Motif ID: Tbx3

Z-value: 0.279


Transcription factors associated with Tbx3:

Gene SymbolEntrez IDGene Name
Tbx3 ENSMUSG00000018604.12 Tbx3



Activity profile for motif Tbx3.

activity profile for motif Tbx3


Sorted Z-values histogram for motif Tbx3

Sorted Z-values for motif Tbx3



Network of associatons between targets according to the STRING database.



Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_100970887 1.178 ENSMUST00000060792.5
Ptrf
polymerase I and transcript release factor
chr19_+_7056731 0.907 ENSMUST00000040261.5
Macrod1
MACRO domain containing 1
chr10_-_18743691 0.647 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr7_-_4522427 0.646 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr7_+_112374839 0.604 ENSMUST00000106645.1
Micalcl
MICAL C-terminal like
chr5_-_106926245 0.399 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr11_-_94507337 0.398 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chr7_-_4522794 0.369 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr1_-_31222604 0.364 ENSMUST00000127775.1
4931428L18Rik
RIKEN cDNA 4931428L18 gene
chr18_-_23981555 0.340 ENSMUST00000115829.1
Zscan30
zinc finger and SCAN domain containing 30
chr7_+_107567445 0.305 ENSMUST00000120990.1
Olfml1
olfactomedin-like 1
chr12_+_84361636 0.254 ENSMUST00000110276.1
Coq6
coenzyme Q6 homolog (yeast)
chr12_+_84362029 0.243 ENSMUST00000110278.1
ENSMUST00000145522.1
Coq6

coenzyme Q6 homolog (yeast)

chr12_+_84361968 0.221 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr12_-_84361802 0.214 ENSMUST00000021659.1
ENSMUST00000065536.2
Fam161b

family with sequence similarity 161, member B

chr19_+_7494033 0.194 ENSMUST00000170373.1
Atl3
atlastin GTPase 3
chr1_+_93215899 0.166 ENSMUST00000138595.1
E030010N08Rik
RIKEN cDNA E030010N08 gene
chr10_+_127514939 0.153 ENSMUST00000035735.9
Ndufa4l2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr7_-_118443549 0.045 ENSMUST00000081574.4
Syt17
synaptotagmin XVII
chr3_-_89245829 0.039 ENSMUST00000041022.8
Trim46
tripartite motif-containing 46
chrX_-_20931520 0.021 ENSMUST00000001156.7
Cfp
complement factor properdin
chr7_-_44236098 0.021 ENSMUST00000037220.4
1700028J19Rik
RIKEN cDNA 1700028J19 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 1.0 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.7 GO:0071949 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) FAD binding(GO:0071949)
0.0 0.9 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction