Motif ID: Tbp
Z-value: 2.507
Transcription factors associated with Tbp:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Tbp | ENSMUSG00000014767.10 | Tbp |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tbp | mm10_v2_chr17_+_15499888_15499960 | -0.52 | 4.4e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.8 | 29.1 | GO:0015671 | oxygen transport(GO:0015671) |
| 4.6 | 13.7 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 4.4 | 21.8 | GO:0060591 | chondroblast differentiation(GO:0060591) |
| 4.3 | 21.5 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 3.9 | 121.2 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 3.9 | 15.6 | GO:0045091 | regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) |
| 3.3 | 13.4 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
| 3.3 | 10.0 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
| 3.3 | 9.9 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 3.1 | 15.7 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 3.1 | 15.5 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 2.8 | 11.3 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 2.7 | 10.9 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 2.4 | 31.5 | GO:0042573 | retinoic acid metabolic process(GO:0042573) |
| 2.3 | 9.2 | GO:0002484 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485) |
| 2.3 | 13.5 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 2.2 | 6.6 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
| 2.1 | 6.3 | GO:1901355 | response to rapamycin(GO:1901355) |
| 2.0 | 5.9 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407) |
| 2.0 | 7.9 | GO:0033087 | negative regulation of immature T cell proliferation(GO:0033087) |
| 1.9 | 13.1 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
| 1.8 | 10.8 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 1.7 | 12.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 1.7 | 10.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 1.7 | 10.0 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 1.7 | 31.5 | GO:0019430 | removal of superoxide radicals(GO:0019430) |
| 1.6 | 6.6 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 1.6 | 11.5 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 1.6 | 16.2 | GO:0042095 | interferon-gamma biosynthetic process(GO:0042095) |
| 1.6 | 9.6 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 1.6 | 19.0 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 1.5 | 4.6 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
| 1.4 | 7.1 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 1.4 | 4.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 1.4 | 4.1 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
| 1.2 | 3.7 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
| 1.1 | 4.6 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 1.1 | 20.5 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 1.1 | 2.2 | GO:0060558 | regulation of calcidiol 1-monooxygenase activity(GO:0060558) |
| 1.1 | 3.2 | GO:0043031 | regulation of phosphatidylcholine catabolic process(GO:0010899) negative regulation of macrophage activation(GO:0043031) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) regulation of microglial cell activation(GO:1903978) |
| 1.1 | 6.4 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
| 1.0 | 13.8 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 1.0 | 5.8 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 1.0 | 5.7 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.9 | 2.7 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.9 | 9.8 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.8 | 18.7 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.8 | 9.8 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.8 | 2.4 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) positive regulation of calcium-transporting ATPase activity(GO:1901896) |
| 0.8 | 0.8 | GO:1903935 | response to sodium arsenite(GO:1903935) |
| 0.7 | 2.2 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.7 | 4.8 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 0.7 | 2.0 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
| 0.6 | 11.4 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.6 | 46.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.6 | 11.4 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.6 | 3.6 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.6 | 1.8 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.6 | 1.2 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.6 | 9.0 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.6 | 1.7 | GO:0042713 | sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455) |
| 0.5 | 4.3 | GO:1901970 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
| 0.5 | 1.6 | GO:1902022 | ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) brain renin-angiotensin system(GO:0002035) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of activation of Janus kinase activity(GO:0010533) L-lysine transport(GO:1902022) |
| 0.5 | 3.6 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.5 | 1.8 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.4 | 3.8 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.4 | 6.5 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.4 | 6.5 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.4 | 6.7 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.4 | 10.6 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.4 | 6.5 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.4 | 2.2 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
| 0.3 | 1.0 | GO:1903225 | regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.3 | 2.4 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.3 | 3.2 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.3 | 0.6 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
| 0.3 | 2.5 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
| 0.3 | 2.2 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.3 | 2.2 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 0.3 | 0.9 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
| 0.3 | 6.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.3 | 0.9 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
| 0.3 | 0.6 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.3 | 28.3 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.3 | 2.1 | GO:0000050 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
| 0.3 | 3.1 | GO:0051984 | positive regulation of chromosome segregation(GO:0051984) |
| 0.3 | 0.8 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.2 | 1.1 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.2 | 3.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.2 | 7.5 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.2 | 3.7 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) |
| 0.2 | 15.3 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.2 | 0.6 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.2 | 0.7 | GO:1904995 | negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
| 0.2 | 7.9 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.2 | 2.2 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.2 | 2.9 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.2 | 1.0 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.1 | 0.6 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.1 | 2.2 | GO:0071276 | cellular response to cadmium ion(GO:0071276) |
| 0.1 | 5.8 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.1 | 9.2 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) |
| 0.1 | 3.5 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.1 | 4.7 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.1 | 2.0 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.1 | 0.9 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.1 | 1.6 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
| 0.1 | 7.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 2.8 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 1.0 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 2.2 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.1 | 1.9 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.1 | 0.2 | GO:0021972 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
| 0.1 | 3.1 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 2.6 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.1 | 0.1 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501) |
| 0.1 | 1.7 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 3.1 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.1 | 0.4 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.0 | 2.6 | GO:0051480 | regulation of cytosolic calcium ion concentration(GO:0051480) |
| 0.0 | 1.3 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 0.0 | 2.6 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 2.5 | GO:0061515 | myeloid cell development(GO:0061515) |
| 0.0 | 0.6 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.0 | 0.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.0 | 4.0 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 1.9 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
| 0.0 | 1.1 | GO:1902593 | protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593) |
| 0.0 | 0.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.0 | 1.9 | GO:0008584 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.0 | 1.0 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 2.9 | GO:0048754 | branching morphogenesis of an epithelial tube(GO:0048754) |
| 0.0 | 1.5 | GO:0031397 | negative regulation of protein ubiquitination(GO:0031397) |
| 0.0 | 0.5 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 3.1 | GO:0042254 | ribosome biogenesis(GO:0042254) |
| 0.0 | 0.7 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 0.0 | GO:2000510 | positive regulation of dendritic cell chemotaxis(GO:2000510) |
| 0.0 | 0.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 2.0 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
| 0.0 | 1.0 | GO:0043010 | camera-type eye development(GO:0043010) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 13.4 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 3.9 | 15.7 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 3.7 | 120.6 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 1.9 | 13.2 | GO:0097452 | GAIT complex(GO:0097452) |
| 1.6 | 9.6 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 1.3 | 50.7 | GO:0000786 | nucleosome(GO:0000786) |
| 1.3 | 6.5 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 1.2 | 4.8 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 1.2 | 7.1 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 1.1 | 6.4 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 1.0 | 4.1 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
| 1.0 | 7.9 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.9 | 4.7 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
| 0.9 | 4.6 | GO:1990357 | terminal web(GO:1990357) |
| 0.9 | 3.6 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.8 | 5.0 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.8 | 2.4 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.8 | 9.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.8 | 3.1 | GO:0032021 | NELF complex(GO:0032021) |
| 0.8 | 3.8 | GO:0001652 | granular component(GO:0001652) |
| 0.7 | 18.6 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.7 | 2.1 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
| 0.6 | 3.2 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.6 | 14.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.6 | 29.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.5 | 10.0 | GO:0010369 | chromocenter(GO:0010369) |
| 0.4 | 2.2 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.4 | 3.7 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.3 | 2.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.3 | 20.5 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.3 | 1.9 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.3 | 2.2 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.3 | 15.1 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.3 | 3.2 | GO:0045120 | pronucleus(GO:0045120) |
| 0.3 | 0.8 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.3 | 1.6 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.2 | 3.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.2 | 3.3 | GO:0044754 | autolysosome(GO:0044754) |
| 0.2 | 14.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.2 | 2.8 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 24.0 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.2 | 3.0 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 7.0 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.2 | 6.5 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 1.0 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418) |
| 0.1 | 1.8 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 2.4 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.1 | 6.0 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 0.9 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.1 | 0.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 1.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 0.4 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.1 | 6.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 3.7 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 1.0 | GO:0031091 | platelet alpha granule(GO:0031091) |
| 0.1 | 1.0 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 22.7 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 6.6 | GO:0000776 | kinetochore(GO:0000776) |
| 0.1 | 14.8 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.1 | 2.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 19.2 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.1 | 0.1 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 0.0 | 2.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 4.0 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 1.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 7.9 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 17.8 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 9.4 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 1.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 3.7 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.6 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 0.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 1.9 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.4 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 53.0 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.0 | 90.1 | GO:0005634 | nucleus(GO:0005634) |
| 0.0 | 1.0 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.0 | 2.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.6 | GO:0045177 | apical part of cell(GO:0045177) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.8 | 29.1 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 5.3 | 31.5 | GO:0019841 | retinol binding(GO:0019841) |
| 4.4 | 13.2 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 3.9 | 15.7 | GO:1990254 | keratin filament binding(GO:1990254) |
| 3.9 | 15.6 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 3.3 | 9.9 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 2.8 | 28.5 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 2.7 | 13.4 | GO:0035240 | dopamine binding(GO:0035240) |
| 2.6 | 10.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 2.0 | 16.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 1.9 | 93.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 1.5 | 10.8 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 1.4 | 18.7 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 1.4 | 7.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 1.4 | 9.6 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 1.2 | 1.2 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 1.1 | 4.6 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 1.1 | 4.2 | GO:0019808 | polyamine binding(GO:0019808) |
| 1.0 | 4.8 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.9 | 3.8 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.9 | 8.4 | GO:0032564 | dATP binding(GO:0032564) |
| 0.9 | 3.7 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.9 | 2.7 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.8 | 1.6 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.8 | 3.0 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.7 | 3.6 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.7 | 9.2 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.7 | 9.9 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.7 | 5.9 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.7 | 14.4 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.6 | 3.2 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.5 | 11.5 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.5 | 5.0 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.5 | 15.8 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.5 | 21.5 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.4 | 2.2 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.4 | 2.6 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.4 | 2.9 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.4 | 6.9 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.4 | 2.8 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.4 | 4.3 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.3 | 9.8 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.3 | 1.4 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.3 | 4.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.3 | 3.2 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.3 | 0.9 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.3 | 0.9 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
| 0.3 | 6.5 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.3 | 3.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.3 | 60.5 | GO:0042393 | histone binding(GO:0042393) |
| 0.3 | 11.3 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.2 | 20.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 10.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.2 | 6.0 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 1.0 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.2 | 0.6 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.2 | 3.1 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.2 | 6.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.2 | 1.1 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.2 | 0.6 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.2 | 0.9 | GO:0016151 | nickel cation binding(GO:0016151) |
| 0.2 | 7.2 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.2 | 1.0 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 2.5 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 26.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 2.4 | GO:0051861 | glycolipid binding(GO:0051861) |
| 0.1 | 1.2 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 3.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 2.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.8 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 1.6 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 3.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.5 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
| 0.1 | 2.2 | GO:0042805 | actinin binding(GO:0042805) |
| 0.1 | 3.4 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 1.9 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 2.2 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 1.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 1.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 1.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 6.3 | GO:0002020 | protease binding(GO:0002020) |
| 0.1 | 2.2 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.1 | 7.1 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.1 | 16.4 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.1 | 104.8 | GO:0003677 | DNA binding(GO:0003677) |
| 0.1 | 1.6 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.2 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 8.3 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 2.4 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
| 0.0 | 0.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 0.1 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.0 | 2.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.1 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.0 | 0.8 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.0 | 0.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 2.4 | GO:0005506 | iron ion binding(GO:0005506) |
| 0.0 | 0.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 1.0 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 5.5 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 6.5 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.9 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 2.1 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 21.5 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.9 | 42.1 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.6 | 19.8 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.5 | 18.7 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.5 | 9.9 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.4 | 20.8 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.4 | 15.6 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.4 | 11.5 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.3 | 10.1 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
| 0.3 | 28.0 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.2 | 8.1 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.2 | 3.7 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 4.6 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.2 | 6.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.2 | 3.9 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.2 | 4.4 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 13.2 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 3.1 | PID_ATM_PATHWAY | ATM pathway |
| 0.1 | 5.7 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 6.5 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.1 | 9.0 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.1 | 3.0 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 2.1 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 1.0 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.0 | 1.0 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 1.8 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.2 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.2 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.0 | 0.4 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 0.3 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 0.5 | PID_P53_REGULATION_PATHWAY | p53 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.1 | 160.4 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 2.6 | 7.9 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 2.1 | 33.0 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 2.0 | 9.9 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 1.2 | 13.4 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 1.2 | 10.8 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.9 | 22.8 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.8 | 4.6 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.8 | 20.5 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.6 | 15.9 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.5 | 29.6 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.5 | 6.6 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.5 | 4.1 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.4 | 7.0 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.4 | 4.7 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.4 | 2.9 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.4 | 12.6 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.3 | 3.7 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.3 | 13.3 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.3 | 3.2 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.3 | 4.2 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.3 | 4.3 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | Genes involved in Phosphorylation of the APC/C |
| 0.2 | 13.7 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.2 | 12.7 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.2 | 5.6 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.2 | 5.0 | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.1 | 1.2 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 1.1 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 2.2 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 2.0 | REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.1 | 9.6 | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.1 | 8.5 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 2.2 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.1 | 1.0 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 12.3 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 6.0 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 2.7 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 1.8 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 2.4 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 1.6 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 10.0 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 3.2 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 1.4 | REACTOME_IRON_UPTAKE_AND_TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 0.8 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.0 | 1.8 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.4 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.4 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.2 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.0 | 0.7 | REACTOME_TRANSLATION | Genes involved in Translation |
