Motif ID: Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
Z-value: 1.164
Transcription factors associated with Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bhlhe41 | ENSMUSG00000030256.5 | Bhlhe41 |
| Srebf1 | ENSMUSG00000020538.9 | Srebf1 |
| Srebf2 | ENSMUSG00000022463.7 | Srebf2 |
| Tfeb | ENSMUSG00000023990.12 | Tfeb |
| Usf1 | ENSMUSG00000026641.7 | Usf1 |
| Usf2 | ENSMUSG00000058239.7 | Usf2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Srebf1 | mm10_v2_chr11_-_60210410_60210465 | 0.38 | 4.6e-03 | Click! |
| Usf2 | mm10_v2_chr7_-_30956742_30956803 | -0.26 | 5.2e-02 | Click! |
| Usf1 | mm10_v2_chr1_+_171411305_171411337 | 0.18 | 1.9e-01 | Click! |
| Tfeb | mm10_v2_chr17_+_47785720_47785739 | 0.16 | 2.5e-01 | Click! |
| Srebf2 | mm10_v2_chr15_+_82147238_82147275 | 0.15 | 2.7e-01 | Click! |
First level regulatory network of Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
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Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.3 | 25.3 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 3.6 | 10.9 | GO:1904959 | elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
| 2.6 | 10.4 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 2.2 | 6.5 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 2.0 | 6.0 | GO:0099547 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
| 2.0 | 5.9 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
| 1.7 | 6.9 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 1.7 | 5.0 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 1.6 | 6.5 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 1.5 | 4.5 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 1.3 | 4.0 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
| 1.3 | 6.4 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 1.3 | 5.1 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 1.2 | 6.2 | GO:1904684 | negative regulation of metalloendopeptidase activity(GO:1904684) |
| 1.2 | 5.8 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 1.1 | 4.2 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
| 1.1 | 3.2 | GO:0070428 | granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) |
| 1.0 | 4.1 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 1.0 | 4.9 | GO:0042117 | monocyte activation(GO:0042117) |
| 1.0 | 6.8 | GO:0045346 | regulation of MHC class II biosynthetic process(GO:0045346) |
| 1.0 | 4.8 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.9 | 2.8 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.9 | 2.8 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 0.9 | 2.7 | GO:1904170 | regulation of bleb assembly(GO:1904170) |
| 0.9 | 2.7 | GO:0090649 | rRNA export from nucleus(GO:0006407) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.9 | 6.1 | GO:0035826 | rubidium ion transport(GO:0035826) |
| 0.9 | 5.2 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.9 | 4.3 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
| 0.8 | 5.5 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.8 | 4.7 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.8 | 3.1 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
| 0.8 | 2.3 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.7 | 2.9 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.7 | 2.2 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
| 0.7 | 2.0 | GO:0030421 | defecation(GO:0030421) |
| 0.6 | 6.9 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.6 | 2.4 | GO:0097494 | regulation of vesicle size(GO:0097494) |
| 0.6 | 4.8 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
| 0.6 | 2.3 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.6 | 2.2 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 0.5 | 1.6 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.5 | 1.1 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.5 | 3.8 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.5 | 3.7 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.5 | 3.1 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.5 | 3.4 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.5 | 13.3 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.5 | 3.3 | GO:0030242 | pexophagy(GO:0030242) |
| 0.5 | 2.3 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.4 | 4.5 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.4 | 1.3 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
| 0.4 | 3.1 | GO:1903441 | protein localization to ciliary membrane(GO:1903441) |
| 0.4 | 4.9 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.4 | 3.0 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.4 | 3.8 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
| 0.4 | 3.4 | GO:0015074 | DNA integration(GO:0015074) |
| 0.4 | 2.9 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.4 | 2.5 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.4 | 1.6 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.4 | 1.2 | GO:0006868 | glutamine transport(GO:0006868) |
| 0.4 | 2.4 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.4 | 2.8 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.4 | 1.6 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.4 | 1.6 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.4 | 2.7 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 0.4 | 5.4 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.4 | 1.9 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.4 | 17.2 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.4 | 0.7 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.4 | 1.5 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.4 | 1.1 | GO:1900041 | intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896) |
| 0.4 | 2.5 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.4 | 8.7 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.4 | 1.1 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.4 | 1.1 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.3 | 1.4 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 0.3 | 1.0 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
| 0.3 | 2.1 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.3 | 3.0 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.3 | 5.3 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.3 | 1.0 | GO:0019530 | taurine metabolic process(GO:0019530) |
| 0.3 | 1.3 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.3 | 1.3 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
| 0.3 | 0.3 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.3 | 3.3 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.3 | 1.0 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.3 | 1.6 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.3 | 1.9 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.3 | 1.5 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
| 0.3 | 1.8 | GO:1901072 | glucosamine-containing compound catabolic process(GO:1901072) |
| 0.3 | 1.8 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.3 | 1.5 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.3 | 0.9 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.3 | 0.6 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.3 | 2.4 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.3 | 1.2 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.3 | 1.7 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 0.3 | 2.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.3 | 0.8 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
| 0.3 | 3.1 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.3 | 1.6 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.3 | 0.8 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.3 | 0.8 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.3 | 1.5 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.3 | 2.6 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.3 | 2.8 | GO:0048570 | notochord morphogenesis(GO:0048570) |
| 0.3 | 0.5 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.3 | 2.0 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.2 | 1.5 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.2 | 2.4 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
| 0.2 | 0.9 | GO:0010288 | response to lead ion(GO:0010288) |
| 0.2 | 15.4 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.2 | 6.1 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.2 | 2.4 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.2 | 0.7 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.2 | 0.9 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.2 | 0.7 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
| 0.2 | 1.1 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
| 0.2 | 2.2 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.2 | 1.5 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126) |
| 0.2 | 0.6 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 0.2 | 4.2 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.2 | 0.6 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
| 0.2 | 1.5 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.2 | 0.8 | GO:0030576 | Cajal body organization(GO:0030576) |
| 0.2 | 0.6 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
| 0.2 | 3.9 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.2 | 0.4 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
| 0.2 | 2.9 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.2 | 1.2 | GO:0046502 | uroporphyrinogen III metabolic process(GO:0046502) |
| 0.2 | 0.8 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
| 0.2 | 2.1 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.2 | 0.8 | GO:0052151 | positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) |
| 0.2 | 1.5 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.2 | 0.9 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.2 | 7.7 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.2 | 1.6 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.2 | 1.1 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.2 | 1.6 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.2 | 9.4 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.2 | 1.8 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.2 | 2.7 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.2 | 1.1 | GO:0071971 | extracellular exosome assembly(GO:0071971) regulation of extracellular exosome assembly(GO:1903551) |
| 0.2 | 0.9 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.2 | 8.4 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.2 | 2.1 | GO:0090148 | membrane fission(GO:0090148) |
| 0.2 | 1.6 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.2 | 0.5 | GO:1901250 | regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
| 0.2 | 0.7 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024) |
| 0.2 | 0.5 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.2 | 0.3 | GO:0051124 | synaptic growth at neuromuscular junction(GO:0051124) |
| 0.2 | 0.5 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.2 | 0.3 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
| 0.2 | 1.6 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.2 | 9.1 | GO:0007628 | adult walking behavior(GO:0007628) |
| 0.2 | 1.9 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.2 | 0.8 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
| 0.2 | 0.5 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
| 0.2 | 1.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.2 | 1.4 | GO:2000781 | positive regulation of double-strand break repair(GO:2000781) |
| 0.2 | 1.1 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.2 | 0.8 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.1 | 1.3 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 1.0 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.1 | 3.0 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 8.4 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
| 0.1 | 0.3 | GO:0048550 | negative regulation of pinocytosis(GO:0048550) |
| 0.1 | 1.0 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.1 | 0.6 | GO:0021586 | pons maturation(GO:0021586) |
| 0.1 | 4.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.1 | 0.4 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
| 0.1 | 2.4 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.1 | 1.3 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.1 | 0.6 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055) |
| 0.1 | 2.6 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 0.4 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.1 | 1.4 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.1 | 2.3 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 2.3 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.1 | 1.7 | GO:0006309 | apoptotic DNA fragmentation(GO:0006309) |
| 0.1 | 1.1 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.1 | 1.8 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.1 | 3.8 | GO:0045214 | sarcomere organization(GO:0045214) |
| 0.1 | 2.7 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.1 | 0.7 | GO:0032682 | negative regulation of chemokine production(GO:0032682) |
| 0.1 | 1.7 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.1 | 0.9 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.1 | 0.9 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 6.7 | GO:0007492 | endoderm development(GO:0007492) |
| 0.1 | 10.5 | GO:0043473 | pigmentation(GO:0043473) |
| 0.1 | 1.2 | GO:0006833 | water transport(GO:0006833) |
| 0.1 | 0.7 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 0.4 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.1 | 0.1 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.1 | 8.1 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.1 | 16.6 | GO:0008643 | carbohydrate transport(GO:0008643) |
| 0.1 | 0.5 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.1 | 0.6 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) |
| 0.1 | 1.1 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.1 | 0.4 | GO:2000110 | protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 2.3 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.1 | 1.1 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.1 | 0.5 | GO:0033574 | response to testosterone(GO:0033574) |
| 0.1 | 8.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 0.2 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.1 | 0.3 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.1 | 0.6 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
| 0.1 | 1.1 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 0.4 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 0.1 | 2.4 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.1 | 3.1 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.1 | 2.6 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
| 0.1 | 0.9 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.1 | 0.8 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.1 | 1.0 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.5 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.1 | 0.4 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.1 | 0.3 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.1 | 0.5 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 0.5 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.1 | 0.7 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 0.4 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.1 | 2.7 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.1 | 0.3 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.1 | 0.2 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.1 | 1.2 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.1 | 0.7 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 2.4 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.1 | 0.7 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.1 | 1.8 | GO:0035909 | aorta morphogenesis(GO:0035909) |
| 0.1 | 0.9 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
| 0.1 | 0.7 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.1 | 0.7 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 1.4 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.1 | 0.3 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
| 0.1 | 0.9 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.1 | 0.8 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 0.2 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.1 | 0.3 | GO:0002544 | chronic inflammatory response(GO:0002544) |
| 0.1 | 0.4 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.1 | 0.7 | GO:0033603 | positive regulation of dopamine secretion(GO:0033603) |
| 0.1 | 1.1 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 0.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 0.6 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 1.7 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 0.7 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.1 | 3.4 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
| 0.1 | 0.5 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.1 | 0.4 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.1 | 0.3 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
| 0.1 | 1.0 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.1 | GO:0070162 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 0.2 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.1 | 1.4 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
| 0.1 | 0.3 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.1 | 0.7 | GO:0006681 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
| 0.1 | 0.3 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) B cell chemotaxis(GO:0035754) |
| 0.1 | 0.8 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.1 | 0.1 | GO:0010692 | regulation of alkaline phosphatase activity(GO:0010692) positive regulation of alkaline phosphatase activity(GO:0010694) |
| 0.1 | 0.5 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.1 | 0.2 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.1 | 0.7 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 0.3 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.1 | 0.3 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.1 | 0.9 | GO:0016358 | dendrite development(GO:0016358) |
| 0.1 | 0.1 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 0.1 | 0.8 | GO:0046548 | retinal rod cell development(GO:0046548) |
| 0.1 | 1.2 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
| 0.1 | 0.2 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
| 0.1 | 0.2 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.1 | 0.5 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
| 0.1 | 0.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.2 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.1 | 0.3 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 0.1 | 0.5 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 0.2 | GO:0021972 | corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
| 0.1 | 0.2 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.1 | 1.0 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.1 | 0.3 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.1 | 0.1 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
| 0.1 | 0.3 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.1 | 0.2 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.1 | 0.5 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.2 | GO:0060043 | regulation of cardiac muscle cell proliferation(GO:0060043) |
| 0.0 | 0.4 | GO:0006817 | phosphate ion transport(GO:0006817) |
| 0.0 | 0.0 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 0.0 | 0.3 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.0 | 0.1 | GO:0071073 | positive regulation of phospholipid biosynthetic process(GO:0071073) |
| 0.0 | 0.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 1.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.1 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.0 | 0.1 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.0 | 0.4 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 2.2 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.3 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.1 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
| 0.0 | 0.5 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.2 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.0 | 0.3 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.0 | 0.3 | GO:0051900 | regulation of mitochondrial depolarization(GO:0051900) |
| 0.0 | 1.4 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.3 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 0.2 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.0 | 0.7 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 0.2 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
| 0.0 | 0.3 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.0 | 1.7 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
| 0.0 | 0.2 | GO:0035878 | nail development(GO:0035878) |
| 0.0 | 0.2 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
| 0.0 | 0.8 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.0 | 0.1 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.0 | 0.3 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 0.0 | 1.1 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 0.0 | 0.9 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.0 | 0.1 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.0 | 0.8 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.8 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.1 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.0 | 0.3 | GO:0097286 | iron ion import(GO:0097286) |
| 0.0 | 0.2 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 0.2 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
| 0.0 | 0.1 | GO:0043586 | tongue development(GO:0043586) |
| 0.0 | 0.3 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
| 0.0 | 0.3 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.0 | 1.2 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 2.3 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
| 0.0 | 0.1 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.0 | 0.4 | GO:0048535 | lymph node development(GO:0048535) |
| 0.0 | 0.2 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.0 | 0.5 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 0.2 | GO:0043084 | penile erection(GO:0043084) |
| 0.0 | 0.5 | GO:0031670 | cellular response to nutrient(GO:0031670) |
| 0.0 | 0.5 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.0 | 0.2 | GO:0046322 | negative regulation of fatty acid oxidation(GO:0046322) |
| 0.0 | 0.2 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.0 | 1.0 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 0.1 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) |
| 0.0 | 0.9 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.0 | 0.6 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 3.2 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
| 0.0 | 0.6 | GO:0035411 | catenin import into nucleus(GO:0035411) |
| 0.0 | 0.3 | GO:0030011 | maintenance of cell polarity(GO:0030011) |
| 0.0 | 0.5 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 1.2 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.1 | GO:0061525 | hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619) hindgut development(GO:0061525) |
| 0.0 | 2.7 | GO:0000910 | cytokinesis(GO:0000910) |
| 0.0 | 0.2 | GO:0070884 | calcineurin-NFAT signaling cascade(GO:0033173) regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 0.5 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 1.1 | GO:0048635 | negative regulation of muscle organ development(GO:0048635) |
| 0.0 | 1.1 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.8 | GO:0006739 | NADP metabolic process(GO:0006739) |
| 0.0 | 0.1 | GO:0009052 | pentose-phosphate shunt, non-oxidative branch(GO:0009052) |
| 0.0 | 1.0 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.0 | 0.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.3 | GO:0003170 | heart valve development(GO:0003170) |
| 0.0 | 2.8 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 1.7 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 0.2 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.0 | 0.2 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.3 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.0 | 0.3 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 0.2 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.0 | 0.3 | GO:0001779 | natural killer cell differentiation(GO:0001779) |
| 0.0 | 0.3 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 0.1 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.2 | GO:0017144 | drug metabolic process(GO:0017144) |
| 0.0 | 0.1 | GO:0035247 | peptidyl-arginine omega-N-methylation(GO:0035247) |
| 0.0 | 0.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.0 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142) |
| 0.0 | 0.4 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.0 | 0.1 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.0 | 1.7 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 0.5 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.2 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.0 | 0.1 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.0 | 0.1 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.0 | 0.2 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.3 | GO:0030819 | positive regulation of cyclic nucleotide biosynthetic process(GO:0030804) positive regulation of cAMP biosynthetic process(GO:0030819) |
| 0.0 | 0.3 | GO:0016079 | synaptic vesicle exocytosis(GO:0016079) |
| 0.0 | 0.2 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 0.1 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.0 | 0.1 | GO:0034312 | diol biosynthetic process(GO:0034312) |
| 0.0 | 0.0 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.0 | 0.6 | GO:0006906 | vesicle fusion(GO:0006906) |
| 0.0 | 0.3 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.0 | 0.1 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.0 | 0.3 | GO:0030534 | adult behavior(GO:0030534) |
| 0.0 | 0.8 | GO:0030203 | glycosaminoglycan metabolic process(GO:0030203) |
| 0.0 | 0.1 | GO:0008584 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.0 | 0.1 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.8 | GO:0030010 | establishment of cell polarity(GO:0030010) |
| 0.0 | 0.2 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.0 | 0.2 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.2 | GO:0000422 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
| 0.0 | 0.1 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.0 | 0.3 | GO:0001523 | retinoid metabolic process(GO:0001523) |
| 0.0 | 0.1 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 0.3 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.3 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 0.0 | GO:0035562 | regulation of chromatin binding(GO:0035561) negative regulation of chromatin binding(GO:0035562) |
| 0.0 | 0.1 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
| 0.0 | 0.1 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 14.4 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 1.8 | 7.2 | GO:0019034 | viral replication complex(GO:0019034) |
| 1.4 | 4.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 1.4 | 9.7 | GO:0033263 | CORVET complex(GO:0033263) |
| 1.2 | 3.7 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 1.1 | 3.2 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 1.1 | 4.2 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
| 1.0 | 3.0 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.9 | 3.8 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.8 | 5.9 | GO:0033503 | HULC complex(GO:0033503) |
| 0.8 | 8.2 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.8 | 7.1 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.7 | 2.2 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.7 | 1.4 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.7 | 6.5 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.6 | 10.4 | GO:0043196 | varicosity(GO:0043196) |
| 0.6 | 3.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.6 | 2.5 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.6 | 2.4 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.5 | 4.9 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.5 | 2.7 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.5 | 2.7 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.5 | 4.7 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.5 | 4.1 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.5 | 2.4 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.5 | 2.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.4 | 5.8 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.4 | 4.7 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.4 | 13.5 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.4 | 6.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.4 | 6.5 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.4 | 3.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.4 | 6.8 | GO:0010369 | chromocenter(GO:0010369) |
| 0.4 | 1.1 | GO:0031045 | dense core granule(GO:0031045) |
| 0.3 | 1.7 | GO:0097441 | basilar dendrite(GO:0097441) |
| 0.3 | 1.6 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.3 | 0.7 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.3 | 1.6 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.3 | 2.9 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.3 | 6.1 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.3 | 1.8 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.3 | 2.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.3 | 1.5 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.3 | 2.1 | GO:0071203 | WASH complex(GO:0071203) |
| 0.3 | 0.9 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.3 | 1.1 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.3 | 2.8 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.3 | 4.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.3 | 1.0 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.3 | 2.3 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.3 | 6.1 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.3 | 1.0 | GO:0044308 | axonal spine(GO:0044308) |
| 0.2 | 3.7 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.2 | 0.7 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 0.2 | 0.9 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.2 | 0.9 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 2.3 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.2 | 2.8 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 4.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.2 | 0.9 | GO:0042581 | specific granule(GO:0042581) |
| 0.2 | 1.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.2 | 1.6 | GO:0031415 | NatA complex(GO:0031415) |
| 0.2 | 0.6 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.2 | 0.5 | GO:0098842 | postsynaptic early endosome(GO:0098842) |
| 0.2 | 1.5 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.2 | 1.5 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.2 | 0.3 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.2 | 5.0 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.2 | 1.1 | GO:0005883 | neurofilament(GO:0005883) |
| 0.2 | 1.3 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.2 | 2.7 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 7.2 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 1.6 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 0.1 | 0.4 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.1 | 0.6 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 0.8 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.1 | 1.0 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 0.7 | GO:0051286 | cell tip(GO:0051286) |
| 0.1 | 0.5 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.1 | 0.9 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.1 | 3.0 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 1.1 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.1 | 3.3 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 1.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 2.9 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 1.2 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 1.0 | GO:0045252 | dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.1 | 7.8 | GO:0030117 | membrane coat(GO:0030117) coated membrane(GO:0048475) |
| 0.1 | 1.7 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 0.4 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.1 | 0.9 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.1 | 0.7 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 0.5 | GO:0097361 | CIA complex(GO:0097361) |
| 0.1 | 0.8 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 2.1 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.5 | GO:0031082 | BLOC complex(GO:0031082) |
| 0.1 | 1.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.1 | 15.0 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 0.2 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.1 | 0.1 | GO:0000801 | central element(GO:0000801) |
| 0.1 | 0.3 | GO:0097574 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
| 0.1 | 0.5 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.1 | 2.5 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.1 | 0.8 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 8.9 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.1 | 0.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 1.3 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 0.6 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 17.3 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 0.8 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 0.3 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 0.2 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.1 | 5.8 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 0.2 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.1 | 2.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 0.6 | GO:1904949 | ATPase complex(GO:1904949) |
| 0.1 | 0.4 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.0 | 2.5 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 1.7 | GO:0032153 | cell division site(GO:0032153) cell division site part(GO:0032155) |
| 0.0 | 1.1 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.4 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 1.2 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.5 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.0 | 5.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.2 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 0.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.1 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
| 0.0 | 0.1 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.0 | 0.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 0.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 0.1 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 1.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.0 | 0.4 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 0.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.0 | 24.6 | GO:0005773 | vacuole(GO:0005773) |
| 0.0 | 2.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 1.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 2.2 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.4 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 16.1 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.1 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.1 | GO:0070187 | telosome(GO:0070187) |
| 0.0 | 0.3 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.3 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.1 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.5 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.2 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.7 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 1.6 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 3.5 | GO:0030427 | site of polarized growth(GO:0030427) |
| 0.0 | 3.2 | GO:0030424 | axon(GO:0030424) |
| 0.0 | 2.3 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.0 | 0.1 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.0 | 0.2 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.2 | GO:0032300 | mismatch repair complex(GO:0032300) |
| 0.0 | 0.2 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.6 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.4 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
| 0.0 | 0.6 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 1.1 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 3.5 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 0.2 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.4 | 25.3 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 3.6 | 10.9 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 2.3 | 6.9 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 1.2 | 3.7 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 1.2 | 8.5 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 1.1 | 8.0 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 1.1 | 6.5 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 1.1 | 5.4 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 1.0 | 2.9 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.9 | 3.8 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 0.9 | 21.0 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
| 0.8 | 4.8 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.8 | 12.8 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.7 | 5.0 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.7 | 2.7 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.6 | 3.8 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.6 | 4.4 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.6 | 2.5 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.6 | 3.0 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 0.6 | 4.8 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.6 | 1.7 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
| 0.6 | 2.8 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.6 | 1.7 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.5 | 2.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.5 | 3.0 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.5 | 10.8 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.5 | 4.3 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.5 | 2.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.5 | 5.0 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.4 | 4.2 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.4 | 2.9 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.4 | 1.6 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.4 | 3.1 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.4 | 2.8 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.4 | 7.1 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.4 | 1.1 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.4 | 1.1 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.3 | 2.8 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.3 | 1.0 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.3 | 2.0 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.3 | 3.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.3 | 3.6 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.3 | 1.2 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
| 0.3 | 1.8 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.3 | 3.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.3 | 6.5 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.3 | 0.8 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
| 0.3 | 1.1 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.3 | 3.2 | GO:0035615 | clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.3 | 1.6 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.3 | 1.3 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
| 0.3 | 3.1 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.3 | 0.8 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.3 | 1.0 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
| 0.2 | 1.5 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.2 | 6.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 4.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.2 | 1.1 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.2 | 0.7 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.2 | 3.0 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.2 | 2.5 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.2 | 2.2 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
| 0.2 | 1.6 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.2 | 0.7 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.2 | 1.3 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.2 | 0.9 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.2 | 0.6 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 0.2 | 3.4 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 1.4 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.2 | 1.8 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.2 | 3.8 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
| 0.2 | 0.6 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.2 | 0.6 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 0.2 | 1.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.2 | 0.6 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.2 | 0.9 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.2 | 7.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.2 | 5.8 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.2 | 0.9 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.2 | 1.9 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.2 | 0.7 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.2 | 5.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.2 | 9.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.2 | 0.5 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.2 | 10.3 | GO:0017022 | myosin binding(GO:0017022) |
| 0.2 | 1.1 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.2 | 0.8 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
| 0.2 | 0.3 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.1 | 0.4 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 0.4 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.1 | 0.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.1 | 2.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 3.1 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 0.5 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.1 | 0.5 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
| 0.1 | 2.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 14.9 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 1.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.1 | 0.7 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.1 | 0.6 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
| 0.1 | 0.4 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.1 | 0.6 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.1 | 0.5 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 2.8 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 5.1 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.6 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
| 0.1 | 0.8 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.7 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 0.3 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.1 | 0.9 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 1.2 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 2.9 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.1 | 1.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 2.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 0.9 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.1 | 9.7 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 2.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.9 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.1 | 4.7 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.1 | 3.4 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 2.2 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.1 | 0.5 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 4.2 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 25.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 0.4 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 0.3 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.1 | 4.0 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.1 | 1.0 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 3.2 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 1.5 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 0.9 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.1 | 1.4 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.1 | 6.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 0.5 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.1 | 1.6 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 0.2 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.1 | 0.8 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 0.3 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.1 | 24.4 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 1.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.3 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
| 0.1 | 3.1 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 0.2 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
| 0.1 | 0.7 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.1 | 0.5 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 0.7 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 2.4 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 0.2 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.1 | 1.6 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.1 | 0.2 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 31.4 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.1 | 0.2 | GO:0004458 | D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898) |
| 0.1 | 0.3 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 0.1 | 0.3 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.1 | 0.3 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
| 0.1 | 0.2 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.1 | 1.4 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.1 | 0.3 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.1 | 0.3 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.1 | 0.2 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.1 | 1.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.1 | 4.4 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.1 | 0.2 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.1 | 0.5 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.1 | 0.2 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.1 | 0.6 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.1 | 4.2 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.1 | 1.0 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 0.5 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
| 0.1 | 0.3 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.1 | 0.3 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 1.0 | GO:0016229 | steroid dehydrogenase activity(GO:0016229) |
| 0.1 | 1.7 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.9 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 2.8 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.1 | 2.2 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
| 0.1 | 4.7 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.1 | 1.2 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.1 | 3.3 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.1 | 0.3 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.0 | 0.5 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 0.2 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.0 | 2.7 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 1.8 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 1.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.0 | 0.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.5 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
| 0.0 | 0.1 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.0 | 0.5 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.2 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 0.3 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 4.4 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.0 | 0.2 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.0 | 2.5 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.1 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.0 | 0.1 | GO:0010181 | FMN binding(GO:0010181) |
| 0.0 | 0.3 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.2 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.0 | 0.8 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.3 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 0.2 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.0 | 0.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 1.0 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.0 | 0.1 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.0 | 0.1 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.0 | 0.4 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 0.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.7 | GO:0050661 | NADP binding(GO:0050661) |
| 0.0 | 0.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.4 | GO:1901505 | carbohydrate derivative transporter activity(GO:1901505) |
| 0.0 | 0.6 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.0 | 0.1 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.0 | 0.5 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.2 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.0 | 0.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.1 | GO:0001846 | opsonin binding(GO:0001846) |
| 0.0 | 0.4 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.9 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.1 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.0 | 0.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.2 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.0 | 0.2 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 0.0 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 0.1 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.0 | 0.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.0 | 0.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 0.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 0.4 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.7 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 0.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 1.5 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.2 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.7 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 0.2 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.6 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.1 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.1 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.0 | 0.9 | GO:0016209 | antioxidant activity(GO:0016209) |
| 0.0 | 0.2 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 0.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.0 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) mismatched DNA binding(GO:0030983) |
| 0.0 | 0.1 | GO:0004385 | guanylate kinase activity(GO:0004385) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 10.5 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
| 0.2 | 2.1 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.2 | 2.4 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
| 0.2 | 3.2 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.1 | 4.9 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.1 | 7.9 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
| 0.1 | 2.0 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 2.2 | PID_ATM_PATHWAY | ATM pathway |
| 0.1 | 2.2 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 9.5 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.1 | 10.2 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.1 | 0.5 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 0.5 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.1 | 1.0 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.1 | 3.4 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 1.1 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 1.8 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.1 | 1.3 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.1 | 0.4 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 2.0 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 1.5 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.1 | 1.5 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 1.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.6 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.0 | 0.3 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 2.9 | PID_P73PATHWAY | p73 transcription factor network |
| 0.0 | 3.3 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 1.1 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 1.0 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.0 | 1.4 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.0 | 0.7 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.2 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 0.9 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.0 | 3.0 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 0.9 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.0 | 1.6 | PID_CDC42_PATHWAY | CDC42 signaling events |
| 0.0 | 0.1 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.9 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
| 0.0 | 0.1 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.2 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 7.9 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.4 | 22.5 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.4 | 2.9 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.4 | 5.0 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.3 | 4.9 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.3 | 11.0 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.3 | 8.6 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.3 | 4.3 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
| 0.3 | 2.8 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.3 | 5.9 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.3 | 1.6 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.3 | 6.9 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.3 | 7.9 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.2 | 4.1 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 2.8 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.2 | 4.2 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.2 | 2.4 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.2 | 5.7 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.2 | 1.7 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.2 | 1.3 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.2 | 1.2 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 1.3 | REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | Genes involved in Acetylcholine Binding And Downstream Events |
| 0.1 | 2.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 1.0 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 3.1 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 2.5 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 1.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 4.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 4.6 | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | Genes involved in Formation of RNA Pol II elongation complex |
| 0.1 | 0.6 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 1.1 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 1.8 | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
| 0.1 | 2.2 | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.1 | 8.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 1.3 | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.1 | 0.6 | REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.1 | 2.0 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.1 | 1.1 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 0.2 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.1 | 0.6 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.1 | 0.9 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 2.0 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 3.6 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 6.3 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.3 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.8 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.4 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.2 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 1.1 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.2 | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | Genes involved in Integration of energy metabolism |
| 0.0 | 0.7 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.0 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.6 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 3.1 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.7 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 1.8 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.8 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.2 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.0 | 0.4 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.6 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 1.1 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 1.4 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
| 0.0 | 0.2 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.3 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.0 | 0.9 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.8 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.3 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.7 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.2 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.2 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.2 | REACTOME_ARMS_MEDIATED_ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.0 | 0.2 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 2.0 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.2 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.3 | REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
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