Motif ID: Tbx1_Eomes
Z-value: 0.912
Transcription factors associated with Tbx1_Eomes:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Eomes | ENSMUSG00000032446.8 | Eomes |
Tbx1 | ENSMUSG00000009097.9 | Tbx1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Eomes | mm10_v2_chr9_+_118478344_118478451 | 0.55 | 1.5e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 13.1 | GO:0035262 | gonad morphogenesis(GO:0035262) |
2.2 | 26.1 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
2.2 | 6.5 | GO:0032474 | otolith morphogenesis(GO:0032474) |
1.9 | 3.7 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
1.8 | 9.0 | GO:0007386 | compartment pattern specification(GO:0007386) |
1.7 | 6.6 | GO:0051866 | general adaptation syndrome(GO:0051866) |
1.2 | 16.7 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
1.1 | 4.2 | GO:0030091 | protein repair(GO:0030091) |
1.0 | 11.0 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
1.0 | 2.9 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.9 | 1.9 | GO:0036118 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
0.9 | 3.5 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.8 | 7.1 | GO:0071493 | cellular response to UV-B(GO:0071493) |
0.8 | 2.4 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
0.8 | 7.0 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.8 | 2.3 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
0.7 | 8.5 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.6 | 4.8 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
0.5 | 1.9 | GO:0007262 | STAT protein import into nucleus(GO:0007262) |
0.4 | 1.7 | GO:0007412 | axon target recognition(GO:0007412) |
0.4 | 1.3 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.4 | 0.4 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
0.3 | 1.3 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.3 | 2.7 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.3 | 3.0 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.3 | 1.0 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.3 | 10.5 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.3 | 3.1 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
0.2 | 0.7 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.2 | 1.2 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
0.2 | 3.7 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.2 | 0.7 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
0.2 | 0.8 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.2 | 4.5 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.2 | 0.6 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.2 | 6.7 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.2 | 4.5 | GO:0007340 | acrosome reaction(GO:0007340) |
0.2 | 0.5 | GO:2000812 | response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812) |
0.2 | 3.1 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.2 | 0.6 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.1 | 0.4 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.1 | 0.7 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.1 | 0.4 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
0.1 | 1.7 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
0.1 | 0.9 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.1 | 0.5 | GO:0032055 | negative regulation of translation in response to stress(GO:0032055) |
0.1 | 0.6 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.1 | 1.1 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.1 | 0.4 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
0.1 | 0.6 | GO:0030035 | microspike assembly(GO:0030035) |
0.1 | 1.1 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
0.1 | 0.8 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) |
0.1 | 0.5 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.1 | 0.6 | GO:0071384 | cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385) |
0.1 | 13.1 | GO:0050807 | regulation of synapse organization(GO:0050807) |
0.1 | 2.7 | GO:0035411 | catenin import into nucleus(GO:0035411) |
0.1 | 0.6 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) snRNA modification(GO:0040031) |
0.1 | 1.0 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.1 | 0.4 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
0.1 | 0.3 | GO:0051697 | protein delipidation(GO:0051697) |
0.0 | 0.2 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
0.0 | 0.3 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
0.0 | 0.9 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 1.4 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 2.4 | GO:0008347 | glial cell migration(GO:0008347) |
0.0 | 0.4 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.0 | 0.3 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 0.4 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.0 | 6.4 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
0.0 | 0.9 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
0.0 | 0.9 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 0.5 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.0 | 0.2 | GO:0051189 | molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.0 | 0.4 | GO:0016926 | protein desumoylation(GO:0016926) |
0.0 | 0.2 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.0 | 0.3 | GO:2000035 | regulation of stem cell division(GO:2000035) |
0.0 | 1.2 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
0.0 | 1.2 | GO:0021884 | forebrain neuron development(GO:0021884) |
0.0 | 0.9 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.0 | 0.8 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.0 | 0.1 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
0.0 | 0.2 | GO:0006337 | nucleosome disassembly(GO:0006337) |
0.0 | 0.2 | GO:0060965 | negative regulation of gene silencing by miRNA(GO:0060965) |
0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 0.0 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
0.0 | 0.2 | GO:0046697 | decidualization(GO:0046697) |
0.0 | 0.1 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
0.0 | 0.1 | GO:1900116 | sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.0 | 0.2 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.0 | 1.7 | GO:0051291 | protein heterooligomerization(GO:0051291) |
0.0 | 0.2 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
0.0 | 1.0 | GO:2000177 | regulation of neural precursor cell proliferation(GO:2000177) |
0.0 | 0.6 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 7.1 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.8 | 4.5 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.6 | 1.7 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
0.5 | 3.5 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.5 | 2.4 | GO:1990357 | terminal web(GO:1990357) |
0.4 | 16.7 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.4 | 11.0 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.3 | 2.9 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.3 | 0.9 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
0.3 | 1.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.2 | 2.5 | GO:0005916 | fascia adherens(GO:0005916) |
0.2 | 1.2 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.2 | 0.8 | GO:0031983 | vesicle lumen(GO:0031983) |
0.2 | 4.8 | GO:0001741 | XY body(GO:0001741) |
0.1 | 0.6 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
0.1 | 25.3 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.1 | 10.5 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 0.5 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.1 | 1.7 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.1 | 0.9 | GO:0031415 | NatA complex(GO:0031415) |
0.1 | 0.5 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.1 | 0.5 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.1 | 3.1 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.1 | 4.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 7.0 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 3.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.6 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.2 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.0 | 1.2 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 1.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.4 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 0.5 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 6.3 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 1.4 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
0.0 | 0.6 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.1 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 2.6 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 0.0 | GO:0031084 | BLOC-2 complex(GO:0031084) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 7.1 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
2.2 | 11.0 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
1.3 | 6.7 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
1.2 | 3.5 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.9 | 7.0 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.7 | 4.2 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.7 | 10.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.6 | 4.5 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.6 | 1.9 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.6 | 4.8 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.6 | 2.3 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
0.5 | 2.9 | GO:0070728 | leucine binding(GO:0070728) |
0.4 | 1.3 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.4 | 16.7 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.4 | 1.9 | GO:0038132 | neuregulin binding(GO:0038132) |
0.3 | 1.2 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
0.3 | 1.2 | GO:0042806 | fucose binding(GO:0042806) |
0.3 | 1.1 | GO:0050436 | microfibril binding(GO:0050436) |
0.3 | 3.0 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
0.3 | 1.3 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.2 | 9.0 | GO:0005112 | Notch binding(GO:0005112) |
0.2 | 2.1 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.2 | 1.7 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.2 | 2.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.1 | 0.6 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
0.1 | 1.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.1 | 3.7 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.1 | 2.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 0.6 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
0.1 | 20.4 | GO:0001047 | core promoter binding(GO:0001047) |
0.1 | 1.0 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.1 | 0.4 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
0.1 | 1.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.9 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.1 | 0.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 1.1 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.9 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
0.0 | 0.4 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.0 | 0.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.0 | 0.4 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.0 | 0.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 6.1 | GO:0000287 | magnesium ion binding(GO:0000287) |
0.0 | 0.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 3.1 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.0 | 0.1 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.2 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.4 | GO:0008483 | transaminase activity(GO:0008483) |
0.0 | 0.4 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 3.5 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.2 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.0 | 0.7 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 2.0 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.4 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.4 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 2.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.4 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 7.1 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.2 | 2.4 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.1 | 6.5 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.1 | 0.9 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.1 | 9.4 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.1 | 3.5 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.1 | 2.7 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 2.4 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.1 | 10.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 1.7 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.1 | 3.1 | PID_RHOA_PATHWAY | RhoA signaling pathway |
0.1 | 4.3 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.1 | 3.9 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 0.7 | PID_IL23_PATHWAY | IL23-mediated signaling events |
0.0 | 2.1 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 1.2 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
0.0 | 2.1 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 0.3 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 0.2 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 1.0 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.3 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 1.0 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
0.0 | 0.4 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.4 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.7 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.3 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 1.9 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.3 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 11.0 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.3 | 1.3 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
0.3 | 7.1 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.2 | 2.4 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.2 | 2.4 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.2 | 6.5 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.2 | 1.9 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
0.1 | 1.7 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.1 | 15.7 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
0.1 | 3.7 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.1 | 2.7 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.1 | 2.9 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.1 | 0.7 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
0.1 | 1.0 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.1 | 2.1 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.9 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 2.2 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.3 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.0 | 1.2 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 0.8 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 1.5 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.4 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 4.4 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 0.4 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.3 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
0.0 | 0.3 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.4 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 1.2 | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | Genes involved in Cell surface interactions at the vascular wall |
0.0 | 1.7 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
0.0 | 0.6 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |