Motif ID: Tfap2a

Z-value: 1.061


Transcription factors associated with Tfap2a:

Gene SymbolEntrez IDGene Name
Tfap2a ENSMUSG00000021359.9 Tfap2a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2amm10_v2_chr13_-_40730416_407304290.104.7e-01Click!


Activity profile for motif Tfap2a.

activity profile for motif Tfap2a


Sorted Z-values histogram for motif Tfap2a

Sorted Z-values for motif Tfap2a



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_100015817 8.178 ENSMUST00000130190.1
ENSMUST00000020129.7
Kitl

kit ligand

chr1_+_159737510 7.785 ENSMUST00000111669.3
Tnr
tenascin R
chr5_-_146585239 7.612 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12
chr10_-_86498836 7.222 ENSMUST00000120638.1
Syn3
synapsin III
chr9_+_21184103 7.108 ENSMUST00000115458.2
Pde4a
phosphodiesterase 4A, cAMP specific
chr17_+_69969073 6.883 ENSMUST00000133983.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr17_+_69969387 6.700 ENSMUST00000146730.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr17_+_69969217 6.378 ENSMUST00000060072.5
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr8_+_70493156 5.745 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr9_+_26733728 5.600 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr11_+_32296489 5.398 ENSMUST00000093207.3
Hba-a2
hemoglobin alpha, adult chain 2
chr12_-_67221221 5.106 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr9_+_109931774 4.762 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr10_+_86021961 4.713 ENSMUST00000130320.1
Fbxo7
F-box protein 7
chr12_-_76822510 4.696 ENSMUST00000021459.7
Rab15
RAB15, member RAS oncogene family
chr13_-_110280103 4.335 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chrX_-_162643629 4.328 ENSMUST00000112334.1
Reps2
RALBP1 associated Eps domain containing protein 2
chrX_-_162643575 4.320 ENSMUST00000101102.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr15_-_45114926 4.199 ENSMUST00000022967.5
Kcnv1
potassium channel, subfamily V, member 1
chr12_+_40446050 4.107 ENSMUST00000037488.6
Dock4
dedicator of cytokinesis 4
chr17_-_29237759 3.954 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr5_+_117841839 3.944 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr2_-_163918683 3.888 ENSMUST00000044734.2
Rims4
regulating synaptic membrane exocytosis 4
chr10_-_86498872 3.878 ENSMUST00000121789.1
Syn3
synapsin III
chr19_+_42255704 3.845 ENSMUST00000087123.5
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr1_-_38836090 3.838 ENSMUST00000147695.1
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr13_+_54949388 3.674 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr13_-_98206151 3.665 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr14_-_102982630 3.565 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr10_+_81575306 3.501 ENSMUST00000146916.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr1_-_190979280 3.490 ENSMUST00000166139.1
Vash2
vasohibin 2
chr14_+_68083853 3.466 ENSMUST00000022639.7
Nefl
neurofilament, light polypeptide
chr10_+_79716588 3.463 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr9_+_26733845 3.412 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr4_-_149698552 3.397 ENSMUST00000134534.1
ENSMUST00000146612.1
ENSMUST00000105688.3
Pik3cd


phosphatidylinositol 3-kinase catalytic delta polypeptide


chr4_-_136956784 3.390 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr4_-_149698698 3.296 ENSMUST00000038859.7
ENSMUST00000105690.2
Pik3cd

phosphatidylinositol 3-kinase catalytic delta polypeptide

chr19_-_28911879 3.214 ENSMUST00000179171.1
AC163993.1
AC163993.1
chr7_+_121392266 3.200 ENSMUST00000084628.3
Hs3st2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr18_+_37955126 3.069 ENSMUST00000176902.1
ENSMUST00000176104.1
Rell2

RELT-like 2

chr9_-_112187898 2.978 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr2_+_118779703 2.885 ENSMUST00000063975.3
ENSMUST00000037547.2
ENSMUST00000110846.1
ENSMUST00000110843.1
Disp2



dispatched homolog 2 (Drosophila)



chr11_+_62575981 2.686 ENSMUST00000102643.1
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr6_-_137649211 2.680 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
Eps8


epidermal growth factor receptor pathway substrate 8


chr6_-_37299950 2.679 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr4_+_43401232 2.674 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr10_+_81575257 2.670 ENSMUST00000135211.1
Tle2
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr6_-_124769548 2.644 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr9_+_89909775 2.643 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr1_-_193370225 2.626 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr7_+_6415164 2.624 ENSMUST00000160218.1
Smim17
small integral membrane protein 17
chr4_-_64046925 2.614 ENSMUST00000107377.3
Tnc
tenascin C
chr3_+_26331150 2.574 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr1_-_193370260 2.537 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr16_+_20589471 2.529 ENSMUST00000100074.3
ENSMUST00000096197.4
Vwa5b2

von Willebrand factor A domain containing 5B2

chr16_-_97170707 2.502 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr9_+_34904913 2.495 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr18_-_38601268 2.471 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr7_-_65156416 2.468 ENSMUST00000148459.1
ENSMUST00000119118.1
Fam189a1

family with sequence similarity 189, member A1

chr3_-_94786469 2.467 ENSMUST00000107273.1
Cgn
cingulin
chr4_+_43383449 2.454 ENSMUST00000135216.1
ENSMUST00000152322.1
Rusc2

RUN and SH3 domain containing 2

chr4_+_85205120 2.419 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr19_+_46761578 2.391 ENSMUST00000077666.4
ENSMUST00000099373.4
Cnnm2

cyclin M2

chr9_+_21165714 2.338 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr14_-_29721835 2.338 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr4_+_43381979 2.317 ENSMUST00000035645.5
ENSMUST00000144911.1
Rusc2

RUN and SH3 domain containing 2

chr11_+_103101682 2.286 ENSMUST00000107040.3
ENSMUST00000140372.1
ENSMUST00000024492.8
ENSMUST00000134884.1
Acbd4



acyl-Coenzyme A binding domain containing 4



chr15_-_37791993 2.281 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr14_+_70553687 2.209 ENSMUST00000161069.1
Hr
hairless
chr2_-_32312162 2.190 ENSMUST00000155269.1
Dnm1
dynamin 1
chr1_-_190978954 2.170 ENSMUST00000047409.6
Vash2
vasohibin 2
chr5_-_32746317 2.157 ENSMUST00000135248.1
Pisd
phosphatidylserine decarboxylase
chr3_-_30969399 2.157 ENSMUST00000177992.1
ENSMUST00000129817.2
ENSMUST00000168645.1
ENSMUST00000108255.1
ENSMUST00000064718.5
ENSMUST00000099163.3
Phc3





polyhomeotic-like 3 (Drosophila)





chr11_+_117654211 2.095 ENSMUST00000026658.6
Tnrc6c
trinucleotide repeat containing 6C
chr1_+_132880273 2.091 ENSMUST00000027706.3
Lrrn2
leucine rich repeat protein 2, neuronal
chr5_-_67847400 2.063 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
Atp8a1


ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1


chr7_-_98178254 2.061 ENSMUST00000040971.7
Capn5
calpain 5
chr11_+_46055973 2.036 ENSMUST00000011400.7
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr5_-_24030297 2.035 ENSMUST00000101513.2
Fam126a
family with sequence similarity 126, member A
chr1_-_54194048 2.030 ENSMUST00000120904.1
Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr13_-_101768154 2.026 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr18_+_34220978 2.021 ENSMUST00000079362.5
ENSMUST00000115781.3
Apc

adenomatosis polyposis coli

chr11_-_121388186 1.981 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chrX_-_8206475 1.974 ENSMUST00000089403.3
ENSMUST00000077595.5
ENSMUST00000089402.3
ENSMUST00000082320.5
Porcn



porcupine homolog (Drosophila)



chr9_-_97111117 1.974 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36
chr2_+_121358591 1.971 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr5_-_113310729 1.969 ENSMUST00000112325.1
ENSMUST00000048112.6
Sgsm1

small G protein signaling modulator 1

chr13_+_109632760 1.954 ENSMUST00000135275.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr16_+_93832121 1.947 ENSMUST00000044068.6
Morc3
microrchidia 3
chr19_+_10041548 1.947 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr15_+_79108911 1.926 ENSMUST00000040320.8
Micall1
microtubule associated monooxygenase, calponin and LIM domain containing -like 1
chr13_+_24845122 1.922 ENSMUST00000006893.8
D130043K22Rik
RIKEN cDNA D130043K22 gene
chr15_+_25414175 1.912 ENSMUST00000069992.5
Gm5468
predicted gene 5468
chr13_+_96542602 1.907 ENSMUST00000179226.1
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr15_-_58214882 1.902 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr5_-_103911196 1.894 ENSMUST00000031254.2
Klhl8
kelch-like 8
chr4_-_11966368 1.887 ENSMUST00000056050.4
ENSMUST00000108299.1
ENSMUST00000108297.2
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr7_+_128611328 1.880 ENSMUST00000098007.4
ENSMUST00000043138.6
Inpp5f

inositol polyphosphate-5-phosphatase F

chr12_-_109068173 1.874 ENSMUST00000073156.7
Begain
brain-enriched guanylate kinase-associated
chr3_-_94786430 1.874 ENSMUST00000107272.1
Cgn
cingulin
chr5_-_113310697 1.867 ENSMUST00000154248.1
Sgsm1
small G protein signaling modulator 1
chr12_+_109544498 1.864 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr16_-_34573526 1.853 ENSMUST00000114961.1
Kalrn
kalirin, RhoGEF kinase
chr19_-_45816007 1.847 ENSMUST00000079431.3
ENSMUST00000026247.6
ENSMUST00000162528.2
Kcnip2


Kv channel-interacting protein 2


chr6_-_128143525 1.843 ENSMUST00000032503.5
ENSMUST00000112173.1
Tspan9

tetraspanin 9

chr11_+_70029742 1.820 ENSMUST00000132597.2
Dlg4
discs, large homolog 4 (Drosophila)
chr19_+_5568002 1.816 ENSMUST00000096318.3
Ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr7_-_119184374 1.799 ENSMUST00000084650.4
Gpr139
G protein-coupled receptor 139
chr11_+_32283511 1.794 ENSMUST00000093209.3
Hba-a1
hemoglobin alpha, adult chain 1
chr17_-_24209377 1.792 ENSMUST00000024931.4
Ntn3
netrin 3
chrX_+_93675088 1.788 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr14_+_76476913 1.769 ENSMUST00000140251.2
Tsc22d1
TSC22 domain family, member 1
chr15_-_89128634 1.750 ENSMUST00000082197.5
Hdac10
histone deacetylase 10
chr2_+_29124972 1.739 ENSMUST00000061578.2
Setx
senataxin
chr11_+_3332426 1.731 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr13_+_41249841 1.729 ENSMUST00000165561.2
Smim13
small integral membrane protein 13
chr13_+_96542727 1.726 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr17_+_37046555 1.725 ENSMUST00000172789.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr2_-_146511899 1.723 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr7_-_98656530 1.722 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr2_+_109890846 1.717 ENSMUST00000028583.7
Lin7c
lin-7 homolog C (C. elegans)
chr11_-_116110211 1.712 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr5_+_107437908 1.698 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr11_-_103101609 1.690 ENSMUST00000103077.1
Plcd3
phospholipase C, delta 3
chr11_-_102897123 1.684 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr2_-_73386396 1.682 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
Gpr155


G protein-coupled receptor 155


chr4_-_20778527 1.679 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chrX_-_48208566 1.677 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr4_+_57434247 1.655 ENSMUST00000102905.1
Palm2
paralemmin 2
chrX_-_98890781 1.637 ENSMUST00000113826.1
ENSMUST00000033560.2
ENSMUST00000142267.1
Ophn1


oligophrenin 1


chr7_+_113765998 1.619 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr7_+_16944645 1.618 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chr14_+_33923582 1.611 ENSMUST00000168727.1
Gdf10
growth differentiation factor 10
chr2_-_77816758 1.597 ENSMUST00000111831.1
Zfp385b
zinc finger protein 385B
chr2_-_44927161 1.586 ENSMUST00000130991.1
Gtdc1
glycosyltransferase-like domain containing 1
chr9_-_67043953 1.579 ENSMUST00000113690.1
Tpm1
tropomyosin 1, alpha
chr13_-_54611274 1.578 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr17_-_6449571 1.577 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr5_-_121502980 1.568 ENSMUST00000079368.3
Adam1b
a disintegrin and metallopeptidase domain 1b
chr5_+_75152274 1.556 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr16_-_4003750 1.553 ENSMUST00000171658.1
ENSMUST00000171762.1
Slx4

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

chr11_-_66525964 1.548 ENSMUST00000066679.6
Shisa6
shisa homolog 6 (Xenopus laevis)
chr6_-_60828889 1.540 ENSMUST00000114268.3
Snca
synuclein, alpha
chr16_-_35769356 1.539 ENSMUST00000023554.8
Dirc2
disrupted in renal carcinoma 2 (human)
chr9_+_31280525 1.538 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr2_-_146511992 1.528 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr18_+_62548911 1.523 ENSMUST00000055725.4
ENSMUST00000162365.1
Spink10

serine peptidase inhibitor, Kazal type 10

chr1_+_23762003 1.521 ENSMUST00000140583.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr4_+_125085134 1.519 ENSMUST00000154689.1
ENSMUST00000055213.4
ENSMUST00000106171.2
Meaf6


MYST/Esa1-associated factor 6


chr2_+_145934800 1.515 ENSMUST00000138774.1
ENSMUST00000152515.1
ENSMUST00000130168.1
ENSMUST00000133433.1
ENSMUST00000118002.1
4930529M08Rik




RIKEN cDNA 4930529M08 gene




chr5_-_24030649 1.514 ENSMUST00000030849.6
Fam126a
family with sequence similarity 126, member A
chr5_-_34187670 1.506 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr11_-_103954015 1.503 ENSMUST00000103075.4
Nsf
N-ethylmaleimide sensitive fusion protein
chr6_+_129533183 1.491 ENSMUST00000032264.6
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr18_-_38209762 1.486 ENSMUST00000057185.6
Pcdh1
protocadherin 1
chr2_-_24935148 1.476 ENSMUST00000102935.3
ENSMUST00000133934.1
ENSMUST00000028349.7
Arrdc1


arrestin domain containing 1


chr11_-_102296618 1.474 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr4_-_118179628 1.462 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr10_-_5922385 1.456 ENSMUST00000131996.1
ENSMUST00000064225.7
Rgs17

regulator of G-protein signaling 17

chr2_-_34754364 1.450 ENSMUST00000142436.1
ENSMUST00000113099.3
ENSMUST00000028224.8
Gapvd1


GTPase activating protein and VPS9 domains 1


chr11_-_88863717 1.410 ENSMUST00000107904.2
Akap1
A kinase (PRKA) anchor protein 1
chr3_+_33799791 1.406 ENSMUST00000099153.3
Ttc14
tetratricopeptide repeat domain 14
chr8_+_107293500 1.400 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
Nfat5


nuclear factor of activated T cells 5


chr14_-_66280949 1.392 ENSMUST00000111121.1
ENSMUST00000022622.7
ENSMUST00000089250.2
Ptk2b


PTK2 protein tyrosine kinase 2 beta


chr1_-_75210732 1.392 ENSMUST00000113623.1
Glb1l
galactosidase, beta 1-like
chr6_+_56714891 1.391 ENSMUST00000031805.8
Avl9
AVL9 homolog (S. cerevisiase)
chr1_+_180726019 1.390 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chr1_-_75278345 1.381 ENSMUST00000039534.4
Resp18
regulated endocrine-specific protein 18
chr11_-_95699143 1.363 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr7_+_97842917 1.355 ENSMUST00000033040.5
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr3_-_110142996 1.350 ENSMUST00000156177.2
Ntng1
netrin G1
chr7_+_47050628 1.343 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr16_+_24448082 1.343 ENSMUST00000078988.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr1_-_132741750 1.339 ENSMUST00000094569.4
ENSMUST00000163770.1
Nfasc

neurofascin

chr4_+_42714926 1.301 ENSMUST00000178454.1
Gm21955
predicted gene, 21955
chr2_-_102400863 1.297 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr12_+_24651346 1.297 ENSMUST00000020982.5
Klf11
Kruppel-like factor 11
chr13_-_99516537 1.294 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr11_+_70030023 1.291 ENSMUST00000143920.2
Dlg4
discs, large homolog 4 (Drosophila)
chr17_-_87797994 1.291 ENSMUST00000055221.7
Kcnk12
potassium channel, subfamily K, member 12
chr9_-_59036387 1.277 ENSMUST00000068664.5
Neo1
neogenin
chr9_+_66350465 1.273 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr15_+_25843264 1.271 ENSMUST00000022881.7
Fam134b
family with sequence similarity 134, member B
chr7_+_44590886 1.266 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr6_+_143285988 1.258 ENSMUST00000160951.1
D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chrX_-_150657366 1.257 ENSMUST00000148604.1
Tro
trophinin
chr13_-_49147931 1.253 ENSMUST00000162581.1
ENSMUST00000110097.2
ENSMUST00000049265.8
ENSMUST00000035538.6
ENSMUST00000110096.1
ENSMUST00000091623.3
Wnk2





WNK lysine deficient protein kinase 2





chr3_-_107969162 1.237 ENSMUST00000004136.8
ENSMUST00000106678.1
Gstm3

glutathione S-transferase, mu 3

chr5_-_124249758 1.225 ENSMUST00000162812.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr11_+_75468040 1.220 ENSMUST00000043598.7
ENSMUST00000108435.1
Tlcd2

TLC domain containing 2

chrX_-_103186618 1.218 ENSMUST00000121720.1
Nap1l2
nucleosome assembly protein 1-like 2
chr8_+_85060055 1.212 ENSMUST00000095220.3
Fbxw9
F-box and WD-40 domain protein 9
chr4_+_136310991 1.204 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr7_+_97081711 1.203 ENSMUST00000004622.5
Gab2
growth factor receptor bound protein 2-associated protein 2
chr7_-_45333754 1.202 ENSMUST00000042194.8
Trpm4
transient receptor potential cation channel, subfamily M, member 4
chr18_+_31931470 1.200 ENSMUST00000025254.7
Lims2
LIM and senescent cell antigen like domains 2
chr18_-_16809233 1.197 ENSMUST00000025166.7
Cdh2
cadherin 2
chr19_+_53600377 1.196 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr8_-_126971062 1.194 ENSMUST00000045994.6
Rbm34
RNA binding motif protein 34
chr3_-_152668135 1.191 ENSMUST00000045262.6
Ak5
adenylate kinase 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 8.2 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
1.9 7.8 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.5 20.0 GO:0070842 aggresome assembly(GO:0070842)
1.5 6.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.3 3.9 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
1.2 3.6 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
1.0 4.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
1.0 5.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.0 6.7 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
1.0 2.9 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
1.0 4.8 GO:0051012 microtubule sliding(GO:0051012)
0.7 2.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.7 2.7 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.7 3.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.6 1.9 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.6 3.0 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.6 12.1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.6 1.2 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.6 4.7 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.6 1.7 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.5 1.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.5 1.6 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.5 2.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.5 5.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.5 2.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.5 4.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.5 1.9 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.5 1.4 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.5 2.3 GO:0021764 amygdala development(GO:0021764)
0.5 3.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 1.4 GO:0019858 cytosine metabolic process(GO:0019858)
0.5 4.5 GO:0046959 habituation(GO:0046959)
0.4 0.9 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.4 1.3 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.4 1.9 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.4 1.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.4 1.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 3.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 2.5 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.4 1.1 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.3 2.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 1.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 1.0 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.3 1.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.3 10.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.3 3.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.3 1.0 GO:1905223 epicardium morphogenesis(GO:1905223)
0.3 2.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.3 1.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.3 1.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 2.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 0.9 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.3 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 1.1 GO:0061623 glycolytic process from galactose(GO:0061623)
0.3 0.8 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.3 1.0 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.2 1.7 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 7.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.2 0.7 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.2 3.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 1.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 6.2 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.2 0.2 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324)
0.2 1.8 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.2 2.7 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 1.8 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.2 2.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 1.5 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.2 0.8 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.2 3.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.0 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 0.2 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.2 0.6 GO:0090649 cellular response to manganese ion(GO:0071287) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 0.8 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 0.8 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 0.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 0.7 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 2.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 1.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.5 GO:0019401 alditol biosynthetic process(GO:0019401)
0.2 1.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.2 3.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.2 0.3 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.2 4.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 0.5 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 2.8 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.2 0.6 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 5.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 0.6 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.2 2.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 3.6 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.1 1.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 2.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 2.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.8 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.6 GO:0008355 olfactory learning(GO:0008355)
0.1 0.8 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.1 1.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.7 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.6 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.2 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 1.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 2.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.5 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.1 1.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.3 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 1.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.8 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0008228 opsonization(GO:0008228)
0.1 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.1 4.4 GO:0048821 erythrocyte development(GO:0048821)
0.1 0.5 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 4.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 2.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.6 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.8 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.0 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.1 7.5 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.1 2.0 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.1 1.6 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.2 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 2.6 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.1 0.5 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 5.5 GO:0017157 regulation of exocytosis(GO:0017157)
0.1 1.2 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 3.0 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.6 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 2.5 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 0.5 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.2 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 1.3 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.1 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.1 4.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.6 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 1.3 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 1.8 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 2.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 1.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.8 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 1.0 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.2 GO:0061157 mRNA destabilization(GO:0061157)
0.0 1.0 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.9 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 2.0 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 1.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.9 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 1.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0044804 nucleophagy(GO:0044804)
0.0 1.1 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.5 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.5 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 2.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.7 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 0.8 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 4.3 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0 0.5 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.1 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 1.1 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0033135 regulation of peptidyl-serine phosphorylation(GO:0033135)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.4 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.2 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.7 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 1.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.2 GO:0017145 stem cell division(GO:0017145)
0.0 0.8 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.0 GO:0071499 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046) response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.8 GO:0072534 perineuronal net(GO:0072534)
1.9 5.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.8 7.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.2 3.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.2 3.5 GO:0098855 HCN channel complex(GO:0098855)
0.9 4.7 GO:1990037 Lewy body core(GO:1990037)
0.7 2.8 GO:0097450 astrocyte end-foot(GO:0097450)
0.5 2.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5 5.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.4 4.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 0.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.3 1.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 7.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.3 1.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 0.9 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.3 1.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 2.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 4.4 GO:0043196 varicosity(GO:0043196)
0.3 1.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3 2.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 1.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 2.7 GO:0032584 growth cone membrane(GO:0032584)
0.2 4.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.9 GO:1990745 EARP complex(GO:1990745)
0.2 2.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 2.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 3.1 GO:0044224 juxtaparanode region of axon(GO:0044224) cerebellar mossy fiber(GO:0044300)
0.2 0.6 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.6 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 4.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 3.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 1.4 GO:0071437 invadopodium(GO:0071437)
0.1 1.2 GO:0016342 catenin complex(GO:0016342)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 2.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.2 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.2 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.7 GO:0061689 tricellular tight junction(GO:0061689)
0.1 8.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.5 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.3 GO:0005940 septin ring(GO:0005940)
0.1 4.8 GO:0032420 stereocilium(GO:0032420)
0.1 1.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 3.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.9 GO:0070578 RISC-loading complex(GO:0070578)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 4.4 GO:0016459 myosin complex(GO:0016459)
0.1 9.9 GO:0030175 filopodium(GO:0030175)
0.1 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 3.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.1 GO:0097386 glial cell projection(GO:0097386)
0.1 1.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.4 GO:0031143 pseudopodium(GO:0031143)
0.1 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.1 2.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0031931 TORC1 complex(GO:0031931)
0.1 23.1 GO:0014069 postsynaptic density(GO:0014069)
0.1 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 4.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.2 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.6 GO:0030057 desmosome(GO:0030057)
0.1 1.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.6 GO:0043195 terminal bouton(GO:0043195)
0.1 5.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.0 GO:0000124 SAGA complex(GO:0000124)
0.1 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.1 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 4.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 1.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 2.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 5.7 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0043218 compact myelin(GO:0043218)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 1.4 GO:0005902 microvillus(GO:0005902) actin-based cell projection(GO:0098858)
0.0 9.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0031010 ISWI-type complex(GO:0031010)
0.0 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 3.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0009986 cell surface(GO:0009986)
0.0 0.4 GO:0031201 SNARE complex(GO:0031201)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.2 GO:0034702 ion channel complex(GO:0034702)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.0 GO:0036156 inner dynein arm(GO:0036156)
0.0 1.4 GO:0043209 myelin sheath(GO:0043209)
0.0 4.7 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.0 GO:0005769 early endosome(GO:0005769)
0.0 1.3 GO:0012506 vesicle membrane(GO:0012506)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 5.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 3.5 GO:0005768 endosome(GO:0005768)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.9 GO:0001726 ruffle(GO:0001726)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 12.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.8 7.2 GO:0031720 haptoglobin binding(GO:0031720)
1.4 8.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
1.3 3.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.9 1.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.9 3.5 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.8 6.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.8 5.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.7 11.4 GO:0046625 sphingolipid binding(GO:0046625)
0.6 3.7 GO:0005042 netrin receptor activity(GO:0005042)
0.6 3.6 GO:0045545 syndecan binding(GO:0045545)
0.6 1.7 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.6 1.7 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.6 2.8 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.5 7.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.5 2.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.5 2.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 2.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.5 2.0 GO:0004111 creatine kinase activity(GO:0004111)
0.4 3.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 2.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 1.2 GO:0035500 MH2 domain binding(GO:0035500)
0.4 3.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.4 1.9 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.4 1.1 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.4 1.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 1.0 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 2.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 2.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.3 1.3 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.3 1.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 1.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 1.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 10.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 0.9 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 1.2 GO:0036033 mediator complex binding(GO:0036033)
0.3 2.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.7 GO:0097016 L27 domain binding(GO:0097016)
0.3 1.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.3 1.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.3 1.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 0.8 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 1.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 2.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 1.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 1.0 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.2 3.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 0.6 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 0.6 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 0.6 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.2 3.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 4.3 GO:0031489 myosin V binding(GO:0031489)
0.2 1.1 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.2 0.5 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.2 1.4 GO:0043423 NMDA glutamate receptor activity(GO:0004972) 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 2.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.2 3.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 4.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 1.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 3.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.9 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 3.5 GO:0043274 phospholipase binding(GO:0043274)
0.1 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 2.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 1.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.5 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.7 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 7.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.6 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 1.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 2.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 1.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.1 2.1 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 2.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.9 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.9 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.1 1.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 12.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 6.2 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 5.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 4.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.8 GO:0035198 miRNA binding(GO:0035198)
0.1 1.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 5.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 3.1 GO:0005518 collagen binding(GO:0005518)
0.0 2.7 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 7.0 GO:0003924 GTPase activity(GO:0003924)
0.0 1.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 5.6 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174) mercury ion binding(GO:0045340)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 2.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 2.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.2 5.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 3.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.4 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 4.8 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 2.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 3.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 0.7 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.4 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 3.0 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 2.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.9 PID_ARF_3PATHWAY Arf1 pathway
0.1 6.1 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 0.7 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.1 0.9 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 2.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.0 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.9 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.6 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 2.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 3.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.6 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.9 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.4 12.1 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.3 4.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 9.9 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 3.9 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.3 2.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.2 4.6 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 5.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 2.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 2.9 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 1.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.2 1.6 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.2 2.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.1 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.7 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.0 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 3.8 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.9 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 4.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.8 REACTOME_IL_2_SIGNALING Genes involved in Interleukin-2 signaling
0.1 0.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 2.0 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 4.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.8 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 7.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.6 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.1 3.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.5 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.8 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.1 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.6 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 2.1 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 1.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 2.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 3.6 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 6.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.0 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.9 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 2.7 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.5 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.6 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.9 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.6 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.1 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.4 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases