Motif ID: Tbr1

Z-value: 0.922


Transcription factors associated with Tbr1:

Gene SymbolEntrez IDGene Name
Tbr1 ENSMUSG00000035033.9 Tbr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbr1mm10_v2_chr2_+_61804453_61804538-0.341.2e-02Click!


Activity profile for motif Tbr1.

activity profile for motif Tbr1


Sorted Z-values histogram for motif Tbr1

Sorted Z-values for motif Tbr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_120899067 7.676 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr10_+_57784859 5.441 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr2_+_71528657 5.213 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr2_+_164562579 3.676 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr2_-_71546745 3.651 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr2_+_71529085 3.627 ENSMUST00000152711.1
Dlx1
distal-less homeobox 1
chr5_+_111733924 3.539 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr9_-_21760275 3.459 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr10_+_57784914 3.455 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr3_-_115715031 3.361 ENSMUST00000055676.2
S1pr1
sphingosine-1-phosphate receptor 1
chr9_-_43239816 3.339 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr4_-_109665249 3.284 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chrX_+_100625737 3.098 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr1_-_138847579 3.042 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr11_-_32222233 2.783 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr1_-_189688074 2.766 ENSMUST00000171929.1
ENSMUST00000165962.1
Cenpf

centromere protein F

chr3_-_145649970 2.731 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr17_+_87635974 2.656 ENSMUST00000053577.8
Epcam
epithelial cell adhesion molecule
chr14_+_62292475 2.618 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr3_+_135212557 2.543 ENSMUST00000062893.7
Cenpe
centromere protein E
chr1_-_186705980 2.542 ENSMUST00000045288.8
Tgfb2
transforming growth factor, beta 2
chr7_-_116237767 2.444 ENSMUST00000182834.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr3_+_94693556 2.442 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr3_-_157925056 2.416 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr2_-_91931675 2.402 ENSMUST00000111309.1
Mdk
midkine
chr18_+_84088077 2.392 ENSMUST00000060223.2
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr1_-_138848576 2.391 ENSMUST00000112030.2
Lhx9
LIM homeobox protein 9
chr7_-_46672537 2.376 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr4_+_94614483 2.371 ENSMUST00000030311.4
ENSMUST00000107104.2
Ift74

intraflagellar transport 74

chr9_-_106199253 2.348 ENSMUST00000140761.1
Ppm1m
protein phosphatase 1M
chr10_+_26229707 2.335 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr9_-_72491939 2.300 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr2_-_91931774 2.283 ENSMUST00000069423.6
Mdk
midkine
chr9_+_22454290 2.270 ENSMUST00000168332.1
Gm17545
predicted gene, 17545
chr12_+_85473883 2.268 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr4_+_59626189 2.267 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr2_-_91931696 2.264 ENSMUST00000090602.5
Mdk
midkine
chr11_-_84068766 2.233 ENSMUST00000018792.5
Dusp14
dual specificity phosphatase 14
chr11_-_69900949 2.230 ENSMUST00000102580.3
2810408A11Rik
RIKEN cDNA 2810408A11 gene
chr3_-_95904683 2.205 ENSMUST00000147962.1
ENSMUST00000036181.8
Car14

carbonic anhydrase 14

chr14_-_70642268 2.190 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr14_-_8309770 2.180 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chr10_+_20347788 2.135 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr14_+_60732906 2.129 ENSMUST00000162945.1
Spata13
spermatogenesis associated 13
chr5_-_34169409 2.094 ENSMUST00000042954.7
ENSMUST00000060049.6
Poln
Haus3
DNA polymerase N
HAUS augmin-like complex, subunit 3
chrX_-_8145713 2.086 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
Rbm3


RNA binding motif protein 3


chr8_+_45885479 2.082 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr9_+_3025417 2.080 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr7_-_130573118 2.078 ENSMUST00000159694.1
Nsmce4a
non-SMC element 4 homolog A (S. cerevisiae)
chr13_-_47105790 2.063 ENSMUST00000129352.1
Dek
DEK oncogene (DNA binding)
chr11_-_69900930 2.054 ENSMUST00000018714.6
ENSMUST00000128046.1
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr15_+_83526854 2.004 ENSMUST00000016902.3
Bik
BCL2-interacting killer
chr15_+_79891631 1.967 ENSMUST00000177350.1
ENSMUST00000177483.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr10_+_62947011 1.960 ENSMUST00000131422.1
Dna2
DNA replication helicase 2 homolog (yeast)
chr8_+_57511833 1.944 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr3_-_89393294 1.910 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr13_-_116309639 1.908 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr6_+_134929118 1.908 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr14_-_19418930 1.901 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr17_+_29093763 1.887 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr18_+_5591860 1.885 ENSMUST00000025081.5
ENSMUST00000159390.1
Zeb1

zinc finger E-box binding homeobox 1

chr6_+_138140298 1.877 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr4_-_154636831 1.866 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chrX_+_96455359 1.857 ENSMUST00000033553.7
Heph
hephaestin
chr11_-_115813621 1.856 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr6_+_134929089 1.844 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr3_+_94933041 1.784 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr1_-_53785214 1.761 ENSMUST00000027263.7
Stk17b
serine/threonine kinase 17b (apoptosis-inducing)
chr12_+_109459843 1.732 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr5_-_21701332 1.710 ENSMUST00000115217.1
ENSMUST00000060899.8
Napepld

N-acyl phosphatidylethanolamine phospholipase D

chr10_-_92162753 1.703 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr7_+_136894598 1.633 ENSMUST00000081510.2
Mgmt
O-6-methylguanine-DNA methyltransferase
chr15_-_10470490 1.627 ENSMUST00000136591.1
Dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr11_-_69900886 1.618 ENSMUST00000108621.2
ENSMUST00000100969.2
2810408A11Rik

RIKEN cDNA 2810408A11 gene

chr15_-_58034289 1.609 ENSMUST00000100655.3
9130401M01Rik
RIKEN cDNA 9130401M01 gene
chr14_-_31640878 1.561 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr11_+_3514861 1.558 ENSMUST00000094469.4
Selm
selenoprotein M
chr6_-_94700137 1.550 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr7_+_79500081 1.545 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr7_-_132813799 1.517 ENSMUST00000097998.2
Fam53b
family with sequence similarity 53, member B
chrX_-_53269020 1.512 ENSMUST00000114838.1
Fam122b
family with sequence similarity 122, member B
chr7_-_141443314 1.510 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr4_-_34730157 1.504 ENSMUST00000108136.1
ENSMUST00000137514.1
ENSMUST00000029971.5
1700003M02Rik


RIKEN cDNA 1700003M02 gene


chr14_+_70774304 1.489 ENSMUST00000022698.7
Dok2
docking protein 2
chr2_-_60963192 1.484 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr7_-_115824699 1.477 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr18_-_77767752 1.466 ENSMUST00000048192.7
Haus1
HAUS augmin-like complex, subunit 1
chr17_-_28350600 1.466 ENSMUST00000114799.1
Tead3
TEA domain family member 3
chr7_-_19698206 1.450 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr7_-_144939823 1.447 ENSMUST00000093962.4
Ccnd1
cyclin D1
chrX_+_169685191 1.425 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr19_+_55894508 1.372 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr5_+_64812336 1.367 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr4_-_55532453 1.366 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr9_-_123678782 1.365 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr16_-_44027938 1.362 ENSMUST00000114677.1
Gramd1c
GRAM domain containing 1C
chr9_-_13818665 1.358 ENSMUST00000150893.1
ENSMUST00000124883.1
Cep57

centrosomal protein 57

chr7_-_28302238 1.354 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr4_-_42168603 1.346 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr5_+_139423151 1.329 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr13_-_81633119 1.328 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr17_+_84511832 1.322 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr11_-_84068357 1.304 ENSMUST00000100705.4
Dusp14
dual specificity phosphatase 14
chr14_-_122913085 1.300 ENSMUST00000162164.1
ENSMUST00000110679.2
ENSMUST00000038075.5
Ggact


gamma-glutamylamine cyclotransferase


chrX_+_139210031 1.297 ENSMUST00000113043.1
ENSMUST00000169886.1
ENSMUST00000113045.2
Mum1l1


melanoma associated antigen (mutated) 1-like 1


chr9_+_123478693 1.295 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chr11_+_32205483 1.283 ENSMUST00000121182.1
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
chr10_+_22360552 1.277 ENSMUST00000182677.1
Raet1d
retinoic acid early transcript delta
chr2_+_144270900 1.276 ENSMUST00000028910.2
ENSMUST00000110027.1
Mgme1

mitochondrial genome maintainance exonuclease 1

chrX_+_75095854 1.273 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chr18_-_39487096 1.272 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr7_-_105787567 1.269 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr10_+_22158566 1.262 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr7_-_19573379 1.257 ENSMUST00000119912.1
Gemin7
gem (nuclear organelle) associated protein 7
chr17_-_31637135 1.257 ENSMUST00000118504.1
ENSMUST00000078509.5
ENSMUST00000067801.6
Cbs


cystathionine beta-synthase


chr6_+_7555053 1.253 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr5_+_64092925 1.230 ENSMUST00000087324.5
Pgm1
phosphoglucomutase 1
chr17_-_57078490 1.226 ENSMUST00000011623.7
Dennd1c
DENN/MADD domain containing 1C
chr7_+_79500018 1.224 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr4_-_132510493 1.224 ENSMUST00000030724.8
Sesn2
sestrin 2
chr7_-_132813528 1.221 ENSMUST00000097999.2
Fam53b
family with sequence similarity 53, member B
chr4_-_41503046 1.217 ENSMUST00000054920.4
AI464131
expressed sequence AI464131
chr10_-_128176568 1.216 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr12_-_69228167 1.216 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chrX_-_48034842 1.209 ENSMUST00000039026.7
Apln
apelin
chr4_+_84884276 1.207 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chr19_-_29325313 1.207 ENSMUST00000052380.4
Insl6
insulin-like 6
chr11_-_84068554 1.204 ENSMUST00000164891.1
Dusp14
dual specificity phosphatase 14
chr2_-_80447625 1.198 ENSMUST00000028389.3
Frzb
frizzled-related protein
chr7_+_27486910 1.192 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr19_-_57008187 1.190 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr2_+_103970115 1.186 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr3_-_66296807 1.184 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr18_+_82914632 1.180 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr19_-_10203880 1.174 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr1_+_97770158 1.171 ENSMUST00000112844.3
ENSMUST00000112842.1
ENSMUST00000027571.6
Gin1


gypsy retrotransposon integrase 1


chr10_+_93641041 1.168 ENSMUST00000020204.4
Ntn4
netrin 4
chr4_-_58499398 1.156 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr3_+_127553462 1.152 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr8_-_84662841 1.140 ENSMUST00000060427.4
Ier2
immediate early response 2
chr9_-_95845215 1.140 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr17_+_6978860 1.137 ENSMUST00000089119.5
ENSMUST00000179728.1
Rnaset2b

ribonuclease T2B

chr8_-_61902669 1.134 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr1_+_12692430 1.126 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr7_-_44816586 1.123 ENSMUST00000047356.8
Atf5
activating transcription factor 5
chr14_+_47373813 1.117 ENSMUST00000142734.1
ENSMUST00000150290.1
ENSMUST00000144794.1
ENSMUST00000146468.1
Lgals3



lectin, galactose binding, soluble 3



chr4_+_84884418 1.113 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chrX_-_162829379 1.112 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
Txlng


taxilin gamma


chr4_+_148130883 1.109 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr5_+_91517615 1.107 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr10_-_10558199 1.105 ENSMUST00000019974.3
Rab32
RAB32, member RAS oncogene family
chr17_+_34263209 1.098 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr2_-_33942111 1.097 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr11_+_69913888 1.092 ENSMUST00000072581.2
ENSMUST00000116358.1
Gps2

G protein pathway suppressor 2

chr4_+_116596672 1.091 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chrY_+_897782 1.089 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr10_+_88147061 1.086 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr10_-_127534540 1.085 ENSMUST00000095266.2
Nxph4
neurexophilin 4
chr1_+_6487231 1.084 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr3_+_90231588 1.078 ENSMUST00000029546.8
ENSMUST00000119304.1
Jtb

jumping translocation breakpoint

chr5_+_110330697 1.077 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr1_+_63273261 1.072 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chr14_+_75845093 1.069 ENSMUST00000110894.2
Tpt1
tumor protein, translationally-controlled 1
chr7_-_116198487 1.067 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr2_+_20519776 1.067 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chr11_+_119913423 1.047 ENSMUST00000132197.1
Chmp6
charged multivesicular body protein 6
chr7_-_4063195 1.025 ENSMUST00000068865.5
ENSMUST00000086400.6
Lair1

leukocyte-associated Ig-like receptor 1

chr19_+_16435616 1.023 ENSMUST00000025602.2
Gna14
guanine nucleotide binding protein, alpha 14
chr11_-_120731944 1.022 ENSMUST00000154565.1
ENSMUST00000026148.2
Cbr2

carbonyl reductase 2

chr15_+_79892436 1.016 ENSMUST00000175752.1
ENSMUST00000176325.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr6_-_28261907 1.016 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr1_-_155527083 1.008 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr11_+_108682602 1.000 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr17_-_49564262 0.998 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chr11_-_6274830 0.997 ENSMUST00000132147.1
ENSMUST00000004508.6
Tmed4

transmembrane emp24 protein transport domain containing 4

chr2_-_51149100 0.997 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr3_+_122924353 0.991 ENSMUST00000106429.3
1810037I17Rik
RIKEN cDNA 1810037I17 gene
chr8_-_115707778 0.989 ENSMUST00000109104.1
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr9_-_48480540 0.988 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr11_+_84957775 0.988 ENSMUST00000103194.3
Car4
carbonic anhydrase 4
chr14_+_14012491 0.985 ENSMUST00000022257.2
Atxn7
ataxin 7
chr4_-_45320580 0.978 ENSMUST00000030003.3
Exosc3
exosome component 3
chr15_+_79892397 0.974 ENSMUST00000175714.1
ENSMUST00000109620.3
ENSMUST00000165537.1
Apobec3


apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3


chr7_-_127993831 0.969 ENSMUST00000033056.3
Pycard
PYD and CARD domain containing
chrM_+_7759 0.965 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr5_+_3571664 0.962 ENSMUST00000008451.5
1700109H08Rik
RIKEN cDNA 1700109H08 gene
chr7_-_126625676 0.954 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr3_-_106014630 0.950 ENSMUST00000010280.4
Pifo
primary cilia formation
chr16_+_17276291 0.944 ENSMUST00000164950.1
ENSMUST00000159242.1
Tmem191c

transmembrane protein 191C

chr4_+_146449023 0.943 ENSMUST00000105733.2
Gm13251
predicted gene 13251
chr14_-_34374617 0.941 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr11_-_84069179 0.939 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr3_+_90514435 0.936 ENSMUST00000048138.6
ENSMUST00000181271.1
S100a13

S100 calcium binding protein A13

chr18_+_67289235 0.923 ENSMUST00000025403.6
Impa2
inositol (myo)-1(or 4)-monophosphatase 2
chr6_+_17281304 0.918 ENSMUST00000115459.1
ENSMUST00000115462.1
Cav2

caveolin 2

chr7_-_29281977 0.913 ENSMUST00000098604.4
ENSMUST00000108236.3
Spint2

serine protease inhibitor, Kunitz type 2

chr6_+_79818031 0.912 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr12_-_111813834 0.911 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr6_+_48647224 0.907 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr3_+_107896247 0.907 ENSMUST00000169365.1
Gstm5
glutathione S-transferase, mu 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.5 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
2.3 6.9 GO:0030421 defecation(GO:0030421)
1.9 7.7 GO:0030091 protein repair(GO:0030091)
1.2 3.7 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
1.2 1.2 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
1.1 3.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.1 5.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.9 3.8 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.9 5.3 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.7 0.7 GO:1900673 olefin metabolic process(GO:1900673)
0.7 2.8 GO:0032610 interleukin-1 alpha production(GO:0032610)
0.7 4.0 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.6 3.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 3.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.5 1.6 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.5 1.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.5 1.5 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.5 1.9 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.5 1.4 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 1.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.4 1.3 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.4 1.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.4 7.8 GO:0060134 prepulse inhibition(GO:0060134)
0.4 2.5 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.4 1.3 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.4 2.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.4 1.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 1.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.4 3.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.4 1.1 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.4 1.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 1.1 GO:0045004 DNA replication proofreading(GO:0045004)
0.3 1.7 GO:1903998 regulation of eating behavior(GO:1903998)
0.3 1.0 GO:0006116 NADH oxidation(GO:0006116)
0.3 2.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.3 1.6 GO:1903232 melanosome assembly(GO:1903232)
0.3 1.0 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.3 1.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 2.5 GO:0040031 snRNA modification(GO:0040031)
0.3 3.4 GO:0051255 spindle midzone assembly(GO:0051255)
0.3 0.9 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 2.4 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.3 1.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 1.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.3 1.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.4 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.3 1.9 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.3 0.8 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 1.9 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.3 1.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 1.4 GO:0007386 compartment pattern specification(GO:0007386)
0.3 1.3 GO:0002339 B cell selection(GO:0002339)
0.3 1.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.3 0.8 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 1.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 1.3 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 0.8 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.2 0.7 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.2 0.7 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.2 1.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 1.9 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 1.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 1.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 0.7 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.7 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 0.8 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 0.6 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 1.9 GO:0071493 cellular response to UV-B(GO:0071493)
0.2 1.9 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.2 1.4 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 1.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 1.2 GO:0015074 DNA integration(GO:0015074)
0.2 1.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.2 0.8 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 0.2 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858)
0.2 0.6 GO:0014028 notochord formation(GO:0014028) negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.7 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 1.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.5 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.2 5.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 0.5 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.2 1.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.8 GO:0072675 osteoclast fusion(GO:0072675)
0.2 1.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 1.5 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 2.3 GO:0035994 response to muscle stretch(GO:0035994)
0.2 0.6 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.2 1.3 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 1.5 GO:0015838 amino-acid betaine transport(GO:0015838)
0.2 1.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 0.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 3.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 1.0 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.6 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 2.0 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 1.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.4 GO:0018094 protein polyglycylation(GO:0018094)
0.1 2.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.1 1.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.7 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.9 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.4 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.1 1.7 GO:0072189 ureter development(GO:0072189)
0.1 0.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 2.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.2 GO:0006303 non-recombinational repair(GO:0000726) double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 1.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.9 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 3.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.3 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 1.0 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.7 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 2.5 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 0.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.3 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.1 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.9 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.8 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.1 0.7 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 4.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.5 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.7 GO:0044241 lipid digestion(GO:0044241)
0.1 2.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 2.9 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 1.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.3 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 1.2 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.1 0.8 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.5 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.7 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 0.3 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.1 1.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.7 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 1.9 GO:0006825 copper ion transport(GO:0006825)
0.1 0.7 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.1 1.3 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.4 GO:0034453 microtubule anchoring(GO:0034453)
0.1 2.8 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.6 GO:0006833 water transport(GO:0006833)
0.1 0.2 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.6 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.4 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.5 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
0.1 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 1.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.2 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.8 GO:0006953 acute-phase response(GO:0006953)
0.1 1.6 GO:0009409 response to cold(GO:0009409)
0.1 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 1.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.8 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 2.8 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.3 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 1.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.3 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 2.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 2.6 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.9 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.7 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.8 GO:1901984 negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.6 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.1 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 1.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 3.4 GO:0051297 centrosome cycle(GO:0007098) centrosome organization(GO:0051297)
0.0 0.7 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.5 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.5 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.8 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.7 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.0 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 1.0 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.7 GO:0034205 beta-amyloid formation(GO:0034205)
0.0 0.2 GO:0097501 stress response to metal ion(GO:0097501)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.8 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 1.4 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0071265 methionine metabolic process(GO:0006555) methionine biosynthetic process(GO:0009086) L-methionine biosynthetic process(GO:0071265)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.8 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0045605 negative regulation of epidermal cell differentiation(GO:0045605)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.7 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 0.2 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.5 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.5 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:1901623 regulation of lymphocyte chemotaxis(GO:1901623)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
0.0 0.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.8 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.5 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 2.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0043488 regulation of RNA stability(GO:0043487) regulation of mRNA stability(GO:0043488)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0030539 male genitalia development(GO:0030539)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0071166 ribonucleoprotein complex localization(GO:0071166) ribonucleoprotein complex export from nucleus(GO:0071426)
0.0 1.2 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0001798 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type II hypersensitivity(GO:0002445) positive regulation of inflammatory response to antigenic stimulus(GO:0002863) positive regulation of acute inflammatory response to antigenic stimulus(GO:0002866) positive regulation of hypersensitivity(GO:0002885) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894) type I hypersensitivity(GO:0016068)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.1 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:0070633 transepithelial transport(GO:0070633)
0.0 0.3 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.1 GO:0007602 phototransduction(GO:0007602)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.6 1.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 3.5 GO:0031262 Ndc80 complex(GO:0031262)
0.5 1.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5 2.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.5 1.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.5 1.4 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.5 6.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 3.6 GO:0070652 HAUS complex(GO:0070652)
0.4 5.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.4 2.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 2.3 GO:0035976 AP1 complex(GO:0035976)
0.3 3.5 GO:0005915 zonula adherens(GO:0005915)
0.3 1.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 2.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 0.8 GO:0044299 C-fiber(GO:0044299)
0.3 3.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 1.0 GO:0061702 inflammasome complex(GO:0061702)
0.2 1.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.1 GO:1990357 terminal web(GO:1990357)
0.2 1.1 GO:0005861 troponin complex(GO:0005861)
0.2 1.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.2 0.8 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.2 1.0 GO:0097441 basilar dendrite(GO:0097441)
0.2 0.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 0.5 GO:0005584 collagen type I trimer(GO:0005584)
0.2 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.8 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 1.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.1 GO:0045298 tubulin complex(GO:0045298)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 5.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 2.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.9 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.4 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.3 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.1 3.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.7 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.8 GO:0032433 filopodium tip(GO:0032433)
0.1 5.3 GO:0005604 basement membrane(GO:0005604)
0.1 0.4 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.1 GO:0097386 glial cell projection(GO:0097386)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 2.6 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 3.5 GO:0005814 centriole(GO:0005814)
0.0 6.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.7 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.5 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 5.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 9.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 3.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0000791 euchromatin(GO:0000791)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 3.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)
0.0 2.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.9 GO:0000793 condensed chromosome(GO:0000793)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.0 4.0 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.8 2.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.8 2.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.7 3.7 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.7 2.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6 2.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.6 1.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.6 3.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.5 1.6 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.5 2.5 GO:0043515 kinetochore binding(GO:0043515)
0.5 1.5 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 2.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.4 2.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.4 1.3 GO:0005118 sevenless binding(GO:0005118)
0.4 1.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.4 3.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.4 3.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.4 2.4 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.4 4.2 GO:0008430 selenium binding(GO:0008430)
0.4 1.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.4 5.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 1.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 1.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.3 1.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.3 4.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.3 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 2.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 2.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 2.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 3.5 GO:0070097 delta-catenin binding(GO:0070097)
0.3 1.1 GO:0019863 IgE binding(GO:0019863) Fc-gamma receptor I complex binding(GO:0034988)
0.3 3.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 1.3 GO:1990239 steroid hormone binding(GO:1990239)
0.3 2.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.7 GO:0071723 lipopeptide binding(GO:0071723)
0.2 0.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 1.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 9.4 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.7 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 1.1 GO:0031014 troponin T binding(GO:0031014)
0.2 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.9 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.2 0.6 GO:0030629 U6 snRNA 3'-end binding(GO:0030629)
0.2 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.2 GO:0070728 leucine binding(GO:0070728)
0.2 0.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 0.9 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 1.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 3.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 1.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 2.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 4.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 0.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 0.6 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 1.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.4 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.5 GO:0019864 immunoglobulin receptor activity(GO:0019763) IgG receptor activity(GO:0019770) IgG binding(GO:0019864)
0.1 1.3 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.2 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 2.0 GO:0051400 BH domain binding(GO:0051400)
0.1 2.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.7 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.1 7.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 1.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.1 2.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.9 GO:0015250 water channel activity(GO:0015250)
0.1 4.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.3 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.5 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 2.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 1.1 GO:0004540 ribonuclease activity(GO:0004540)
0.1 2.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 5.8 GO:0008083 growth factor activity(GO:0008083)
0.1 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 4.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 1.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 2.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 2.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 1.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 1.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 2.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 1.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.7 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.8 GO:0048029 monosaccharide binding(GO:0048029)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 1.0 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 11.6 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.3 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.3 1.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 2.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 6.9 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 1.9 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 6.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 3.1 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 8.0 PID_PLK1_PATHWAY PLK1 signaling events
0.1 12.1 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 3.4 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.7 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.9 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 1.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.8 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 2.4 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.0 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.5 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.9 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.4 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.3 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.5 PID_MYC_PATHWAY C-MYC pathway
0.0 0.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 2.1 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.8 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 3.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.8 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.4 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3 3.1 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 2.2 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 2.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 1.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 1.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.4 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.8 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 1.4 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.4 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.0 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.9 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.0 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.3 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.9 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 5.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.8 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.1 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 2.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.1 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 2.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.1 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 0.6 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 1.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.7 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.8 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.7 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.5 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.2 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 2.9 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 3.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 2.6 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.8 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 1.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0 0.6 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.4 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.8 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.2 REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.1 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.2 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors