275 4.947 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr2_+_154436437 4.732 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr11_+_94044194 4.701 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr11_-_50292302 4.648 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr13_-_56252163 4.594 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr16_-_16560046 4.542 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr4_-_110287479 4.540 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr12_-_34528844 4.431 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr4_-_82705735 4.392 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr6_-_113934679 4.063 ENSMUST00000101044.2
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr1_-_64121389 4.060 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr10_-_92165159 4.033 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr2_+_153031852 3.997 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr7_-_37773555 3.990 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr2_-_118549668 3.942 ENSMUST00000090219.6
Bmf
BCL2 modifying factor
chr19_-_4334001 3.899 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr4_-_82505749 3.852 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr4_-_97584612 3.756 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr8_+_120488416 3.748 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr11_+_94044241 3.748 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr1_-_138842429 3.746 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr6_+_120364094 3.729 ENSMUST00000100996.3
ENSMUST00000005108.7
Kdm5a

lysine (K)-specific demethylase 5A

chr17_-_70849644 3.700 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chrX_-_145505175 3.666 ENSMUST00000143610.1
Amot
angiomotin
chr15_-_10713537 3.628 ENSMUST00000090339.3
Rai14
retinoic acid induced 14
chr7_+_80186835 3.626 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr15_+_25773985 3.626 ENSMUST00000125667.1
Myo10
myosin X
chr6_-_71632651 3.591 ENSMUST00000167220.1
Kdm3a
lysine (K)-specific demethylase 3A
chr10_+_69534208 3.580 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr11_+_94044331 3.562 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr1_+_19103022 3.441 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr4_-_97584605 3.386 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr16_-_36784784 3.382 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr2_-_169405435 3.318 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr6_-_71632897 3.254 ENSMUST00000065509.4
Kdm3a
lysine (K)-specific demethylase 3A
chr9_-_72111651 3.162 ENSMUST00000185117.1
Tcf12
transcription factor 12
chr6_+_34709610 3.151 ENSMUST00000031775.6
Cald1
caldesmon 1
chr2_-_6722187 3.112 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr6_-_120364344 3.098 ENSMUST00000146667.1
Ccdc77
coiled-coil domain containing 77
chr6_+_15196949 3.093 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr10_+_69533803 3.057 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
Ank3


ankyrin 3, epithelial


chr15_+_25622525 3.051 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr1_+_55406163 2.997 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr13_-_97747399 2.972 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_119836999 2.934 ENSMUST00000163621.1
ENSMUST00000168303.1
Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr10_+_18407658 2.920 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr10_+_69534039 2.907 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chrX_-_143933089 2.883 ENSMUST00000087313.3
Dcx
doublecortin
chr16_+_42907563 2.872 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr2_-_84775388 2.865 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr9_+_70207342 2.843 ENSMUST00000034745.7
Myo1e
myosin IE
chr4_-_110290884 2.821 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_+_92185438 2.810 ENSMUST00000128781.2
Phf21a
PHD finger protein 21A
chr4_-_3938354 2.807 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr2_-_84775420 2.774 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chrX_-_23285532 2.773 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr16_-_4213404 2.730 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr11_+_44617310 2.719 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr4_+_144893077 2.707 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr6_+_128375456 2.667 ENSMUST00000100926.2
4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr1_-_165934900 2.665 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr2_+_181763315 2.619 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr1_-_14310198 2.611 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr18_+_69593361 2.584 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr6_-_144209558 2.576 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr11_-_115813621 2.552 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr6_+_34709442 2.535 ENSMUST00000115021.1
Cald1
caldesmon 1
chr1_-_119837338 2.527 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chrX_-_145505136 2.508 ENSMUST00000112835.1
Amot
angiomotin
chr16_-_78576649 2.475 ENSMUST00000114220.1
ENSMUST00000114219.1
ENSMUST00000114218.1
D16Ertd472e


DNA segment, Chr 16, ERATO Doi 472, expressed


chr6_-_93913678 2.461 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_87404916 2.452 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr9_+_96196246 2.443 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr10_+_17723220 2.428 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr4_+_144893127 2.392 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr12_-_31950535 2.375 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr13_+_44731281 2.367 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr4_-_45489794 2.364 ENSMUST00000146236.1
Shb
src homology 2 domain-containing transforming protein B
chr1_+_15287259 2.337 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr10_-_128704978 2.315 ENSMUST00000026416.7
ENSMUST00000026415.7
Cdk2

cyclin-dependent kinase 2

chr1_-_64121456 2.309 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr19_+_53310495 2.231 ENSMUST00000003870.7
Mxi1
Max interacting protein 1
chr19_-_56822161 2.218 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr4_+_97777606 2.211 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr13_-_97747373 2.162 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_-_91376490 2.151 ENSMUST00000107124.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr10_-_92164666 2.063 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr7_+_127876796 1.962 ENSMUST00000131000.1
Zfp646
zinc finger protein 646
chr4_-_91376433 1.936 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr9_-_50727921 1.911 ENSMUST00000118707.1
ENSMUST00000034566.8
Dixdc1

DIX domain containing 1

chr2_+_32535315 1.889 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chr2_+_92185467 1.869 ENSMUST00000111291.2
Phf21a
PHD finger protein 21A
chr3_-_116807733 1.834 ENSMUST00000159670.1
Agl
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chrX_-_12128350 1.826 ENSMUST00000123004.1
Bcor
BCL6 interacting corepressor
chr4_+_137993016 1.822 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
Eif4g3



eukaryotic translation initiation factor 4 gamma, 3



chr4_+_17853451 1.806 ENSMUST00000029881.3
Mmp16
matrix metallopeptidase 16
chr2_-_168601620 1.804 ENSMUST00000171689.1
ENSMUST00000137451.1
Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

chr3_+_131110350 1.800 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr1_-_97761538 1.789 ENSMUST00000171129.1
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr12_+_51348265 1.764 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr4_+_97777780 1.748 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr3_+_101377074 1.726 ENSMUST00000043983.5
Igsf3
immunoglobulin superfamily, member 3
chr9_+_118040576 1.723 ENSMUST00000134433.1
Azi2
5-azacytidine induced gene 2
chr9_-_50728067 1.720 ENSMUST00000117646.1
Dixdc1
DIX domain containing 1
chr12_+_51348370 1.714 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr1_-_12991109 1.710 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr12_+_40446050 1.687 ENSMUST00000037488.6
Dock4
dedicator of cytokinesis 4
chr2_-_181578906 1.683 ENSMUST00000136875.1
Uckl1
uridine-cytidine kinase 1-like 1
chr9_+_74976096 1.664 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr10_+_69925484 1.629 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chr10_+_69925800 1.627 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr1_+_81077274 1.617 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr16_-_16560201 1.615 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr2_-_6721890 1.600 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr18_+_69344503 1.591 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr11_-_58330319 1.587 ENSMUST00000065533.2
Gm9900
predicted gene 9900
chr4_-_24430838 1.582 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr17_-_51810866 1.550 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr1_+_160906372 1.534 ENSMUST00000161609.1
Rc3h1
RING CCCH (C3H) domains 1
chrX_-_12128386 1.512 ENSMUST00000145872.1
Bcor
BCL6 interacting corepressor
chr2_-_121171107 1.503 ENSMUST00000163766.1
ENSMUST00000146243.1
Zscan29

zinc finger SCAN domains 29

chr1_+_133045984 1.501 ENSMUST00000077730.5
Pik3c2b
phosphoinositide-3-kinase, class 2, beta polypeptide
chr17_+_4994904 1.498 ENSMUST00000092723.4
ENSMUST00000115797.2
Arid1b

AT rich interactive domain 1B (SWI-like)

chr7_+_75455534 1.494 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr1_+_158362330 1.481 ENSMUST00000170718.1
Astn1
astrotactin 1
chr1_+_66386968 1.477 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr3_-_95818941 1.461 ENSMUST00000090791.3
Rprd2
regulation of nuclear pre-mRNA domain containing 2
chr12_+_71136848 1.455 ENSMUST00000149564.1
ENSMUST00000045907.8
2700049A03Rik

RIKEN cDNA 2700049A03 gene

chr2_+_146221921 1.450 ENSMUST00000089257.4
Insm1
insulinoma-associated 1
chr10_+_69925766 1.438 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr9_+_118040509 1.420 ENSMUST00000133580.1
Azi2
5-azacytidine induced gene 2
chr12_-_83487708 1.420 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr13_+_44840686 1.408 ENSMUST00000173906.1
Jarid2
jumonji, AT rich interactive domain 2
chr4_-_44168252 1.386 ENSMUST00000145760.1
ENSMUST00000128426.1
Rnf38

ring finger protein 38

chr9_+_52047150 1.384 ENSMUST00000163153.1
Rdx
radixin
chr9_-_82975475 1.362 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr5_+_14514918 1.360 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr4_+_108460000 1.334 ENSMUST00000097925.2
Zcchc11
zinc finger, CCHC domain containing 11
chr4_+_32238950 1.333 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr18_-_43687695 1.328 ENSMUST00000082254.6
Jakmip2
janus kinase and microtubule interacting protein 2
chr3_+_55782500 1.325 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chrX_+_112615301 1.294 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr3_-_127225917 1.289 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr10_+_69925954 1.267 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr7_-_119895446 1.266 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr1_+_81077204 1.260 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr5_+_19907774 1.258 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr16_-_34263179 1.255 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr13_-_67360509 1.244 ENSMUST00000081582.6
ENSMUST00000185002.1
Zfp953
ZFP953
zinc finger protein 953
Protein Zfp953
chrX_-_143933204 1.242 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr4_+_108459389 1.235 ENSMUST00000106673.1
ENSMUST00000043368.5
Zcchc11

zinc finger, CCHC domain containing 11

chr5_-_131616599 1.218 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr7_+_27499315 1.214 ENSMUST00000098644.2
ENSMUST00000108355.1
Prx

periaxin

chr4_-_116405986 1.212 ENSMUST00000123072.1
ENSMUST00000144281.1
Mast2

microtubule associated serine/threonine kinase 2

chr19_+_40831296 1.211 ENSMUST00000119316.1
Ccnj
cyclin J
chr4_-_118409219 1.209 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr7_+_92819892 1.183 ENSMUST00000107180.1
ENSMUST00000107179.1
Rab30

RAB30, member RAS oncogene family

chr16_+_20097554 1.162 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr5_+_124862674 1.157 ENSMUST00000111417.2
Zfp664
zinc finger protein 664
chr3_-_127225847 1.145 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr6_-_114921778 1.145 ENSMUST00000032459.7
Vgll4
vestigial like 4 (Drosophila)
chr14_+_116925379 1.132 ENSMUST00000088483.3
Gpc6
glypican 6
chr9_+_122923050 1.112 ENSMUST00000051667.7
ENSMUST00000148851.1
Zfp105

zinc finger protein 105

chr16_-_34262945 1.094 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr4_-_52497244 1.089 ENSMUST00000114578.4
Vma21-ps
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae), pseudogene
chr6_+_86404336 1.081 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chrX_+_151803313 1.072 ENSMUST00000026292.8
Huwe1
HECT, UBA and WWE domain containing 1
chr11_+_58330712 1.069 ENSMUST00000116376.2
Sh3bp5l
SH3 binding domain protein 5 like
chr17_-_29888570 1.065 ENSMUST00000171691.1
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr19_-_29753600 1.063 ENSMUST00000175764.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr9_+_118040475 1.058 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chr12_-_98577940 1.056 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr2_+_18055203 1.047 ENSMUST00000028076.8
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr6_-_122340499 1.034 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr8_-_84237042 1.020 ENSMUST00000039480.5
Zswim4
zinc finger SWIM-type containing 4
chr6_+_65042575 0.989 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_-_63114516 0.984 ENSMUST00000097718.2
Ino80d
INO80 complex subunit D
chr9_-_75597643 0.957 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr18_+_34759551 0.945 ENSMUST00000097622.3
Fam53c
family with sequence similarity 53, member C

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 21.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
2.8 22.6 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
2.6 7.7 GO:0060023 soft palate development(GO:0060023)
2.3 6.8 GO:0007290 spermatid nucleus elongation(GO:0007290)
2.0 21.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.9 5.6 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.6 17.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
1.5 4.6 GO:0003162 atrioventricular node development(GO:0003162)
1.5 6.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.3 5.3 GO:0021603 cranial nerve formation(GO:0021603)
1.2 19.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.1 7.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.1 4.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.9 11.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.9 5.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.8 3.3 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.7 3.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.7 6.2 GO:0030035 microspike assembly(GO:0030035)
0.7 2.7 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.7 3.4 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.6 2.4 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.6 1.8 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.6 3.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.6 2.8 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.6 3.4 GO:0048840 otolith development(GO:0048840)
0.6 3.9 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.5 3.7 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.5 1.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.5 1.5 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.5 5.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.5 1.5 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.5 6.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.5 2.3 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.5 1.4 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.4 3.9 GO:0048102 autophagic cell death(GO:0048102)
0.4 2.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 4.7 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.4 1.7 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.4 5.9 GO:0060013 righting reflex(GO:0060013)
0.4 4.2 GO:0042118 endothelial cell activation(GO:0042118)
0.4 3.2 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.4 0.8 GO:0061198 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) fungiform papilla formation(GO:0061198)
0.4 1.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.4 0.8 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.4 0.7 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3 3.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 1.7 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.3 4.0 GO:0072189 ureter development(GO:0072189)
0.3 2.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.3 0.6 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.3 7.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 2.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.3 6.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.3 2.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.3 2.9 GO:0097475 motor neuron migration(GO:0097475)
0.3 1.7 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 1.4 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.3 4.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 2.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 2.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 2.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 2.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 0.8 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.3 4.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 0.8 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 1.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 1.5 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2 1.7 GO:0032808 lacrimal gland development(GO:0032808)
0.2 1.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 0.7 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.2 2.6 GO:0060539 diaphragm development(GO:0060539)
0.2 2.6 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.2 1.8 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.6 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.2 1.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 0.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 0.9 GO:0046684 response to pyrethroid(GO:0046684)
0.2 1.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 0.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 1.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 0.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.2 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.6 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2 1.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 1.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 1.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.7 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.6 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.8 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 5.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.4 GO:0048686 regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 1.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.6 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 5.4 GO:0021591 ventricular system development(GO:0021591)
0.1 0.5 GO:0007144 female meiosis I(GO:0007144)
0.1 0.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 1.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.8 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 9.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.4 GO:0044849 estrous cycle(GO:0044849)
0.1 0.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.5 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 2.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:0060613 fat pad development(GO:0060613)
0.1 1.8 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.6 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.1 3.6 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 3.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 2.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 4.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.3 GO:0010225 response to UV-C(GO:0010225)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.7 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 3.1 GO:0016574 histone ubiquitination(GO:0016574)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.5 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 0.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 1.3 GO:0001967 suckling behavior(GO:0001967)
0.1 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.1 GO:0060397 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.8 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 1.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.5 GO:0030901 midbrain development(GO:0030901)
0.0 0.3 GO:0009301 snRNA transcription(GO:0009301)
0.0 1.1 GO:0035329 hippo signaling(GO:0035329)
0.0 1.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.0 0.5 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 4.1 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0060160 gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883) negative regulation of dopamine receptor signaling pathway(GO:0060160) regulation of locomotion involved in locomotory behavior(GO:0090325)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 2.6 GO:0000910 cytokinesis(GO:0000910)
0.0 3.7 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.9 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.9 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.9 GO:0051591 response to cAMP(GO:0051591)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 4.2 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 1.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.4 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.0 GO:0031673 H zone(GO:0031673)
1.1 21.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.0 21.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.9 4.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.8 2.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.6 5.7 GO:0030478 actin cap(GO:0030478)
0.6 2.8 GO:0032437 cuticular plate(GO:0032437)
0.5 7.4 GO:0042788 polysomal ribosome(GO:0042788)
0.5 3.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3 1.4 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.3 2.6 GO:0097165 nuclear stress granule(GO:0097165)
0.2 7.8 GO:0030673 axolemma(GO:0030673)
0.2 1.2 GO:1990130 Iml1 complex(GO:1990130)
0.2 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 2.0 GO:0071565 nBAF complex(GO:0071565)
0.2 2.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 2.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 2.0 GO:0001739 sex chromatin(GO:0001739)
0.2 0.6 GO:0034657 GID complex(GO:0034657)
0.2 0.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 11.3 GO:0016459 myosin complex(GO:0016459)
0.2 1.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.2 1.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 2.5 GO:1990635 proximal dendrite(GO:1990635)
0.2 4.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 6.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.4 GO:0031430 M band(GO:0031430)
0.1 5.2 GO:1990391 DNA repair complex(GO:1990391)
0.1 2.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 14.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 17.4 GO:0032993 protein-DNA complex(GO:0032993)
0.1 3.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 1.2 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 4.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.0 GO:0043596 nuclear replication fork(GO:0043596)
0.1 7.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.7 GO:0031011 Ino80 complex(GO:0031011)
0.1 2.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 4.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.7 GO:0072562 blood microparticle(GO:0072562)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.7 GO:0042581 specific granule(GO:0042581)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.0 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 1.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 6.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 20.8 GO:0005815 microtubule organizing center(GO:0005815)
0.0 3.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 4.1 GO:0030027 lamellipodium(GO:0030027)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 5.2 GO:0000785 chromatin(GO:0000785)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 2.7 GO:0043679 axon terminus(GO:0043679)
0.0 1.3 GO:0030426 growth cone(GO:0030426)
0.0 2.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.7 GO:0030018 Z disc(GO:0030018)
0.0 2.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 10.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.4 24.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.3 7.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.2 6.2 GO:0043532 angiostatin binding(GO:0043532)
1.1 3.4 GO:0042936 dipeptide transporter activity(GO:0042936)
1.0 4.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.9 3.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.7 4.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.7 25.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.7 2.7 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.7 10.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.6 3.9 GO:0045322 unmethylated CpG binding(GO:0045322)
0.6 11.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 2.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.5 30.9 GO:0030507 spectrin binding(GO:0030507)
0.5 2.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.4 1.8 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.4 8.4 GO:0035497 cAMP response element binding(GO:0035497)
0.4 6.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 1.7 GO:0004849 uridine kinase activity(GO:0004849)
0.3 5.6 GO:0001848 complement binding(GO:0001848)
0.3 9.9 GO:0017091 AU-rich element binding(GO:0017091)
0.3 1.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.3 4.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 4.0 GO:0008432 JUN kinase binding(GO:0008432)
0.2 9.3 GO:0070888 E-box binding(GO:0070888)
0.2 3.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 2.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 4.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 31.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 0.7 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.9 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 4.6 GO:0042605 peptide antigen binding(GO:0042605)
0.2 3.1 GO:0032452 histone demethylase activity(GO:0032452)
0.2 2.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 0.8 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 1.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 2.3 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.5 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 3.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.6 GO:0002135 CTP binding(GO:0002135)
0.1 1.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.5 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 5.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.5 GO:0035198 miRNA binding(GO:0035198)
0.1 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 8.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 12.1 GO:0001047 core promoter binding(GO:0001047)
0.1 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 11.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.9 GO:0031402 sodium ion binding(GO:0031402)
0.0 3.5 GO:0003774 motor activity(GO:0003774)
0.0 2.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 12.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 9.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 29.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.3 21.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.2 3.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.2 2.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 14.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 7.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 13.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.7 PID_FOXO_PATHWAY FoxO family signaling
0.1 4.1 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 3.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 6.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 2.2 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 4.4 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 2.4 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 2.6 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.4 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 2.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 2.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 21.3 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.6 21.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 8.0 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 12.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.3 4.1 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 3.0 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 7.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 5.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2 11.7 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 2.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 4.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 10.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 4.0 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 5.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 0.6 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.7 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.9 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.7 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 6.0 REACTOME_MEIOSIS Genes involved in Meiosis
0.1 1.1 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 1.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.4 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.7 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.9 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.4 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 2.5 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation