Z-value: 1.089
Transcription factors associated with Srf:
Activity-expression correlation:
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Showing 1 to 20 of 126 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihood Term Description
4.1
12.2
GO:0072223
metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
1.4
8.5
GO:0021797
forebrain anterior/posterior pattern specification(GO:0021797)
1.9
7.6
GO:0030091
protein repair(GO:0030091)
0.1
5.4
GO:0010718
positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1
4.4
GO:0071277
cellular response to calcium ion(GO:0071277)
0.3
4.0
GO:1903504
regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.3
3.4
GO:1902166
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.2
3.3
GO:0035994
response to muscle stretch(GO:0035994)
0.6
3.1
GO:0048133
germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3
2.9
GO:0042095
interferon-gamma biosynthetic process(GO:0042095)
0.0
2.9
GO:0070527
platelet aggregation(GO:0070527)
0.1
2.7
GO:0001706
endoderm formation(GO:0001706)
0.4
2.5
GO:0072257
metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.8
2.4
GO:0010814
substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.6
2.3
GO:0060025
regulation of synaptic activity(GO:0060025)
0.0
2.3
GO:0006457
protein folding(GO:0006457)
0.1
2.0
GO:0050765
negative regulation of phagocytosis(GO:0050765)
0.2
1.7
GO:0090043
regulation of tubulin deacetylation(GO:0090043)
0.1
1.7
GO:0050965
detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.2
1.6
GO:0048739
cardiac muscle fiber development(GO:0048739)
Gene overrepresentation in cellular_component category:
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Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihood Term Description
0.0
5.5
GO:0000139
Golgi membrane(GO:0000139)
0.2
4.0
GO:0005680
anaphase-promoting complex(GO:0005680)
0.5
3.3
GO:0035976
AP1 complex(GO:0035976)
0.5
3.1
GO:0016602
CCAAT-binding factor complex(GO:0016602)
0.5
2.4
GO:0033093
Weibel-Palade body(GO:0033093)
0.1
1.7
GO:0000124
SAGA complex(GO:0000124)
0.4
1.5
GO:1902937
inward rectifier potassium channel complex(GO:1902937)
0.0
1.5
GO:0043034
costamere(GO:0043034)
0.1
1.4
GO:0000276
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1
1.4
GO:0016460
myosin II complex(GO:0016460)
0.0
1.2
GO:0030018
Z disc(GO:0030018)
0.0
1.2
GO:0005902
microvillus(GO:0005902)
0.2
1.1
GO:0097226
sperm mitochondrial sheath(GO:0097226)
0.1
1.0
GO:0005885
Arp2/3 protein complex(GO:0005885)
0.0
1.0
GO:0000794
condensed nuclear chromosome(GO:0000794)
0.0
0.8
GO:0030285
integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0
0.7
GO:0070938
contractile ring(GO:0070938)
0.1
0.5
GO:0005853
eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0
0.4
GO:0005862
muscle thin filament tropomyosin(GO:0005862)
0.0
0.3
GO:0031229
integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihood Term Description
3.0
12.2
GO:0044729
hemi-methylated DNA-binding(GO:0044729)
1.3
7.6
GO:0033743
peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0
6.8
GO:0001078
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0
6.0
GO:0000978
RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0
3.4
GO:0002039
p53 binding(GO:0002039)
0.1
3.3
GO:0070412
R-SMAD binding(GO:0070412)
0.0
3.1
GO:0035064
methylated histone binding(GO:0035064)
0.2
2.7
GO:0017017
MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0
2.5
GO:0005200
structural constituent of cytoskeleton(GO:0005200)
0.0
2.4
GO:0004222
metalloendopeptidase activity(GO:0004222)
0.1
2.0
GO:0008307
structural constituent of muscle(GO:0008307)
0.2
1.7
GO:0032036
myosin heavy chain binding(GO:0032036)
0.0
1.7
GO:0016922
ligand-dependent nuclear receptor binding(GO:0016922)
0.0
1.7
GO:0004879
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.2
1.6
GO:0000774
adenyl-nucleotide exchange factor activity(GO:0000774)
0.3
1.5
GO:1902282
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1
1.5
GO:0071837
HMG box domain binding(GO:0071837)
0.1
1.2
GO:0022841
potassium ion leak channel activity(GO:0022841)
0.1
1.2
GO:0048407
platelet-derived growth factor binding(GO:0048407)
0.2
1.1
GO:0002135
CTP binding(GO:0002135) sulfonylurea receptor binding(GO:0017098)
Gene overrepresentation in C2:CP category:
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Showing 1 to 14 of 14 entries
Gene overrepresentation in C2:CP:REACTOME category:
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Showing 1 to 13 of 13 entries